DANIELE GHEZZI Matr. N°. 708361 Identification and
... Each human cell has thousands of mitochondria and within each single mitochondrion are present multiple copies (2 to 10) of mtDNA. Usually all these copies are identical, a status known as homoplasmy. However it is possible that errors occur during replication or repair of mtDNA, leading to the form ...
... Each human cell has thousands of mitochondria and within each single mitochondrion are present multiple copies (2 to 10) of mtDNA. Usually all these copies are identical, a status known as homoplasmy. However it is possible that errors occur during replication or repair of mtDNA, leading to the form ...
A newly discovered Anaerococcus strain responsible for axillary
... in the axillary region but was unable to establish any correlation. In contrast, Hasegawa et al. (2004) reported that more sulfurous odor was derived from sweat incubated under anaerobic conditions rather than under aerobic conditions, suggesting that the anaerobic bacteria in sweat contribute to ax ...
... in the axillary region but was unable to establish any correlation. In contrast, Hasegawa et al. (2004) reported that more sulfurous odor was derived from sweat incubated under anaerobic conditions rather than under aerobic conditions, suggesting that the anaerobic bacteria in sweat contribute to ax ...
Introduction of the AmpliChip CYP450 Test to a prospective cohort study
... Ethical approval was obtained from the Research Ethics Committee, Faculty of Health Science, University of Pretoria (Approval numbers: Cohort 1 - 102/2005 and Cohort 2 - S132/2009) and the study was conducted in accordance with the Declaration of Helsinki, using GCP guidelines. All participating vol ...
... Ethical approval was obtained from the Research Ethics Committee, Faculty of Health Science, University of Pretoria (Approval numbers: Cohort 1 - 102/2005 and Cohort 2 - S132/2009) and the study was conducted in accordance with the Declaration of Helsinki, using GCP guidelines. All participating vol ...
Simple identification of dominant p53 mutants by
... impaired degradation model provides a satisfactory explanation for the high level p53 expression seen in tumours (5,6), it does not rule out the possibility that a selective growth advantage may be conferred by mutated p53 proteins, either because dominant inhibition of wild-type protein could facil ...
... impaired degradation model provides a satisfactory explanation for the high level p53 expression seen in tumours (5,6), it does not rule out the possibility that a selective growth advantage may be conferred by mutated p53 proteins, either because dominant inhibition of wild-type protein could facil ...
709_2010_211_MOESM2_ESM - Springer Static Content Server
... ARABIDOPSIS HISTIDINE PHOSPHOTRANSFER PROTEIN 6: AHP6 lacks the conserved histidine residue (Asn83 in AHP6b), which is required for phosphotransfer, present in the other AHPs. AHP6 does not appear to have phosphotransfer activity. Acts as an inhibitor of cytokinin signalling by interacting with the ...
... ARABIDOPSIS HISTIDINE PHOSPHOTRANSFER PROTEIN 6: AHP6 lacks the conserved histidine residue (Asn83 in AHP6b), which is required for phosphotransfer, present in the other AHPs. AHP6 does not appear to have phosphotransfer activity. Acts as an inhibitor of cytokinin signalling by interacting with the ...
Cells: building blocks of living organisms
... Genome of multicellular animals (including human) The human genome has two parts: Nuclear genome: Consists of 23 pairs of chromosomes; for a total of 24 distinct linear molecules (22 autosomes and 2 sex chromosomes X and Y). The shortest chromosome consists of approximately 50 million nucleotides. ...
... Genome of multicellular animals (including human) The human genome has two parts: Nuclear genome: Consists of 23 pairs of chromosomes; for a total of 24 distinct linear molecules (22 autosomes and 2 sex chromosomes X and Y). The shortest chromosome consists of approximately 50 million nucleotides. ...
Inference of natural selection on quantitative traits
... Genes are the central elements of the genome. Genes serve as the blueprint for proteins, which are biomolecules that perform a vast number of functions in an organism. The coding region of a gene is marked by a characteristic starting sequence, also called promoter, and is read off by a protein call ...
... Genes are the central elements of the genome. Genes serve as the blueprint for proteins, which are biomolecules that perform a vast number of functions in an organism. The coding region of a gene is marked by a characteristic starting sequence, also called promoter, and is read off by a protein call ...
Consulta: subjectFacets:"16S rRNA" Registros recuperados: 43
... A reverse transcriptase - polymerase chain reaction based assay for Borrelia species detection in ticks was developed. The method was based on amplification of 552 nucleotide bases long sequence of 16S rRNA, targeted by Borrelia specific primers. In the present study, total RNA extracted from Ixodes ...
