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Document

... to the homeorrhetic (Waddington) rules of the networks themselves. The final step, from metabolism to phenotypes is, in turn, strongly affected by exterior signals transferred to genes through the cytoplasm, activating, inhibiting and modulating response-buffering batteries of genes specific to diff ...
Lecture#31 – Evolution and cis
Lecture#31 – Evolution and cis

... Pleiotropy - one gene has influence over multiple traits - the phenomenon of a single gene being responsible for a number of distinct and seemingly unrelated phenotypic effects. - Consequence: mutations in the gene’s protein coding sequence will have a simultaneous affect on multiple traits -> drast ...
Prokaryotic Gene Expression Mechanisms RNA Types of RNA Other
Prokaryotic Gene Expression Mechanisms RNA Types of RNA Other

... repressor for lacO to 2 x 1010, but the affinity for random DNA sequences remains the same. So the specificity of repressor for lacO drops 3 orders of magnitude (or 1000-fold). Under these conditions, you can calculate that less than 3% of the lacO sites should have repressor bound to them (when IPT ...
Law of Independent Assortment
Law of Independent Assortment

... Epistasis: One gene masks the expression of a different gene for a different trait Dominance: One allele masks the expression of another allele of the same gene ...
View Appendix 1
View Appendix 1

... Foster City, CA). The PCR products were analysed with a capillary electrophoresis sequencer (CEQ 8800; Beckman Coulter) according to the manufacturer's instructions. The genotypes were scored using the program FRAGMENT ANALYSIS supplied by Beckman Coulter. Linkage Analysis. All linkage analyses have ...
DNA, RNA, and Protein
DNA, RNA, and Protein

... mRNA docks on ribosome. Its 1st codon is AUG tRNA with met binds via its anticodon UAC. tRNA with its amino binds to 2nd codon. Ribosome detaches met from 1st tRNA. Peptide bond forms between met & 2nd amino acid. First tRNA exits the ribosome & 3rd tRNA enters. Elongation continues until reaches st ...
Big Idea 3B Study Guide
Big Idea 3B Study Guide

... Big Idea Study Guide 3B Living Systems Store Info Directions: Answer the questions below to aid you in your study of the Big Idea 3B test. ...
11.3 Other Patterns of Inheritance
11.3 Other Patterns of Inheritance

... • A genes that have more than two alleles is said to have multiple alleles • An individual has only two copies of each gene, but more than two exist in a population • EX: Rabbit fur color, human blood types ...
Jumping Genes - University of South Alabama
Jumping Genes - University of South Alabama

... transposons. In effect they are transposons which move via RNA intermediates that usually can leave the host cells and infect other cells. The integrated DNA form (provirus) of the retrovirus bears a marked similarity to a ...
DNA/RNA/Protein Questions
DNA/RNA/Protein Questions

... What are proteins made of? How is the "Genetic Code" read? What is a codon? What is a start codon? Stop codon? What does Translation mean? What organelle makes proteins? What role does tRNA play in making proteins? What is an "anticodon"? What structure is it on? How is mRNA used to make proteins. W ...
ASSOCIATION STUDIES ARTICLE
ASSOCIATION STUDIES ARTICLE

... meiotic division and retain a 4c DNA content. The cells maintain a large size but spermiogenesis takes place with an elongation of the head, a reduction of the cytoplasmic volume and the acquisition of several flagella as illustrated in the bottom panel of the electron microscope images (normal sper ...
Assessment Questions - Teach Genetics (Utah)
Assessment Questions - Teach Genetics (Utah)

... 3. Explain how cortisol and the GR protein work together in the brain to relax a rat pup. You may draw a diagram. 4. The rat nurturing example shows us how parental behavior can shape the behavior of their offspring on a biochemical level. Relate this to humans and think about the personal and socia ...
DNA Code problerm
DNA Code problerm

... B. instability of the DNA molecule C. the ability of the same tRNA anticodon to recognize different codons D. the high mutability of certain genes 9. If you wanted to block transcription of a group of functionally related genes in a prokaryote, you could place an obstacle A. upstream of both the pro ...
Downstream analysis of transcriptomic data
Downstream analysis of transcriptomic data

... Principal  Component  Analysis  (PCA)   •  Principal   component   analysis   (PCA)   reduces   the   dimensionality   of   the   data   while   retaining   most   of   the   variance  in  the  data  set.     •  It   accomplishes   this   redu ...
iplant collaborative
iplant collaborative

... • £2M BBSRC funded project with TGAC, Warwick, Nottingham and Liverpool- Funded as a capital investment • Putting the Iplant system on top of TGAC Hardware, providing community access • Work with the community to ensure take up of the system and develop resources around imaging, systems biology and ...
Central Dogma
Central Dogma

... • rRNA: functional building blocks of ribosomes (site of translation) ...
File
File

...  Amino Acid Chains (Proteins) are built to perform specific functions in the cell  In the cell, Proteins have numerous jobs: Control the rate of reactions Regulate cell processes Form bones and muscles Transport substances into or out of cells Help to fight disease ...
Protein Synthesis
Protein Synthesis

... to make proteins) ...
Study Guide for Understanding the Concept of Protein Synthesis
Study Guide for Understanding the Concept of Protein Synthesis

... Transfer RNA (tRNA) acts as a "taxi" by which the "escort" ribosomes take the amino acids and position them into place as Ribosomal RNA (rRNA). Step #5: Ribosomes: From the rRNA, the amino acids continue their journey within the cytoplasm, resting on "floating" ribosomes or on the Rough ER. These ri ...
Package `PoissonSeq`
Package `PoissonSeq`

... (1) trans: to tranform the data using the order transformation or not to transform it. default value: TRUE (2) npermu: number of permuations. default value: 100 (3) seed: random seed to generate the permutation indexes. default value: 10 (4) ct.sum: if the total number of reads of a gene across all ...
File
File

...  These rabbits and cats have a mutant allele for the coat color gene.  The enzyme encoded by the gene is inactive at temperatures above about 35°C.  The extremities are cooler than the main body (around 25°C), so the fur on these ...
26P PROCEEDINGS OF THE BIOCHEMICAL SOCIETY
26P PROCEEDINGS OF THE BIOCHEMICAL SOCIETY

... yields that may be obtained of partial fragments, say 50-100 residues long, isolated from them. For many large RNA species it may be possible to isolate such ...
Genetics 3 - MaxSkyFan
Genetics 3 - MaxSkyFan

... ribosome, it can be translated into a protein. • The ribosome (constructed of rRNA) grabs the mRNA and reads the molecule three nucleotide bases at a time. Each set of three nucleotides is called a codon. • Each codon codes for a specific amino acid, using a table. • For the exam, you should be able ...
Polymorphisms, SNPs and Alleles
Polymorphisms, SNPs and Alleles

... –  Genes  that  have  a  high  Non-­‐synonymous  /  Synonymous  ra:o.   –  Tend  to  be  things  like  surface  an:gens  that  the  organisms  use  to   escape  immune  detec:on.   –  Use  comparators  high  on  the  list  (have  more   ...
Gene regulation - Department of Plant Sciences
Gene regulation - Department of Plant Sciences

... • Basal transcription regulation – general transcription factors • Development • Response to intercellular signals • Response to environment • Cell cycle control ...
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RNA-Seq



RNA-seq (RNA sequencing), also called whole transcriptome shotgun sequencing (WTSS), is a technology that uses the capabilities of next-generation sequencing to reveal a snapshot of RNA presence and quantity from a genome at a given moment in time.
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