Our system for annotation of articles is named “Text
... consisted in just one sentence per article. In order to evaluate a gene/protein mention, our system takes into account all mentions of the possible gene/protein in the text. The context of all the instances is evaluated, and global features are extracted. That means that the results improve as the t ...
... consisted in just one sentence per article. In order to evaluate a gene/protein mention, our system takes into account all mentions of the possible gene/protein in the text. The context of all the instances is evaluated, and global features are extracted. That means that the results improve as the t ...
the versatile bacterial type iv secretion systems
... dynamic bacterial surface organelle, the activities of which are now known to include the contact-dependent delivery of DNA to bacterial recipients and the assembly and retraction of a conjugal PILUS2. In the past decade, reports describing systems that are ancestrally related to the F-transfer syst ...
... dynamic bacterial surface organelle, the activities of which are now known to include the contact-dependent delivery of DNA to bacterial recipients and the assembly and retraction of a conjugal PILUS2. In the past decade, reports describing systems that are ancestrally related to the F-transfer syst ...
![[1] "I"](http://s1.studyres.com/store/data/000195415_1-d0b3198b6b0330b220f5273d762f1288-300x300.png)
[1] "I"
... Use the data.frame() function to construct the ‘pplAges’ table out of ‘pplNames’ & ‘ages’ ...
... Use the data.frame() function to construct the ‘pplAges’ table out of ‘pplNames’ & ‘ages’ ...
Package `PPInfer`
... Description Interactions between proteins occur in many, if not most, biological processes. Most proteins perform their functions in networks associated with other proteins and other biomolecules. This fact has motivated the development of a variety of experimental methods for the identification of ...
... Description Interactions between proteins occur in many, if not most, biological processes. Most proteins perform their functions in networks associated with other proteins and other biomolecules. This fact has motivated the development of a variety of experimental methods for the identification of ...
Ch8IntrotoMetabolism_Enzymes
... Q: Based on this graph, is it an exergonic or endergonic reaction? ...
... Q: Based on this graph, is it an exergonic or endergonic reaction? ...
Human and fly protein-coding genes contain more stop resistant
... Human and fly protein-coding genes contain more stop resistant codons than random nucleotide sequences Francisco Prosdocimi1, J. Miguel Ortega1 ¹ Lab. Biodados, ICB-UFMG. It is well known that genetic code minimizes the effect of mutations and similar codons usually codify for the same amino acid, a ...
... Human and fly protein-coding genes contain more stop resistant codons than random nucleotide sequences Francisco Prosdocimi1, J. Miguel Ortega1 ¹ Lab. Biodados, ICB-UFMG. It is well known that genetic code minimizes the effect of mutations and similar codons usually codify for the same amino acid, a ...
on the garden pea
... The life sciences owe a lot to green peas. And perhaps even to the bishop of St Thomas Abbey in Brno – now the Czech Republic. It was there, in the 1850s, that Gregor Johann Mendel (1822-1884) decided to undertake studies on heredity using mice. The bishop, however, disagreed with research involving ...
... The life sciences owe a lot to green peas. And perhaps even to the bishop of St Thomas Abbey in Brno – now the Czech Republic. It was there, in the 1850s, that Gregor Johann Mendel (1822-1884) decided to undertake studies on heredity using mice. The bishop, however, disagreed with research involving ...
Yeast Two-Hybrid Screen
... Sequence and Characterize NIF1 ◦ Search Genebank for homologous structures in Arabidopsis ◦ NIF1 codes for last 2/3 of a bZIP Transcription ...
... Sequence and Characterize NIF1 ◦ Search Genebank for homologous structures in Arabidopsis ◦ NIF1 codes for last 2/3 of a bZIP Transcription ...
Biochemical and Biophysical Research Communications
... pathway is involved in the regulation of PCD [4]. Many apoptosis regulatory proteins have been identified as target substrates of ubiquitination. Bax, a proapoptotic Bcl-2 family member, undergoes a conformation change through apoptosis signaling and caspase activation, which leads to the protein’s d ...
... pathway is involved in the regulation of PCD [4]. Many apoptosis regulatory proteins have been identified as target substrates of ubiquitination. Bax, a proapoptotic Bcl-2 family member, undergoes a conformation change through apoptosis signaling and caspase activation, which leads to the protein’s d ...
Phylogenomics: improving functional predictions for uncharacterized
... methods will be more likely than phylogenomic methods to make inaccurate functional predictions (see Table 4). Another major advantage of phylogenetic methods over most similarity methods comes from the process of masking (see above). For example, a deletion of a large section of a gene in one speci ...
... methods will be more likely than phylogenomic methods to make inaccurate functional predictions (see Table 4). Another major advantage of phylogenetic methods over most similarity methods comes from the process of masking (see above). For example, a deletion of a large section of a gene in one speci ...
