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NOTES
NOTES

... (*What is diffusion? What is ultrafiltration? P.767-768-know these definitions) b. Dialysis: diffusion of solute molecules across semipermealble membrane from high to low solute concentration 1) Used to remove excess fluid and metabolic wastes produced in renal failure 2) Dialysate: dialysis soluti ...
Mutations in Actin-Related Proteins 2 and 3 Affect Cell Shape
Mutations in Actin-Related Proteins 2 and 3 Affect Cell Shape

... Based on the mutations, the protein truncations in wrm1-2, dis1-1, and dis1-2 would be predicted to occur after amino acids 14, 97, and 290, respectively (Figure 1C). The G-to-A change in wrm1-1 results in the alteration of a conserved Gly (position 151; Figure 1C) to Asp and may lead to a pivotal c ...
The functional cobalamin (vitamin B12)–intrinsic factor receptor is a
The functional cobalamin (vitamin B12)–intrinsic factor receptor is a

... site (CUB domains 5-8).5,6 Although cubilin has no apparent transmembrane segment or cytoplasmic tail, several studies have shown that binding of IF-cobalamin to cubilin leads to endocytosis of the ligand and recycling of the receptor.2,3 Besides expression and function in the intestine, cubilin has ...
The importance of Src homology 2 domain-containing
The importance of Src homology 2 domain-containing

... codon (*) is at exon 1. The SAM domain spans from exons 1 to 4. Part of exon 1, along with exons 2 and 3, is replaced by PGK-Neo, which is later deleted upon crossing with ␤-actin Cre transgenic mice. Œ, Represent the Loxp sites. P1 and P2 represent PCR primers used for ES clone screening. P⬘ repres ...
Match the following terms related to edema.
Match the following terms related to edema.

... This inflammatory exudate in the tissues results in the swelling associated with inflammation. The protein-rich exudate of inflammation must be differentiated from a transudate, a low-protein fluid, such as that seen in the pulmonary edema that develops in congestive heart failure. REF: p. 3 19. The ...
Test Bank - rsffa.org
Test Bank - rsffa.org

... 8. Which structures in the cells shown in Figure 7–9 above are responsible for meeting the cells’ energy needs? Based on the presence or absence of these structures, identify which cell is a plant cell. 9. What advantages do cell walls provide plant cells that contact fresh water? 10. What would hap ...
Control of Mitotic Events by Nap1 and the Gin4 Kinase
Control of Mitotic Events by Nap1 and the Gin4 Kinase

... the cyclins somehow function to provide cyclin-dependent kinase complexes with specificity. To learn more about how cyclins might function in this capacity, we used affinity chromatography to identify proteins that interact with one kind of cyclin, but not with others. We reasoned that such proteins ...
Hexose transport and phosphorylation by capillaries - AJP-Cell
Hexose transport and phosphorylation by capillaries - AJP-Cell

... case transport in several other cell systems including Even at 25”C, 3MG uptake was nearly half-equilithe BBB (15). In isolated brain capillaries it clearly brated by 10 s. Because this was the earliest time point inhibited 3MG transport and reduced the initial uptake that could be reliably measured ...
A differential requirement for SUMOylation in proliferating and non
A differential requirement for SUMOylation in proliferating and non

... more pleiotropic effects following a global block of SUMO conjugation, we further demonstrate that low levels of global substrate SUMOylation are detected in mutants lacking either or both E1 subunits. These results not only suggest that minimal SUMOylation persists in the absence of Aos1/Uba2, but ...
Maintaining a Balance - The Bored of Studies Community
Maintaining a Balance - The Bored of Studies Community

... Reason ...
Formation of submicron colloidal particles from marine bacteria by
Formation of submicron colloidal particles from marine bacteria by

... these part1clc.s Into the glass wall of the flask is also possible, because glass I S k n o ~ v nto adsorb biopolymels such a s ploteins Third, aggregation of particles larger than 4 03 pm might occur Hydrophobic interactlon of bacterlal membrane components (for example, proteins and Iipids) IS prob ...
Cnidarians: An evolutionarily conserved model system for
Cnidarians: An evolutionarily conserved model system for

... in bilaterian embryogenesis act during cnidarian regeneration. Therefore, the intriguing possibility exists that a common set of genes might control at least the early steps of the regeneration process in cnidarians and bilaterians. We presume that the high or even unlimited regenerative capacity ch ...
Understanding Peripheral Artery Disease
Understanding Peripheral Artery Disease

... You may also call Boston Scientific customer service at 1.888.272.1001 for more information. Magnetic Resonance Conditional A patient with this device can be scanned safely only under specific conditions. Failure to follow the conditions may result in severe injury. Non-clinical testing has demonstr ...
Document
Document

