Analysis of tissue flow patterns during primitive streak formation in
... To quantitatively analyse tissue movements during streak formation, we processed time series of brightfield images of developing chick embryos in EC culture to obtain vector velocity fields for of the entire epiblast. We combined this information with DiI labelling of small groups of cells in the ep ...
... To quantitatively analyse tissue movements during streak formation, we processed time series of brightfield images of developing chick embryos in EC culture to obtain vector velocity fields for of the entire epiblast. We combined this information with DiI labelling of small groups of cells in the ep ...
... color of the flowers, seeds, fruits and leaves of plants [1]. Anthocyanins belong to the group of flavonoids and are glycosides of anthocyanidin, i.e. they consist of an anthocyanidin molecule which is joins to a sugar molecule by a glycosidic bond (Figure 1) [2]. These compounds are mainly used as ...
161021 NGF revised Manuscript with figs
... G Iadanza2,3, Neil A Ranson2,3, Alison E Ashcroft2,3, Alistair D Kippen1,ǂ, Tristan J Vaughan1, Sheena E ...
... G Iadanza2,3, Neil A Ranson2,3, Alison E Ashcroft2,3, Alistair D Kippen1,ǂ, Tristan J Vaughan1, Sheena E ...
as a PDF
... post-irradiation (not shown) or in control mice (0 Gy). Apoptotic cells were primarily bronchiolar epithelial cells. Further investigations are ongoing to define additional cell type/s that may undergo apoptosis in the lumen. Moreover, we found increased levels of albumin in the BALF of irradiated W ...
... post-irradiation (not shown) or in control mice (0 Gy). Apoptotic cells were primarily bronchiolar epithelial cells. Further investigations are ongoing to define additional cell type/s that may undergo apoptosis in the lumen. Moreover, we found increased levels of albumin in the BALF of irradiated W ...
From DEPARTMENT OF MEDICAL
... The degeneration of midbrain dopaminergic (mDA) neurons accounts for some of the main motor symptoms of Parkinson’s disease (PD). Efforts during the last decades have focused on understanding how mDA neurons are generated and maintained with the hope of developing novel stem cell-based replacement t ...
... The degeneration of midbrain dopaminergic (mDA) neurons accounts for some of the main motor symptoms of Parkinson’s disease (PD). Efforts during the last decades have focused on understanding how mDA neurons are generated and maintained with the hope of developing novel stem cell-based replacement t ...
PHAGOLYSOSOME FORMATION IN NORMAL AND
... (Gilford Instrument Laboratories, Inc., Oberlin, Ohio) at 267 nm, as described by Weisman and Korn (9), to yield a quantitative estimate of PVT concentration. Uptake of PVT, normalized for cell protein, was determined for the period during which uptake was linear (between 20 and 60 min after additio ...
... (Gilford Instrument Laboratories, Inc., Oberlin, Ohio) at 267 nm, as described by Weisman and Korn (9), to yield a quantitative estimate of PVT concentration. Uptake of PVT, normalized for cell protein, was determined for the period during which uptake was linear (between 20 and 60 min after additio ...
The role of the cytoskeleton in the polarized growth of
... 20 pM or higher, cells neither germinated nor swelled (data not shown). Inhibition of germination by CA was reversed when the cells were washed free of CA. In an experiment where yeast cells that had been incubated in GI medium with 5 pM CA for 30 min were transferred to CA-free GI medium, 96% of th ...
... 20 pM or higher, cells neither germinated nor swelled (data not shown). Inhibition of germination by CA was reversed when the cells were washed free of CA. In an experiment where yeast cells that had been incubated in GI medium with 5 pM CA for 30 min were transferred to CA-free GI medium, 96% of th ...
Signaling
... Receptor/Ligand Binds to promoter elements in DNA and regulates transcription Cortisol Receptor is located in the cytosol ...
... Receptor/Ligand Binds to promoter elements in DNA and regulates transcription Cortisol Receptor is located in the cytosol ...
Chloride Channels Regulate HIT Cell Volume but Cannot
... (2) and that anion substitution significantly modifies insulin secretion (2,3). In addition, anion channel blockers have been shown to strongly modulate glucose-induced islet electrical activity (4). Most of these earlier studies of the effects of anions on islet physiology presumed that anion trans ...
... (2) and that anion substitution significantly modifies insulin secretion (2,3). In addition, anion channel blockers have been shown to strongly modulate glucose-induced islet electrical activity (4). Most of these earlier studies of the effects of anions on islet physiology presumed that anion trans ...
