Daratumumab-mediated lysis of primary multiple
... decade, the disease remains incurable, even with combination therapies with effective novel pharmacological agents.2-5 An attractive novel alternative to these treatments is the targeting of MM with therapeutic antibodies, as already standard-of-care in several other hematologic malignancies. Theref ...
... decade, the disease remains incurable, even with combination therapies with effective novel pharmacological agents.2-5 An attractive novel alternative to these treatments is the targeting of MM with therapeutic antibodies, as already standard-of-care in several other hematologic malignancies. Theref ...
RGD-dependent Linkage between Plant Cell Wall and Plasma
... bacteria, membrane-cell wall interactions have been considered vital for the proper control and coordination of cell division (23). Indeed, morphologically distinct attachment sites between the cytoplasmic membrane and outer membrane/ cell wall of gram-negative bacteria, termed zones of adhesion, ha ...
... bacteria, membrane-cell wall interactions have been considered vital for the proper control and coordination of cell division (23). Indeed, morphologically distinct attachment sites between the cytoplasmic membrane and outer membrane/ cell wall of gram-negative bacteria, termed zones of adhesion, ha ...
Lymphoid B cells induce NF-jB activation in high endothelial cells
... Lymphocyte-induced high endothelial cell activation in lymphocyte/HEV communication implicated during normal lymphocyte transmigration have remained relatively unexplored. A particular aspect addressed in the present work deals with the participation of nuclear factor jB (NF-jB) transcription facto ...
... Lymphocyte-induced high endothelial cell activation in lymphocyte/HEV communication implicated during normal lymphocyte transmigration have remained relatively unexplored. A particular aspect addressed in the present work deals with the participation of nuclear factor jB (NF-jB) transcription facto ...
What is cellular Senescence? - Roswell Park Cancer Institute
... Primary cells reach Replicative Senescence after several passages in culture (telomere erosion) . DNA damage and oxidative stress can induce senescence (SIS or Stress induced senescence) Oncogenic stimuli also induces senescence (OIS or Oncogene induced senescence) OIS and SIS can be referred as Pre ...
... Primary cells reach Replicative Senescence after several passages in culture (telomere erosion) . DNA damage and oxidative stress can induce senescence (SIS or Stress induced senescence) Oncogenic stimuli also induces senescence (OIS or Oncogene induced senescence) OIS and SIS can be referred as Pre ...
Grade 6 Cards 1. Plant and animal cells have some similarities as
... wastewater hazardous waste A-2 ...
... wastewater hazardous waste A-2 ...
Export To Word
... The transmission of a nerve impulse along a neuron from one end to the other occurs as a result of electrical changes across the membrane of the neuron. This tutorial will help students to visualize and understand the transmission of a nerve impulse. This game is based on several Novel Prizes in Phy ...
... The transmission of a nerve impulse along a neuron from one end to the other occurs as a result of electrical changes across the membrane of the neuron. This tutorial will help students to visualize and understand the transmission of a nerve impulse. This game is based on several Novel Prizes in Phy ...
Characteristics of Living Things
... - A single fertilized egg divides again and again. - As these cells divide and differentiate = they begin to look different from one another and to perform different functions. ...
... - A single fertilized egg divides again and again. - As these cells divide and differentiate = they begin to look different from one another and to perform different functions. ...
Exams - New Jersey Institute of Technology
... Multiple Choice. Write the capital letter of the correct answer on the space provided. (3-pts. Each) ___1. The first person to see a “cell” was a. Anton van Leewenhoek. b. Robert Hooke. c. Matthew Schleiden d. Rudolph Virchow ___2. The part of the cell that regulates what enters and leaves the cell ...
... Multiple Choice. Write the capital letter of the correct answer on the space provided. (3-pts. Each) ___1. The first person to see a “cell” was a. Anton van Leewenhoek. b. Robert Hooke. c. Matthew Schleiden d. Rudolph Virchow ___2. The part of the cell that regulates what enters and leaves the cell ...
Cells the Localization of Skin Tropic Memory T Skin Metabolites
... expression during in vitro T cell activation depended on the addition of soluble skin factors that were produced by epidermal tissue (12). Moreover, cultured keratinocytes but not dermal fibroblasts or skin-unrelated epithelial cell lines produced CCR8inducing factors, emphasizing the skin selectivi ...
... expression during in vitro T cell activation depended on the addition of soluble skin factors that were produced by epidermal tissue (12). Moreover, cultured keratinocytes but not dermal fibroblasts or skin-unrelated epithelial cell lines produced CCR8inducing factors, emphasizing the skin selectivi ...
Plant chaperonins: a role in microtubule
... Bright Italia) was cultivated in fresh modified Heller medium (Heller 1953) supplemented with 5 gM 1-naphthylacetic acid and 5 gM 2,4-dichlorophenoxyacetic acid. The culture was subcultivated every three weeks at an inoculation density of 5 9104 cells per ml. Under these conditions maximal division ...
