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Sensing DNA? Aim for the cytoplasm in Systemic Lupus
Sensing DNA? Aim for the cytoplasm in Systemic Lupus

... Erythematosus (SLE) with phenotypic features of nephritis, autoantibody production and death2. A bioinformatic approach that includes comparative sequence analysis has been employed to investigate the homology and disparity in the genomic architecture at this locus. ...
Transcription, RNA Processing, and
Transcription, RNA Processing, and

... In eukaryotes, mRNA is initially transcribed as precursor mRNA (“pre-mRNA”). This is part of a transcript called heterogeneous nuclear RNA (hnRNA); the terms hnRNA and premRNA are sometimes used interchangably. Almost all eukaryotic genes contain introns: noncoding regions that must be removed from ...
Molecular Biology 101
Molecular Biology 101

... for some genes the end product is RNA! –  ribosomal RNA (rRNA), which includes major constituents of ribosomes! –  transfer RNAs (tRNAs), which carry amino acids to ribosomes! –  micro RNAs (miRNAs), which play an important regulatory role in various plants and animals! ...
epigenomics - IES Valldemossa
epigenomics - IES Valldemossa

... Fragile X Syndrome is caused by an expanded CGG trinucleotide repeat in the Fragile X Mental Retardation (FMR1) gene leading to epigenetic silencing (by methylation) and loss of expression of the Fragile X Mental Retardation Protein (FMRP). ...
Let-7 is - University of Colorado-MCDB
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... • Amino acid sequences of D. melanogaster bHLH - PAS and the tblastn search tool were employed to find the presumed location of Met-receptor gene in the dragonfly genome • Samtools were used to retrieve the gene region (~7000 bp) • Python script was employed to find ORFs and stops • Some of the ORFs ...
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... Assigning Function to Proteins While 25000 genes have been identified in the human genome, relatively few have known functional annotation.  Determining the function of the protein can be done in several ways. ...
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... Recombination between linked genes comes about for what reason? A) Mutation on one homolog is different from that on the other homolog. B) Independent assortment sometimes fails because Mendel had not calculated appropriately. C) When genes are linked they always "travel" together at anaphase. D) C ...
Developmental Biology 8/e - Florida International University
Developmental Biology 8/e - Florida International University

... gene proteins Hunchback and Kruppel. - The Antennapedia gene is activated by particular levels of Hunchback. ...
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... Eigen’s theory is very useful in understanding the origin of life. The theory essentially shows that a selfreplicating molecule must be shorter (in terms of base pairs) than the reciprocal of the error rate for copying each base. It is thought that the first self-replicating molecule was an RNA (or ...
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Human Blood Type Genetics

... Many blood group antigens are indirect gene products. For example, A and B antigens are carbohydrates. Their genes produce proteins (enzymes) called transferases which transfer sugars from carrier molecules to acceptor molecules. Usually if a gene is present, its corresponding antigen will be presen ...
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13.4 Gene Regulation and Expression

... Eukaryotic Gene Regulation Transcription factors are DNA-binding proteins. They control the expression of genes in eukaryotes by binding DNA sequences in the regulatory regions. Gene promoters have multiple binding sites for transcription factors, each of which can influence transcription. Complex g ...
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RNA & Transcription

... mRNA processing: The newly synthesized RNA is called the primary RNA transcript (preRNA). It may average 200,000 nucleotides (the avg. for human cells is only 1000.) Studies show that RNA molecules undergo extensive processing before leaving the nucleus. ...
PPT NOTES_AP Biology Chapter 17 Notes
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... • Enzymes in the eukaryotic nucleus _________________ pre-mRNA before the genetic messages are dispatched to the cytoplasm • During RNA processing, both ___________ of the primary transcript are usually altered • Also, usually some interior parts of the molecule are ________________, and the other p ...
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Leukaemia Section t(3;11)(q25;q23) Atlas of Genetics and Cytogenetics in Oncology and Haematology

... Protein 431 kDa; contains two DNA binding motifs (a AT hook, and Zinc fingers), a DNA methyl transferase motif, a bromodomain; transcriptional regulatory factor; nuclear localisation. ...
Population Genetics
Population Genetics

... 1. Mountains, canyons, rivers, highways, climate and even other organisms can serve as barriers for various kinds of plants and animals. 2. When a population becomes divided by a barrier, interbreeding cannot occur. Genes will not flow between them and their gene pools may diverge. ...
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Intro to Genetics Webquest

... 23) A dog fetching a bone is an example of what kind of trait. 24) Scientists describe the set of information for each form of a trait as an ...
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RNA-Seq



RNA-seq (RNA sequencing), also called whole transcriptome shotgun sequencing (WTSS), is a technology that uses the capabilities of next-generation sequencing to reveal a snapshot of RNA presence and quantity from a genome at a given moment in time.
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