Repetitive and Prolonged Omega-3 Fatty Acid
... would still offer significant improvement of long-term cognitive recovery. In the present study, we employed the decline of spatial cognitive function as a main outcome after TBI to investigate the therapeutic efficacy of post-TBI n-3 PUFA treatment and the underlying mechanisms. Mice were subjected ...
... would still offer significant improvement of long-term cognitive recovery. In the present study, we employed the decline of spatial cognitive function as a main outcome after TBI to investigate the therapeutic efficacy of post-TBI n-3 PUFA treatment and the underlying mechanisms. Mice were subjected ...
Doehrty-McMahon 2009
... of cells, have some of these issues been addressed. The most commonly reported nonclathrincoated plasma membrane buds are known as caveolae (for “little caves”) (Figure 1). These flask-shaped invaginations exist on the surface of many mammalian cell types, are around 60–80 nm in diameter, and can con ...
... of cells, have some of these issues been addressed. The most commonly reported nonclathrincoated plasma membrane buds are known as caveolae (for “little caves”) (Figure 1). These flask-shaped invaginations exist on the surface of many mammalian cell types, are around 60–80 nm in diameter, and can con ...
FGF signalling: diverse roles during early vertebrate embryogenesis
... Stem zone. Population of cells in the posterior-most region of the epiblast in the chick and mouse that are undifferentiated and proliferative and give rise to either spinal cord or somitic mesoderm. Trophectoderm. The extra-embryonic ectoderm occupying the outer layer of the mammalian blastocyst. I ...
... Stem zone. Population of cells in the posterior-most region of the epiblast in the chick and mouse that are undifferentiated and proliferative and give rise to either spinal cord or somitic mesoderm. Trophectoderm. The extra-embryonic ectoderm occupying the outer layer of the mammalian blastocyst. I ...
AP Biology Unit 3 Introductory PP
... • Protobionts are aggregates of abiotically produced molecules surrounded by a membrane or membrane-like structure • Experiments demonstrate that protobionts could have formed spontaneously from abiotically produced organic compounds • For example, small membrane-bounded droplets called liposomes ca ...
... • Protobionts are aggregates of abiotically produced molecules surrounded by a membrane or membrane-like structure • Experiments demonstrate that protobionts could have formed spontaneously from abiotically produced organic compounds • For example, small membrane-bounded droplets called liposomes ca ...
MOLECULAR BASIS FOR MEMBRANE PHOSPHOLIPID
... to develop approaches to investigate the specific role phospholipids play in cellular functions. The majority of evidence establishing functions for phospholipids has been a secondary product of the study of cellular processes in in vitro reconstituted systems. This approach does yield important clu ...
... to develop approaches to investigate the specific role phospholipids play in cellular functions. The majority of evidence establishing functions for phospholipids has been a secondary product of the study of cellular processes in in vitro reconstituted systems. This approach does yield important clu ...
T cell co-stimulatory receptor CD28 is a primary target for
... canonical bull’s eye pattern with a center TCR island surrounded by CD28 and PD-1, with the latter partially excluded from the TCR rich zone (145 sec, Fig. 1B). Some degree of CD28 / PD-1 coclustering was also detected in the absence of pMHC, though the two coreceptors remain largely diffuse without ...
... canonical bull’s eye pattern with a center TCR island surrounded by CD28 and PD-1, with the latter partially excluded from the TCR rich zone (145 sec, Fig. 1B). Some degree of CD28 / PD-1 coclustering was also detected in the absence of pMHC, though the two coreceptors remain largely diffuse without ...
Label-Free Molecular Imaging of Living Cells
... applied to observe biological samples, such as the skin of a live mouse (Evans et al., 2005) at video rate. However even CARS does not provide background-free detection of signals. Light with the same wavelength as the CARS signal may also be produced without resonant effect to molecular vibrations ...
... applied to observe biological samples, such as the skin of a live mouse (Evans et al., 2005) at video rate. However even CARS does not provide background-free detection of signals. Light with the same wavelength as the CARS signal may also be produced without resonant effect to molecular vibrations ...
