LIPID-TRANSFER PROTEINS IN PLANTS
... acyl chains has also been demonstrated with a barley 7-kDa protein that has some features in common with LTPs (16) and with an LTP secreted from carrot embryogenic cultures that was found to be able to bind oleoyl-CoA in a near-equimolar ratio (42, 69). It can thus be concluded that the same protein ...
... acyl chains has also been demonstrated with a barley 7-kDa protein that has some features in common with LTPs (16) and with an LTP secreted from carrot embryogenic cultures that was found to be able to bind oleoyl-CoA in a near-equimolar ratio (42, 69). It can thus be concluded that the same protein ...
Vertebrate hairy and Enhancer of split related proteins
... We refer to the four subfamilies by the names of the prototypic protein for each: hairy, E(spl), Hey, and Stra13. Except for Stra13, each of these subfamilies has members from Drosophila to humans. Although all of these proteins are transcriptional repressors, the conserved dierences in the primary ...
... We refer to the four subfamilies by the names of the prototypic protein for each: hairy, E(spl), Hey, and Stra13. Except for Stra13, each of these subfamilies has members from Drosophila to humans. Although all of these proteins are transcriptional repressors, the conserved dierences in the primary ...
Quiz 2 Review Sheet
... into play or when only the backbone is involved, hydrophobic vs hydrophilic side chains, where different types of side chains are located in proteins typically, etc… 50.5. All alpha helices are right or left handed? This is because they are made with… 51. Explain why the levels of structure have lit ...
... into play or when only the backbone is involved, hydrophobic vs hydrophilic side chains, where different types of side chains are located in proteins typically, etc… 50.5. All alpha helices are right or left handed? This is because they are made with… 51. Explain why the levels of structure have lit ...
The mRNA-bound proteome of the early fly embryo
... Validation of RNA-binding activity of candidate RBPs To quantify protein enrichment in precipitates relative to protein abundance in early embryos, we ranked all early fly mRBPome proteins by their protein iBAQ ratio of oligo(dT) precipitate and embryo proteome and divided the protein set into three ...
... Validation of RNA-binding activity of candidate RBPs To quantify protein enrichment in precipitates relative to protein abundance in early embryos, we ranked all early fly mRBPome proteins by their protein iBAQ ratio of oligo(dT) precipitate and embryo proteome and divided the protein set into three ...
Centriole Duplication: Centrin in on Answers? Dispatch
... The centrosome is the microtubule organizing center of most higher eukaryotic cells, and is generally described as having two orthogonal centrioles surrounded by pericentriolar material. This description highlights the important role of centrioles as organizers of the pericentriolar material [1] tha ...
... The centrosome is the microtubule organizing center of most higher eukaryotic cells, and is generally described as having two orthogonal centrioles surrounded by pericentriolar material. This description highlights the important role of centrioles as organizers of the pericentriolar material [1] tha ...
Transducin (1)
... to full activation of guanylate cyclase subunits, and an increase in the rate of cGMP synthesis. ...
... to full activation of guanylate cyclase subunits, and an increase in the rate of cGMP synthesis. ...
Protein Interactions Limit the Rate of Evolution of
... Orthologs of protein sequences were retrieved with Blast (Altschul et al. 1997) using an e value of 104 as a lower limit cutoff. Genomes of Nostoc punctiforme and Trichodesmium erythraeum IMS101 were in draft form when this work was undertaken, and preliminary protein-coding sequences were download ...
... Orthologs of protein sequences were retrieved with Blast (Altschul et al. 1997) using an e value of 104 as a lower limit cutoff. Genomes of Nostoc punctiforme and Trichodesmium erythraeum IMS101 were in draft form when this work was undertaken, and preliminary protein-coding sequences were download ...
Lipid bylayers and Membranes
... • The term refers to the collection of mechanisms that regulate the passage of solutes such as ions and small molecules through biological membranes namely lipid bilayers that contain proteins embedded in them. • The regulation of passage through the membrane is due to selective membrane permeabilit ...
