Genomic Research to Identify Novel Pathways in the Development
... The SNP in DAB2IP discovered by GWAS also associates with coronary artery disease, peripheral arterial disease, venous thromboembolism, and pulmonary embolism but shows no association with any classical CHD risk factors [40, 41]. DAB2IP, located on Chromosome 9q33, is a GTPase activating protein tho ...
... The SNP in DAB2IP discovered by GWAS also associates with coronary artery disease, peripheral arterial disease, venous thromboembolism, and pulmonary embolism but shows no association with any classical CHD risk factors [40, 41]. DAB2IP, located on Chromosome 9q33, is a GTPase activating protein tho ...
Information Encoding in Biological Molecules: DNA and
... • sequences will show up in Jalview along with genomic sequence and three-frame translation Lab 5.2 ...
... • sequences will show up in Jalview along with genomic sequence and three-frame translation Lab 5.2 ...
Gill: Human Disease Genomics
... correlations with human disease & traits. 2 Genotype customers for as many informative loci as is commercially viable. 3 Offer counseling for your findings, and their meaning. 4 Ask customers to phenotype themselves. 5 Discover new associations! http://cs273a.stanford.edu [Bejerano Fall16/17] ...
... correlations with human disease & traits. 2 Genotype customers for as many informative loci as is commercially viable. 3 Offer counseling for your findings, and their meaning. 4 Ask customers to phenotype themselves. 5 Discover new associations! http://cs273a.stanford.edu [Bejerano Fall16/17] ...
Hereditary Colorectal Cancer
... interval defined by critical recombinants in Lynch syndrome families linked to a 2p locus. The gene was 2802 bp in length, and a missense mutation was found in 11 affected members of 1 kindred, a splice site mutation in another, and a nonsense mutation in another. Both germline and somatic mutations ...
... interval defined by critical recombinants in Lynch syndrome families linked to a 2p locus. The gene was 2802 bp in length, and a missense mutation was found in 11 affected members of 1 kindred, a splice site mutation in another, and a nonsense mutation in another. Both germline and somatic mutations ...
Overview of the genes of watermelon1
... morphological and resistance gene mutants. The genes control traits that can be grouped into seed and seedling traits, vine traits, flower traits, fruit traits, and resistance traits. This article includes a review of traits that result from these genes and their interaction, as well as future resea ...
... morphological and resistance gene mutants. The genes control traits that can be grouped into seed and seedling traits, vine traits, flower traits, fruit traits, and resistance traits. This article includes a review of traits that result from these genes and their interaction, as well as future resea ...
Amino Acids
... HbA has contact with higher glucose concs during the 120 d lifetime of these cells ...
... HbA has contact with higher glucose concs during the 120 d lifetime of these cells ...
Origin of the eukaryotic cell
... Since places of different versions of Hsps in the content of three domains are still mysterious, it would be interesting to look at the whole picture within tree of life and to try to untangle the evolutionary relationship among eukaryotes, bacteria and archaea. Questions concerning origin of mitoch ...
... Since places of different versions of Hsps in the content of three domains are still mysterious, it would be interesting to look at the whole picture within tree of life and to try to untangle the evolutionary relationship among eukaryotes, bacteria and archaea. Questions concerning origin of mitoch ...
Stage- and Tissue-Specific Expression of Ethylene Receptor
... screening and with RD on the second round. A full-length cDNA clone with 74.1% nucleotide homology with ETR1 was isolated by this procedure (Table I). The deduced amino acid sequence had the RD as well as the other two domains, indicating that it is a homolog of ETR1 (Fig. 1B); therefore, the corres ...
... screening and with RD on the second round. A full-length cDNA clone with 74.1% nucleotide homology with ETR1 was isolated by this procedure (Table I). The deduced amino acid sequence had the RD as well as the other two domains, indicating that it is a homolog of ETR1 (Fig. 1B); therefore, the corres ...
Loss of the GP46/M-2 surface membrane
... been demonstrated, in conjunction with certain adjuvants, to elicit protective immunity against infection caused by L. amazonensis [4]. Structural studies indicate that the GP46/M-2 molecule is a glycoprotein molecule [3] which is attached to the surface membrane via a phosphatidylinositol-linked li ...
