An Empirical Study of End-User Behaviour in Spreadsheet Error
... 4.1 Overall Results Error Correction Rates Industry-based professional subjects corrected 72% of all seeded errors and student subjects corrected 58% of all seeded errors. The results from Figure 1 show a clear distinction between performances of industry based professionals and students for Rule Vi ...
... 4.1 Overall Results Error Correction Rates Industry-based professional subjects corrected 72% of all seeded errors and student subjects corrected 58% of all seeded errors. The results from Figure 1 show a clear distinction between performances of industry based professionals and students for Rule Vi ...
- Journal of Clinical Investigation
... at least two genetic mutations, one X-linked and the other autosomal recessive (1). More recently, these two forms of the disease have each been subclassified based on the presence or absence of cytochrome b558, a heme protein believed to be a component of the superoxide-generating enzyme, NADPH oxi ...
... at least two genetic mutations, one X-linked and the other autosomal recessive (1). More recently, these two forms of the disease have each been subclassified based on the presence or absence of cytochrome b558, a heme protein believed to be a component of the superoxide-generating enzyme, NADPH oxi ...
STEROIDOGENESIS IN THECA CELLS OF CHICKEN FOLLICLES
... The aim of this study was to assess and compare the steroidogenic response to luteinizing hormone (LH) and follicle-stimulating hormone (FSH) in cells of the theca interna and theca externa isolated from follicles at different stages of maturation. Cells of the theca interna and theca externa isolat ...
... The aim of this study was to assess and compare the steroidogenic response to luteinizing hormone (LH) and follicle-stimulating hormone (FSH) in cells of the theca interna and theca externa isolated from follicles at different stages of maturation. Cells of the theca interna and theca externa isolat ...
Integration of the olfactory code across dendritic
... claws in vivo using two-photon imaging. We used a stochastic genetic approach30 to label single Kenyon cells with both the calcium indicator GCaMP3 (ref. 31) and the anatomical marker myr-tdTomato. tdTomato enabled easy identification of Kenyon cell claws in vivo, whereas GCaMP3 reported the postsyn ...
... claws in vivo using two-photon imaging. We used a stochastic genetic approach30 to label single Kenyon cells with both the calcium indicator GCaMP3 (ref. 31) and the anatomical marker myr-tdTomato. tdTomato enabled easy identification of Kenyon cell claws in vivo, whereas GCaMP3 reported the postsyn ...
Signaling and Communication in Plant Symbiosis - Beck-Shop
... initiate signal transduction following perception of a correctly decorated Nodfactor (Radutoiu et al. 2003). Biochemical studies have subsequently demonstrated NFR1 to be a dual specificity kinase capable of autophosphorylation and phosphorylation of NFR5 (Madsen et al. 2011). In contrast, no kinase ...
... initiate signal transduction following perception of a correctly decorated Nodfactor (Radutoiu et al. 2003). Biochemical studies have subsequently demonstrated NFR1 to be a dual specificity kinase capable of autophosphorylation and phosphorylation of NFR5 (Madsen et al. 2011). In contrast, no kinase ...
Free ISG15 as a dimer generates IL-1β-producing CD8α+
... bioRxiv preprint first posted online Feb. 27, 2017; doi: http://dx.doi.org/10.1101/111658. The copyright holder for this preprint (which was not peer-reviewed) is the author/funder. All rights reserved. No reuse allowed without permission. ...
... bioRxiv preprint first posted online Feb. 27, 2017; doi: http://dx.doi.org/10.1101/111658. The copyright holder for this preprint (which was not peer-reviewed) is the author/funder. All rights reserved. No reuse allowed without permission. ...
Tendon development and musculoskeletal assembly: emerging
... It should be noted that TPCs still develop in Scx −/− mutant mice, suggesting that other genes are required for the initial steps of TPC specification. In Drosophila, the transcription factor Stripe (Sr) specifies TPCs in epidermal segment border cells (Volk and VijayRaghavan, 1994). Flies lacking S ...
... It should be noted that TPCs still develop in Scx −/− mutant mice, suggesting that other genes are required for the initial steps of TPC specification. In Drosophila, the transcription factor Stripe (Sr) specifies TPCs in epidermal segment border cells (Volk and VijayRaghavan, 1994). Flies lacking S ...
Inducible depletion of adult skeletal muscle stem cells impairs the
... skeletal muscle (Murphy et al., 2011; Relaix and Zammit, 2012). We employed 1-2 mm sciatic nerve transection (SNT) to disrupt lower-limb NMJs. This form of surgery leads to complete denervation of adult NMJs. Although delayed, reinnervation as assessed by immunofluorescence (IF) and physiological me ...
... skeletal muscle (Murphy et al., 2011; Relaix and Zammit, 2012). We employed 1-2 mm sciatic nerve transection (SNT) to disrupt lower-limb NMJs. This form of surgery leads to complete denervation of adult NMJs. Although delayed, reinnervation as assessed by immunofluorescence (IF) and physiological me ...