... Bright Italia) was cultivated in fresh modified Heller medium (Heller 1953) supplemented with 5 gM 1-naphthylacetic acid and 5 gM 2,4-dichlorophenoxyacetic acid. The culture was subcultivated every three weeks at an inoculation density of 5 9104 cells per ml. Under these conditions maximal division ...
March 2017 - Human Metabolome Technologies
... treatment. Tumorigenesis is associated with unexpected alterations in cellular metabolism that arise from the need for cancer cells to generate the energy and biomass that is necessary to maintain cell growth and proliferation. As a result, cancer metabolism represents the greatest opportunity for t ...
... treatment. Tumorigenesis is associated with unexpected alterations in cellular metabolism that arise from the need for cancer cells to generate the energy and biomass that is necessary to maintain cell growth and proliferation. As a result, cancer metabolism represents the greatest opportunity for t ...
BLOOD and BONE MARROW
... iii) NO nucleus, NO cellular organelles iv) contains hemoglobin (carries O2 and CO2) b) leukocytes (WBCs) i) all contain azurophilic granules! ii) granulocytes: neutrophils, eosinophils, basophils iii) agranulocytes: lymphocytes (T/B/plasma cells), monocytes c) platelets i) come from megakaryocytes ...
... iii) NO nucleus, NO cellular organelles iv) contains hemoglobin (carries O2 and CO2) b) leukocytes (WBCs) i) all contain azurophilic granules! ii) granulocytes: neutrophils, eosinophils, basophils iii) agranulocytes: lymphocytes (T/B/plasma cells), monocytes c) platelets i) come from megakaryocytes ...
Clinical Genomic Analysis and Diagnosis -
... used to rebuild damaged t issues. Although many questions are still unanswered, most physicians and scientists nowadays have reported that regeneration in humans from the body's own tissues is feasible. Regeneration is a regulative developmental process ubiquitous across all human organs. It functio ...
... used to rebuild damaged t issues. Although many questions are still unanswered, most physicians and scientists nowadays have reported that regeneration in humans from the body's own tissues is feasible. Regeneration is a regulative developmental process ubiquitous across all human organs. It functio ...
The Cytoplasmic Domain of the Myelin Po Protein Influences The
... fected CHO cells expressing an abundance of Po with those of control-transfected cells (not expressing Po), we showed, both qualitatively and quantitatively, that Po can behave as a homophilic adhesion molecule (Filbin et al., 1990). This type of assay system, however, cannot be used to address the ...
... fected CHO cells expressing an abundance of Po with those of control-transfected cells (not expressing Po), we showed, both qualitatively and quantitatively, that Po can behave as a homophilic adhesion molecule (Filbin et al., 1990). This type of assay system, however, cannot be used to address the ...
Microbial Cell Factories
... pathways from which novel bio-products, including nano- or micro-structured materials [3537], offer promises in even more diverse applications. Still, many substances and materials of industrial interest are nowadays produced by chemical synthesis, and the number of (recombinant) proteins approved f ...
... pathways from which novel bio-products, including nano- or micro-structured materials [3537], offer promises in even more diverse applications. Still, many substances and materials of industrial interest are nowadays produced by chemical synthesis, and the number of (recombinant) proteins approved f ...
human embryonic stem cells and their clinical relevance
... ROLE OF HUMAN EMBRYONIC STEM CELLS IN TISSUE ENGINEERING Tissue engineering and regeneration Utilize biological substitutes to restore and maintain tissue function. Human embryonic stem cells provide much promise in tissue engineering and regeneration since these cells can act as an inexhaustible in ...
... ROLE OF HUMAN EMBRYONIC STEM CELLS IN TISSUE ENGINEERING Tissue engineering and regeneration Utilize biological substitutes to restore and maintain tissue function. Human embryonic stem cells provide much promise in tissue engineering and regeneration since these cells can act as an inexhaustible in ...
T cell apoptosis and reactive oxygen species
... increased levels of superoxide within cells. For T cells this is evidenced by increased alkalinization of the cell cytosol (which is indicative of increased respiratory activity) rather than increased acidification (which would be evidence of increased glycolytic activity) (10). Thus, mitochondria c ...
... increased levels of superoxide within cells. For T cells this is evidenced by increased alkalinization of the cell cytosol (which is indicative of increased respiratory activity) rather than increased acidification (which would be evidence of increased glycolytic activity) (10). Thus, mitochondria c ...
Regulation of germ line stem cell homeostasis
... that are able to self-renew to maintain their own pool, but also to differentiate into specialized cell types that will ultimately perform a biological function. In the embryo and fetus, stem cell activity is critical for organ development and growth. In adults, stem cells are essential for the main ...