... • The term refers to the collection of mechanisms that regulate the passage of solutes such as ions and small molecules through biological membranes namely lipid bilayers that contain proteins embedded in them. • The regulation of passage through the membrane is due to selective membrane permeabilit ...
Gene Section COPS2 (COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis))
... et al., 2007; reviewed in: Papaioannou et al., 2007). Alien is recruited to the E2F1 gene promoter repressing endogenous E2F1 gene expression in vivo. The data also suggest that Alien inhibits transactivation of E2F1, a positive regulator of cell cycle progression. In line with this, Alien represses ...
... et al., 2007; reviewed in: Papaioannou et al., 2007). Alien is recruited to the E2F1 gene promoter repressing endogenous E2F1 gene expression in vivo. The data also suggest that Alien inhibits transactivation of E2F1, a positive regulator of cell cycle progression. In line with this, Alien represses ...
PDF Format - Kinexus Bioinformatics Corporation
... diagnosis, prognosis and treatment of human diseases. In particular, we track enzymes called protein kinases that control other proteins by carrying out their phosphorylation at regulatory sites known as phosphosites. Phosphosites act as on/off switches for proteins. Their malfunction has been linke ...
... diagnosis, prognosis and treatment of human diseases. In particular, we track enzymes called protein kinases that control other proteins by carrying out their phosphorylation at regulatory sites known as phosphosites. Phosphosites act as on/off switches for proteins. Their malfunction has been linke ...
Elements involved in light regulation of the parsley chs promoter: cis
... also behaved as a regulatory sequence necessary and sufficient for light induction (Wei Bhaar et al., manuscript in preparation). Taken together, these and other data (Block et al., 1990) demonstrate that the expression of the parsley chs gene in response to light is regulated by at least two separa ...
... also behaved as a regulatory sequence necessary and sufficient for light induction (Wei Bhaar et al., manuscript in preparation). Taken together, these and other data (Block et al., 1990) demonstrate that the expression of the parsley chs gene in response to light is regulated by at least two separa ...
Expression Differentiation Is Constrained to Low
... inhabit barrier islands of the southeastern United States, making them ideal for studying rapid adaptation. Snake venoms are comprised of approximately 20–100 toxic peptides and proteins (Calvete et al. 2010; Margres et al. 2014, 2015a) that collectively function in predation and defense. Although m ...
... inhabit barrier islands of the southeastern United States, making them ideal for studying rapid adaptation. Snake venoms are comprised of approximately 20–100 toxic peptides and proteins (Calvete et al. 2010; Margres et al. 2014, 2015a) that collectively function in predation and defense. Although m ...
Leukaemia Section t(6;14)(p25;q32) IRF4/IGH / t(2;6)(p12;p25) IRF4/IGK / t(6;22)(p25;q11) IRF4/IGL
... immunoglobulin heavy chain gene to the IRF4 gene have been shown to activate the transcription factor MUM1/IRF4 in multiple myeloma and in a subtype of mature B-cell lymphomas (Iida et al., 1997; Salaverria et al., 2011). The translocation leads to the overexpression of the MUM1/IRF4 gene. In multip ...
... immunoglobulin heavy chain gene to the IRF4 gene have been shown to activate the transcription factor MUM1/IRF4 in multiple myeloma and in a subtype of mature B-cell lymphomas (Iida et al., 1997; Salaverria et al., 2011). The translocation leads to the overexpression of the MUM1/IRF4 gene. In multip ...
The Psp system of Mycobacterium tuberculosis integrates envelope
... regulatory structure of the region, we used promoterprobe technology and constructed lacZ reporter fusions with DNA sequences upstream from clgR and within the clgR-pspA intergenic region (IG1 in Fig. 2A). When reporter gene expression was measured in response to surface stress, lacZ expression was ...
... regulatory structure of the region, we used promoterprobe technology and constructed lacZ reporter fusions with DNA sequences upstream from clgR and within the clgR-pspA intergenic region (IG1 in Fig. 2A). When reporter gene expression was measured in response to surface stress, lacZ expression was ...
