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CHAPTER 12 Chromosomal Basis of Inheritance, Sex linkage
CHAPTER 12 Chromosomal Basis of Inheritance, Sex linkage

... (2) The pistil contains female gametophytes, and consists of a stigma (the surface to which pollen sticks), a style, down which the pollen tube grows, and an ovary at the base which contains the ovules. Each ovule contains a female gametophyte (embryo sac) with a single egg cell. After fertilization ...
A Single Arabidopsis Gene Encodes Two
A Single Arabidopsis Gene Encodes Two

... D627N mutation in DXS. It is therefore likely that the phenotype of these mutants might be associated to the temperature sensitivity of the corresponding DXS or G11 mutant enzymes, both of them involved in the production of photosynthesis-related isoprenoids (Fig. 1). A second partial loss-of-functi ...
Single-Gene Inheritance Single-Gene Inheritance
Single-Gene Inheritance Single-Gene Inheritance

... Single-gene inheritance patterns are useful for gene discovery not only in experimental genetics of model organisms, but also in applied genetics. An important example is found in human genetics. Many human disorders, such as cystic fibrosis and Tay-Sachs disease, are inherited as a single mutant ge ...
Functional and ecological impacts of horizontal gene transfer in
Functional and ecological impacts of horizontal gene transfer in

... uneven: many microbial eukaryotes and plant mitochondria are rich in examples of HGT [6,8–13], whilst other lineages appear to be relatively immune to acquiring new genes. At the same time, some genes are commonly transferred, whilst others are more static. The variable suseceptibility of different ...
MOLECULAR DIAGNOSIS OF HEREDITARY NONPOLYPOSIS
MOLECULAR DIAGNOSIS OF HEREDITARY NONPOLYPOSIS

A genetic screen in zebrafish identifies the mutants
A genetic screen in zebrafish identifies the mutants

... potential of uncovering both developmental and pathological processes that contribute to this phenotype. Our laboratory has used insertional mutagenesis to generate over 400 lines of zebrafish bearing mutations in 315 genes that are essential for embryonic development, and the mutated gene has been ...
Playing by pair-rules?
Playing by pair-rules?

... insects),(reviewed in Ref. 4) crustaceans,(5–8) myriapods (millipedes and centipedes)(9) and chelicerates (spiders, mites, scorpions and horseshoe crabs)(10–12) (Fig. 1). In all cases, wg stripes lie adjacent and anterior to stripes of en and these observations, together with functional studies in t ...
Recombination in HIV and the evolution of drug resistance: for better
Recombination in HIV and the evolution of drug resistance: for better

... mutation, recombination and superinfection on the evolution of drug resistance. Model We consider two loci with two alleles (a/A and b/B) coding for drug sensitivity (wild type, lowercase) and drug resistance (mutant, uppercase). Thus we have four types of proviruses, which are fully sensitive (ab), ...
SPATULA, a bHLH carpel development gene
SPATULA, a bHLH carpel development gene

... develop specialised tissues that facilitate the passage of the male gametophyte from the exterior to the ovules located within. These tissues usually develop from the carpel margins and include a stigma on which pollen alights, and transmitting tissues within the style and ovary through which the po ...
Pax1, Pax9, Vertebral column, Chondrogenesis, Proliferation
Pax1, Pax9, Vertebral column, Chondrogenesis, Proliferation

... the two neighboring loci dco and P3670 (or X94917), which are both uncovered by the deficiencies PGX8 and PH3 (Fig. 6A); and (iii) the P-element insertion chromosome P1447 carries a closely linked lethal mutation, which is uncovered by the deficiency Df(3R)PGX4 (J. Szidonya, personal communication, ...
Cerberus regulates left–right asymmetry of the embryonic head and
Cerberus regulates left–right asymmetry of the embryonic head and

... stage 12–14, the direction of heart looping and head turning was scored. When cCer was misexpressed on the right side of stage 6–7 embryos, 10/35 embryos (28%) showed inverted heart looping, whereas none of the 26 embryos that had received mock-transfected cells on the right side showed reversed loo ...
Determining the cause of patchwork HBA1 and HBA2 genes
Determining the cause of patchwork HBA1 and HBA2 genes

