Access Presentation
... – p53 exists as a homotetramer: assembly of four identical polypeptide subunits ...
... – p53 exists as a homotetramer: assembly of four identical polypeptide subunits ...
1 - Test Bank Corp
... As of 2004, Human Genome Project researchers had mapped the genome to a point of being 99% completed, and the number of gaps in the human genome had decreased from ___ to ___. A) 25,000, 20,000 B) 150,000, 25,000 C) 25,000, 341 D) 150,000, 341 Ans: d ...
... As of 2004, Human Genome Project researchers had mapped the genome to a point of being 99% completed, and the number of gaps in the human genome had decreased from ___ to ___. A) 25,000, 20,000 B) 150,000, 25,000 C) 25,000, 341 D) 150,000, 341 Ans: d ...
Student Handout
... teosinte and maize look like very different plants. It seemed unlikely that teosinte would give rise to maize within the 10,000 years or so that humans had been growing crops, because the process would involve changes in many genes—too many to occur in this time span. Dr. Beadle’s experiment set out ...
... teosinte and maize look like very different plants. It seemed unlikely that teosinte would give rise to maize within the 10,000 years or so that humans had been growing crops, because the process would involve changes in many genes—too many to occur in this time span. Dr. Beadle’s experiment set out ...
A novel role for the floral homeotic gene APETALA2
... by SEM analysis revealed that the replum was conspicuously wider than in wild type (Fig. 2M,N), even at early stages of ...
... by SEM analysis revealed that the replum was conspicuously wider than in wild type (Fig. 2M,N), even at early stages of ...
PPT
... Survey multiple European-Americans in Utah: >99% Thr. Survey multiple Han Chinese in Beijing: >93% Ala. Survey multiple Japanese in Tokyo: >93% Ala. Survey multiple Yoruba in Ibadan, Nigeria: >93% Ala. ...
... Survey multiple European-Americans in Utah: >99% Thr. Survey multiple Han Chinese in Beijing: >93% Ala. Survey multiple Japanese in Tokyo: >93% Ala. Survey multiple Yoruba in Ibadan, Nigeria: >93% Ala. ...
Rapid Diversification of RNase A Superfamily Ribonucleases from
... the five novel sequences (rc-203, rc-204, rc-208, rc-212, and rc-218), the previously identified rc-L1 and rcRNase (rc-RN), and the single sequence isolated from the species R. japonica (rj-lec). Subcluster B includes the shorter (105–106 amino acid) sequences: rc-02, rc-03, rc-04, rc-06, rp-onc, an ...
... the five novel sequences (rc-203, rc-204, rc-208, rc-212, and rc-218), the previously identified rc-L1 and rcRNase (rc-RN), and the single sequence isolated from the species R. japonica (rj-lec). Subcluster B includes the shorter (105–106 amino acid) sequences: rc-02, rc-03, rc-04, rc-06, rp-onc, an ...
The EGF-CFC Protein One-Eyed Pinhead Is Essential for
... (A2). (A3, A4, B3, and B4) Expression of pax6 at 1S in forebrain and presumptive eye fields and hindbrain (arrow). Bilateral pax6 expression domains are fused in MZoep mutants (arrowhead). (A5, A6, B5, and B6) Expression of krox20 at 2S in rhombomeres 3 and 5. Note the vegetal gap posterior to rhomb ...
... (A2). (A3, A4, B3, and B4) Expression of pax6 at 1S in forebrain and presumptive eye fields and hindbrain (arrow). Bilateral pax6 expression domains are fused in MZoep mutants (arrowhead). (A5, A6, B5, and B6) Expression of krox20 at 2S in rhombomeres 3 and 5. Note the vegetal gap posterior to rhomb ...
Relative Paucity of Genes Causing Inviability in Hybrids
... alleles of the white locus. Females from such strains were crossed to D. simulans white males. Females from X-chromosome deficiency stocks carrying FM6 (which contains the dominant mutation Bar) were crossed to wild-type D. simulans males from the Florida City strain (see below), and Bar vs. non-Bar ...
... alleles of the white locus. Females from such strains were crossed to D. simulans white males. Females from X-chromosome deficiency stocks carrying FM6 (which contains the dominant mutation Bar) were crossed to wild-type D. simulans males from the Florida City strain (see below), and Bar vs. non-Bar ...