Emerging biological roles of Cl− intracellular channel proteins
... in case of CLIC3 and CLIC5, isolated from macromolecular complexes (Berryman and Bretscher, 2000; Qian et al., 1999). Two splice variants of CLIC5, termed CLIC5A and CLIC5B (differing in length with 251 vs 410 aa, respectively), were identified in complex with cytoskeletal components (Berryman and B ...
... in case of CLIC3 and CLIC5, isolated from macromolecular complexes (Berryman and Bretscher, 2000; Qian et al., 1999). Two splice variants of CLIC5, termed CLIC5A and CLIC5B (differing in length with 251 vs 410 aa, respectively), were identified in complex with cytoskeletal components (Berryman and B ...
P1 and P2 protein heterodimer binding to the P0 protein of
... N-terminal domain (NTD) with the highly conserved GTPase-associated region (GAR) of the large rRNA subunit, and with two heterodimers of the acidic 12-kDa P1 and P2 proteins, ultimately forming a P0–(P1/P2)2 pentamer. Some lower eukaryotic species possess more than one P1 or P2 protein forms, such a ...
... N-terminal domain (NTD) with the highly conserved GTPase-associated region (GAR) of the large rRNA subunit, and with two heterodimers of the acidic 12-kDa P1 and P2 proteins, ultimately forming a P0–(P1/P2)2 pentamer. Some lower eukaryotic species possess more than one P1 or P2 protein forms, such a ...
Document
... Myoglobin (Mb) Oxygen binding/storage protein in muscle; may also play a part in local oxygen transport. O2 binds to haem. Maintenance of haem in Fe2+ form is necessary for O2 binding. Mb is a monomeric protein of about 150 aa. Haemoglobin A (HbA) O2 carrier in blood (red cells). Tetramer: 22. Qua ...
... Myoglobin (Mb) Oxygen binding/storage protein in muscle; may also play a part in local oxygen transport. O2 binds to haem. Maintenance of haem in Fe2+ form is necessary for O2 binding. Mb is a monomeric protein of about 150 aa. Haemoglobin A (HbA) O2 carrier in blood (red cells). Tetramer: 22. Qua ...
Drafting Patent Claims for Filing in the United States
... requires more than a mere statement that it is part of the invention and reference to a potential method for isolating it; what is required is a description of the DNA itself. Fiers v. Revel • For inventions in an unpredictable art, adequate written description of a genus which embraces widely varia ...
... requires more than a mere statement that it is part of the invention and reference to a potential method for isolating it; what is required is a description of the DNA itself. Fiers v. Revel • For inventions in an unpredictable art, adequate written description of a genus which embraces widely varia ...
Gene Section CLTC (clathrin heavy polypeptide) Atlas of Genetics and Cytogenetics
... Must not be confused with CLTCL1 (clathrin heavy polypeptide-like 1). ...
... Must not be confused with CLTCL1 (clathrin heavy polypeptide-like 1). ...
Ubiquitin and Plant Viruses, Let`s Play Together!
... has long been limited by the extreme paucity of known targets. It is only recently that a number of viral proteins acting in these processes have been identified and possible mechanisms proposed. It is likely that many more examples remain to be discovered. In some cases, viral proteins appear to usu ...
... has long been limited by the extreme paucity of known targets. It is only recently that a number of viral proteins acting in these processes have been identified and possible mechanisms proposed. It is likely that many more examples remain to be discovered. In some cases, viral proteins appear to usu ...
Comparative Genomics of the Genomic Region Controlling
... disease of maize in tropical and subtropical region causing yield loss in excess of 45%. The loci governing resistance (Rpp9, RppQ and RppD) have been mapped to 10.01 bins on short arm of maize chromosome 10, which also has genes for common rust resistance like Rp1 and Rp5. With the publication of m ...
... disease of maize in tropical and subtropical region causing yield loss in excess of 45%. The loci governing resistance (Rpp9, RppQ and RppD) have been mapped to 10.01 bins on short arm of maize chromosome 10, which also has genes for common rust resistance like Rp1 and Rp5. With the publication of m ...