... A reverse transcriptase - polymerase chain reaction based assay for Borrelia species detection in ticks was developed. The method was based on amplification of 552 nucleotide bases long sequence of 16S rRNA, targeted by Borrelia specific primers. In the present study, total RNA extracted from Ixodes ...
Visceral endoderm-restricted translation of Otx1
... still off, and, at a later stage, Otx1 is required primarily in the dorsal telencephalon where Otx2 is not transcribed. Therefore, these findings support two hypotheses: (i) Otx1 and Otx2 functional properties might largely overlap and differences in their temporal and spatial transcriptional contro ...
... still off, and, at a later stage, Otx1 is required primarily in the dorsal telencephalon where Otx2 is not transcribed. Therefore, these findings support two hypotheses: (i) Otx1 and Otx2 functional properties might largely overlap and differences in their temporal and spatial transcriptional contro ...
Agilent 2100 Bioanalyzer User`s Guide for Molecular Assays
... 10 Follow the cleaning protocol for the particular assay you were running as described in the appropriate Reagent Kit Guide. 11 To view results for individual wells as data is acquired or after the run is finished, click a well in the chip icon, a single well on the large multiwell display, or a la ...
... 10 Follow the cleaning protocol for the particular assay you were running as described in the appropriate Reagent Kit Guide. 11 To view results for individual wells as data is acquired or after the run is finished, click a well in the chip icon, a single well on the large multiwell display, or a la ...
The Role of Carbohydrate Response Element Binding Protein in
... mechanisms underlying intestinal and hepatic fructose metabolism will be beneficial for understanding the pathogenesis of not only obesity-related diseases, but also fructose malabsorption. We have analyzed the role of carbohydrate response element binding protein (ChREBP) in the pathogenesis of met ...
... mechanisms underlying intestinal and hepatic fructose metabolism will be beneficial for understanding the pathogenesis of not only obesity-related diseases, but also fructose malabsorption. We have analyzed the role of carbohydrate response element binding protein (ChREBP) in the pathogenesis of met ...
PhyPA: Phylogenetic method with pairwise sequence alignment
... I have developed and implemented a phylogenetic reconstruction method based on PSA only (named PhyPA for Phylogenetics by Pairwise Alignment) for highly diverged sequences (One should use likelihood-based method whenever sequences are not highly diverged and reliable MSA can be obtained). I evaluate ...
... I have developed and implemented a phylogenetic reconstruction method based on PSA only (named PhyPA for Phylogenetics by Pairwise Alignment) for highly diverged sequences (One should use likelihood-based method whenever sequences are not highly diverged and reliable MSA can be obtained). I evaluate ...
AngelasPPT
... MOI for 1 hour (to allow one round of infection) Why at high MOI? So each cell can be infected by both mutants am2- ...
... MOI for 1 hour (to allow one round of infection) Why at high MOI? So each cell can be infected by both mutants am2- ...
Adenomatous Polyp
... adenomas to carcinomas. In this scheme, mutations of the APC gene (resulting in homozygous loss of this tumor suppressor gene) are believed to occur first. (Patients with familial adenomatous polyposis syndrome are born with loss of one copy of the APC gene in all somatic cells.) As the adenomas enl ...
... adenomas to carcinomas. In this scheme, mutations of the APC gene (resulting in homozygous loss of this tumor suppressor gene) are believed to occur first. (Patients with familial adenomatous polyposis syndrome are born with loss of one copy of the APC gene in all somatic cells.) As the adenomas enl ...
Nature inspired platforms for production of acetyl
... toughest times of my graduate career. I could not have asked for a better advisor. I would love to extend my sincere appreciation and gratitude to the members of my thesis committee members: Dr. Michelle Chang, Dr. Jasper Rine, and Dr. Carolyn Bertozzi for their guidance during my study. I would lik ...
... toughest times of my graduate career. I could not have asked for a better advisor. I would love to extend my sincere appreciation and gratitude to the members of my thesis committee members: Dr. Michelle Chang, Dr. Jasper Rine, and Dr. Carolyn Bertozzi for their guidance during my study. I would lik ...
1 RUNNING TITLE Diversity and selection of
... encodes a YABBY transcription factor and down regulation of the gene is caused by a large insertion in the first intron (estimated to be 6 to 8 kb) resulting in fruits with high locule number (Cong et al., 2008). The molecular nature of LC was recently identified (Muños et al., unpublished data). T ...
... encodes a YABBY transcription factor and down regulation of the gene is caused by a large insertion in the first intron (estimated to be 6 to 8 kb) resulting in fruits with high locule number (Cong et al., 2008). The molecular nature of LC was recently identified (Muños et al., unpublished data). T ...
