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Lung cysts in Birt-Hogg-Dubé syndrome: Histopathological
Lung cysts in Birt-Hogg-Dubé syndrome: Histopathological

... Expression of FLCN in the lung To clarify whether FLCN, the protein encoded by BHD gene, is detectable in the lung, immunostaining was performed. According to a previous study using in situ hybridization, BHD mRNA was shown to be expressed in alveolar macrophages, stromal fibroblasts and pneumocytes ...
A Simple 1-D Physical Model for the Crawling Nematode Sperm Cell
A Simple 1-D Physical Model for the Crawling Nematode Sperm Cell

... involved in many different aspects of cell behavior and require a host of accessory proteins. This complexity has frustrated interpretation of many experiments. Because of that, simple and specialized cells, like the sperm of a nematode (Ascaris suum), have attracted the attention of experimentalist ...
Meristem-Specific Suppression of Mitosis and a
Meristem-Specific Suppression of Mitosis and a

... to influence gene expression and behavior of soil-borne pathogens and symbionts is the basis for the hypothesis that they protect plant health by affecting the ecology of the rhizosphere surrounding vulnerable young root tips (for review, see Hawes and Brigham, 1992; Hawes et al., 1998). We have ter ...
MBG404_LS_11
MBG404_LS_11

... All pathways are networks of interactions, however not all networks are pathways! ...
Discs large 5, an Essential Gene in Drosophila, Regulates Egg
Discs large 5, an Essential Gene in Drosophila, Regulates Egg

... Polymorphisms in Dlg5 interfere with its scaffolding function and are associated with inflammatory bowel disease in humans (Stoll et al. 2004). Despite this association, little is known about Dlg5. Drosophila Dlg5 and human Dlg5 (Discs large 5 homolog) share the same general domain architecture, with ...
FREE Sample Here
FREE Sample Here

... Ans: Living organisms (1) are chemically complex and highly organized; (2) extract, transform, and use energy from their environment; (3) have the capacity to precisely self-replicate and self-assemble; (4) exploit a chemical interplay with their environment; (5) possess programmatically defined fun ...
consequences for amino acid starvation.
consequences for amino acid starvation.

... from a complex network of gene control pathways, but instead emerges naturally from the interplay between different processes via the supply and demand of different resources. This represents a new paradigm for gene regulation: that of community based control of a complex system. The amino acids whi ...
NUCLEAR AND CYTOPLASMIC STAINING
NUCLEAR AND CYTOPLASMIC STAINING

... enzymes and the structure-linked is depend on their lytic potential. The single unit membrane of the lysosome acts as a barrier between the enzymes enclosed in the lysosome and the external substrate. The activity of the enzymes contained in lysosomes is limited or nil unless the vesicle in which th ...
TRANSPORT OF SODIUM, POTASSIUM, AND CALCIUM ACROSS
TRANSPORT OF SODIUM, POTASSIUM, AND CALCIUM ACROSS

... however, a transient decrease in the steady-state level of cell-associated 45Ca was induced by FMLP. The curves relating the concentration of FMLP to its effects on cation fluxes are very similar to those found for its enhancement of migration. The presence of actin- and myosin-like proteins has bee ...
IF-3
IF-3

...  Each subunit has several active centers, concentrated in the translational domain of the ribosome where proteins are synthesized. Proteins leave the ribosome through the exit domain, which can associate with a membrane. The major active sites are the P and A sites, the E site, the EF-Tu and EF-G ...
Functional coupling of microtubules to membranes
Functional coupling of microtubules to membranes

... where such rapid changes of direction are triggered by the specific recruitment of opposing motors (Schuster et al., 2011). The physiological reasons for opposing motors acting on the same cargo is not entirely clear, but possible reasons for such a set-up could be to avoid ‘roadblocks’ (i.e. the co ...
as a PDF
as a PDF

... Lactic acid bacteria (LAB) are widely used in the production of fermented dairy products such as cheeses, yoghurts and creams because of their technological, nutritional and eventual health properties. The production of organic (mainly lactic and acetic) acids and the resulting acidification is esse ...
Apyrase Suppression Raises Extracellular ATP
Apyrase Suppression Raises Extracellular ATP

... (GO) category analyses, and they were assigned a functional categorization by annotation for GO Biological Processes. The significant trends in these results showed that genes related to stress responses were the ones that most changed expression when APY1 and APY2 were suppressed (Supplemental Fig. ...
Poster
Poster