Biogenesis of hepatitis C virus envelope glycoproteins
... catalysed by a host signal peptidase localized in the endoplasmic reticulum (ER) (reviewed in Reed & Rice, 2000). Although cleavages at the N termini of E1 and E2 proceed to completion rapidly after translation (Dubuisson et al., 1994, 2000), cleavage is delayed at the p7\NS2 site and, at least for ...
... catalysed by a host signal peptidase localized in the endoplasmic reticulum (ER) (reviewed in Reed & Rice, 2000). Although cleavages at the N termini of E1 and E2 proceed to completion rapidly after translation (Dubuisson et al., 1994, 2000), cleavage is delayed at the p7\NS2 site and, at least for ...
development through auxin-induced cytokinin oxidase activity
... treatment (Fig. 2A, insets). To assess the effects of low R/FR on auxin signaling in leaf primordia at a later developmental stage, DR5⬋GUS seedlings were grown for 6 d in high R/FR, and then maintained in high R/FR or transferred to low R/FR for 4 h. At this stage, the initiation of the leaf lamina ...
... treatment (Fig. 2A, insets). To assess the effects of low R/FR on auxin signaling in leaf primordia at a later developmental stage, DR5⬋GUS seedlings were grown for 6 d in high R/FR, and then maintained in high R/FR or transferred to low R/FR for 4 h. At this stage, the initiation of the leaf lamina ...
Synthesis of a Viral Protein with Molecular
... healthy individuals and patients with neoplastic diseases (23). However, it was convincingly shown that these anti-gp70 anti bodies are formed in response to cellular modification of glycoproteins rather than as a consequence of exposure to virus (2, 22). Human sera in those studies appeared not to ...
... healthy individuals and patients with neoplastic diseases (23). However, it was convincingly shown that these anti-gp70 anti bodies are formed in response to cellular modification of glycoproteins rather than as a consequence of exposure to virus (2, 22). Human sera in those studies appeared not to ...
Growth Factors Are Released by Mechanically Wounded
... Mechanical trauma of tissues in vivo results both in irreversible and transient disruption of cell plasma membranes, while organellar membranes within dead or within wounded but surviving cells, appear not to be disrupted (McNeil and Ito, 1989; McNeil, P. L., S. Ito, and R. Chen, unpublished observa ...
... Mechanical trauma of tissues in vivo results both in irreversible and transient disruption of cell plasma membranes, while organellar membranes within dead or within wounded but surviving cells, appear not to be disrupted (McNeil and Ito, 1989; McNeil, P. L., S. Ito, and R. Chen, unpublished observa ...
A New Model of the Human Atrial Myocyte with Variable T
... Atrial tissues were obtained from 16 consenting patients in sinus rhythm undergoing cardiac surgery. Procedures and experiments involving human atrial cells were approved by the West of Scotland Research Ethics Service (REC: 99MC002). Tissues were fixed in 2% paraformaldehyde then cryoprotected over ...
... Atrial tissues were obtained from 16 consenting patients in sinus rhythm undergoing cardiac surgery. Procedures and experiments involving human atrial cells were approved by the West of Scotland Research Ethics Service (REC: 99MC002). Tissues were fixed in 2% paraformaldehyde then cryoprotected over ...
Sample pages 2 PDF
... Materials of construction of the human body include proteins, polysaccharides, lipids, and nucleic acids. These macromolecules not only compose the protein networks that form the scaffold of both mineralized and nonmineralized tissues, but they also make up the structural materials within the cell i ...
... Materials of construction of the human body include proteins, polysaccharides, lipids, and nucleic acids. These macromolecules not only compose the protein networks that form the scaffold of both mineralized and nonmineralized tissues, but they also make up the structural materials within the cell i ...
Full Text - Molecular Biology and Evolution
... P ¼ 2.881011; r ¼ 0.712). A simple protein–protein BLAST (BLASTp) search (Altschul et al. 1990) against the full nonredundant (nr) NCBI protein database confirms these findings (supplementary fig. S1, Supplementary Material online). This dramatic reduction in the conservation of membrane proteins ...
... P ¼ 2.881011; r ¼ 0.712). A simple protein–protein BLAST (BLASTp) search (Altschul et al. 1990) against the full nonredundant (nr) NCBI protein database confirms these findings (supplementary fig. S1, Supplementary Material online). This dramatic reduction in the conservation of membrane proteins ...
