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Complement-dependent immune complex-induced - AJP-Lung
Complement-dependent immune complex-induced - AJP-Lung

... and the tail vein was cannulated with a 27-gauge needle for injection of the methacholine challenge. The plethysmograph was sealed, and readings were monitored by computer. Because the box was a closed system, a change in lung volume was represented by a change in box pressure (Pbox) that was measur ...
T cell co-stimulatory receptor CD28 is a primary target for
T cell co-stimulatory receptor CD28 is a primary target for

... Lck-inhibiting kinase Csk from cell lysates (20), and contains a structural motif that might recruit the lipid phosphatase SHIP-1 (27). Using a FRET-based assay (Fig. 2A), we demonstrated that Lck-phosphorylated PD-1 directly binds Shp2 (Fig. 2B), but not Shp1, Csk, SHIP-1, or other SH2 proteins tes ...
The role of lymphatics in renal inflammation
The role of lymphatics in renal inflammation

... number of lymphatics decreases. No lymphatic vessels are present in normal renal medulla [54, 58]. It was hypothesized that fluid from the medullary interstitium moves to lymphatics associated with arcuate or possibly interlobar blood vessels. ...
Dishevelled: at the crossroads of divergent
Dishevelled: at the crossroads of divergent

... are linked, e.g. what the intermediates are between Fz and Dsh, and between Dsh and the small GTPases (see below). 3. Functional studies of Dishevelled 3.1. Molecular features of Dishevelled Despite the genetic requirement for Dsh in wg and polarity signaling, its molecular functions remain unclear. ...
Hydrogen peroxide modulates the dynamic microtubule
Hydrogen peroxide modulates the dynamic microtubule

... against pathogen attack is the production of reactive oxygen species (ROS), including hydrogen peroxide (H2O2) (Lamb & Dixon 1997). The spatial and temporal fluctuations of ROS levels are interpreted as a signal required for plants to respond to pathogens. ROS plays a critical role in induced plant ...
Control Bacterial Quorum Sensing: Its Role in Virulence and
Control Bacterial Quorum Sensing: Its Role in Virulence and

... enterotoxins, superantigens, and urease (SaidSalim et al. 2003; Geisinger et al. 2006). The net result of this QS regulatory cascade is downregulation of surface virulence factors (such as protein A), and up-regulation of secreted virulence factors (such as a-toxin). Most of the effects of QS on reg ...
Dual-topology membrane proteins Escherichia coli  Susanna Seppälä
Dual-topology membrane proteins Escherichia coli Susanna Seppälä

... the translocase into the lipid phase. Biochemistry 46, 15153-15161 Cassel M, Seppälä S, von Heijne G (2008): Confronting fusion-protein based membrane protein topology mapping with reality: the Escherichia coli ClcA H+/Cl- exchange transporter. Journal of Molecular Biology 381, 860866 ...
Evaluation of peptide-mediated nucleic acid delivery
Evaluation of peptide-mediated nucleic acid delivery

... systems as they possess the above mentioned characteristics (28). Furthermore, they are easy to produce, relatively stable, non-toxic and non-immunogenic (2,23). Peptides can be categorized, depending on their function, as: DNA-condensing peptides, which condense nucleic acids, cell-penetrating pept ...
WOX11 and 12 Are Involved in the First-Step Cell
WOX11 and 12 Are Involved in the First-Step Cell

... lateral roots (Celenza et al., 1995), almost completely failed to form callus (Sugimoto et al., 2010). Mutants with loss of function of the Polycomb Repressive Complex 2, which catalyzes genome-wide histone H3 lysine 27 trimethylation (H3K27me3) on chromatin, also showed a block in callus formation ...
Chromatin Fibers Observed In Situ in Frozen Hydrated Sections
Chromatin Fibers Observed In Situ in Frozen Hydrated Sections

... comparison, the same material after GA fixation and conventional epoxy embedding is shown in Fig. 3 b. Both the frozen hydrated and conventionally prepared cells have nuclei filled with chromatin fibers, and, in general, features seen in the epoxy sections have a similar morphology to those present ...
cDNA SEQUENCES OF THE CAPRINE GAMMA DELTA T CELL
cDNA SEQUENCES OF THE CAPRINE GAMMA DELTA T CELL

... a colleague. To get cDNA sequences three strategies were used. Strategy I was used to obtain three clones that corresponded to WC1 SRCR domain d9 through the intracytoplasmic tail sequence. Strategy II was used to obtain 6 clones. A PCR was conducted using SRCR domain b7 through the intracytoplasmic ...
Chapter 4 - A Tour of the Cell 08-09
Chapter 4 - A Tour of the Cell 08-09

