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University of Groningen Effects of structure, morphology and
University of Groningen Effects of structure, morphology and

... The striped bars represent total fibrinogen measurements after 180 minutes of incubation with fibrinogen solution (n = 3). The amount of fibrinogen P2 epitope exposure on uncoated PET (BARE), poly(ethylene imine) coated PET (PEI), heparincoated PET (HEP) and poly(tetrafluoro ethylene) (PTFE) (n = 3) ...
Get PDF file - Botanik in Bonn
Get PDF file - Botanik in Bonn

... established features of the periphery of higher plant cells. Together with transmembrane synthase complexes, they represent the most characteristic form of a “cell periphery complex” of higher plant cells which determines the orientation of the diffuse (intercalary) type of their cell growth. Howeve ...
- ATS Journals
- ATS Journals

... presence of the mutation. The entire WT and G773D cDNAs were sequenced to ensure that no other significant mutations had been introduced during cloning. Large scale preparation of plasmid DNA was achieved by growing transformed cells in Circlegro media containing Ampicillin, followed by plasmid puri ...
Cell cycle progression in response to oxygen levels | SpringerLink
Cell cycle progression in response to oxygen levels | SpringerLink

... debate within the hypoxia field. Several groups have shown that the induction of the cell cycle inhibitors p21 and p27 is dependent on HIF1α [62, 66]. Work using mouse embryonic fibroblasts and splenic B lymphocytes demonstrated that cell cycle arrest during hypoxia was HIF1α dependent but p53 indep ...
A comparison between nuclear dismantling during plant and animal
A comparison between nuclear dismantling during plant and animal

... Therefore, the nucleus of apoptotic animal cells becomes degraded inside another cell. In contrast, in plant cells undergoing PCD, the nucleus is not degraded in another cell, which is a clear difference of nuclear dismantling between plant and animal cell death. Despite these differences, nuclear e ...
Early Cell Cycle Entry and Cell Division Murine Neonatal
Early Cell Cycle Entry and Cell Division Murine Neonatal

... RAG2⫺/⫺ hosts (Fig. 2, right column). Together, these results indicate that faster kinetics of proliferation is a universal phenomenon among neonatal T cell populations—it occurs both in vivo and in vitro, it occurs in several strains of mice, and it occurs whether stimulation is through the CD3/TCR ...


... taking in materials that the body needs but also excreting waste products that result from metabolism—the chemical activity that takes place inside living cells. One-celled organisms absorb nutrients directly from their environment. This is also true of simple animals, such as sponges and coelentera ...
Chapter 6 The Lymphatic and Immune Systems
Chapter 6 The Lymphatic and Immune Systems

... section of the small intestine) generate lymphocytes to help protect from infection due to pathogens Vermiform appendix – hangs from the lower portion of the cecum (1st section of the large intestine). Thought to be a vestigial organ and while once believed to be useless, recent research indicates i ...
Protist Characteristics
Protist Characteristics

... • spore: A reproductive cell produced by various organisms; can withstand harsh environmental conditions. • symbiosis: Close relationship between organisms of different species in which at least one of the organisms benefits from the relationship. • vacuole: Large saclike organelle that stores and t ...
Role of the p53 Tumor Suppressor Gene in Cell Cycle Arrest and
Role of the p53 Tumor Suppressor Gene in Cell Cycle Arrest and

... Results and Discussion In the present study we assessed the role of Ihe p53 tumor suppres sor gene in cell cycle arrest and radiosensitivity of 17 Burkitt's lymphoma and lymphoblastoid cell lines. The purpose of these studies was to determine whether the presence of a normal p53 gene was essential f ...
Cell Biology - Educational Services
Cell Biology - Educational Services

... • cell: Basic unit of structure and function of a living organism; the basic unit of life. • cell theory: Scientific theory that all living things are made up of cells, all life functions occur within cells, and all cells come from already existing cells. • electron microscope: Microscope that uses ...
Plant and animal cells
Plant and animal cells

... Structure of cellulose • Like starch, cellulose is composed of a long chain of at least 500 glucose molecules. Cellulose is thus a polysaccharide. Several of these polysaccharide chains are arranged in parallel arrays to form cellulose microfibrils. • The individual polysaccharide chains are bound ...
Module 4 - Australian College of Sport and Fitness
Module 4 - Australian College of Sport and Fitness

... resistance. In the fitness world, this typically refers to things like how much weight you can lift or  how many push ups you can do. This type of resistance can include dumbbells, barbells, resistance  bands,  machines,  cables  or  your  own  body.  When  lifting  heavy  weight,  you  increase  st ...
functional differentiation of enterocytes in the follicle
functional differentiation of enterocytes in the follicle

... autoradiograph of sectioned tissue taken in the region of a Peyer's patch is shown in Fig. 1 A. Radioactivity is seen to be concentrated in the dome region of the FAE and in the upper half of surrounding villi. These villi appear to take up significantly greater amounts of valine than does the FAE. ...
localization of products of atp hydrolysis in mammalian smooth
localization of products of atp hydrolysis in mammalian smooth

