Nucleic Acid metabolism De Novo Synthesis of Purine
... from nucleic acids or the energy pool are acted upon by nucleotidases and pyrimidine nucleoside phosphorylase to yield the free bases. The 4-amino group of both cytosine and 5-methyl cytosine is released as ammonia. ...
... from nucleic acids or the energy pool are acted upon by nucleotidases and pyrimidine nucleoside phosphorylase to yield the free bases. The 4-amino group of both cytosine and 5-methyl cytosine is released as ammonia. ...
syllabus
... Tom Brody, 2nd Edition, Academic Press 4. Dietary Reference Intakes (2000) for thiamin, riboflavin, niacin, vitamin B6, folate, vitamin B12, pantothenic acid, biotin, and choline National Academy Press, Washington, D.C. 5. 國人膳食營養素參考攝取量及其說明 行政院衛生署 修訂第六版 92 年 9 月 6. Handouts from NS103 course in the D ...
... Tom Brody, 2nd Edition, Academic Press 4. Dietary Reference Intakes (2000) for thiamin, riboflavin, niacin, vitamin B6, folate, vitamin B12, pantothenic acid, biotin, and choline National Academy Press, Washington, D.C. 5. 國人膳食營養素參考攝取量及其說明 行政院衛生署 修訂第六版 92 年 9 月 6. Handouts from NS103 course in the D ...
Statistical Analyses of Microarray Data
... foreign species cRNAs to hybridization mixture • Set A: 11 control cRNAs were spiked in, all at the same concentration, which varied across chips. • Set B: 11 control cRNAs were spiked in, all at different concentrations, which varied across chips. The concentrations were arranged in 12x12 cyclic La ...
... foreign species cRNAs to hybridization mixture • Set A: 11 control cRNAs were spiked in, all at the same concentration, which varied across chips. • Set B: 11 control cRNAs were spiked in, all at different concentrations, which varied across chips. The concentrations were arranged in 12x12 cyclic La ...
Prezentace aplikace PowerPoint
... Take over http://www.indstate.edu/thcme/mwking/aminoacidderivatives.html ...
... Take over http://www.indstate.edu/thcme/mwking/aminoacidderivatives.html ...
CLW-web page-05
... area stems from the wealth of structural diversity of marine natural products assembled on a tetrahydropyran core. Prins-type cyclisations have the potential to give versatile and efficient approaches to the synthesis of substituted tetrahydropyrans. In collaboration with Professor Roger Alder we ar ...
... area stems from the wealth of structural diversity of marine natural products assembled on a tetrahydropyran core. Prins-type cyclisations have the potential to give versatile and efficient approaches to the synthesis of substituted tetrahydropyrans. In collaboration with Professor Roger Alder we ar ...
BCHEM 254 – METABOLISM IN HEALTH AND DISEASES II Lecture
... purines and pyrimidines. Purines consist of two fused nitrogen-containing rings with a total of nine ring atoms. Pyridmidines have only a six-membered nitrogencontaining ring. Purines and pyrimidines are "flat", hydrophobic, aromatic molecules that absorb ultraviolet light (260 nm). There are two pu ...
... purines and pyrimidines. Purines consist of two fused nitrogen-containing rings with a total of nine ring atoms. Pyridmidines have only a six-membered nitrogencontaining ring. Purines and pyrimidines are "flat", hydrophobic, aromatic molecules that absorb ultraviolet light (260 nm). There are two pu ...
Intermediary metabolism
... Smooth ER • synthesis of triacylglycerols and phospholipids • elongation and desaturation of fatty acids • synthesis of steroids • biotransformation of xenobiotics ...
... Smooth ER • synthesis of triacylglycerols and phospholipids • elongation and desaturation of fatty acids • synthesis of steroids • biotransformation of xenobiotics ...
STARVE-FEED CYCLE 1) WELL-FED STATE (food intake
... • ↑ malonyl-CoA inhibits carnitine palmitoyl transferase I (= β-oxidation) 3) covalent modification of enzymes • phosphorylation (protein kinases) / dephosphorylation (protein phosphatases) • some phosphorylated enzymes are active (glycogen phosphorylase) other inactive (glycogen synthase) 4) change ...
