Cell adhesion and cell mechanics during zebrafish
... Fig. 1.2 Cell adhesion, cortex tension and membrane mechanics influence cell behavior A: Schematic representation and summary of the cell mechanical problems studied during this thesis. Cells adhere via cell adhesion molecules (grey) and separate according to their adhesion strength and cortical act ...
... Fig. 1.2 Cell adhesion, cortex tension and membrane mechanics influence cell behavior A: Schematic representation and summary of the cell mechanical problems studied during this thesis. Cells adhere via cell adhesion molecules (grey) and separate according to their adhesion strength and cortical act ...
Spatiotemporal Patterns of Expression of NGF and the Low
... mandible of an E15.5 embryo hybridized to ~75 MX=Rantisense riboprobe. Note the extensive ~75~~~ expression throughout the mesenchyme of the maxillary process. G, Dark-field photomicrograph of section adjacent to F and hybridized to NGF antisense riboprobe. Note transcripts are confined to the epith ...
... mandible of an E15.5 embryo hybridized to ~75 MX=Rantisense riboprobe. Note the extensive ~75~~~ expression throughout the mesenchyme of the maxillary process. G, Dark-field photomicrograph of section adjacent to F and hybridized to NGF antisense riboprobe. Note transcripts are confined to the epith ...
Bile Formation: a Concerted Action of Membrane
... News Physiol. Sci. • Volume 15 • February 2000 ...
... News Physiol. Sci. • Volume 15 • February 2000 ...
Chapter 16—Probes for Endocytosis, Receptors and Ion Channels
... 16.1 Probes for Following Receptor Binding and Phagocytosis The plasma membrane defines the inside and outside of the cell. It not only encloses the cytosol to maintain the intracellular environment but also serves as a formidable barrier to the extracellular environment. Because cells require input ...
... 16.1 Probes for Following Receptor Binding and Phagocytosis The plasma membrane defines the inside and outside of the cell. It not only encloses the cytosol to maintain the intracellular environment but also serves as a formidable barrier to the extracellular environment. Because cells require input ...
Quantitative determinants of aerobic glycolysis identify flux through
... converts glucose step-by-step into a simpler chemical called pyruvate. Pyruvate is then normally transported into structures within the cell called mitochondria, where it is further broken down using oxygen to release more energy. However, in cells that are rapidly dividing, pyruvate is converted in ...
... converts glucose step-by-step into a simpler chemical called pyruvate. Pyruvate is then normally transported into structures within the cell called mitochondria, where it is further broken down using oxygen to release more energy. However, in cells that are rapidly dividing, pyruvate is converted in ...
Bound by Fate: The Role of Reactive Oxygen
... described for numerous processes downstream of RLK activation. These processes range from the recognition of microbeassociated molecular patterns (MAMPs) and host-derived damage-associated molecular patterns (DAMPs) to the control of plant development (Table 1). The Arabidopsis genome encodes 10 RBO ...
... described for numerous processes downstream of RLK activation. These processes range from the recognition of microbeassociated molecular patterns (MAMPs) and host-derived damage-associated molecular patterns (DAMPs) to the control of plant development (Table 1). The Arabidopsis genome encodes 10 RBO ...
Whole-tree and tension wood-associated expression profiles of microRNAs in Eucalyptus Grant R. McNair
... components, in this case miRNAs. In order to develop a more complete understanding of miRNA function in wood formation, one should also take into account the complexities of plant development as a whole. The aim of this M.Sc study is the determination of miRNA abundance patterns at the whole tree le ...
... components, in this case miRNAs. In order to develop a more complete understanding of miRNA function in wood formation, one should also take into account the complexities of plant development as a whole. The aim of this M.Sc study is the determination of miRNA abundance patterns at the whole tree le ...
An ancestral stomatal patterning module revealed in
... epidermal cell (Fig. 2C,D). Quantification confirmed an increased number of stomata per capsule in the sporophytes of three independently generated ppepf1 knockout lines (Fig. 2E). Expression analysis confirmed the absence (lines ppepf1-2, ppepf1-3) or greatly decreased transcript level ( ppepf1-1) ...
... epidermal cell (Fig. 2C,D). Quantification confirmed an increased number of stomata per capsule in the sporophytes of three independently generated ppepf1 knockout lines (Fig. 2E). Expression analysis confirmed the absence (lines ppepf1-2, ppepf1-3) or greatly decreased transcript level ( ppepf1-1) ...
The head organizer in Hydra
... An adult Hydra has the shape of a cylindrical shell consisting of two tissue layers: an ectoderm and an endoderm that make up the head, body column and basal disk (Fig. 1). An organizer is usually associated with the early stages of the development of an embryo. As described above, an adult Hydra ha ...
... An adult Hydra has the shape of a cylindrical shell consisting of two tissue layers: an ectoderm and an endoderm that make up the head, body column and basal disk (Fig. 1). An organizer is usually associated with the early stages of the development of an embryo. As described above, an adult Hydra ha ...
