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PCR-assay of intragenic DNA lesions induced by ionizing radiation
PCR-assay of intragenic DNA lesions induced by ionizing radiation

... observed; To detect the intragenic distribution of different DNA alterations relative to the exon-intron structure of the gene under study ...
Ch 19 Genomics
Ch 19 Genomics

... Those “genes” that are green from “normal” tissue genes ...
Basics in Genetics
Basics in Genetics

... Null mutation= makes no protein or totally non-functional protein. Weak or Hypomorphic mutation= makes protein that retains some but not all function. Loss of function mutation vs. Gain of function mutation c. One gene has different alleles. Normal allele = wild type. Different changes in gene seque ...
Unit 6 Part 2 Notes Jan 16 2012
Unit 6 Part 2 Notes Jan 16 2012

... interest to a vector like bacteria or a virus which will incorporate in all future DNA) • reproductive cloning (transfer of nuclear material from a somatic cell of one organism to an egg of another that has had its nucleus removed, resulting in an offspring like the ...
Gene Therapy: Using Viral and Non-Viral Vectors to Deliver Therapeutic Genes to the Human Body
Gene Therapy: Using Viral and Non-Viral Vectors to Deliver Therapeutic Genes to the Human Body

... AAV are non-pathogenic human singlestrand DNA parvoviruses Need helper adenovirus to proliferate Insert DNA in specific location on chromosome 19 Difficult to produce, and only 4.7kb long However, non-pathogenic, so there is no immune response to the virus ...
Science 9 Unit Test on Reproduction Outline Key Vocabulary
Science 9 Unit Test on Reproduction Outline Key Vocabulary

... Where DNA is stored and what it is made up of How proteins are produced in cells Types of gene mutations What is gene therapy? Checkpoints in the cell cycle Differences between asexual and sexual reproduction/examples/advantages/disadvantage Difference between internal and external fertilization Zyg ...
NAME CH11 In class assignment Due 2/18/14 Across 1. Initials of
NAME CH11 In class assignment Due 2/18/14 Across 1. Initials of

... for these single stranded sections is: a) “single ends” b) “lonely ends” c) “sticky ends” d) “fragmented ends” 3) In order to produce a transgenic animal, DNA must be injected into the __________________. a) unfertilized egg b) unfertilized sperm c) zygote (fertilized egg) d) fetus during the 3rd tr ...
Journey Into dna
Journey Into dna

... Human body: How many cells does the human body contain? What is the only type of cell in the human body that contains no nucleus and therefore no nuclear DNA? Intestines: Is the DNA code from cell to cell in the human body the same? Cells: ...
DNA Replication
DNA Replication

... • Nitrogenous base ...
EXPLORE THE ISSUE BEING INVESTIGATED
EXPLORE THE ISSUE BEING INVESTIGATED

... 2. Regulating the target gene. Two of LHX3’s domains mediate protein-protein interactions once the transcription factor has attached to the DNA. By having particular shapes that bump into the regulatory proteins Pit-1 and NLI in just such a way, these domains influence what happens as the polymerase ...
amp R - Fort Bend ISD
amp R - Fort Bend ISD

... hopefully get the best of both buffalo and a cow to get a beefalo donkey and a horse 2. inbreeding-breeding of organisms with similar traits makes organisms more homozygous and allows mutant genes to get together to produce mutant organisms B. Polyploidy-having an extra set of chromosomes; only occu ...
Fill-in-Notes - Pearland ISD
Fill-in-Notes - Pearland ISD

... Applied Genetics: is the _________; of the hereditary characteristics of an organism to improve or create specific traits in ______________. Selective breeding: directed breeding to produce plant and animal with _____________ Ex: breeding plants to produce larger fruits/vegetable Inbreeding: ______ ...
Analysis of Genomes
Analysis of Genomes

... 1. Why? a. ...
Of Traits and Proteins:
Of Traits and Proteins:

... What’s in Your Potato? Unlike bacteria, which are single-cell organisms, plants are made up of many different cells. How can a gene be inserted into a multi-cellular plant to give it a new trait? Inserting a gene into a plant involves the same principle as inserting a gene into bacteria: DNA contain ...
Cancer Research Project
Cancer Research Project