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... reviewed Williams et al. (2004). Aflatoxin B1 (AFB1) is a potent carcinogen and can be metabolised in vivo to Aflatoxin M1 9AFM1) which, in turn, can be found in milk and other animal products Prandini et al. (2009). Biological decontamination of mycotoxins using microorganisms is one of the well-kn ...
... reviewed Williams et al. (2004). Aflatoxin B1 (AFB1) is a potent carcinogen and can be metabolised in vivo to Aflatoxin M1 9AFM1) which, in turn, can be found in milk and other animal products Prandini et al. (2009). Biological decontamination of mycotoxins using microorganisms is one of the well-kn ...
The Arabidopsis repressor of light signaling SPA1
... 1C). In developing leaves, SPA1 mRNA levels were lower in epidermal tissue than in inner tissues (Fig. 1I). The spatial SPA1 transcript accumulation was very similar in the spa mutant backgrounds used in the studies described below (see Fig. S1 in the supplementary material). This ubiquitous express ...
... 1C). In developing leaves, SPA1 mRNA levels were lower in epidermal tissue than in inner tissues (Fig. 1I). The spatial SPA1 transcript accumulation was very similar in the spa mutant backgrounds used in the studies described below (see Fig. S1 in the supplementary material). This ubiquitous express ...
HnRNP C1/C2 May Regulate Exon 7 Splicing in the Spinal Muscular
... sequences. They showed that depletion of hnRNP A1 significantly enhanced SMN2 exon 7 inclusion. These two models are not necessarily incompatible because both the loss of an SF2/ASF-specific ESE and the simultaneous creation of an hnRNP A1-binding site could contribute to SMN2 exon 7 skipping. Indee ...
... sequences. They showed that depletion of hnRNP A1 significantly enhanced SMN2 exon 7 inclusion. These two models are not necessarily incompatible because both the loss of an SF2/ASF-specific ESE and the simultaneous creation of an hnRNP A1-binding site could contribute to SMN2 exon 7 skipping. Indee ...
Microbial Immune Suppression Mediated by Direct Engagement of Inhibitory Fc Receptor
... and cellular proliferation (18, 19) occur through recruitment of SHIP as its effector molecule. Evidence from several research groups has shown that passive administration of IgG1 protective Abs to GXM can reverse the immune suppressive effects exerted by GXM (20 –22). There are multiple mechanisms ...
... and cellular proliferation (18, 19) occur through recruitment of SHIP as its effector molecule. Evidence from several research groups has shown that passive administration of IgG1 protective Abs to GXM can reverse the immune suppressive effects exerted by GXM (20 –22). There are multiple mechanisms ...
Variations of bacterial-specific activity with cell size and nucleic acid
... (Marie et al. 1997, Lebaron et al. 1998b). In a recent study, it was shown that HNA cells were responsible for most of the total bacterial production in various aquatic environments and that the average specific activity (SA) of these HNA cells varied greatly depending on the trophic status of the e ...
... (Marie et al. 1997, Lebaron et al. 1998b). In a recent study, it was shown that HNA cells were responsible for most of the total bacterial production in various aquatic environments and that the average specific activity (SA) of these HNA cells varied greatly depending on the trophic status of the e ...
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... for surviving in the dry aerial environment. A detailed understanding of the structure, composition, and development of moss cell walls can contribute to our understanding of not only the evolution of overall cell wall complexity, but also the differences that have evolved in response to selection f ...
... for surviving in the dry aerial environment. A detailed understanding of the structure, composition, and development of moss cell walls can contribute to our understanding of not only the evolution of overall cell wall complexity, but also the differences that have evolved in response to selection f ...
Я-Amyloid-Induced Synthesis of the Ganglioside Gd3 Is a Requisite
... higher than in control cultures, 16 hr after the addition of AP(25–35) (Fig. 1 A,B). In Figure 2 A,B,D, double-fluorescence analysis of GD3 ( green) and nuclear chromatin (red) showed few neurons expressing GD3 in control cultures or in cultures exposed to the reverse peptide AP(35–25). Nearly all ...
... higher than in control cultures, 16 hr after the addition of AP(25–35) (Fig. 1 A,B). In Figure 2 A,B,D, double-fluorescence analysis of GD3 ( green) and nuclear chromatin (red) showed few neurons expressing GD3 in control cultures or in cultures exposed to the reverse peptide AP(35–25). Nearly all ...
