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The plant endoplasmic reticulum: a cell-wide web
The plant endoplasmic reticulum: a cell-wide web

... as Golgi bodies, peroxisomes and, to some extent, mitochondria. The movement characteristics of the ER network are more complicated, and algorithms to relatively easily monitor ER characteristics such as tubule growth, network remodelling and surface area compared with volume are currently underway ...
Tissue Lab Practical Review
Tissue Lab Practical Review

... Tissue Lab Practical Review For Mrs. Nemanic’s Stellar Students! ...
Intracellular catalysis of disulfide bond formation by the human
Intracellular catalysis of disulfide bond formation by the human

... Many secreted proteins contain disulfide bonds, which are required for their proper folding, function and stability. In eukaryotic cells disulfide bond formation usually occurs while the protein folds in the lumen of the ER (endoplasmic reticulum). While disulfide bonds can be formed spontaneously i ...
Phosphorylation of Bni4 by MAP kinases contributes to septum
Phosphorylation of Bni4 by MAP kinases contributes to septum

... the chitin ring was shown to play a homeostatic role in the maintenance of cell integrity at the time of cytokinesis (Cabib and Schmidt 2003; Gomez et al. 2009), which would explain the complex pattern of synthetic lethality (SL) associated with the absence of CSIII activity. In addition, CSIII is a ...
Document
Document

... The lungs have two jobs: 1 to collect oxygen from the air 2 to deliver carbon dioxide to the air This means that they need 1 a large surface area for this swapping of gases to take place 2 ways to prevent the surfaces being clogged up with dust from the air 3 a good blood supply and circulatory syst ...
Role of active oxygen species and NO in plant defence
Role of active oxygen species and NO in plant defence

... apoplastic peroxidases require Ca2+ for optimal activity. The gp91phox has also been considered a target for kinase action linked to Ca2+ fluxes [3•]. It has been postulated that the mammalian NADPH oxidase is activated by a protein kinase C PKC mediated phosphorylation of p47 and p67. A functional ...
Chapter 24 Introduction to Animals
Chapter 24 Introduction to Animals

... In order to understand the next branching point on the evolutionary tree, it is important to know about certain features of animals with bilateral symmetry. Body plans of animals with bilateral symmetry include the gut, which is either a sac inside the body or a tube that runs through the body, wher ...
localization of products of atp hydrolysis in
localization of products of atp hydrolysis in

... technique to more closely approximate optimal conditions for enzyme activity. Since, in this laboratory, attempts at isolation of the agranular endoplasmic reticulum of smooth muscle and characterization of an ATPase at this site were not successful, the adjustments in pH of the medium and the catio ...
Cytotoxic T Cells Sufficient to Induce Primary and Memory Soluble
Cytotoxic T Cells Sufficient to Induce Primary and Memory Soluble

... CD40 triggering induces primary expansion of CD8 T cells The adoptive transfer system allows the determination of the effect of CD40 triggering on Ag-specific clonal expansion and lytic activity on a per cell basis in vivo. Activation of OVA-specific OT-I TCR transgenic T cells with soluble OVA (sOV ...
CiC3-1a-Mediated Chemotaxis in the Deuterostome Invertebrate
CiC3-1a-Mediated Chemotaxis in the Deuterostome Invertebrate

... receptor molecule mediating the chemotactic effect is Gi protein coupled. Immunohistochemical analysis with anti-rCiC3-1aspecific Ab and in situ hybridization experiments with a riboprobe corresponding to the 3ⴕ-terminal sequence of CiC3-1, performed on tunic sections of LPS-injected animals, showed ...
THE RENAL ELECTROGENIC Na+:HCO3 COTRANSPORTER
THE RENAL ELECTROGENIC Na+:HCO3 COTRANSPORTER

... channels, that could influence Vm. Thus, a DIDS-induced Vm change can hardly be regarded as specific for an electrogenic Na+:HCO3− cotransporter. Another approach that has been used to identify electrogenic Na+:HCO3− cotransporters is to monitor the Vm changes that occur when a CO2/HCO3− solution is ...
Worms and Mollusks
Worms and Mollusks

... – Live in moist, tropical countries – External parasites that suck the blood and body fluids of their host – Have powerful suckers at both ends of their bodies – Leeches are sometimes used after surgery • Can reduce swelling when a body part is reattached • Also secrete a fluid that prevents blood f ...
LEUKEMIA
LEUKEMIA

... LR is usually seen in severe infections, pregnancy, inflammation, ...
Plant PCD In vegetative development Suspensor degradation
Plant PCD In vegetative development Suspensor degradation

... Heterozygous alleles restore male fertility to cytoplasmic male-sterile radish (Raphanus sativus L.): a case of overdominance(2013) J. Exp. Bot. 64: 2041-2048. ...
Compound 48/80 Activates Mast Cell Phospholipase D
Compound 48/80 Activates Mast Cell Phospholipase D