... 5. What are the symptoms and physiological problems of this cancer? 6. What signaling pathway is this gene involved in? 7. What current treatments are available or under investigation regarding this type of oncogene (or the cancer it causes). 4. Along with the answers to these questions, you should ...
Epigenetics Glossary FINAL
Epigenetics Glossary FINAL

... DNA Methylation: The addition of a methyl (CH¬3) group to the DNA. It usually occur at DNA cytosine nucleotides followed by guanosine (C-phosphate-G, CpG) and represses gene expression. DNA methyltransferases (DNMTs). Enzymes that catalyze the transfer of a methyl group to DNA from Sadenosylmethioni ...
Gene Section AF15q14 (ALL1 fused gene from 15q14) in Oncology and Haematology
Gene Section AF15q14 (ALL1 fused gene from 15q14) in Oncology and Haematology

... t(11;15)(q23;q14)/acute non lymphocytic leukemia (ANLL) --> MLL/AF15q14 ...
Chromosome Structure 1 - Dr. Kordula
Chromosome Structure 1 - Dr. Kordula

... ubiquitinated. Such adducts will influence the affinity of the nucleosome for  non­histone proteins involved in packaging and gene expression.  Transcriptional activity typically involves shuffling and sliding of  nucleosomes to make way for the transcription apparatus. However, recently it  has bee ...
DNA_Project - Berkeley Cosmology Group
DNA_Project - Berkeley Cosmology Group

... from phosphate, a sugar, and one of four nitrogenous bases. The four nitrogenous bases are adenine, thymine, cytosine, and guanine. Based on this cytosine bonds with guanine, and thymine binds with guanine to form bonds between the nucleotides thus creating a strand of DNA. DNA is used in a cell to ...
Hfr cells
Hfr cells

... promoters, operators, effectors, inducers, repressors and co-repressors in your answer. Discuss the levels of bacterial control of gene expression, paying particular attention to post-translational and transcriptional control, as discussed in lecture. What is quorum sensing? How does it relate to ge ...
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notes

... • Usually, have to find the gene by genetic mapping - use affected families and DNA polymorphisms all over genome - analyse linkage ...
BIO 220 Chapter 8 lecture outline Vocabulary Central dogma of
BIO 220 Chapter 8 lecture outline Vocabulary Central dogma of

... 1. Be able to define all of the vocabulary used in lecture. 2. What is the central dogma of biology? Who proposed this theory? 3. What is the difference between the terms genotype and phenotype? Are bacteria typically diploid or haploid? What do diploid and haploid mean? 4. How many chromosomes does ...
13.3- The Human Genome
13.3- The Human Genome

... “The results of the Human Genome Project included a better understanding of the roles genes play in the human body. Scientists learned that there were fewer genes than originally believed that make up the human genome.They were able to learn that all genes do not have one specific role, as was previ ...
DNA Biology - De Anza College
DNA Biology - De Anza College

... • Double – stranded, twisted ladder • Rungs are paired nucleotides • Complementary pairing: hydrogen bonds – A pairs with T – G pairs with C ...
Transcription Control in Eukaryotes - University of Arizona | Ecology
Transcription Control in Eukaryotes - University of Arizona | Ecology

... recruited to the promoter and binds RNA polymerase holoenzyme (polymerase plus other proteins) . 4. RNA polymerase holoenzyme binds to promoter and begins transcription. ...
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Therapeutic gene modulation

Therapeutic gene modulation refers to the practice of altering the expression of a gene at one of various stages, with a view to alleviate some form of ailment. It differs from gene therapy in that gene modulation seeks to alter the expression of an endogenous gene (perhaps through the introduction of a gene encoding a novel modulatory protein) whereas gene therapy concerns the introduction of a gene whose product aids the recipient directly.Modulation of gene expression can be mediated at the level of transcription by DNA-binding agents (which may be artificial transcription factors), small molecules, or synthetic oligonucleotides. It may also be mediated post-transcriptionally through RNA interference.
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