... • ↑ malonyl-CoA inhibits carnitine palmitoyl transferase I (= β-oxidation) 3) covalent modification of enzymes • phosphorylation (protein kinases) / dephosphorylation (protein phosphatases) • some phosphorylated enzymes are active (glycogen phosphorylase) other inactive (glycogen synthase) 4) change ...
Synthesis, Isolation and Purification of an Ester
... 2.10 The student can design and/or interpret the results of a separation experiment (filtration, paper chromatography, column chromatography, or distillation) in terms of the relative strength of interactions among and between the components. 3.3 The student is able to use stoichiometric calculati ...
... 2.10 The student can design and/or interpret the results of a separation experiment (filtration, paper chromatography, column chromatography, or distillation) in terms of the relative strength of interactions among and between the components. 3.3 The student is able to use stoichiometric calculati ...
ppt
... Types of Chemical Reactions • Atoms and molecules react to create chemical reactions. • There are thousands of different chemical reactions, where atoms are never lost, just rearranged. ...
... Types of Chemical Reactions • Atoms and molecules react to create chemical reactions. • There are thousands of different chemical reactions, where atoms are never lost, just rearranged. ...
Protein mteabolism
... Serotonin is popularly thought to be a contributor to feelings of well-being and happiness. Approximately 90% of the human body's total serotonin is located in the intestine, where it is used to regulate intestinal movements. The remainder is synthesized in neurons of the CNS, where it has various ...
... Serotonin is popularly thought to be a contributor to feelings of well-being and happiness. Approximately 90% of the human body's total serotonin is located in the intestine, where it is used to regulate intestinal movements. The remainder is synthesized in neurons of the CNS, where it has various ...
Biosynthesis of Essential Amino Acids
... both valine and isoleucine. Assuming that there was a primordial set of enzymes with dual substrate specificity that synthesized both glutamate and leucine, give at least two good reasons for the evolution of two separate sets of enzymes. These must be reasons that do not exist for the valine-isoleu ...
... both valine and isoleucine. Assuming that there was a primordial set of enzymes with dual substrate specificity that synthesized both glutamate and leucine, give at least two good reasons for the evolution of two separate sets of enzymes. These must be reasons that do not exist for the valine-isoleu ...
Synthesis of F-18 Fluoroestradiol (FES)
... ammonium carbonate or potassium carbonate/Kryptofix® under standard conditions. Fluoride incorporation yields are typically >90% and have exceeded 99%. Only one fluorination product is formed under these conditions. If much less than 10 micromoles of starting material is used there is a second radio ...
... ammonium carbonate or potassium carbonate/Kryptofix® under standard conditions. Fluoride incorporation yields are typically >90% and have exceeded 99%. Only one fluorination product is formed under these conditions. If much less than 10 micromoles of starting material is used there is a second radio ...
Lipid Biosynthesis - Chemistry Courses: About: Department
... A) Condensation of precursors. B) Rearrangement. C) Reduction. D) Dehydration. 3. Which of the following is the regulated step of fatty acid synthesis in eukaryotes? A) Carboxylation of acetyl CoA. B) Transportation of mitochondrial acetyl CoA into the cytosol. C) Assembly of the fatty acid chain. D ...
... A) Condensation of precursors. B) Rearrangement. C) Reduction. D) Dehydration. 3. Which of the following is the regulated step of fatty acid synthesis in eukaryotes? A) Carboxylation of acetyl CoA. B) Transportation of mitochondrial acetyl CoA into the cytosol. C) Assembly of the fatty acid chain. D ...
Ch 28 Reading guide
... 3. What is the role of citrate lyase? What hormone leads to its activation? 4. The synthesis of palmitate requires _____ molecules of NADPH as well as __________. 5. The shuttle that returns oxaloacetate back to the matrix also produces _____________, which is needed in fatty acid synthesis. 6. Draw ...
... 3. What is the role of citrate lyase? What hormone leads to its activation? 4. The synthesis of palmitate requires _____ molecules of NADPH as well as __________. 5. The shuttle that returns oxaloacetate back to the matrix also produces _____________, which is needed in fatty acid synthesis. 6. Draw ...
Nucleotides
... deoxyribonucleotides, the disulfide bond created during the production of the 2'-deoxy carbon must be reduced The source of the reducing equivalents for this purpose is thioredoxin—a peptide coenzyme of ribonucleotide reductase Thioredoxin contains two cysteine residues separated by two amino ac ...