III. Linkage
... the X with the gene for orange color condenses, the ‘non-orange’ allele allows genes for other colors at other loci to be expressed (black, brown, ‘blue’). The X that is inactivated is determined randomly, early in development. This inactivation is imprinted on that X, such that descendants of those ...
... the X with the gene for orange color condenses, the ‘non-orange’ allele allows genes for other colors at other loci to be expressed (black, brown, ‘blue’). The X that is inactivated is determined randomly, early in development. This inactivation is imprinted on that X, such that descendants of those ...
Emended description of the order Chlamydiales, proposal of
... The current taxonomic classification of Chlamydia is based on limited phenotypic, morphologic and genetic criteria. This classification does not take into account recent analysis of the ribosomal operon or recently identified obligately intracellular organisms that have a chlamydia-like developmenta ...
... The current taxonomic classification of Chlamydia is based on limited phenotypic, morphologic and genetic criteria. This classification does not take into account recent analysis of the ribosomal operon or recently identified obligately intracellular organisms that have a chlamydia-like developmenta ...
Multilevel functional and structural defects induced by two
... Point mutations in hmtRNAs (human mitochondrial tRNAs) can cause various disorders, such as CPEO (chronic progressive external ophthalmoplegia) and MM (mitochondrial myopathy). Mitochondrial tRNALeu , especially the UUR codon isoacceptor, is recognized as a hot spot for pathogenic mtDNA point mutati ...
... Point mutations in hmtRNAs (human mitochondrial tRNAs) can cause various disorders, such as CPEO (chronic progressive external ophthalmoplegia) and MM (mitochondrial myopathy). Mitochondrial tRNALeu , especially the UUR codon isoacceptor, is recognized as a hot spot for pathogenic mtDNA point mutati ...
Water SA
... The genus Legionella comprises more than 40 species and 64 serogroups with approximately half of those species associated with human diseases. Legionella pneumophila Serogroup 1 is the most common pathogenic species and is responsible for up to 80% of legionellosis cases in the world. Legionella lev ...
... The genus Legionella comprises more than 40 species and 64 serogroups with approximately half of those species associated with human diseases. Legionella pneumophila Serogroup 1 is the most common pathogenic species and is responsible for up to 80% of legionellosis cases in the world. Legionella lev ...
Defining the Schistosoma haematobium kinome enables the
... to control this disease by mass treatment, the possibility of praziquantel resistance developing is a serious concern11,12. Thus, there is a need for sustained research toward developing alternative chemotherapeutic compounds against schistosomiasis. Recent research efforts to identify new molecular ...
... to control this disease by mass treatment, the possibility of praziquantel resistance developing is a serious concern11,12. Thus, there is a need for sustained research toward developing alternative chemotherapeutic compounds against schistosomiasis. Recent research efforts to identify new molecular ...
REVIEWS
... early ancestry. This, in turn, would imply that it has been lost in other Drosophila family members, Caenorhabditis elegans and urochordates. Alternatively, the SNAG domain might have been added independently in each of the different species. The availability of complete coding sequences from other ...
... early ancestry. This, in turn, would imply that it has been lost in other Drosophila family members, Caenorhabditis elegans and urochordates. Alternatively, the SNAG domain might have been added independently in each of the different species. The availability of complete coding sequences from other ...
Novel pathogen-specific primers for the detection of Agrobacterium
... crown gall (BURR et al. 1998). Besides A. vitis, Agrobacterium tumefaciens may also occur on grapevines as causative agent of crown gall disease (SZEGEDI et al. 2005). The polymerase chain reaction (PCR) has widely been used to test for the presence of various plant pathogens to select clean plant m ...
... crown gall (BURR et al. 1998). Besides A. vitis, Agrobacterium tumefaciens may also occur on grapevines as causative agent of crown gall disease (SZEGEDI et al. 2005). The polymerase chain reaction (PCR) has widely been used to test for the presence of various plant pathogens to select clean plant m ...
Hypoxia in skeletal muscles: from physiology to gene expression
... (JNK) under hypoxia [46]. Besides NO, increases in the activity of anti-oxidant enzymes such as superoxide dismutase (SOD) which removes superoxide and catalase (CAT) which removes hydrogen peroxide as well as pro-oxidant enzymes such as NADPH oxidase are also reported [47]. Thus, the redox system i ...
... (JNK) under hypoxia [46]. Besides NO, increases in the activity of anti-oxidant enzymes such as superoxide dismutase (SOD) which removes superoxide and catalase (CAT) which removes hydrogen peroxide as well as pro-oxidant enzymes such as NADPH oxidase are also reported [47]. Thus, the redox system i ...