Transcription
... sequences, but require protein factor, Rho in vivo transcripts often shorter than in vitro ...
... sequences, but require protein factor, Rho in vivo transcripts often shorter than in vitro ...
Functional specialization of Medicago truncatula leaves and
... Vitale 2005). Some PSV sorting signals have been identiWed, but in addition to speciWc sequence motifs these may also comprise arrangements of hydrophilic/charged and hydrophobic amino acid residues on the protein surface (Neuhaus 1996). In the developing cotyledons of legumes and most other plants, ...
... Vitale 2005). Some PSV sorting signals have been identiWed, but in addition to speciWc sequence motifs these may also comprise arrangements of hydrophilic/charged and hydrophobic amino acid residues on the protein surface (Neuhaus 1996). In the developing cotyledons of legumes and most other plants, ...
Chapter Sixteen: Control of Gene Expression
... Sex development in fruit flies depends on alternative splicing as well as a cascade of genetic regulation. Early in the development of female fruit flies, a femalespecific promoter is activated stimulating transcription at the sex-lethal (Sxl) gene. Splicing of the pre-mRNA of the transformer (tra) ...
... Sex development in fruit flies depends on alternative splicing as well as a cascade of genetic regulation. Early in the development of female fruit flies, a femalespecific promoter is activated stimulating transcription at the sex-lethal (Sxl) gene. Splicing of the pre-mRNA of the transformer (tra) ...
Helix BioMedix Invited To Present At SRI`s Peptides and Therapeutic
... immunity functions including antimicrobial, anti-inflammatory and stimulatory activities. HB50 is a broad spectrum topical anti-infective that effectively prevents S. aureus wound infection including infections caused by mupirocin resistant MRSA. Efficacy has also been demonstrated in this model wit ...
... immunity functions including antimicrobial, anti-inflammatory and stimulatory activities. HB50 is a broad spectrum topical anti-infective that effectively prevents S. aureus wound infection including infections caused by mupirocin resistant MRSA. Efficacy has also been demonstrated in this model wit ...
Protein moonlighting
Protein moonlighting (or gene sharing) is a phenomenon by which a protein can perform more than one function. Ancestral moonlighting proteins originally possessed a single function but through evolution, acquired additional functions. Many proteins that moonlight are enzymes; others are receptors, ion channels or chaperones. The most common primary function of moonlighting proteins is enzymatic catalysis, but these enzymes have acquired secondary non-enzymatic roles. Some examples of functions of moonlighting proteins secondary to catalysis include signal transduction, transcriptional regulation, apoptosis, motility, and structural.Protein moonlighting may occur widely in nature. Protein moonlighting through gene sharing differs from the use of a single gene to generate different proteins by alternative RNA splicing, DNA rearrangement, or post-translational processing. It is also different from multifunctionality of the protein, in which the protein has multiple domains, each serving a different function. Protein moonlighting by gene sharing means that a gene may acquire and maintain a second function without gene duplication and without loss of the primary function. Such genes are under two or more entirely different selective constraints.Various techniques have been used to reveal moonlighting functions in proteins. The detection of a protein in unexpected locations within cells, cell types, or tissues may suggest that a protein has a moonlighting function. Furthermore, sequence or structure homology of a protein may be used to infer both primary function as well as secondary moonlighting functions of a protein.The most well-studied examples of gene sharing are crystallins. These proteins, when expressed at low levels in many tissues function as enzymes, but when expressed at high levels in eye tissue, become densely packed and thus form lenses. While the recognition of gene sharing is relatively recent—the term was coined in 1988, after crystallins in chickens and ducks were found to be identical to separately identified enzymes—recent studies have found many examples throughout the living world. Joram Piatigorsky has suggested that many or all proteins exhibit gene sharing to some extent, and that gene sharing is a key aspect of molecular evolution. The genes encoding crystallins must maintain sequences for catalytic function and transparency maintenance function.Inappropriate moonlighting is a contributing factor in some genetic diseases, and moonlighting provides a possible mechanism by which bacteria may become resistant to antibiotics.