Plant responses to Agrobacterium tumefaciens and crown gall
... iaaH and iaaM transcripts by PCR in Agrobacterium cells of strain C58 and confirmed the earlier findings. It remains to be proven whether these genes are responsible for auxin production or if auxin is synthesized by a different mechanism in Agrobacterium cells. The mechanism for cytokinin biosynthesi ...
... iaaH and iaaM transcripts by PCR in Agrobacterium cells of strain C58 and confirmed the earlier findings. It remains to be proven whether these genes are responsible for auxin production or if auxin is synthesized by a different mechanism in Agrobacterium cells. The mechanism for cytokinin biosynthesi ...
Expression of biologically active mouse ciliary neutrophic factor
... The CNTF receptor (CNTFR) comprises three subunits: CNTFRa, leukemia inhibitory factor b receptor (LIFRb) and gp130 [40, 41]. CNTFRa is a glycosylphosphatidylinositol (GPI) - anchored protein, which can also be found in a soluble form (sCNTFRa) [42]. The binding of CNTF to membrane bound or soluble ...
... The CNTF receptor (CNTFR) comprises three subunits: CNTFRa, leukemia inhibitory factor b receptor (LIFRb) and gp130 [40, 41]. CNTFRa is a glycosylphosphatidylinositol (GPI) - anchored protein, which can also be found in a soluble form (sCNTFRa) [42]. The binding of CNTF to membrane bound or soluble ...
Heterotopic Neurons with Altered Inhibitory Synaptic Function in an
... each of these animal models, spontaneous seizures or an increased susceptibility to convulsant agents has been reported. Here we focused on rats exposed to MAM in utero because they are highly seizure susceptible (de Feo et al., 1995; Baraban and Schwartzkroin, 1996; Germano et al., 1996; Chevassus- ...
... each of these animal models, spontaneous seizures or an increased susceptibility to convulsant agents has been reported. Here we focused on rats exposed to MAM in utero because they are highly seizure susceptible (de Feo et al., 1995; Baraban and Schwartzkroin, 1996; Germano et al., 1996; Chevassus- ...
responses of cultured cardiac myocytes to lysosomotropic
... AO-positive granules could be visualized in myocytes exposed to the methylated L-amino acids for one or more hours and this staining may reflect the localization of the dye within endosomes. The treatment of cultures with AO and the amino acid methyl esters did not seriously affect the viability of ...
... AO-positive granules could be visualized in myocytes exposed to the methylated L-amino acids for one or more hours and this staining may reflect the localization of the dye within endosomes. The treatment of cultures with AO and the amino acid methyl esters did not seriously affect the viability of ...
Disruption of Mks1 localization to the mother centriole causes cilia
... some with a right-sided aortic arch (Fig. 1B,E). We also observed other visceral organ situs defects, including randomized left-right positioning of the stomach (data not shown), abnormal liver situs with some exhibiting symmetric midline liver (Fig. 1F), and polysplenia or asplenia (Fig. 1I and dat ...
... some with a right-sided aortic arch (Fig. 1B,E). We also observed other visceral organ situs defects, including randomized left-right positioning of the stomach (data not shown), abnormal liver situs with some exhibiting symmetric midline liver (Fig. 1F), and polysplenia or asplenia (Fig. 1I and dat ...
The regulation and plasticity of root hair patterning
... the absorptive area, particularly in the Pi-rich topsoil layer. The coordination of shoot and root responses involves trafficking of systemic signals, such as sugar, microRNAs and hormones, through the vasculature to tune the responses in roots (Lin et al., 2014). The morphological responses of root ...
... the absorptive area, particularly in the Pi-rich topsoil layer. The coordination of shoot and root responses involves trafficking of systemic signals, such as sugar, microRNAs and hormones, through the vasculature to tune the responses in roots (Lin et al., 2014). The morphological responses of root ...
Minutes LAS Curriculum and Requirements Committee Wednesday, April 18, 2007 – COH 2025A
... Present: Members – Mike Kisley, Debra Dew, Jim Eberhart, Sonja Braun-Sand, Suzanne MacAulay, Lynda Dickson. Ex-officio – Ruth Sansing, Rex Welshon, Sheryl Botts. A. ...