... bottom is not necessary when using semi global alignment (zero endgaps). Rest works as under global alignment. ...
Simulations Suggest Information Processing Roles for the Diverse
Simulations Suggest Information Processing Roles for the Diverse

Supplement
Supplement

... problem, its history, importance and applications. See for example [1,2]. Maximal independent set (MIS) is a symmetry breaking problem extensively used in practice. For networks in which not all processes are directly connected to each other, MIS seeks to elect several local leaders which, together, ...
Skeletal muscle cells
Skeletal muscle cells

... Muscle Regeneration and Growth Skeletal Muscle • Increase in size (hypertrophy) • Increase in number (regeneration/proliferation) • Satellite cells are proposed source of regenerative cells Smooth Muscle • Increase in size (hypertrophy) • Increase in number (regeneration/proliferation) • Smooth mus ...
Antisickling Activity and Membrane Stabilizing Effect of
Antisickling Activity and Membrane Stabilizing Effect of

... mutant hemoglobin polymerizes inside the red blood cell into a gel or further into fibers leading to a drastic decrease in the red cell deformability. Polymerization and precipitation of S hemoglobin within the erythrocytes cause the change of the shape of erythrocytes from their normal globular for ...
The Australian Stem Cell Handbook  What you should know about stem cell
The Australian Stem Cell Handbook What you should know about stem cell

... can be maintained as self-renewing stem cells indefinitely in the laboratory (unlike most tissue-specific stem cells) and potentially can differentiate or turn into any cell type in the human body. Human ESCs are derived from donated human embryos at a very early stage of development (approximately ...
Superior Sagittal Sinus Thrombosis With Infarction in Sickle Cell Trait
Superior Sagittal Sinus Thrombosis With Infarction in Sickle Cell Trait

... was the proposed etiology in both cases of Schenk1 and Dalai et al. 2 In our case, there was no known precipitating event or other risk factor. When erythrocytes containing hemoglobin S are exposed to low oxygen tension, tactoids or polymerized fibers of abnormal hemoglobin are formed, resulting in ...
Possible new intranuclear symbionts of Paramecium caudatum
Possible new intranuclear symbionts of Paramecium caudatum

... were shown to have many common features. Symbionts from both locations are rod-shaped gram-negative bacteria with similar size; they occupy the Ma and often form dense aggregations; inside the aggregation chromatin bodies are less dense and nucleoli are absent, while outside the group of symbionts t ...
view - Scan. Vet. Press
view - Scan. Vet. Press

Chapter 36 PowerPoint
Chapter 36 PowerPoint

... (a) Initial conditions: cellular ψ > environmental ψ ...
Focused Renal and Urinary Assessment
Focused Renal and Urinary Assessment

... Bowman’s capsule - Part of the renal corpuscle. It consists of a visceral layer of podocytes closely applied to the glomerulus and an outer parietal layer. The podocyte layer is part of the filter for the formation of renal filtrate in the space between the two layers. ...
Two-step process for photoreceptor formation inDrosophila
Two-step process for photoreceptor formation inDrosophila

... Here, we demonstrate that photoreceptor development is a twostep process and that each step is under different genetic regulation. In the ®rst step, the cells adopt their fate as neurons, become committed, and send speci®c axonal projections. During this recruitment stage, the PRCs are predetermined ...
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Organ-on-a-chip

An organ-on-a-chip (OC) is a multi-channel 3-D microfluidic cell culture chip that simulates the activities, mechanics and physiological response of entire organs and organ systems. It constitutes the subject matter of significant biomedical engineering research, more precisely in bio-MEMS. The convergence of labs-on-chips (LOCs) and cell biology has permitted the study of human physiology in an organ-specific context, introducing a novel model of in vitro multicellular human organisms. One day, they will perhaps abolish the need for animals in drug development and toxin testing.Although multiple publications claim to have translated organ functions onto this interface, the movement towards this microfluidic application is still in its infancy. Organs-on-chips will vary in design and approach between different researchers. As such, validation and optimization of these systems will likely be a long process. Organs that have been simulated by microfluidic devices include the heart, the lung, kidney, artery, bone, cartilage, skin and more.Nevertheless, building valid artificial organs requires not only a precise cellular manipulation, but a detailed understanding of the human body’s fundamental intricate response to any event. A common concern with organs-on-chips lies in the isolation of organs during testing. ""If you don’t use as close to the total physiological system that you can, you’re likely to run into troubles"" says William Haseltine, founder of Rockville, Maryland. Microfabrication, microelectronics and microfluidics offer the prospect of modeling sophisticated in vitro physiological responses under accurately simulated conditions.
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