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Classification of plant-pathogenic mycoplasma
Classification of plant-pathogenic mycoplasma

... Based on Southern hybridization with a DNA fragment of an MLO associated with aster yellows, a differentiation between organisms inducing decline symptoms and those causing floral virescence has been proposed (Kuske et al., 1991). Although several organisms have been differentiated using these metho ...
Compressed q-gram Indexing for Highly Repetitive Biological
Compressed q-gram Indexing for Highly Repetitive Biological

... of all humans. Less than one decade later, DNA sequencing technologies have become so fast and cost-effective that sequencing individual genomes will soon become a common task [1], [2], [3]. Huge DNA collections are at the next corner. The computational challenges posed by handling collections of th ...
DHFR catalyzes the transfer of a hydride from NADPH to
DHFR catalyzes the transfer of a hydride from NADPH to

... active site play a role in promoting the release of the product, tetrahydrofolate. In particular the Met20 loop helps stabilize the nicotinamide ring of the NADPH to promote the transfer of the hydride from NADPH to dihydrofolate. Since folate is needed by rapidly dividing cells to make thymine, thi ...
Genome-Wide Gene Expression Effects of Sex Chromosome
Genome-Wide Gene Expression Effects of Sex Chromosome

... effects on heterochromatin that result from transmission through males or females and produce parent-of-origin effects on the expression of visible markers in or near the heterochromatic regions (Lloyd 2000; Maggert and Golic 2002). The link between imprinting and heterochromatin in Drosophila is su ...
BIO 101 Lab OBJECTIVES
BIO 101 Lab OBJECTIVES

... 2. Know how positive and negative controls are used. 3. Know the subunits that make up these 4 groups: carbohydrates (monosaccharides, disaccharides and polysaccharides), proteins, lipids and nucleic acids. 4. Know what the following reagents are used to test for and what a positive result would loo ...
Germline Mutation in NLRP2 (NALP2) in a Familial
Germline Mutation in NLRP2 (NALP2) in a Familial

... KvDMR1, we analysed methylation levels at the TND (6q24), SNRPN (15q13) and PEG1 (7q32) DMRs. Both affected siblings (and all controls) had normal methylation levels at the TND and SNRPN DMRs but Child 2 demonstrated partial loss of methylation at the PEG1 DMR (Figure 3). ...
The structure of RNase E at the core of the RNA
The structure of RNase E at the core of the RNA

... only one of the bases forms a hydrogen bond with the protein; Lys106 contacts the exocyclic oxygen of the base at position -1 with regard to the scissile phosphate. This direct contact may explain the preference for G or U at this position25. Aside from that contact, there is no sequence recognition ...
Adventitious root formation in rice requires OsGNOM1 and
Adventitious root formation in rice requires OsGNOM1 and

... The fibrous root system in cereals comprises primarily adventitious roots (ARs), which play important roles in nutrient and water uptake. Current knowledge regarding the molecular mechanism underlying AR development is still limited. We report here the isolation of four rice (Oryza sativa L.) mutant ...
Genetics of fibrosing lung diseases REVIEW
Genetics of fibrosing lung diseases REVIEW

... the affected subjects, suggesting the influence of modifier genes and/or environmental factors. Surfactant protein C gene variations have not, however, been associated with sporadic cases, i.e. idiopathic pulmonary fibrosis (IPF). Susceptibility to IPF probably involves a combination of polymorphism ...
Nucleus Evidence 1
Nucleus Evidence 1

... Evidence #1: Diabetes ...
Gene Section USP1 (ubiquitin specific peptidase 1) Atlas of Genetics and Cytogenetics
Gene Section USP1 (ubiquitin specific peptidase 1) Atlas of Genetics and Cytogenetics

... include USP12, USP35, USP38, and USP46. ...
Albinism - OG
Albinism - OG

... gene from the father and the albinism gene from the mother both have to passed on to the kid.  The kid needs to have both albinism genes from each parent to have albinism, not just one.  If they only have one albino gene, then the child will be considered a “carrier” of an albinism gene.  Albinis ...
ARTICLE A wide variety of mutations in the parkin gene are
ARTICLE A wide variety of mutations in the parkin gene are

... Point mutations were present in eight families, that included 20 patients (Table 2). The patients of family IT-020 with a truncating mutation on one allele and a missense mutation on the other allele were classified in the missense mutation group, assuming that missense mutations may be less deleter ...
Functional Genomics
Functional Genomics