... that are able to self-renew to maintain their own pool, but also to differentiate into specialized cell types that will ultimately perform a biological function. In the embryo and fetus, stem cell activity is critical for organ development and growth. In adults, stem cells are essential for the main ...
Molecular mechanisms involved in colorectal cancer initiation and
... the nature of the founding CRC cell and the mechanisms by which it escapes cell renewal. During 2007, we have generated several DNA constructs to enable the development of animal models that will be used for this purpose. These include the conditional expression in the intestine of oncogenes involve ...
... the nature of the founding CRC cell and the mechanisms by which it escapes cell renewal. During 2007, we have generated several DNA constructs to enable the development of animal models that will be used for this purpose. These include the conditional expression in the intestine of oncogenes involve ...
plants - Georgia Organics
... movement. The stomata of a leaf react to light. They open when light strikes the leaf and close in darkness, causing the plant to lose water during the day. The air temperature and radiant heat from the sun heating a plant’s tissues also affects the rate of transpiration. As the air temperature incr ...
... movement. The stomata of a leaf react to light. They open when light strikes the leaf and close in darkness, causing the plant to lose water during the day. The air temperature and radiant heat from the sun heating a plant’s tissues also affects the rate of transpiration. As the air temperature incr ...
Oxidized Low-Density Lipoprotein Retards the Growth of
... oxLDL may inhibit serum-induced proliferation through a change in the expression or distribution of cell cycle proteins. Expression of cell cycle proteins was examined by using Western blot analysis. In fibroblasts treated with serum and 10 g/mL oxLDL for 24 hours, when cell numbers were reduced by ...
... oxLDL may inhibit serum-induced proliferation through a change in the expression or distribution of cell cycle proteins. Expression of cell cycle proteins was examined by using Western blot analysis. In fibroblasts treated with serum and 10 g/mL oxLDL for 24 hours, when cell numbers were reduced by ...
Rapid analysis of the extracellular matrix protein decorin using the
... near the N-terminus of the core protein and by N-glycosylation at three potential sites (1). It may modify vascular smooth muscle cell function by altering the response to growth factors, such as TGF-β1, and the accumulation of ECM proteins during vascular injury (2–4). Decorin has been shown to inf ...
... near the N-terminus of the core protein and by N-glycosylation at three potential sites (1). It may modify vascular smooth muscle cell function by altering the response to growth factors, such as TGF-β1, and the accumulation of ECM proteins during vascular injury (2–4). Decorin has been shown to inf ...
Responses in Peripheral Lymph Nodes Cells and Naive T Cells
... responses. Exogenously administered DC can prime T cells capable of recognizing and killing tumors in an Ag-specific manner in animal models (1– 4), and have been subsequently incorporated into clinical trials for immunotherapy of cancers (5– 11). Unfortunately, clinical efficacy has been variable. ...
... responses. Exogenously administered DC can prime T cells capable of recognizing and killing tumors in an Ag-specific manner in animal models (1– 4), and have been subsequently incorporated into clinical trials for immunotherapy of cancers (5– 11). Unfortunately, clinical efficacy has been variable. ...
Honey bees are predisposed to win-shift but can learn to win-stay
... often than expected by chance or less often than expected by chance. The ability of bees in nature to choose flowers contingent on the identity of recently visited flowers would have obvious adaptive value. We (Brown & Demas 1994) have shown that memory for previous visits allows previously visited ...
... often than expected by chance or less often than expected by chance. The ability of bees in nature to choose flowers contingent on the identity of recently visited flowers would have obvious adaptive value. We (Brown & Demas 1994) have shown that memory for previous visits allows previously visited ...
Antacids & Acid-Controlling Agents
... ｏ Alters elasticity of mucus-coated bubbles, causing them to break. ｏ Used often, but there are limited data to support effectiveness. ...
... ｏ Alters elasticity of mucus-coated bubbles, causing them to break. ｏ Used often, but there are limited data to support effectiveness. ...
Tissue engineering
Tissue engineering is the use of a combination of cells, engineering and materials methods, and suitable biochemical and physicochemical factors to improve or replace biological functions. While it was once categorized as a sub-field of biomaterials, having grown in scope and importance it can be considered as a field in its own right.While most definitions of tissue engineering cover a broad range of applications, in practice the term is closely associated with applications that repair or replace portions of or whole tissues (i.e., bone, cartilage, blood vessels, bladder, skin, muscle etc.). Often, the tissues involved require certain mechanical and structural properties for proper functioning. The term has also been applied to efforts to perform specific biochemical functions using cells within an artificially-created support system (e.g. an artificial pancreas, or a bio artificial liver). The term regenerative medicine is often used synonymously with tissue engineering, although those involved in regenerative medicine place more emphasis on the use of stem cells or progenitor cells to produce tissues.