The integrin–actin connection, an eternal love affair
... microtubular network and the directed movement of the cells (Etienne-Manneville and Hall, 2003). Finally, complexity is added by the fact that integrin-associated molecules are multifunctional. Integrin-linked actin binding proteins attach to signalling molecules and function as platforms, which bri ...
... microtubular network and the directed movement of the cells (Etienne-Manneville and Hall, 2003). Finally, complexity is added by the fact that integrin-associated molecules are multifunctional. Integrin-linked actin binding proteins attach to signalling molecules and function as platforms, which bri ...
Pseudorabies Virus: A Highly Specific
... or transmitter enzymesin virally infected neurons(Strack et al., 1989a,b; Spenceret al., 1990).Thus, this procedurecan be used to study the neuroanatomicalconnectionsof specificchemically coded central neurons. Becauseof the latter reason, our laboratory has been particularly interested in determini ...
... or transmitter enzymesin virally infected neurons(Strack et al., 1989a,b; Spenceret al., 1990).Thus, this procedurecan be used to study the neuroanatomicalconnectionsof specificchemically coded central neurons. Becauseof the latter reason, our laboratory has been particularly interested in determini ...
Article - Archive ouverte UNIGE
... dermal papillae after papilla removal, or lower follicle amputation (Oliver, 19666; Jahoda et al. 1991). The finding that cultured rat vibrissa dermal papilla cells (Jahoda and Oliver, 1981) retain their capacity to stimulate hair growth (Jahoda et al. 1984; Home et al. 1986) distinguishes them as a ...
... dermal papillae after papilla removal, or lower follicle amputation (Oliver, 19666; Jahoda et al. 1991). The finding that cultured rat vibrissa dermal papilla cells (Jahoda and Oliver, 1981) retain their capacity to stimulate hair growth (Jahoda et al. 1984; Home et al. 1986) distinguishes them as a ...
8 DJ Begley Short Res CV 4-2013-1
... (BBB) and the blood-cerebrospinal fluid barrier (BCSFB). In particular: Structure-activity relationships (SAR) of brain uptake. The physico-chemical factors determining the uptake, transport and interactions of drugs, peptides, hormones and other solutes at the blood-brain interfaces. CNS, drug targ ...
... (BBB) and the blood-cerebrospinal fluid barrier (BCSFB). In particular: Structure-activity relationships (SAR) of brain uptake. The physico-chemical factors determining the uptake, transport and interactions of drugs, peptides, hormones and other solutes at the blood-brain interfaces. CNS, drug targ ...
Early Development of the Japanese Spiny Oyster (Saccostrea
... embryogenesis, we sequenced the 5’ ends of 106 clones selected randomly from a gastrula-stage cDNA library (Oda et al., 2002). Among the 106 clones, 46 independent transcripts (from 49 clones read) showed significant similarity to known sequences in the Uniprot database (the cut-off value was less t ...
... embryogenesis, we sequenced the 5’ ends of 106 clones selected randomly from a gastrula-stage cDNA library (Oda et al., 2002). Among the 106 clones, 46 independent transcripts (from 49 clones read) showed significant similarity to known sequences in the Uniprot database (the cut-off value was less t ...
ER Membrane Protein Complex Required for Nuclear
... movement and subsequent alignment of nuclei that precedes their fusion. These include mutations that cause defects in microtubule stability and/or morphology, such as those that affect the TUB2 (encoding [3-tubulin), KAR4, and KAR9 genes (17, 18), and mutations that affect microtubule-based movement ...
... movement and subsequent alignment of nuclei that precedes their fusion. These include mutations that cause defects in microtubule stability and/or morphology, such as those that affect the TUB2 (encoding [3-tubulin), KAR4, and KAR9 genes (17, 18), and mutations that affect microtubule-based movement ...
The Role of Model Organisms in the History of Mitosis
... events, such as cases of unequal segregation or transposition. In addition, she rightly pointed out that differentiated cells often arise after asymmetric mitosis. She stated that different gene regulations arise from daughter cells formed by asymmetric cell divisions in which one daughter cell gain ...
... events, such as cases of unequal segregation or transposition. In addition, she rightly pointed out that differentiated cells often arise after asymmetric mitosis. She stated that different gene regulations arise from daughter cells formed by asymmetric cell divisions in which one daughter cell gain ...