The Genetics of CFTR: Genotype – Phenotype Relationship
... tissue-specific manner. In class III are included mutations leading to defective regulation that impair channel opening. Although the CFTR protein is able to reach the apical membrane, it is not properly activated by ATP or cAMP. The effect is a decrease or absence of functional CFTR protein. In cla ...
... tissue-specific manner. In class III are included mutations leading to defective regulation that impair channel opening. Although the CFTR protein is able to reach the apical membrane, it is not properly activated by ATP or cAMP. The effect is a decrease or absence of functional CFTR protein. In cla ...
DNA METHODS FOR HLA TYPING A WORKBOOK FOR - ASHI-U
... Hematopoietic stem cells found in the bone marrow differentiate to become blood cells. These cells play important roles in fighting infection (white blood cells or lymphocytes), in transporting oxygen to the tissues (red blood cells), and in causing blood clotting (platelets). Certain types of cance ...
... Hematopoietic stem cells found in the bone marrow differentiate to become blood cells. These cells play important roles in fighting infection (white blood cells or lymphocytes), in transporting oxygen to the tissues (red blood cells), and in causing blood clotting (platelets). Certain types of cance ...
Genome-Wide Association Mapping Reveals Novel QTL for
... made it feasible to genotype a large collection of germplasm lines with thousands of SNP markers. As a result, the GWAS approach, based on the principle of linkage disequilibrium (LD), has been effectively used to exploit existing allelic diversity for traits of agronomic importance. Compared with b ...
... made it feasible to genotype a large collection of germplasm lines with thousands of SNP markers. As a result, the GWAS approach, based on the principle of linkage disequilibrium (LD), has been effectively used to exploit existing allelic diversity for traits of agronomic importance. Compared with b ...
SPT4, a gene important for tr
... Gaber), yielding pJF101. The URA3 gene was inserted at the unique XhoI site in the remaining portion of the Tn5, resulting in pJF104. The EcoRI fragment containing spt4A 1 : : URA3 was purified and used to transform strain FY120 to Ura + (Rothstein 1983), creating strain FY243. Southern hybridizatio ...
... Gaber), yielding pJF101. The URA3 gene was inserted at the unique XhoI site in the remaining portion of the Tn5, resulting in pJF104. The EcoRI fragment containing spt4A 1 : : URA3 was purified and used to transform strain FY120 to Ura + (Rothstein 1983), creating strain FY243. Southern hybridizatio ...
Implementing array comparative genomic hybridization in male
... Some work has been done to identify additional candidate genes via animal model approaches, but there have been several limitations to identify novel genes associated with male infertility. These limitations include inappropriate controls, single gene analysis, lack of family pedigrees to corroborat ...
... Some work has been done to identify additional candidate genes via animal model approaches, but there have been several limitations to identify novel genes associated with male infertility. These limitations include inappropriate controls, single gene analysis, lack of family pedigrees to corroborat ...
no isthmus and pax2.1 in zebrafish tubulogenesis
... cells of the nephron primordium between 30 and 32 hpf and is the earliest known marker of tubule differentiation and nephron patterning (Fig. 4A; refer to Fig. 3 for details on plane of section). In the hypomorphic noitb21 allele, pax2.1 mRNA expression can be detected in several tissues during phar ...
... cells of the nephron primordium between 30 and 32 hpf and is the earliest known marker of tubule differentiation and nephron patterning (Fig. 4A; refer to Fig. 3 for details on plane of section). In the hypomorphic noitb21 allele, pax2.1 mRNA expression can be detected in several tissues during phar ...
trigger - Bioconductor
... Imports qvalue, methods, graphics, sva Description This R package provides tools for the statistical analysis of integrative genomic data that involve some combination of: genotypes, high-dimensional intermediate traits (e.g., gene expression, protein abundance), and higher-order traits (phenotypes) ...
... Imports qvalue, methods, graphics, sva Description This R package provides tools for the statistical analysis of integrative genomic data that involve some combination of: genotypes, high-dimensional intermediate traits (e.g., gene expression, protein abundance), and higher-order traits (phenotypes) ...
RNA-Seq
RNA-seq (RNA sequencing), also called whole transcriptome shotgun sequencing (WTSS), is a technology that uses the capabilities of next-generation sequencing to reveal a snapshot of RNA presence and quantity from a genome at a given moment in time.