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ppt
ppt

... OAA, which form citrate Citrate in cytosol then to Ac CoA, malonyl CoA Fatty acid synthesis involve series 2-C additions from malonyl CoA to the w-C of Ac CoA onto FA synthase. Costs 2 NADPH and 1 ATP per cycle addition ...
Ch. 33 Synthesis of Fatty acids, Triacylglycerols, Membrane lipids
Ch. 33 Synthesis of Fatty acids, Triacylglycerols, Membrane lipids

... Glucose to pyruvate in mitochondrion, forms Ac CoA, OAA, which form citrate Citrate in cytosol then to Ac CoA, malonyl CoA Fatty acid synthesis involve series 2-C additions from malonyl CoA to the ω-C of Ac CoA onto FA synthase. Costs 2 NADPH and 1 ATP per cycle addition ...
Muscle Metabolism - Interactive Physiology
Muscle Metabolism - Interactive Physiology

MS Word Version - Interactive Physiology
MS Word Version - Interactive Physiology

... • The synthetic enzyme binds the ADP and catalyzes the reaction. During the reaction, water (shown attached to the ADP and phosphate groups in blue) splits off and the inorganic phosphate (Pi) attaches to the ADP to form ATP. • This process requires energy since a high energy bond is formed. The ene ...
Specific Activities of Enzymes of the Serine Pathway of Carbon
Specific Activities of Enzymes of the Serine Pathway of Carbon

... organisms when grown on methylamine possessed elevated activities of the enzymes serine hydroxymethyltransferase, hydroxypyruvate reductase, malate dehydrogenase, phosphoenolpyruvate carboxylase, serineglyoxylate aminotransferase and ATP malate lyase (Hersh & Bellion, 1972). The ratio of specific ac ...
Lipoic Acid 100 mg The Universal Antioxidant
Lipoic Acid 100 mg The Universal Antioxidant

... body as part of several multi-enzyme complexes located in the mitochondria. Alpha-lipoic acid is essential for metabolizing carbohydrates, proteins, and fats, for the conversion of their energy into ATP. Two of these enzyme complexes, pyruvate dehydrogenase (PDH) and alpha-ketoglutarate dehydrogenas ...
Biochemistry
Biochemistry

... infect other people. Such parasitizing is impossible for the following causative agent: A *Dysenteric amoeba B Malarial plasmodium C Intestinal trichomonad D Dermatotropic leishmania E Viscerotropic leishmania ...
Test 1
Test 1

... The standard free energy change for ATP hydrolysis is –30.5 kJ/mol and for glycerol-3phosphate hydrolysis is –9.2 kJ/mol. (a) Calculate ∆Go ' for the glycerokinase reaction: ...
Chapter 7: Cellular Pathways That Harvest Chemical Energy
Chapter 7: Cellular Pathways That Harvest Chemical Energy

Macromolecules
Macromolecules

... amino acid residues (an amino acid residue is the name given to an amino acid that is part of a polypeptide) – cysteine has a R = –CH2SH side-chain and two such side-chains can react to form disulphide bridges. Other long-range bonds involved include hydrogenbonds. These form domains, or large 3D st ...
Chapter 4 - Enzymes and Energy
Chapter 4 - Enzymes and Energy

...  Potential Energy  Stored energy, eg. in chemical bonds ...
Lec 12: Fatty acid biosynthesis
Lec 12: Fatty acid biosynthesis

... (because it inhibits fatty acid transport to mitochondria for degradation). Malonyl‐CoA is also the building block intermediate for fatty acid biosynthesis.. So think about the relationship between carbohydrates and fats… ...
View Full Page PDF - Advances in Physiology Education
View Full Page PDF - Advances in Physiology Education

... then converted to glucose by gluconeogenesis. Cytosolic fumarate is converted to cytosolic PEP via reactions 12 (cytosolic fumarase), 13 (cytosolic malate dehydrogenase), and 14 (PEPCK-C). The second PEP molecule is synthesized via the successive action of either reaction 7 (mitochondrial pyruvate c ...
Chapter 2 : The Chemistry of Life Section 3 : Carbon
Chapter 2 : The Chemistry of Life Section 3 : Carbon