... been demonstrated, in conjunction with certain adjuvants, to elicit protective immunity against infection caused by L. amazonensis [4]. Structural studies indicate that the GP46/M-2 molecule is a glycoprotein molecule [3] which is attached to the surface membrane via a phosphatidylinositol-linked li ...
Activation of the Interleukin-3 Gene by Chromosome
... The final proof of our thesis must await additional data. In particular, from the study of additional clinical samples, it will be necessary to document that the IL-3 receptor is present on the leukemic cells and that anti-IL-3 antibody decreases proliferation of the leukemia in vitro. An important ...
... The final proof of our thesis must await additional data. In particular, from the study of additional clinical samples, it will be necessary to document that the IL-3 receptor is present on the leukemic cells and that anti-IL-3 antibody decreases proliferation of the leukemia in vitro. An important ...
Gibberellin Regulates Mitochondrial Pyruvate Dehydrogenase
... control and PDK1 RNAi transgenic plants OsPDK1 expression was up-regulated by GA3 at the transcript level and was repressed in PDK1 RNAi transgenic rice. To examine whether mtPDH activity was directly affected by GA3 or by expression of PDK1 RNAi, a series of mtPDH assays were performed. Two-week-ol ...
... control and PDK1 RNAi transgenic plants OsPDK1 expression was up-regulated by GA3 at the transcript level and was repressed in PDK1 RNAi transgenic rice. To examine whether mtPDH activity was directly affected by GA3 or by expression of PDK1 RNAi, a series of mtPDH assays were performed. Two-week-ol ...
(Japan), organized by Nori Satoh
... homeotic posteriorization is a shared derived feature of urochordates. We discuss possible relationships of altered roles of RA in urochordate development to genomic events, such as rupture of the Hox-cluster, in the context of a new understanding of chordate phylogeny. (Cañestro and Postlethwait, 2 ...
... homeotic posteriorization is a shared derived feature of urochordates. We discuss possible relationships of altered roles of RA in urochordate development to genomic events, such as rupture of the Hox-cluster, in the context of a new understanding of chordate phylogeny. (Cañestro and Postlethwait, 2 ...
fulltext - DiVA portal
... Background: Analysis of the Escherichia coli collection of reference strains (ECOR) for the presence of the gene locus clyA, which encodes the pore-forming protein ClyA (cytolysin A), revealed that a non-functional clyA locus is common among certain extraintestinal pathogenic E. coli (ExPEC). In fac ...
... Background: Analysis of the Escherichia coli collection of reference strains (ECOR) for the presence of the gene locus clyA, which encodes the pore-forming protein ClyA (cytolysin A), revealed that a non-functional clyA locus is common among certain extraintestinal pathogenic E. coli (ExPEC). In fac ...
SMN1
... Mechanisms proposed to explain how reduced SMN levels cause SMA According to one hypothesis, reduced SMN levels result in reduced assembly of Sm proteins onto snRNA. This unevenly alters the levels of specific endogenous snRNPs, such as those used to splice minor introns (particularly U11) from pr ...
... Mechanisms proposed to explain how reduced SMN levels cause SMA According to one hypothesis, reduced SMN levels result in reduced assembly of Sm proteins onto snRNA. This unevenly alters the levels of specific endogenous snRNPs, such as those used to splice minor introns (particularly U11) from pr ...
Adaptive Evolution of Proteins Secreted during Sperm Maturation
... Although the testis is the site of spermatogenesis, other male reproductive organs play central roles in male fertility, such as the epididymis and several accessory glands including the seminal vesicles, prostate, coagulating glands, and bulbourethral glands. A recent study of ejaculated proteins f ...
... Although the testis is the site of spermatogenesis, other male reproductive organs play central roles in male fertility, such as the epididymis and several accessory glands including the seminal vesicles, prostate, coagulating glands, and bulbourethral glands. A recent study of ejaculated proteins f ...
Dickkopf1 Is Required for Embryonic Head Induction
... 1997b; Wodarz and Nusse, 1998). Cerberus is a multifunctional inhibitor of BMP, Nodal, and Wnt signals (Piccolo et al., 1999). Wif-1 contains domains with homology to EGF repeats (Hsieh et al., 1999). These Wnt inhibitors have been implicated in the repression of the canonical Wnt/-catenin signalin ...
... 1997b; Wodarz and Nusse, 1998). Cerberus is a multifunctional inhibitor of BMP, Nodal, and Wnt signals (Piccolo et al., 1999). Wif-1 contains domains with homology to EGF repeats (Hsieh et al., 1999). These Wnt inhibitors have been implicated in the repression of the canonical Wnt/-catenin signalin ...