... from the environment and dispose of wastes. • The ratio of surface are to volume imposes limits on cell size • Muscle and nerve cells can be very long because they are thin and have more surface area compared ...
PDF
PDF

... associated cells, throughout their transit from the wing disc to the muscle templates (Roy and VijayRaghavan, 1998). It should also be noted that wing morphogenesis and other tissue movements in the developing pupa, generate a highly dynamic landscape in which these cells migrate. The underlying ext ...
Lymphatic vessels and tertiary lymphoid organs
Lymphatic vessels and tertiary lymphoid organs

... inflammation of TLOs. Since edema is a frequent occurrence in acute inflammation, it is likely that LVs associated with that process serve a drainage function. Lymphangiogenesis accompanies acute inflammation with enhanced lymph flow (42). Seeger and colleagues suggest that inflammation occurs befor ...
Cold-Sensitive Cell-Division-Cycle Mutants of Yeast: Isolation, Properties and Pseudoreversion Studies.
Cold-Sensitive Cell-Division-Cycle Mutants of Yeast: Isolation, Properties and Pseudoreversion Studies.

... Two additional new cdc mutations were found as unlinked ts pseudorevertants of a cs cdc mutation (cdc45-1) as described below; since these recessive ts mutations display a medial nuclear division terminal phenotype at their nonpermissive temperature and complement each other and mutations in all oth ...
DNA damage induces nucleoid compaction via the Mre11Rad50
DNA damage induces nucleoid compaction via the Mre11Rad50

... the nucleoid of H. volcanii is diffuse throughout the cytoplasm in unperturbed cells growing in exponential phase, and appears compacted into a smaller area following stresses that damage the genome and/or interfere with its replication. This compaction does not depend on homologous recombination bu ...
The recovery and purification of fermentation products
The recovery and purification of fermentation products

... FIGURE 10.6  Schematic Flow Diagram for Foam Fractionation (Wang & Sinskey, 1970) ...
PDF - ScienceAsia
PDF - ScienceAsia

... and swell out dry cells. Furthermore, the 1 H NMR spectrum of the alcoholic extracts showed some PHA along with grease and lipid cell debris. This indicates that medium chain alcohols can dissolve some of the PHA from the bacterial cell which is probably good for being used as extracting solvents. I ...
CYTOKINE-MEDIATED REGULATION OF BK VIRUS REPLICATION
CYTOKINE-MEDIATED REGULATION OF BK VIRUS REPLICATION

... region transcripts from one genomic strand and late region transcripts from the opposite strand. In addition, the NCCR contains the origin of replication, three TAg binding motifs, and many cellular transcription factor binding sites. The NCCR is the region of greatest variability between different ...
Development of a yeast cell factory for production of
Development of a yeast cell factory for production of

... guidance and support in the projects that I developed through the PhD program at CfB and at the Chalmers University of Technology. Both of you were great collaborators, your advice and support were very helpful. I would like to thank my co-authors Tomas Strucko, Steen Stahlhut, Mette Kristensen, Min ...
Viral Membrane Channels: Role and Function in the Virus Life Cycle
Viral Membrane Channels: Role and Function in the Virus Life Cycle

... on the type of genetic materials they carried, either RNA or DNA viruses. These viral genomes encode structural proteins for virion formation as well as enzymatic and accessory proteins to aid in infection and replication. One common type of accessory protein encoded by most viruses is the viral ion ...
Plant immune and growth receptors share common signalling
Plant immune and growth receptors share common signalling

... mammalian RTK, forms clusters that co-localise with PM nanodomains, and EGFR cluster formation depends on the integrity of the PM lipid composition (Gao et al., 2015). A recent report showed that BRI1 also localises to PM nano- or micro-domains in Arabidopsis roots and that partitioning of BRI1 into ...
Diuretics - AState.edu
Diuretics - AState.edu

... Prompt removal of renal toxins One of the few diuretics that do not remove large amounts of Na+ Can cause hypernatremia ...
Retinoic acid and chick limb bud development
Retinoic acid and chick limb bud development

... Fig. 2. (A) Normal pattern of cartilage elements in embryonic skeleton of chick wing shown in whole mount. The three digits are from anterior (top), 234. (B) Wing skeleton with duplicated pattern of digits following graft of polarizing region tissue to anterior margin of an early bud. Reading from a ...
GO - Buffalo Ontology Site
GO - Buffalo Ontology Site

... http:// ifomis.de ...
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