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Reverse Transcription - St. Michael`s Hospital
Reverse Transcription - St. Michael`s Hospital

... Synthesis of cDNA from purified poly(A)+ or total RNA is performed by the action of a reverse  transcriptase, typically isolated from retrovirus. The reverse transcriptase has three biochemical  activities: as a RNA‐dependent DNA polymerase, a DNA‐dependent DNA polymerase and ribonuclease  H. Many c ...
Lecture3
Lecture3

11. Origin and evolution of life (part I)
11. Origin and evolution of life (part I)

... itself so that the genetic information is passed on to the daughter cells (Fig. 3B). DNA replication requires protein enzymes to split the double-stranded DNA molecule and help connecting each strands with free nucleotides. The information for building these proteins is encoded in DNA. Life as we kn ...
Carbohydrate Metabolism Updated
Carbohydrate Metabolism Updated

Other Pathways of Carbohydrate Metabolism Gluconeogenesis
Other Pathways of Carbohydrate Metabolism Gluconeogenesis

Chapter 3 The Same 20 Amino Acids Serve as Building Blocks for
Chapter 3 The Same 20 Amino Acids Serve as Building Blocks for

... 9.1 Peptides of up to 150 residues can be synthesized by automated solid-phase methods mainly invented by R. Bruce Merrifield (who won the 1984 Nobel Prize in Chemistry for this). ...
Critical assessment of side chain conformation prediction in
Critical assessment of side chain conformation prediction in

... by the authors. Then, we allowed the programs to rebuild all the side chains of each mutant lysozyme. For SCWRL3.0, no additional settings for the repacking algorithm are present, apart from the choice of side chains to be repacked. For NCN, default options of the program were applied (Peterson et a ...
Lipopolysaccharide with 2,3-diamino-2,3
Lipopolysaccharide with 2,3-diamino-2,3

... lipopolysaccharides of P. diminuta and P. vesicularis show a different fatty acid spectrum [11], that of R. palustris has not yet been worked out in detail [12]. The data confirm previous findings on the conservative structure of the backbone of lipid A: one distinct type can be common to a group of ...
Enzymes I – What Is an Enzyme?
Enzymes I – What Is an Enzyme?

Sequencing genomes
Sequencing genomes

... A new species of frog has been introduced into an area where it has too few natural predators. In an attempt to restore the ecological balance, a team of scientists is considering introducing a species of bird which feeds on this frog. Experimental data suggests that the population of frogs and bird ...
Characteristics of Living Things (Essay
Characteristics of Living Things (Essay

... Part b. Please identify & briefly explain at least six unifying characteristics of all living organisms on our planet. All of out planet’s organisms can either be categorized as prokaryotes or eukaryotes. Please explain four ways that prokaryotic & eukaryotic organisms differ structurally, and in wa ...
The Origin and Evolution of Life on Earth
The Origin and Evolution of Life on Earth

... Next goal is to combine Monomers into Polymers (peptide chains) ...
Assignment 5 Bioenergy/ Photosynthesis
Assignment 5 Bioenergy/ Photosynthesis

... 1. (5) Define the following terms that relate to an enzyme: activation energy, active site, conformation, denaturation, and coenzyme/cofactor binding site? Enzymes are proteins and therefore must be folded or conformed into a specific shape to be functional. Their function is to assist the occurrenc ...
Nucleotides: Be able to differentiate between a purine ring and a
Nucleotides: Be able to differentiate between a purine ring and a

... it does not transfer C at the oxidation level of the carbonyl, that is done by biotin with one exception, it does not transfer C at the oxidation level of the methyl group, that is done by SAM Folate must be provided in the diet Folate must be reduced (two different double bonds are reduced to singl ...
Chapter 2b Packet answers
Chapter 2b Packet answers

... 5. The starting materials for chemical reactions are called _reactants__, while thenew substances that are formed are called __products__. 6. The energy needed to start a chemical reaction is called ____activation energy__. 7. A chemical reaction can be sped up by adding a substance called a(n) __en ...
Foreign Body Response
Foreign Body Response

...  multinucleated foreign body giant cells  fibrous encapsulation ...
Document
Document

... represented by carboxylic acid function, enolic function hydroxamic acid function a sulfonamide or tetrazole. The activity of ester and amide derivatives of carboxylic acid is attributed to the metabolic hydrolysis product. The center of acidity is located on carbon atom adjacent to a flat surface r ...
Nucleotides: Synthesis and Degradation
Nucleotides: Synthesis and Degradation

... ATP is involved in 6 steps PRPP in the first step of Purine synthesis is also a precursor for Pyrimidine Synthesis, His and Trp synthesis – Role of ATP in first step is unique– group transfer rather than ...
genes
genes

... They act as: •Enzymes •Structural Support •Transporters •Signals ...
classification of enzymes
classification of enzymes

Document
Document

... The bottom line of states are the main states (M) •These model the columns of the alignment The second row of diamond shaped states are called the insert states (I) •These are used to model the highly variable regions in the alignment. The top row or circles are delete states (D) •These are silent ...
Chemistry PPT
Chemistry PPT

... there are other chemicals that can trigger the same sensation. • We perceive sweetness when molecules of a substance attach to the “sweet” taste receptors on our tongue, triggering a message to the brain. • Many different kinds of molecules can bind to our “sweet” taste receptors, each causing a sim ...
Chemotropism of Achlya ambisexualis to Methionine
Chemotropism of Achlya ambisexualis to Methionine

... in the presence of other amino acids such as glutamic acid, aspartic acid, leucine or phenylalanine, may serve as a substrate for methionine synthesis (Lehninger, 1975). The tropic responses of Achlya to small peptides are shown in Table 1(d). Of the small peptides tested only methionine-containing ...
Biological Molecules
Biological Molecules

... (plants) alter characteristics in membranes ...
Pinar Tulay cell molecules_17
Pinar Tulay cell molecules_17

... • Lipids are a broad group of water-insoluble compounds that include triglycerides, phospholipids, steroids, and special-purpose lipids. • Lipids function as concentrated energy sources for cell metabolism, structural components of cell membranes, and regulatory molecules. ...
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Biosynthesis



Biosynthesis (also called biogenesis or anabolism) is a multi-step, enzyme-catalyzed process where substrates are converted into more complex products in living organisms. In biosynthesis, simple compounds are modified, converted into other compounds, or joined together to form macromolecules. This process often consists of metabolic pathways. Some of these biosynthetic pathways are located within a single cellular organelle, while others involve enzymes that are located within multiple cellular organelles. Examples of these biosynthetic pathways include the production of lipid membrane components and nucleotides.The prerequisite elements for biosynthesis include: precursor compounds, chemical energy (e.g. ATP), and catalytic enzymes which may require coenzymes (e.g.NADH, NADPH). These elements create monomers, the building blocks for macromolecules. Some important biological macromolecules include: proteins, which are composed of amino acid monomers joined via peptide bonds, and DNA molecules, which are composed of nucleotides joined via phosphodiester bonds.
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