Sequence Alignment Techniques
... • Each iteration discovers intermediate sequences that are used in a sequence profile to discover more distant relatives of the query sequence in subsequent iterations • Potential problems with PSI-BLAST are associated with the potential for unrelated sequences to pollute the iterative search, and d ...
... • Each iteration discovers intermediate sequences that are used in a sequence profile to discover more distant relatives of the query sequence in subsequent iterations • Potential problems with PSI-BLAST are associated with the potential for unrelated sequences to pollute the iterative search, and d ...
Fibrinolytic Bacterial Enzymes with Thrombolytic Activity
... Enzymes are found throughout the natural world; the number of uses for them in various fields of industry in addition to medicine is staggering. Enzymes are found in animal and plant sources. Enzymes can be thought of as protein molecules with a specific mission—to initiate and regulate countless bi ...
... Enzymes are found throughout the natural world; the number of uses for them in various fields of industry in addition to medicine is staggering. Enzymes are found in animal and plant sources. Enzymes can be thought of as protein molecules with a specific mission—to initiate and regulate countless bi ...
The Kaposi`s sarcoma-associated herpesvirus ORF57 protein: a
... distinct stages of viral gene transcription: latent, IE (immediate early), early, and late. Expression of certain proteins of the IE class acts as the switch for transition from the latent state to the lytic replication cycle. These IE proteins do not require cellular protein synthesis for their tra ...
... distinct stages of viral gene transcription: latent, IE (immediate early), early, and late. Expression of certain proteins of the IE class acts as the switch for transition from the latent state to the lytic replication cycle. These IE proteins do not require cellular protein synthesis for their tra ...
Chapter 19 Biochemistry - American Public University System
... • The Food and Drug Administration (FDA) recommends that fats and oils compose less than 30% of total caloric intake. The FDA also recommends that no more than one-third of those fats (10% of total caloric intake) should be saturated fats. • A diet high in saturated fats increases the risk of artery ...
... • The Food and Drug Administration (FDA) recommends that fats and oils compose less than 30% of total caloric intake. The FDA also recommends that no more than one-third of those fats (10% of total caloric intake) should be saturated fats. • A diet high in saturated fats increases the risk of artery ...
PPT - Bioinformatics.ca
... inferred human-chimp ancestral genome – Positive training set: simulated variants based on mutation model aware of sequence context and primate substitution rates – Predictive features (63): VEP (Variant Effect Predictor) output, UCSC tracks, Encode tracks includes missense predictions and nucleot ...
... inferred human-chimp ancestral genome – Positive training set: simulated variants based on mutation model aware of sequence context and primate substitution rates – Predictive features (63): VEP (Variant Effect Predictor) output, UCSC tracks, Encode tracks includes missense predictions and nucleot ...
Gene Section EP300 (E1A binding protein p300) Atlas of Genetics and Cytogenetics
... p300 and CBP are highly related proteins implicated in transcriptional responses to various extracellular and intracellular signals with chromatin remodeling; they are non-DNA-binding transcriptional coactivators; they interact with transcriptional activators as well as repressors; p300 and CBP are ...
... p300 and CBP are highly related proteins implicated in transcriptional responses to various extracellular and intracellular signals with chromatin remodeling; they are non-DNA-binding transcriptional coactivators; they interact with transcriptional activators as well as repressors; p300 and CBP are ...
GluR-A C-terminal 10 residues constitute a binding motif
... Figure 1. a, Top, Representation of the chimeric bait comprising the proximal 40 amino residues of the GluR-B Cterminal domain (R-B) fused to the C-terminal 10 residues of GluR-A (R-At10); Gal4 BD, Gal4 DNA-binding domain. Bottom, Representation of RIL and the isolated RIL clones (numbers = amino re ...
... Figure 1. a, Top, Representation of the chimeric bait comprising the proximal 40 amino residues of the GluR-B Cterminal domain (R-B) fused to the C-terminal 10 residues of GluR-A (R-At10); Gal4 BD, Gal4 DNA-binding domain. Bottom, Representation of RIL and the isolated RIL clones (numbers = amino re ...
Diapositiva 1 - Universidad Autonoma de Madrid
... TCGCCT-AC---T-CAA---C-CAGGCTTT TCGCCT-ACATTTTCCC---C-CAGGCTTT ...
... TCGCCT-AC---T-CAA---C-CAGGCTTT TCGCCT-ACATTTTCCC---C-CAGGCTTT ...
Gene Section FOXC1 (forkhead box C1) Atlas of Genetics and Cytogenetics
... upstream of the FOXC1 forkhead domain. The team also identified a C-to-T transition within the forkhead domain, causing a ser131-to-leu (S131L) amino acid substitution. The Nishimura team found a C-to-G transversion within the forkhead domain. This change resulted in an ile126-to-met (I126M) amino a ...