Protection by chlorpromazine, albumin and bivalent cations against
... current maintained across it. The magnitudes of these resistive pulses are displayed in the form of spectra (256-channel histograms), the modal peaks and other characteristics of which are analysed by computer. In the present study, a cylindrical, 50 µm long and 50 µm in diameter, orifice was used i ...
... current maintained across it. The magnitudes of these resistive pulses are displayed in the form of spectra (256-channel histograms), the modal peaks and other characteristics of which are analysed by computer. In the present study, a cylindrical, 50 µm long and 50 µm in diameter, orifice was used i ...
The Membrane Steps of Bacterial Cell Wall Synthesis as Antibiotic
... lipid was required for the synthesis of Lipid I, neither was required for the exchange reaction between UMP and UDP-Mpp [40]. The lack of structural information at the time limited the understanding of the mechanism of MraY, which made the reasons for the dependence on polar lipids unclear. Recent o ...
... lipid was required for the synthesis of Lipid I, neither was required for the exchange reaction between UMP and UDP-Mpp [40]. The lack of structural information at the time limited the understanding of the mechanism of MraY, which made the reasons for the dependence on polar lipids unclear. Recent o ...
PDF + SI - The Journal of Immunology
... defense against inflammatory bowel diseases, autoimmune diseases, allergies, infections, and cancers. Therefore, clarification of the mechanism of IL-10 and IL-12 production by macrophages and dendritic cells in response to probiotics is expected to lead to a greater understanding of their immunoreg ...
... defense against inflammatory bowel diseases, autoimmune diseases, allergies, infections, and cancers. Therefore, clarification of the mechanism of IL-10 and IL-12 production by macrophages and dendritic cells in response to probiotics is expected to lead to a greater understanding of their immunoreg ...
PDF
... branching. Specifically, we chose to carry out RNAi screens to identify genes that regulate the branching of PVD neuron dendrites in C. elegans. PVD neurons are bilaterally symmetric nociceptors that respond to harsh mechanical stimuli and cold temperatures (Chatzigeorgiou et al., 2010; Way and Chal ...
... branching. Specifically, we chose to carry out RNAi screens to identify genes that regulate the branching of PVD neuron dendrites in C. elegans. PVD neurons are bilaterally symmetric nociceptors that respond to harsh mechanical stimuli and cold temperatures (Chatzigeorgiou et al., 2010; Way and Chal ...
www.drmichaellevin.org
... ABSTRACT Recent experiments have suggested a pathway of genes that regulate left-right asymmetry in vertebrate embryogenesis. The most downstream member of this cascade is nodal (XNR-1 in frogs), which is expressed in the left-side lateral mesoderm. Previous work in the chick [Levin, 1998] suggests ...
... ABSTRACT Recent experiments have suggested a pathway of genes that regulate left-right asymmetry in vertebrate embryogenesis. The most downstream member of this cascade is nodal (XNR-1 in frogs), which is expressed in the left-side lateral mesoderm. Previous work in the chick [Levin, 1998] suggests ...
Two lineage boundaries coordinate vertebrate apical ectodermal
... found only within the AER and not also in the neighboring ectoderm. In a few exceptions, cells were seen in immediately adjacent ventral ectoderm (3/13) (Fig. 2H), and in one case in dorsal ectoderm (1/9). This suggested that additional borders might be present between the AER and the adjacent ectod ...
... found only within the AER and not also in the neighboring ectoderm. In a few exceptions, cells were seen in immediately adjacent ventral ectoderm (3/13) (Fig. 2H), and in one case in dorsal ectoderm (1/9). This suggested that additional borders might be present between the AER and the adjacent ectod ...
DOMAIN-BASED APPROACHES TO
... this research. Then, the domain complexity of proteins was analysed on a comprehensive basis. Our results showed that bacterial and archaeal proteins are as complex as eukaryotic proteins in domain abundance, but more promiscuous. Proteins emerged in early stage are also more promiscuous, but with l ...
... this research. Then, the domain complexity of proteins was analysed on a comprehensive basis. Our results showed that bacterial and archaeal proteins are as complex as eukaryotic proteins in domain abundance, but more promiscuous. Proteins emerged in early stage are also more promiscuous, but with l ...
RNA Polymerase I-Specific Subunit CAST/hPAF49 Has a Role in the
... PAF53 (UltimatORF clone IOH27877; Invitrogen) and human CAST/hPAF49 were cloned in pBAD-DEST49 Gateway vector (Invitrogen). Proteins were expressed in Escherichia coli TOP10 cells (Invitrogen) according to the manufacturer’s instructions (a 0.02% final concentration of arabinose was used for inducti ...
... PAF53 (UltimatORF clone IOH27877; Invitrogen) and human CAST/hPAF49 were cloned in pBAD-DEST49 Gateway vector (Invitrogen). Proteins were expressed in Escherichia coli TOP10 cells (Invitrogen) according to the manufacturer’s instructions (a 0.02% final concentration of arabinose was used for inducti ...