... genes are also identical in their 5’untranslated regions, the first intron (IVSI) and all three coding exons. In the second intron (IVSII), only two sites of difference exist: a single nucleotide difference at IVSII,55 (G in HBA1 and T in HBA2), and the substitution of an octanucleotide in HBA1 (pos ...
Woolfe, 2005
Woolfe, 2005

... Average of 200 embryos screened per control ...
CHAPTER 15 THE CHROMOSOMAL BASIS OF INHERITANCE
CHAPTER 15 THE CHROMOSOMAL BASIS OF INHERITANCE

Molecular Analysis of the Coprinus cinereus Mating Type A Factor
Molecular Analysis of the Coprinus cinereus Mating Type A Factor

Changes in Plasma Low-Density Lipoprotein (LDL)
Changes in Plasma Low-Density Lipoprotein (LDL)

... results of Wisemann et al (18). Compared with their study, our hypothyroid patients had a similar age and sex distribution, and the degree of hypothyroidism and changes in lipoproteins were equal. The frequency of the presence of an AvaII site in the hypothyroid patients was similar. To exclude an i ...
Genetic Mosaics and the Germ Line Lineage
Genetic Mosaics and the Germ Line Lineage

... embryo, eventually arriving near the endodermal yolk sac, where they are incorporated into the surrounding gonadal tissue developing from somatic cells [1,2,8–10]. A number of molecular markers, including VASA, DAZL, NANOG, c-KIT, and POU5F1, have been described in human embryonic germ cells; howeve ...
Full Text - The International Journal of Developmental Biology
Full Text - The International Journal of Developmental Biology

... gene Hyal5 very close to PH-20 in the genome (Kim et al., 2005). The role of hyaluronidase in sperm-egg interaction will be concluded when we see the binding ability impaired sperm from Hyal5 knockout or PH-20 and Hyal5 double knockout mice. There are more factors suggested to be involved in sperm– ...
Diabetes- 2010 - The Stephens Lab
Diabetes- 2010 - The Stephens Lab

... a form of GLP-1 that is resistant to destruction. Such forms of GLP-1 have already been found, and the source is delightfully unexpected--the poisonous saliva of the Gila monster lizard. GLP-1 (called exendin-4) from these reptiles has a few key differences from the form found in humans, one consequ ...
Biogenesis, Structure, and Function of Integral Membrane Proteins
Biogenesis, Structure, and Function of Integral Membrane Proteins

... in vivo. Our initial results were both surprising and unpredicted (Herskovits et al, 2000). (1) We demonstrated that of the major components of the system only the SRP-receptor is essential for membrane protein expression and membrane targeting of ribosomes (Seluanov and Bibi, 1997; Herskovits and B ...
Gene families and evolution of trehalose
Gene families and evolution of trehalose

... expressed as a fusion protein with green fluorescent protein in tobacco cells, indicating that the S. lepidophylla TPS1 is likely to be cytosolic (van Dijck et al. 2002). Removal of the extension from the S. lepidophylla TPS1 and A. thaliana TPS1 dramatically increased the catalytic activity of the e ...
Lecture 6 Translation
Lecture 6 Translation

... • Nucleotides specify the amino-acid sequence in proteins with four different nucleotides. A, C, G and U. • A three letter code (using three of the four nucleotides) generates 64 possible combinations or CODONS. • These 64 combinations are more than enough to codify for the 20 amino acids that forms ...
1903. - Sutton, Walter S. The chromosomes in heredity. Biological
1903. - Sutton, Walter S. The chromosomes in heredity. Biological

... they represent. In other words, it is probable that specific differences and individual variations are alike traceable to a common source, which is a difference in the constitution of homologous chromatin entities. Slight differences in homologues would mean corresponding, slight variations in the c ...
Galaxy Basics: DataSet Manipulation inside of Galaxy
Galaxy Basics: DataSet Manipulation inside of Galaxy

Other Blood Group Systems
Other Blood Group Systems

...  Unfortunately, we only get to review the most relevant antigens  We will discuss each of these major antigens, their antibodies, and the clinical significance of each ...
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NEDD9

Neural precursor cell expressed developmentally down-regulated protein 9 (NEDD-9) is a protein that in humans is encoded by the NEDD9 gene. NEDD-9 is also known as enhancer of filamentation 1 (EF1), CRK-associated substrate-related protein (CAS-L), and Cas scaffolding protein family member 2 (CASS2). An important paralog of this gene is BCAR1.
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