Production of Diploid Male Gametes in Arabidopsis
... GIG1 and TAM/CYCA2;1, two proteins involved in progression of the meiotic cell cycle, cause a complete loss of MII, generating highly homozygous 2n gametes in both male and female meiosis (d’Erfurth et al., 2009, 2010). Spindle-based meiotic restitution mechanisms have been reported in both Arabidop ...
... GIG1 and TAM/CYCA2;1, two proteins involved in progression of the meiotic cell cycle, cause a complete loss of MII, generating highly homozygous 2n gametes in both male and female meiosis (d’Erfurth et al., 2009, 2010). Spindle-based meiotic restitution mechanisms have been reported in both Arabidop ...
13-3
... beneficial variations. Some negatively disrupt gene function. Many if not most mutations are neutral; they have little or no effect on the expression of genes or the function of the proteins for which they code. Whether a mutation is negative or beneficial depends on how its DNA changes relative to th ...
... beneficial variations. Some negatively disrupt gene function. Many if not most mutations are neutral; they have little or no effect on the expression of genes or the function of the proteins for which they code. Whether a mutation is negative or beneficial depends on how its DNA changes relative to th ...
Phytoalexin-Deficient Mutants of Arabidopsis Reveal That
... result in specific recognition by plants carrying corresponding resistance ( R ) genes (FLOR 1971).Gene-forgene recognition oftenleads to expression of the hypersensitive response (HR), a programmed cell death response thatis the hallmark of many of these interactions (MITTLER and LAM 1996; RYERSON ...
... result in specific recognition by plants carrying corresponding resistance ( R ) genes (FLOR 1971).Gene-forgene recognition oftenleads to expression of the hypersensitive response (HR), a programmed cell death response thatis the hallmark of many of these interactions (MITTLER and LAM 1996; RYERSON ...
mtr function Background Luis M. Corrochano
... of neutral aliphatic, and aromatic amino acids, like tryptophan (Koo and Stuart 1991, Dillon and Stadler 1994). In addition, the MTR permease allows the entry of toxic amino acid analogs, like p-fluorophenylalanine (FPA) or 4-methyltryptrophan, in the cell. The name of the locus, mtr, stands for met ...
... of neutral aliphatic, and aromatic amino acids, like tryptophan (Koo and Stuart 1991, Dillon and Stadler 1994). In addition, the MTR permease allows the entry of toxic amino acid analogs, like p-fluorophenylalanine (FPA) or 4-methyltryptrophan, in the cell. The name of the locus, mtr, stands for met ...
Age study
... accurately describe the variables that affect the response variables (gene expression). Thus, by incorporating the same variables into the ANOVA that are affecting the microarray data, the technical effects can be accounted for, and the biologically relevant effects become more apparent. Additionall ...
... accurately describe the variables that affect the response variables (gene expression). Thus, by incorporating the same variables into the ANOVA that are affecting the microarray data, the technical effects can be accounted for, and the biologically relevant effects become more apparent. Additionall ...
ACTIN-RELATED PROTEIN6 Regulates Female Meiosis By
... SPOROCYTELESS promoter fused to the b-glucuronidase reporter gene; Ito et al., 2004) as a marker for differentiation of the archesporial cell to a megasporocyte (Yang et al., 1999) at the distal end of each ovule primordium (Schneitz et al., 1995). Wild-type and arp6-1 mutant ovules showed similar G ...
... SPOROCYTELESS promoter fused to the b-glucuronidase reporter gene; Ito et al., 2004) as a marker for differentiation of the archesporial cell to a megasporocyte (Yang et al., 1999) at the distal end of each ovule primordium (Schneitz et al., 1995). Wild-type and arp6-1 mutant ovules showed similar G ...
File
... beneficial variations. Some negatively disrupt gene function. Many if not most mutations are neutral; they have little or no effect on the expression of genes or the function of the proteins for which they code. Whether a mutation is negative or beneficial depends on how its DNA changes relative to ...
... beneficial variations. Some negatively disrupt gene function. Many if not most mutations are neutral; they have little or no effect on the expression of genes or the function of the proteins for which they code. Whether a mutation is negative or beneficial depends on how its DNA changes relative to ...