... • Carbon has 4 valence electrons – meaning it can make up to 4 covalent bonds with itself or many other elements • Carbon can bond with itself in a single, double, or triple ...
Studies on the Physiological Significance of the Lack
Studies on the Physiological Significance of the Lack

Energy Ch6
Energy Ch6

... – Organisms Use the Energy of Sunlight to Maintain The Highly Organized (=Low-Entropy) Condition Known as Life ...
Biochemistry - Austin Community College
Biochemistry - Austin Community College

... • Enzymes are proteins that carry out most catalysis in living organisms. • Unlike heat, enzymes are highly specific. Each enzyme typically speeds up only one or a few chemical reactions. • Unique three-dimensional shape enables an enzyme to stabilize a temporary association between substrates. • Be ...
Worked solutions: Chapter 2 Human biochemistry
Worked solutions: Chapter 2 Human biochemistry

ijbbjune2k2
ijbbjune2k2

... Amino acid uptake and utilization of various nitrogen sources (amino acids, nitrite, nitrate and ammonia) were studied in Nostoc ANTH and its mutant (Het-Nif-) isolate defective in heterocyst formation and N2-fixation. Both parent and its mutant grew at the expense of glutamine, asparagine and argin ...
Problem set #3 Answers 1. The 3 main links between lipid synthesis
Problem set #3 Answers 1. The 3 main links between lipid synthesis

... cytoplasm mitochondrial matrix ________________________________________________ cofactors used in NADP:H FAD, NAD+ oxidation/reduction reactions ________________________________________________ hormonal control, if any glucagon inhibits not known insulin stimulates not known ________________________ ...
Chapter 8 Section 3 Notes
Chapter 8 Section 3 Notes

... The End Results The two sets of photosynthetic reactions work together—the lightdependent reactions trap the energy of sunlight in chemical form, and the light-independent reactions use that chemical energy to produce stable, high-energy sugars from carbon dioxide and water. In the process, animals, ...
breakdown of complex organic molecules into the simplest, stable
breakdown of complex organic molecules into the simplest, stable

Getting a good rate of exchange – the mitochondrial ADP
Getting a good rate of exchange – the mitochondrial ADP

... nitrogen atom in the backbone is bonded to a side-chain carbon atom. This unusual chemical structure has two important consequences; first, proline residues are rather rigid in terms of the allowed conformations of their main-chain, and second, there is no amide hydrogen atom that can be involved in ...
Translation - St. Robert CHS
Translation - St. Robert CHS

... • Every tRNA carries only one specific amino acid • The third base in each codon may differ b/w two codons that code for the same a.a. – E.g, AAU and AAC both code for tyrosine. ...
General clinical situations
General clinical situations

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Citric acid cycle



The citric acid cycle – also known as the tricarboxylic acid (TCA) cycle or the Krebs cycle – is a series of chemical reactions used by all aerobic organisms to generate energy through the oxidation of acetate derived from carbohydrates, fats and proteins into carbon dioxide and chemical energy in the form of adenosine triphosphate (ATP). In addition, the cycle provides precursors of certain amino acids as well as the reducing agent NADH that is used in numerous other biochemical reactions. Its central importance to many biochemical pathways suggests that it was one of the earliest established components of cellular metabolism and may have originated abiogenically.The name of this metabolic pathway is derived from citric acid (a type of tricarboxylic acid) that is consumed and then regenerated by this sequence of reactions to complete the cycle. In addition, the cycle consumes acetate (in the form of acetyl-CoA) and water, reduces NAD+ to NADH, and produces carbon dioxide as a waste byproduct. The NADH generated by the TCA cycle is fed into the oxidative phosphorylation (electron transport) pathway. The net result of these two closely linked pathways is the oxidation of nutrients to produce usable chemical energy in the form of ATP.In eukaryotic cells, the citric acid cycle occurs in the matrix of the mitochondrion. In prokaryotic cells, such as bacteria which lack mitochondria, the TCA reaction sequence is performed in the cytosol with the proton gradient for ATP production being across the cell's surface (plasma membrane) rather than the inner membrane of the mitochondrion.
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