A systematic screen for genes expressed in definitive endoderm by
... in the DE. Importantly, two genes identified, Pyy and 5730521E12Rik, showed exclusive DE expression at early stages of endoderm patterning. Conclusion: The high efficiency of this endoderm screen indicates that our approach can be successfully used to analyze and validate the vast amount of data obt ...
... in the DE. Importantly, two genes identified, Pyy and 5730521E12Rik, showed exclusive DE expression at early stages of endoderm patterning. Conclusion: The high efficiency of this endoderm screen indicates that our approach can be successfully used to analyze and validate the vast amount of data obt ...
SKIP controls lysosome positioning using a composite kinesin
... increase in HA-KLC2 expression compared to co-transfection with GFP (Figure 5A, compare lanes 1,2). Cit-KHC was bound (lane 4) and efficiently depleted from cell extracts (compare lanes 2 and 6) using GFP-TRAP beads. HA-KLC2 co-immunprecipitated with Cit-KHC, but not GFP (lanes 3,4), resulting in it ...
... increase in HA-KLC2 expression compared to co-transfection with GFP (Figure 5A, compare lanes 1,2). Cit-KHC was bound (lane 4) and efficiently depleted from cell extracts (compare lanes 2 and 6) using GFP-TRAP beads. HA-KLC2 co-immunprecipitated with Cit-KHC, but not GFP (lanes 3,4), resulting in it ...
TINOSPORA CORDIFOLIA AFLATOXIN B INDUCED RENAL DAMAGE
... also found in edible tissues, milk and eggs after consumption of contaminated feed by farm animals1, 2. AFB1 is well known to be potent mutagenic, carcinogenic, immunosuppressive, teratogenic and also inhibited several metabolic activities, causing liver, kidney and heart ...
... also found in edible tissues, milk and eggs after consumption of contaminated feed by farm animals1, 2. AFB1 is well known to be potent mutagenic, carcinogenic, immunosuppressive, teratogenic and also inhibited several metabolic activities, causing liver, kidney and heart ...
51:64-72 - Boston College
... as those provided by CO2 imaging chambers [11]. The primary benefit of X. laevis for these studies, however, is its large growth cones, which can be up to 10–30 m in diameter and are perfect for clear and detailed analysis of subcellular cytoskeletal structures and dynamics. There may be no other ve ...
... as those provided by CO2 imaging chambers [11]. The primary benefit of X. laevis for these studies, however, is its large growth cones, which can be up to 10–30 m in diameter and are perfect for clear and detailed analysis of subcellular cytoskeletal structures and dynamics. There may be no other ve ...
Amino acid transporters: roles in amino acid sensing and signalling
... prokaryotes, complex control pathways have been delineated by which the availability of a nutrient may regulate the acquisition, synthesis and utilization of itself (and also other nutrients) as well as modulate general metabolic processes within the cell [1]. In contrast, for higher eukaryotes, it ...
... prokaryotes, complex control pathways have been delineated by which the availability of a nutrient may regulate the acquisition, synthesis and utilization of itself (and also other nutrients) as well as modulate general metabolic processes within the cell [1]. In contrast, for higher eukaryotes, it ...
The glycocalyx of the sperm surface
... NaCl removed a group of ~20 proteins with molecular weights ranging from 10 from 100 kDa (Figure 1, left panel). Subsequent incubation of these proteins with lectins showed that the majority were indeed glycosylated, and that this glycosylation was largely eliminated by pretreatment with N-glycosida ...
... NaCl removed a group of ~20 proteins with molecular weights ranging from 10 from 100 kDa (Figure 1, left panel). Subsequent incubation of these proteins with lectins showed that the majority were indeed glycosylated, and that this glycosylation was largely eliminated by pretreatment with N-glycosida ...
the endocrine system
... INTRODUCTION TO THE ENDOCRINE SYSTEM AND THE PITUITARYHYPOTHALAMIC AXIS ...
... INTRODUCTION TO THE ENDOCRINE SYSTEM AND THE PITUITARYHYPOTHALAMIC AXIS ...
A domain-specific usherin/collagen IV interaction may be required
... binding proteins. Different type III domains may be almost completely dissimilar at the amino acid level and as much as 90% structurally similar (Sharma et al., 1999). Like the LE domains, the fibronectin type III domains tend to be present in a tandem series of variable length, forming a series of ...
... binding proteins. Different type III domains may be almost completely dissimilar at the amino acid level and as much as 90% structurally similar (Sharma et al., 1999). Like the LE domains, the fibronectin type III domains tend to be present in a tandem series of variable length, forming a series of ...
Chloroplast DNA replication is regulated by the redox state
... reinhardtii using a light and dark cycle, and then one population was cultured in the same light and dark cycle while the other was cultured under continuous light. The nuclear and chloroplast DNA levels were examined by qPCR of the RBCS gene (the nuclear genome) and the rbcL gene (the chloroplast g ...