... upstream of the FOXC1 forkhead domain. The team also identified a C-to-T transition within the forkhead domain, causing a ser131-to-leu (S131L) amino acid substitution. The Nishimura team found a C-to-G transversion within the forkhead domain. This change resulted in an ile126-to-met (I126M) amino a ...
Golgi Apparatus
... The basic function of the Golgi apparatus is the transport of proteins within the cell. The Golgi receives materials for transportation through the cis face and sends the materials through to the trans face once they are packaged and modified into the vesicles. It functions in the collection, packa ...
... The basic function of the Golgi apparatus is the transport of proteins within the cell. The Golgi receives materials for transportation through the cis face and sends the materials through to the trans face once they are packaged and modified into the vesicles. It functions in the collection, packa ...
Protein Targeting to the Nuclear Pore. What Can
... it is possible that all of the NLS import factors remain associated with the nucleus, and possibly other structures in the cytoplasm, after the protoplasts are permeabilized. Although these observations are unique to plants, it is difficult to test the function of putative plant NLS import factors b ...
... it is possible that all of the NLS import factors remain associated with the nucleus, and possibly other structures in the cytoplasm, after the protoplasts are permeabilized. Although these observations are unique to plants, it is difficult to test the function of putative plant NLS import factors b ...
Ch 18 - Bob Bruner`s Chemistry and Molecular Biology Resources
... A consequence is that certain mutations that might naively appear to be neutral are not necessarily neutral. A change from one proline codon to another might seem neutral; however, if the change is from a codon that is easy to translate to one more difficult to translate, it might well slow down the ...
... A consequence is that certain mutations that might naively appear to be neutral are not necessarily neutral. A change from one proline codon to another might seem neutral; however, if the change is from a codon that is easy to translate to one more difficult to translate, it might well slow down the ...
Identification of a NodD repressible gene
... deletion mutation was made and proteins produced by the mutant were compared with those by wild-type using 2D gel electrophoresis. Several protein differences were identified suggesting that this small gene influences the expression or stability of these proteins. However, the mutant nodulated its h ...
... deletion mutation was made and proteins produced by the mutant were compared with those by wild-type using 2D gel electrophoresis. Several protein differences were identified suggesting that this small gene influences the expression or stability of these proteins. However, the mutant nodulated its h ...
In vitro translation with non
... The Collighan research group has extensive experience of working with firefly luciferase. They have generated mutations that improve thermostability or detergent stability, alter kinetics and change emitted light colour. With the exquisite sensitivity that light detection offers, firefly luciferase ...
... The Collighan research group has extensive experience of working with firefly luciferase. They have generated mutations that improve thermostability or detergent stability, alter kinetics and change emitted light colour. With the exquisite sensitivity that light detection offers, firefly luciferase ...
Protein moonlighting
Protein moonlighting (or gene sharing) is a phenomenon by which a protein can perform more than one function. Ancestral moonlighting proteins originally possessed a single function but through evolution, acquired additional functions. Many proteins that moonlight are enzymes; others are receptors, ion channels or chaperones. The most common primary function of moonlighting proteins is enzymatic catalysis, but these enzymes have acquired secondary non-enzymatic roles. Some examples of functions of moonlighting proteins secondary to catalysis include signal transduction, transcriptional regulation, apoptosis, motility, and structural.Protein moonlighting may occur widely in nature. Protein moonlighting through gene sharing differs from the use of a single gene to generate different proteins by alternative RNA splicing, DNA rearrangement, or post-translational processing. It is also different from multifunctionality of the protein, in which the protein has multiple domains, each serving a different function. Protein moonlighting by gene sharing means that a gene may acquire and maintain a second function without gene duplication and without loss of the primary function. Such genes are under two or more entirely different selective constraints.Various techniques have been used to reveal moonlighting functions in proteins. The detection of a protein in unexpected locations within cells, cell types, or tissues may suggest that a protein has a moonlighting function. Furthermore, sequence or structure homology of a protein may be used to infer both primary function as well as secondary moonlighting functions of a protein.The most well-studied examples of gene sharing are crystallins. These proteins, when expressed at low levels in many tissues function as enzymes, but when expressed at high levels in eye tissue, become densely packed and thus form lenses. While the recognition of gene sharing is relatively recent—the term was coined in 1988, after crystallins in chickens and ducks were found to be identical to separately identified enzymes—recent studies have found many examples throughout the living world. Joram Piatigorsky has suggested that many or all proteins exhibit gene sharing to some extent, and that gene sharing is a key aspect of molecular evolution. The genes encoding crystallins must maintain sequences for catalytic function and transparency maintenance function.Inappropriate moonlighting is a contributing factor in some genetic diseases, and moonlighting provides a possible mechanism by which bacteria may become resistant to antibiotics.