Mechanisms linking obesity to insulin resistance and type 2 diabetes
... to intravenous glucose, despite the fact that β–cells in type 2 diabetes clearly contain insulin. Second: delivery of non-glucose secretagogues can acutely increase insulin release but dose not result in equivalent responses to those seen with similar stimulation in healthy subjects. Third: although ...
... to intravenous glucose, despite the fact that β–cells in type 2 diabetes clearly contain insulin. Second: delivery of non-glucose secretagogues can acutely increase insulin release but dose not result in equivalent responses to those seen with similar stimulation in healthy subjects. Third: although ...
Human CHMP6, a myristoylated ESCRT-III protein, interacts directly
... a mammalian orthologue of yeast Class E Vps31/Bro1) interacts with viral Gag proteins and serves as a bridge between the selected components of ESCRT-I and ESCRT-III, i.e. Tsg101 and a mammalian orthologue of yeast Snf7 named CHMP (charged MVB protein) 4 respectively. From the viewpoint of membrane ...
... a mammalian orthologue of yeast Class E Vps31/Bro1) interacts with viral Gag proteins and serves as a bridge between the selected components of ESCRT-I and ESCRT-III, i.e. Tsg101 and a mammalian orthologue of yeast Snf7 named CHMP (charged MVB protein) 4 respectively. From the viewpoint of membrane ...
S-layer Structure in Bacteria and Archaea
... with layered supramolecular architectures surrounding the cytoplasmic membrane. Of the finest examples of such supramolecular cell wall components are surface or S-layers. These regular paracrystalline pericellular structures were first observed in the bacterium Spirillum serpens and in the archaeum ...
... with layered supramolecular architectures surrounding the cytoplasmic membrane. Of the finest examples of such supramolecular cell wall components are surface or S-layers. These regular paracrystalline pericellular structures were first observed in the bacterium Spirillum serpens and in the archaeum ...
Reviews
... of this paper is the following: The first section, after some preliminary classification and definition, will deal with some of the most important biological properties of HA, introducing its interactions with proteins, cells, and tissue. Then, since the molecular structure of HA is at the basis of ...
... of this paper is the following: The first section, after some preliminary classification and definition, will deal with some of the most important biological properties of HA, introducing its interactions with proteins, cells, and tissue. Then, since the molecular structure of HA is at the basis of ...
Transmembrane domains control exclusion of membrane proteins
... are concentrated in transport vesicles are depleted from the donor compartment and enriched in the acceptor compartment. Proteins that are excluded from transport vesicles are restricted to the donor compartment. Both mechanisms are not mutually exclusive and might act in concert to ensure efficient ...
... are concentrated in transport vesicles are depleted from the donor compartment and enriched in the acceptor compartment. Proteins that are excluded from transport vesicles are restricted to the donor compartment. Both mechanisms are not mutually exclusive and might act in concert to ensure efficient ...
Drosophila C-terminal Binding Protein Functions as a Context
... Transcriptional repression plays a major role in segmentation gene expression that leads to proper body patterning during early Drosophila development (cf. Refs. 1 and 4). A number of different transcriptional repressors present in the early Drosophila embryo have been shown to encode sequence-speci ...
... Transcriptional repression plays a major role in segmentation gene expression that leads to proper body patterning during early Drosophila development (cf. Refs. 1 and 4). A number of different transcriptional repressors present in the early Drosophila embryo have been shown to encode sequence-speci ...
GARDNER, CARTON & DOUGLAS
... product sample collection, contains batch requirements that are inappropriate for a product quality BE assessment. Because of the critical nature of this testing in the BE assessment, and because of the limited number (three) of batches examined, it is appropriate and fair to require three productio ...
... product sample collection, contains batch requirements that are inappropriate for a product quality BE assessment. Because of the critical nature of this testing in the BE assessment, and because of the limited number (three) of batches examined, it is appropriate and fair to require three productio ...
Specialized filopodia direct long-range transport of SHH
... cellular level remains poorly understood1. For more than a century, the vertebrate limb bud has served as a model for studying cell signalling during embryonic development2. Here we optimize single-cell realtime imaging to delineate the cellular mechanisms for how signalling proteins, such as sonic ...