Document
... and its mutant phenotype we need to study the gene at multiple levels: Genetics- mutant gene- mutant phenotype Now what? Genetics will relate specific mutation to specific phenotype It usually provides No Information about how the protein generates the phenotype For p53 We would like to know The nuc ...
... and its mutant phenotype we need to study the gene at multiple levels: Genetics- mutant gene- mutant phenotype Now what? Genetics will relate specific mutation to specific phenotype It usually provides No Information about how the protein generates the phenotype For p53 We would like to know The nuc ...
From RNA to protein
... Genes to Phenotypes "A set of genes represents the individual components of the biological system under scrutiny" Modifications of the "3:1 F2 monohybrid ratio" and gene interactions are the rules rather than the exceptions" ...
... Genes to Phenotypes "A set of genes represents the individual components of the biological system under scrutiny" Modifications of the "3:1 F2 monohybrid ratio" and gene interactions are the rules rather than the exceptions" ...
Nucleotide sequence and structural organization of
... The study of small plasmids from a variety of bacteria has recently become a focus of research interest and in several cases this work has led to the development of families of vectors designed for specific purposes. The genetic organization and mode of replication of a number of small cryptic plasm ...
... The study of small plasmids from a variety of bacteria has recently become a focus of research interest and in several cases this work has led to the development of families of vectors designed for specific purposes. The genetic organization and mode of replication of a number of small cryptic plasm ...
Transvection Is Common Throughout the Drosophila
... et al. 2004). These lineages are further subdivided into hemilineages based on Notch activity (Truman et al. 2010), and these hemilineages can also be recognized by their neuron position and morphology. To have a genetic handle on these populations of neurons, we have been taking advantage of a rece ...
... et al. 2004). These lineages are further subdivided into hemilineages based on Notch activity (Truman et al. 2010), and these hemilineages can also be recognized by their neuron position and morphology. To have a genetic handle on these populations of neurons, we have been taking advantage of a rece ...
oto`s role in head and trunk development
... 5086 J. S. Zoltewicz and others requirement that is consistent with other recent insights into the regulation of mammalian anterior development. The first obvious sign of anteroposterior (AP) pattern in the mouse embryo is provided by the formation of the primitive streak. Molecular studies have sh ...
... 5086 J. S. Zoltewicz and others requirement that is consistent with other recent insights into the regulation of mammalian anterior development. The first obvious sign of anteroposterior (AP) pattern in the mouse embryo is provided by the formation of the primitive streak. Molecular studies have sh ...
CIRCADIAN RHYTHMS IN PLANTS C Robertson McClung
... component to this regulation in several angiosperms (33, 116). Typical reporters are unsuitable for circadian studies. Even though mRNA abundance oscillates in response to clock-gated transcription, the reporter activity (e.g. β-glucuronidase or chloramphenicol acetyltransferase) is too stable to al ...
... component to this regulation in several angiosperms (33, 116). Typical reporters are unsuitable for circadian studies. Even though mRNA abundance oscillates in response to clock-gated transcription, the reporter activity (e.g. β-glucuronidase or chloramphenicol acetyltransferase) is too stable to al ...
Slayt 1
... * No association was noted between a history of endometriosis and borderline ovarian cancer. * History of endometriosis was associated with an increased risk of invasive epithelial ovarian cancer. * 2-3 fold increase in the risk of clear-cell, low-grade serous, and endometrioid invasive ovarian canc ...
... * No association was noted between a history of endometriosis and borderline ovarian cancer. * History of endometriosis was associated with an increased risk of invasive epithelial ovarian cancer. * 2-3 fold increase in the risk of clear-cell, low-grade serous, and endometrioid invasive ovarian canc ...
Chromosomal Aberration of the 11q23 Locus in Acute Leukemia
... adult ALL, the overall incidence of 11q23+/MLL+ is reported to be around 3% to 7%,11 but in pro-B-cell ALL, it accounts for more than 30% of chromosomal aberrations.12,13 While t(4;11) ALL has an established dismal prognosis, the clinical outcome of 11q23+/MLL+ AML is more heterogeneous. 14-16 The M ...
... adult ALL, the overall incidence of 11q23+/MLL+ is reported to be around 3% to 7%,11 but in pro-B-cell ALL, it accounts for more than 30% of chromosomal aberrations.12,13 While t(4;11) ALL has an established dismal prognosis, the clinical outcome of 11q23+/MLL+ AML is more heterogeneous. 14-16 The M ...
RNA-Seq
RNA-seq (RNA sequencing), also called whole transcriptome shotgun sequencing (WTSS), is a technology that uses the capabilities of next-generation sequencing to reveal a snapshot of RNA presence and quantity from a genome at a given moment in time.