... whole-cell lysates and the soluble and membrane fractions, as well as the separation and detection of Gai-3 protein by SDS-polyacrylamide gel electrophoresis and Western blotting, were performed as described previously (Hirasawa et al., 1995). Gels were loaded with equivalent amounts of protein. Gai ...
Document
Document

... Many cell lines used in drug discovery screening prefer to use glycolysis rather than oxidative phosphorylation to produce ATP when grown in glucose, a phenomenon known as Crabtree effect7. This can be potentially problematic when looking for adverse effects of a compound on energy metabolism, parti ...
Nitrogen deficiency inhibits leaf blade growth in Lolium
Nitrogen deficiency inhibits leaf blade growth in Lolium

... nitrate supply, and performing a kinematic analysis to assess the effect of nitrogen status on cell proliferation and cell growth in the leaf blade epidermis. Low nitrogen supply reduced leaf elongation rate (LER) by 43% through a similar decrease in the cell production rate and final cell length. T ...
Gibberellins accumulate in the elongating endodermal cells of
Gibberellins accumulate in the elongating endodermal cells of

... germination, root and shoot elongation, flowering and fruit patterning (7–9). Over the years, more than 130 GAs have been identified, of which only a few, such as GA1, GA3, and GA4, are bioactive (8). Much progress has been made in understanding how plants control GA response through regulation of bio ...
UNIT 1 – FORCE AND MOTION (SEPUP Force and
UNIT 1 – FORCE AND MOTION (SEPUP Force and

... basic units of structure and function in living things; and all presently existing cells arose from previously existing cells). B-2.2 Summarize the structures and functions of organelles found in a eukaryotic cell (including the nucleus, mitochondria, chloroplasts, lysosomes, vacuoles, ribosomes, en ...
REVIEW ARTICLE Mechanisms of pattern formation in development
REVIEW ARTICLE Mechanisms of pattern formation in development

... 2028 I. Salazar-Ciudad, J. Jernvall and S. A. Newman developing planar and solid tissues, respectively. Second, mechanisms that use cell behaviors other than signaling (we will refer to these as morphogenetic mechanisms) act on the previously established pattern to cause the formation of threedimen ...
CDHO Advisory Sickle Cell Disease
CDHO Advisory Sickle Cell Disease

... infections that may lead to further complications of sickle cell disease. 2. Dental caries and other problems are associated with sickle cell disease. 3. Dental procedures that require local anesthesia can be performed in the dental office as with any other patient/client. 4. Patients/clients with a ...
Chapter 7 Body Systems
Chapter 7 Body Systems

... • Cytoplasm—thick gel-like substance inside of the cell composed of numerous organelles suspended in watery cytosol; each type of organelle (“little organ”) is suited to perform particular functions (Figure 3-2) ...
Mutations in Actin-Related Proteins 2 and 3 Affect Cell Shape
Mutations in Actin-Related Proteins 2 and 3 Affect Cell Shape

... Based on the mutations, the protein truncations in wrm1-2, dis1-1, and dis1-2 would be predicted to occur after amino acids 14, 97, and 290, respectively (Figure 1C). The G-to-A change in wrm1-1 results in the alteration of a conserved Gly (position 151; Figure 1C) to Asp and may lead to a pivotal c ...
URINE ANALYSIS
URINE ANALYSIS

... Transitional epi’s = smaller & rounder, large nuclei. Presence of renal tubule cells = significant renal pathology. Picture: Convoluted renal tubule cells (200x) ...
NOTES
NOTES

... (*What is diffusion? What is ultrafiltration? P.767-768-know these definitions) b. Dialysis: diffusion of solute molecules across semipermealble membrane from high to low solute concentration 1) Used to remove excess fluid and metabolic wastes produced in renal failure 2) Dialysate: dialysis soluti ...
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Organ-on-a-chip

An organ-on-a-chip (OC) is a multi-channel 3-D microfluidic cell culture chip that simulates the activities, mechanics and physiological response of entire organs and organ systems. It constitutes the subject matter of significant biomedical engineering research, more precisely in bio-MEMS. The convergence of labs-on-chips (LOCs) and cell biology has permitted the study of human physiology in an organ-specific context, introducing a novel model of in vitro multicellular human organisms. One day, they will perhaps abolish the need for animals in drug development and toxin testing.Although multiple publications claim to have translated organ functions onto this interface, the movement towards this microfluidic application is still in its infancy. Organs-on-chips will vary in design and approach between different researchers. As such, validation and optimization of these systems will likely be a long process. Organs that have been simulated by microfluidic devices include the heart, the lung, kidney, artery, bone, cartilage, skin and more.Nevertheless, building valid artificial organs requires not only a precise cellular manipulation, but a detailed understanding of the human body’s fundamental intricate response to any event. A common concern with organs-on-chips lies in the isolation of organs during testing. ""If you don’t use as close to the total physiological system that you can, you’re likely to run into troubles"" says William Haseltine, founder of Rockville, Maryland. Microfabrication, microelectronics and microfluidics offer the prospect of modeling sophisticated in vitro physiological responses under accurately simulated conditions.
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