... cellular level remains poorly understood1. For more than a century, the vertebrate limb bud has served as a model for studying cell signalling during embryonic development2. Here we optimize single-cell realtime imaging to delineate the cellular mechanisms for how signalling proteins, such as sonic ...
COMPOUND-INDUCED HOST CELL RESPONSES AND EFFECTS ON WHOLE VIRUS CHAPTER 4
... clinical trials (Hamid et al., 2004) with toxicity and adverse effects being some of the reasons for the failures. While the in silico prediction models (covered in chapter 3) provides insights into potential toxicity and can significantly shorten the drug discovery time line (Lobell and Sivarajah, ...
... clinical trials (Hamid et al., 2004) with toxicity and adverse effects being some of the reasons for the failures. While the in silico prediction models (covered in chapter 3) provides insights into potential toxicity and can significantly shorten the drug discovery time line (Lobell and Sivarajah, ...
Co-option of an endogenous retrovirus envelope for host defense in
... containing antibiotic resistance or fluorescent protein genes (Figure 2A). This procedure progressively enriched MLV-ancHTenv-susceptible DF-1 cells (Figure 2—figure supplement 1A). Lentiviralvector directed PCR primers were then used to identify a human cDNA in the selected cells, that encoded huma ...
... containing antibiotic resistance or fluorescent protein genes (Figure 2A). This procedure progressively enriched MLV-ancHTenv-susceptible DF-1 cells (Figure 2—figure supplement 1A). Lentiviralvector directed PCR primers were then used to identify a human cDNA in the selected cells, that encoded huma ...
Respiratory System - eCurriculum
... Regenerate type I and type II cells Mitochondria, RER, Golgi Vacuoles containing the phospholipid surfactant Surfactant lowers surface tension of alveoli ...
... Regenerate type I and type II cells Mitochondria, RER, Golgi Vacuoles containing the phospholipid surfactant Surfactant lowers surface tension of alveoli ...
Disruption of a Dynamin Homologue Affects Endocytosis, Organelle
... Measurement of Pinocytosis and Phagocytosis Fluid-phase endocytosis and exocytosis of surface-attached wildtype Ax2, rescue cells, and dymA2 cells were quantitatively analyzed using a method adapted from Bacon et al. (1994). Cells were grown to confluency on 6-cm Petri dishes or in shaking culture a ...
... Measurement of Pinocytosis and Phagocytosis Fluid-phase endocytosis and exocytosis of surface-attached wildtype Ax2, rescue cells, and dymA2 cells were quantitatively analyzed using a method adapted from Bacon et al. (1994). Cells were grown to confluency on 6-cm Petri dishes or in shaking culture a ...
1. (a) cells if more than one box is ticked, award no mark 1 (b) tail 1
... blood flowing around the body’ ‘you would die’ is insufficient ...
... blood flowing around the body’ ‘you would die’ is insufficient ...
Photosynthesis and Cellular Respiration: Original
... 7. The light-dependent reactions produce oxygen gas and convert ADP and NADP+ into ATP and NADPH. The light-dependent reactions occur in different ares of the thylakoid, called photosystem I and photosystem II. 8. The Calvin uses ATP and NADPH from the light-dependent reactions to produce high-energ ...
... 7. The light-dependent reactions produce oxygen gas and convert ADP and NADP+ into ATP and NADPH. The light-dependent reactions occur in different ares of the thylakoid, called photosystem I and photosystem II. 8. The Calvin uses ATP and NADPH from the light-dependent reactions to produce high-energ ...
A Novel Plant Kinesin-Related Protein Specifically
... (RACE) experiments were performed. We predicted that the full-length open reading frame would encode a polypeptide of 869 amino acids, which has been named AtPAKRP2 (Figure1). The deduced polypeptide has a calculated molecular mass of 97 kD and a pI of 5.8. The deduced AtPAKRP2 sequence showed a num ...
... (RACE) experiments were performed. We predicted that the full-length open reading frame would encode a polypeptide of 869 amino acids, which has been named AtPAKRP2 (Figure1). The deduced polypeptide has a calculated molecular mass of 97 kD and a pI of 5.8. The deduced AtPAKRP2 sequence showed a num ...