Characterization of the effects of antiepileptic drugs on bone
... required to ensure an adequate skeletal tissue structure, and it involves resorption of old bone and formation of new bone tissue. It is reported that treatment with antiepileptic drugs (AEDs) can elicit alterations in skeletal structure, in particular in bone mineral density. Nevertheless, the know ...
... required to ensure an adequate skeletal tissue structure, and it involves resorption of old bone and formation of new bone tissue. It is reported that treatment with antiepileptic drugs (AEDs) can elicit alterations in skeletal structure, in particular in bone mineral density. Nevertheless, the know ...
Cenp-A Presence in Drosophila - Institute of Molecular Life Sciences
... crucial component of the epigenetic centromere mark. Hence, maintenance of the amount and chromosomal location of CenH3 during mitotic proliferation is important. Interestingly, CenH3 may have different roles during meiosis and the onset of embryogenesis. In gametes of Caenorhabditis elegans, and po ...
... crucial component of the epigenetic centromere mark. Hence, maintenance of the amount and chromosomal location of CenH3 during mitotic proliferation is important. Interestingly, CenH3 may have different roles during meiosis and the onset of embryogenesis. In gametes of Caenorhabditis elegans, and po ...
Accepted version - QMRO Home - Queen Mary University of London
... Recent pre-clinical and clinical research has suggested that transplantation of bone marrowderived mesenchymal stromal cells (MSCs) is a promising new approach for the treatment of heart failure.[1] Although cardiomyogenic differentiation of these cells in vivo is limited, MSCs are able to induce th ...
... Recent pre-clinical and clinical research has suggested that transplantation of bone marrowderived mesenchymal stromal cells (MSCs) is a promising new approach for the treatment of heart failure.[1] Although cardiomyogenic differentiation of these cells in vivo is limited, MSCs are able to induce th ...
The Populus homeobox gene ARBORKNOX2 regulates
... Frugis et al., 2001). In Arabidopsis, BP overexpression plants have impaired lignin deposition in inflorescence stems during primary growth, whereas bp plants show ectopic lignification in the interfascicular region of the inflorescence stem (Mele et al., 2003). Importantly, the expression of key ce ...
... Frugis et al., 2001). In Arabidopsis, BP overexpression plants have impaired lignin deposition in inflorescence stems during primary growth, whereas bp plants show ectopic lignification in the interfascicular region of the inflorescence stem (Mele et al., 2003). Importantly, the expression of key ce ...
- Nottingham ePrints
... Pourquie et al., 1996; Tajbakhsh et al., 1998). However it is clear that the signalling events that control myogenesis in developing limbs are distinct from those in somites. It has been suggested that limb myoblasts differentiate via a default pathway once they escape inhibitory BMP (Amthor et al. ...
... Pourquie et al., 1996; Tajbakhsh et al., 1998). However it is clear that the signalling events that control myogenesis in developing limbs are distinct from those in somites. It has been suggested that limb myoblasts differentiate via a default pathway once they escape inhibitory BMP (Amthor et al. ...
thesis - BORA
... §1.2.1 Notochord signals to adjacent tissues ...................................................................... 3 §1.2.2 Cell differentiation determines the biomechanical properties of the embryonic notochord ....................................................................................... ...
... §1.2.1 Notochord signals to adjacent tissues ...................................................................... 3 §1.2.2 Cell differentiation determines the biomechanical properties of the embryonic notochord ....................................................................................... ...
Factor of Transcription by Upstream Binding CAST/hPAF49 Has a
... PAF53 (UltimatORF clone IOH27877; Invitrogen) and human CAST/hPAF49 were cloned in pBAD-DEST49 Gateway vector (Invitrogen). Proteins were expressed in Escherichia coli TOP10 cells (Invitrogen) according to the manufacturer’s instructions (a 0.02% final concentration of arabinose was used for inducti ...
... PAF53 (UltimatORF clone IOH27877; Invitrogen) and human CAST/hPAF49 were cloned in pBAD-DEST49 Gateway vector (Invitrogen). Proteins were expressed in Escherichia coli TOP10 cells (Invitrogen) according to the manufacturer’s instructions (a 0.02% final concentration of arabinose was used for inducti ...
A three-stage model of Golgi structure and function
... separation enables the cell to optimize the pH, ion composition, and substrate concentrations for each set of enzymes. Moreover, enzyme separation may sometimes be essential to prevent two reactions from competing. For example, mammalian lysosomal hydrolases are modified with a mannose 6-phosphate s ...
... separation enables the cell to optimize the pH, ion composition, and substrate concentrations for each set of enzymes. Moreover, enzyme separation may sometimes be essential to prevent two reactions from competing. For example, mammalian lysosomal hydrolases are modified with a mannose 6-phosphate s ...