... reinhardtii using a light and dark cycle, and then one population was cultured in the same light and dark cycle while the other was cultured under continuous light. The nuclear and chloroplast DNA levels were examined by qPCR of the RBCS gene (the nuclear genome) and the rbcL gene (the chloroplast g ...
VIRUS-LIKE PARTICLES ELICIT ENHANCED IMMUNITY TO
... model antigen, and influenza virus in the lungs and TBLNs significantly earlier than controls. Additionally, VLP-primed CD11c+ cells that trafficked in a CCR2-dependent manner, and upregulated T cell co-stimulatory molecules were associated with enhanced viral clearance. Influenza-specific CD4+ T ce ...
... model antigen, and influenza virus in the lungs and TBLNs significantly earlier than controls. Additionally, VLP-primed CD11c+ cells that trafficked in a CCR2-dependent manner, and upregulated T cell co-stimulatory molecules were associated with enhanced viral clearance. Influenza-specific CD4+ T ce ...
The ribosome — a macromolecular machine par excellence
... from the A site to the P site, respectively. The interaction of these factors with the ribosome involves multiple binding sites on both subunits, and requires energy from GTP hydrolysis. ...
... from the A site to the P site, respectively. The interaction of these factors with the ribosome involves multiple binding sites on both subunits, and requires energy from GTP hydrolysis. ...
- Wiley Online Library
... capable of synthesizing full-length proteins in vitro, suggesting that these RNA modifications are not fundamental for all basic steps of protein biosynthesis.15 However, some methylated nucleotides have been implicated in fine-tuning translation initiation and decoding fidelity,14 and several pseudour ...
... capable of synthesizing full-length proteins in vitro, suggesting that these RNA modifications are not fundamental for all basic steps of protein biosynthesis.15 However, some methylated nucleotides have been implicated in fine-tuning translation initiation and decoding fidelity,14 and several pseudour ...
phosphatases and differentiation of the golgi apparatus
... Both MnCl2 and MgCl2 were tested as activators. Novikoff et al. (1962) suggested some superiority of MnCl2 at least for the ER and it proved to be slightly better in these experiments; hence it was used in the experiments from which data are reported. All reaction mixture solutions were made up fres ...
... Both MnCl2 and MgCl2 were tested as activators. Novikoff et al. (1962) suggested some superiority of MnCl2 at least for the ER and it proved to be slightly better in these experiments; hence it was used in the experiments from which data are reported. All reaction mixture solutions were made up fres ...
Cell Alloimmunization Hemin Controls T Cell Polarization in Sickle
... higher circulating Th1 (IFN-g+) cytokines in chronically transfused SCD patients with alloantibodies as compared with those without alloantibodies. Because monocytes play a critical role in polarization of T cell subsets and participate in clearance of transfused RBCs, we tested the hypothesis that ...
... higher circulating Th1 (IFN-g+) cytokines in chronically transfused SCD patients with alloantibodies as compared with those without alloantibodies. Because monocytes play a critical role in polarization of T cell subsets and participate in clearance of transfused RBCs, we tested the hypothesis that ...
Copyright Information of the Article Published Online TITLE Dynamic
... such as other connective tissue cells, but also are involved in force production. In the tissue remodelling phase of wound closure, integrin-mediated interactions between MFs and type I collagen result in scar tissue formation. The tumour stroma in oral cancer actively recruits various cell types in ...
... such as other connective tissue cells, but also are involved in force production. In the tissue remodelling phase of wound closure, integrin-mediated interactions between MFs and type I collagen result in scar tissue formation. The tumour stroma in oral cancer actively recruits various cell types in ...
LvNotch positions the ectoderm-endoderm boundary
... were fertilized in 5 mM p-aminobenzoic acid (PABA), which was washed out immediately after fertilization. Treatment with PABA softened the fertilization membrane, allowing the embryos to be freed from the membranes, which adhered to the injection dish. To lineage and identify injected blastomeres, f ...
... were fertilized in 5 mM p-aminobenzoic acid (PABA), which was washed out immediately after fertilization. Treatment with PABA softened the fertilization membrane, allowing the embryos to be freed from the membranes, which adhered to the injection dish. To lineage and identify injected blastomeres, f ...
Mechanisms of dorsal-ventral axis determination in
... the nuclear gradient of dorsal protein, the morphogen of the dorsal-ventral axis. Here, I analyse the dorsal protein distribution and the expression of zygotic dorsalventral genes in Toll embryos that have been injected with wild-type cytoplasm under a variety of different injection conditions. Inje ...
... the nuclear gradient of dorsal protein, the morphogen of the dorsal-ventral axis. Here, I analyse the dorsal protein distribution and the expression of zygotic dorsalventral genes in Toll embryos that have been injected with wild-type cytoplasm under a variety of different injection conditions. Inje ...