... association. It was the comprehensive nature of whole-genome sequences that made this a feasible approach to identifying function. Thus the unique aspect of functional genomics in an organism whose genome in known completely is the ability to monitor simultaneously potentially all events, whether it ...
Antibiotic resistance genes and identification of staphylococci
Antibiotic resistance genes and identification of staphylococci

... respectively, can be explained by their usual genetic locations. In fact, the presence of tet(K) gene on small multicopy plasmids and tet(M) on conjugative transposons (Tn916–Tn1545 family) contributes to the spread of these determinants (Chopra and Roberts, 2001). Furthermore, we found tet(O) only ...
Часть 1.  - Ассоциация синдрома Ретта
Часть 1. - Ассоциация синдрома Ретта

... terminal 3' nucleotides, one of which is complementary to the normal DNA sequence and the other to the changed nucleotide in the mutant DNA.8,9 Under carefully controlled conditions a primer with its terminal 3' nucleotide mismatched will not function properly and no amplification occurs from the wi ...
第六届植物分子生物学暑期研讨班专家资料介绍
第六届植物分子生物学暑期研讨班专家资料介绍

... genetic studies in Arabidopsis, intracellular signaling pathways linking cell surface receptors to nuclear components remain poorly understood. In animals and yeast, G proteins or GTPases are pivotal switches that turn on and off intracellular signaling pathways by cycling between GTP-bound active a ...
software development and application in bioinformatics: single
software development and application in bioinformatics: single

... d. MAQ aligner: MAQ stands for Mapping and Assembly with Quality. It is a commonly used linux application for short reads alignment and SNP calling [11]. MAQ supports Illumina reads, and includes functions that make it able to handle next-generation sequencing data [11] and AB SOLiD (a parallel next ...
Lecture 6 Translation
Lecture 6 Translation

... • g. If each anticodon had to be a perfect match to each codon, we would expect to find 61 types of tRNA, but the actual number is about 45. This is because the anticodons of some tRNAs recognize more than one codon. • This is possible because the rules for base pairing between the third base of th ...
General Introduction
General Introduction

... produces a smooth exterior) or a w (for the alternative allele producing wrinkling if the seed is allowed to become dry). This gene produces an enzyme involved in the production of starch in the developing seed. You will remember that starch is a polysaccharide composed of many glucose molecules tha ...
Maternal and paternal genomes contribute equally to the
Maternal and paternal genomes contribute equally to the

... embryonic development before activation of the zygotic genome1. In plants, an analogous period of prolonged maternal control over embryogenesis is thought to occur based on some gene-expression studies2–6. However, other gene-expression studies and genetic analyses show that some transcripts must de ...
Multifractal characterisation of length sequences of coding and
Multifractal characterisation of length sequences of coding and

... One can study the DNA sequences in detail by considering the order in which four kinds of nucleotides of DNA are assembled, namely adenine (a), cytosine (c), guanine (g), and thymine (t). There has been considerable interest in the 3nding of long-range correlation (LRC) in DNA sequences at this leve ...
Lessons from Functional Analysis of Genome
Lessons from Functional Analysis of Genome

... growth. Compounds targeting MYC might thus be used in a much broader set of patients than the current mechanismbased cancer drugs. It might also be more difficult for a cancer to escape MYC loss, as no other genes except N-MYC and L-MYC are known that can compensate for its activity. However, MYC is ...
HTML Web Page That Shows Its Own Source Code
HTML Web Page That Shows Its Own Source Code

... of) the source code, but in that source code we keep the X as shown here (or some other symbol) to mark the place where the DNA must be inserted. 9. As marker, we will use a character that does not otherwise appear in the scripts (X seems fine). However, in order to recognize the marker, we need a w ...
Probing the evolution of appendage specialization by
Probing the evolution of appendage specialization by

... example, changes in Hox gene regulation (2–6), in Hox coding sequences (7, 8), and in the interactions of Hox genes with their downstream targets (9, 10) have all been implicated in the evolution of segment diversity in arthropods. Crustaceans exhibit impressive diversity and specialization in their ...
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Therapeutic gene modulation

Therapeutic gene modulation refers to the practice of altering the expression of a gene at one of various stages, with a view to alleviate some form of ailment. It differs from gene therapy in that gene modulation seeks to alter the expression of an endogenous gene (perhaps through the introduction of a gene encoding a novel modulatory protein) whereas gene therapy concerns the introduction of a gene whose product aids the recipient directly.Modulation of gene expression can be mediated at the level of transcription by DNA-binding agents (which may be artificial transcription factors), small molecules, or synthetic oligonucleotides. It may also be mediated post-transcriptionally through RNA interference.
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