... deoxyribonucleotides, the disulfide bond created during the production of the 2'-deoxy carbon must be reduced The source of the reducing equivalents for this purpose is thioredoxin—a peptide coenzyme of ribonucleotide reductase Thioredoxin contains two cysteine residues separated by two amino ac ...
Practical Methods for Biocatalysis and Biotransformations Brochure
... More information from http://www.researchandmarkets.com/reports/2174997/ ...
... More information from http://www.researchandmarkets.com/reports/2174997/ ...
幻灯片 1
... phosphoramidites 亚磷酰胺 ) is activated by an acidic azoles catalyst, tetrazole (四唑), 2-ethylthiotetrazole, 2-bezylthiotetrazole, 4,5dicyanoimidazole, or a number of similar compounds. This mixture is brought in contact with the starting solid support (first coupling) or oligonucleotide precursor (foll ...
... phosphoramidites 亚磷酰胺 ) is activated by an acidic azoles catalyst, tetrazole (四唑), 2-ethylthiotetrazole, 2-bezylthiotetrazole, 4,5dicyanoimidazole, or a number of similar compounds. This mixture is brought in contact with the starting solid support (first coupling) or oligonucleotide precursor (foll ...
Chapter 21 Biosynthetic Pathways
... • The biosynthesis of other di-, oligo-, and polysaccharides also uses this common activation step to form an appropriate UDP derivative. ...
... • The biosynthesis of other di-, oligo-, and polysaccharides also uses this common activation step to form an appropriate UDP derivative. ...
Antimicrobial Agents
... Semi-synthetic agents - derivatives of natural agents altered in laboratory by adding chemical groups (to improve effectiveness, etc.) C. Criteria that determines the effectiveness of antimicrobial agents used in the treatment of infectious diseases: ...
... Semi-synthetic agents - derivatives of natural agents altered in laboratory by adding chemical groups (to improve effectiveness, etc.) C. Criteria that determines the effectiveness of antimicrobial agents used in the treatment of infectious diseases: ...
C454_lect12 - chem.uwec.edu - University of Wisconsin
... carboxyphosphate The carbamic acid is channeled another 35Å to the site where it is phosphorylated ...
... carboxyphosphate The carbamic acid is channeled another 35Å to the site where it is phosphorylated ...
Lecture 12 - Nucleotide Biosynthesis - chem.uwec.edu
... carboxyphosphate The carbamic acid is channeled another 35Å to the site where it is phosphorylated ...
... carboxyphosphate The carbamic acid is channeled another 35Å to the site where it is phosphorylated ...
Oligonucleotide synthesis
Oligonucleotide synthesis is the chemical synthesis of relatively short fragments of nucleic acids with defined chemical structure (sequence). The technique is extremely useful in current laboratory practice because it provides a rapid and inexpensive access to custom-made oligonucleotides of the desired sequence. Whereas enzymes synthesize DNA and RNA only in a 5' to 3' direction, chemical oligonucleotide synthesis does not suffer from this limitation, although it is, most often, carried out in the opposite, 3' to 5' direction. Currently, the process is implemented as solid-phase synthesis using phosphoramidite method and phosphoramidite building blocks derived from protected 2'-deoxynucleosides (dA, dC, dG, and T), ribonucleosides (A, C, G, and U), or chemically modified nucleosides, e.g. LNA, BNA.To obtain the desired oligonucleotide, the building blocks are sequentially coupled to the growing oligonucleotide chain in the order required by the sequence of the product (see Synthetic cycle below). The process has been fully automated since the late 1970s. Upon the completion of the chain assembly, the product is released from the solid phase to solution, deprotected, and collected. The occurrence of side reactions sets practical limits for the length of synthetic oligonucleotides (up to about 200 nucleotide residues) because the number of errors accumulates with the length of the oligonucleotide being synthesized. Products are often isolated by high-performance liquid chromatography (HPLC) to obtain the desired oligonucleotides in high purity. Typically, synthetic oligonucleotides are single-stranded DNA or RNA molecules around 15–25 bases in length.Oligonucleotides find a variety of applications in molecular biology and medicine. They are most commonly used as antisense oligonucleotides, small interfering RNA, primers for DNA sequencing and amplification, probes for detecting complementary DNA or RNA via molecular hybridization, tools for the targeted introduction of mutations and restriction sites, and for the synthesis of artificial genes.