... technique to more closely approximate optimal conditions for enzyme activity. Since, in this laboratory, attempts at isolation of the agranular endoplasmic reticulum of smooth muscle and characterization of an ATPase at this site were not successful, the adjustments in pH of the medium and the catio ...
Tissue Lab Practical Review
Tissue Lab Practical Review

... Tissue Lab Practical Review For Mrs. Nemanic’s Stellar Students! ...
Biotech applications – hybridomas and monoclonal antibodies
Biotech applications – hybridomas and monoclonal antibodies

... B-cell and thus behave as a vaccine against mycobacterium tuberculosis. It has a strong inflammatory effect on some tissues, and has thus been also approved as a treatment for bladder cancer. The bad side is that PAMPs can induce massive cytokine production, which can result in fever and shock. This ...
Botanical Gazette
Botanical Gazette

... Sporophyll idioblasts appear to be related to interactions with insect predators and/or cosymbionts and may form part of a complex pollination syndrome. The lack of idioblasts in stem tissue and low concentration in leaflet tissue of Zamiafutfiuracea compared with sporophyll tissue is significant su ...
Yeast longevity and aging—the mitochondrial connection
Yeast longevity and aging—the mitochondrial connection

... communication (Butow, 2002). This signaling pathway is triggered by mitochondrial dysfunction. It is most readily observed in petite yeast cells. These are cells that have dysfunctional mitochondria, because of mutations in or complete lack of mitochondrial DNA (Parikh et al., 1987) or because of mu ...
The plant endoplasmic reticulum: a cell-wide web
The plant endoplasmic reticulum: a cell-wide web

... as Golgi bodies, peroxisomes and, to some extent, mitochondria. The movement characteristics of the ER network are more complicated, and algorithms to relatively easily monitor ER characteristics such as tubule growth, network remodelling and surface area compared with volume are currently underway ...
The importance of the five phosphoribosyl
The importance of the five phosphoribosyl

... growth were fixed in formaldehyde\methanol exactly as described by Wente et al. (1992). Antisera AK39 (peptide 1) and AK41 (peptide 2), described by Carter et al. (1997), were pre-adsorbed onto fixed cells and subsequently used at a 1 : 2700 (AK39) and a 1 : 900 (AK41) dilution. Binding of AK39 or A ...
Homeostasis / Allostasis
Homeostasis / Allostasis

... Constantly present ...
Intracellular catalysis of disulfide bond formation by the human
Intracellular catalysis of disulfide bond formation by the human

... Many secreted proteins contain disulfide bonds, which are required for their proper folding, function and stability. In eukaryotic cells disulfide bond formation usually occurs while the protein folds in the lumen of the ER (endoplasmic reticulum). While disulfide bonds can be formed spontaneously i ...
BET bromodomain inhibition suppresses TH17
BET bromodomain inhibition suppresses TH17

... of BET in controlling multiple effector TH17-enriched cytokines, JQ1 also abrogated IL-21 and GM-CSF production (Fig. 2 G). In contrast, the ability of these cells to produce TNF protein was only modestly ameliorated (Fig. 2 H, left) and not reduced at the transcript level (Fig. 2 H, middle). Moreov ...
Cell Wall Loosening by Expansins
Cell Wall Loosening by Expansins

... When cDNAs for the two cucumber hypocotyls expansins were cloned and sequenced, we found that they encoded very similar and novel proteins (Shcherban et al., 1995). For each cucumber expansin, the primary translation product is predicted to be approximately 27 kD and includes a signal peptide of 22 ...
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Organ-on-a-chip

An organ-on-a-chip (OC) is a multi-channel 3-D microfluidic cell culture chip that simulates the activities, mechanics and physiological response of entire organs and organ systems. It constitutes the subject matter of significant biomedical engineering research, more precisely in bio-MEMS. The convergence of labs-on-chips (LOCs) and cell biology has permitted the study of human physiology in an organ-specific context, introducing a novel model of in vitro multicellular human organisms. One day, they will perhaps abolish the need for animals in drug development and toxin testing.Although multiple publications claim to have translated organ functions onto this interface, the movement towards this microfluidic application is still in its infancy. Organs-on-chips will vary in design and approach between different researchers. As such, validation and optimization of these systems will likely be a long process. Organs that have been simulated by microfluidic devices include the heart, the lung, kidney, artery, bone, cartilage, skin and more.Nevertheless, building valid artificial organs requires not only a precise cellular manipulation, but a detailed understanding of the human body’s fundamental intricate response to any event. A common concern with organs-on-chips lies in the isolation of organs during testing. ""If you don’t use as close to the total physiological system that you can, you’re likely to run into troubles"" says William Haseltine, founder of Rockville, Maryland. Microfabrication, microelectronics and microfluidics offer the prospect of modeling sophisticated in vitro physiological responses under accurately simulated conditions.
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