... ordered crystals required for structural studies. However, a small seven amino acid sequence (GNNQQNY) from Sup35's N-terminus was crystallized by Nelson et al. (2005). We have constructed a 3D physical model of GNNQQNY as part of ...
Lysosomal and vacuolar sorting: not so different
Lysosomal and vacuolar sorting: not so different

... biochemist, discovered mammalian lysosomes entirely based on biochemical methods [2] and as he calls it himself by ‘a gift of serendipity’ while working on insulin [3]. de Duve named lysosomes respective of their digestive properties (from the Greek lysis- digestive and soma-body) and their existenc ...
View Full PDF - Biochemical Society Transactions
View Full PDF - Biochemical Society Transactions

... biochemist, discovered mammalian lysosomes entirely based on biochemical methods [2] and as he calls it himself by ‘a gift of serendipity’ while working on insulin [3]. de Duve named lysosomes respective of their digestive properties (from the Greek lysis- digestive and soma-body) and their existenc ...
Chapter 7 Membrane Structure and Function
Chapter 7 Membrane Structure and Function

... 40) A patient has had a serious accident and lost a lot of blood. In an attempt to replenish body fluids, distilled water, equal to the volume of blood lost, is transferred directly into one of his veins. What will be the most probable result of this transfusion? A) It will have no unfavorable effe ...
Infectious Hematopoietic Necrosis recombinant viruses induce
Infectious Hematopoietic Necrosis recombinant viruses induce

... immunosorbent assay (ELISA) previously described (Romero et al. 2005). For the ELISA, 96 well-plates were coated overnight with IHNV (2x106 pfu ml- ...
Fibronectin and a5b1 integrin mediate binding of Pseudomonas
Fibronectin and a5b1 integrin mediate binding of Pseudomonas

... through a variety of bacterial strategies including binding to epithelial receptors present at the surface of the respiratory epithelium. In order to characterize the adherence sites for P. aeruginosa in damaged and repairing bronchial tissue, an ex vivo model of airway epithelial injury and repair ...
Humic matter elicits proton and calcium fluxes and signaling
Humic matter elicits proton and calcium fluxes and signaling

... showed by Trevisan et al. [14] using the DR5::GUS construct in Arabidopsis, and evidence for their involvement in plasma membrane H+-ATPase activation has been recently reported [7,15]. This enzyme creates the electrochemical gradient of H+ that energizes secondary transport processes, including ion ...
Cytotoxic T Cells Sufficient to Induce Primary and Memory Soluble
Cytotoxic T Cells Sufficient to Induce Primary and Memory Soluble

... CD40 triggering induces primary expansion of CD8 T cells The adoptive transfer system allows the determination of the effect of CD40 triggering on Ag-specific clonal expansion and lytic activity on a per cell basis in vivo. Activation of OVA-specific OT-I TCR transgenic T cells with soluble OVA (sOV ...
Nucleic Acid AptamerssFrom Selection in Vitro to Applications in Vivo
Nucleic Acid AptamerssFrom Selection in Vitro to Applications in Vivo

... while variant bases are in lowercase. The three nucleotides critical for amino acid specificity (13, 29, and 31) are indicated by circles (for citrulline) and boxes (for arginine). The tertiary structure is shown for the citrulline-binding aptamer.23 (B) Secondary structure of the FMN aptamer and te ...
Association of Calmodulin and an Unconventional Myosin with the
Association of Calmodulin and an Unconventional Myosin with the

... E are exploring the roles played by calmodulin in the eukaryotic microorganism Dictyostelium discoideum. Calmodulin is a small, highly conserved, calcium-binding protein found in all eukaryotic cells; it has been implicated in the regulation of many aspects of cellular metabolism and cell motility ( ...
FEMS Microbiology Ecology 24
FEMS Microbiology Ecology 24

... The CSC of three strains, A. brasilense Cd, A. brasilense Sp-245, and A. lipoferum 1842 grown on solid and liquid NB media, was evaluated following different treatments. These treatments were to evaluate whether external treatment of the cells (as those that may occur in the soil) can change the CSC ...
That Impairs Th1-Type Immunity Down
That Impairs Th1-Type Immunity Down

... by bacillus Calmette-Guérin, the TB vaccine bacillus (30). The current literature suggests that the inflammatory response of macrophages is terminated in part by several intracellular regulators, including IL receptor-associated kinase M (IRAK-M) and SOCS (28, 31, 32). IRAK-M dampens TLR signaling, ...
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