... Present: Members – Mike Kisley, Debra Dew, Jim Eberhart, Sonja Braun-Sand, Suzanne MacAulay, Lynda Dickson. Ex-officio – Ruth Sansing, Rex Welshon, Sheryl Botts. A. ...
A Ligand for CD5 Is CD5 - The Journal of Immunology
... Two receptors expressed primarily on T cells, CD5 and CD6, are linked genetically and are structurally similar, both containing three scavenger receptor cysteine-rich domains in their extracellular regions. A specific cell surface interaction for CD5 has been difficult to define at the molecular lev ...
... Two receptors expressed primarily on T cells, CD5 and CD6, are linked genetically and are structurally similar, both containing three scavenger receptor cysteine-rich domains in their extracellular regions. A specific cell surface interaction for CD5 has been difficult to define at the molecular lev ...
Acanthamoeba polyphaga Intracellular Infection of
... A small portion of the cells had already been lysed by 12 h postinfection. Only ⬃2% of the phagosomes had intact membranes with no signs of disruption of integrity in this time period (Fig. 2A; see also Fig. 8A). The lumen of the phagosomes was distended compared to that of 8-h-old phagosomes. Seven ...
... A small portion of the cells had already been lysed by 12 h postinfection. Only ⬃2% of the phagosomes had intact membranes with no signs of disruption of integrity in this time period (Fig. 2A; see also Fig. 8A). The lumen of the phagosomes was distended compared to that of 8-h-old phagosomes. Seven ...
Connecting muscles to tendons - Development
... Tendon determination: autonomous versus non-autonomous induction The precise connectivity between muscles, tendons and bones is crucial for optimal locomotion of the organism, yet the pathways involved in this process are poorly understood. Several mechanisms could underlie the accurate connectivity ...
... Tendon determination: autonomous versus non-autonomous induction The precise connectivity between muscles, tendons and bones is crucial for optimal locomotion of the organism, yet the pathways involved in this process are poorly understood. Several mechanisms could underlie the accurate connectivity ...
PDF + SI - Development - The Company of Biologists
... The 5kb PSE contains both an upstream element, PSE_a, as well as the previously described PSE_b switch enhancer reported to interact with the Eomes promoter during DE differentiation (Fig. S1A) (Beyer et al., 2013; Kartikasari et al., 2013). To investigate their functional activities in the context ...
... The 5kb PSE contains both an upstream element, PSE_a, as well as the previously described PSE_b switch enhancer reported to interact with the Eomes promoter during DE differentiation (Fig. S1A) (Beyer et al., 2013; Kartikasari et al., 2013). To investigate their functional activities in the context ...
The Lymphatic and Immune Systems
... 2 Antibodies bind to antigens on bacteria, marking the bacteria for destruction. (b) Differentiation and activity of B lymphocyte 1 B lymphocyte gives rise to plasma cell, which secretes antibodies. ...
... 2 Antibodies bind to antigens on bacteria, marking the bacteria for destruction. (b) Differentiation and activity of B lymphocyte 1 B lymphocyte gives rise to plasma cell, which secretes antibodies. ...
Applied Microbiology and Biotechnology
... acetate, lactate, valerate, fumarate, ethanol, glycerol and yeast extract (Xing et al. 2008). Alcaligenes faecalis, Enterococcus gallinarum and Pseudomonas aeruginosa are known to generate electricity by producing their own mediators, using glucose as an electron donor (Rabaey et al. 2004). To date, ...
... acetate, lactate, valerate, fumarate, ethanol, glycerol and yeast extract (Xing et al. 2008). Alcaligenes faecalis, Enterococcus gallinarum and Pseudomonas aeruginosa are known to generate electricity by producing their own mediators, using glucose as an electron donor (Rabaey et al. 2004). To date, ...
Sequential depolarization of root cortical and stelar cells induced by
... steady net K+ fluxes from the isolated tissue. The damaged cells are very ‘leaky’ for K+ (as one would expect from the c. 200-fold concentration gradient between the cytosol and the bath solution under our experimental conditions). The initial K+ efflux observed immediately after the isolation winds ...
... steady net K+ fluxes from the isolated tissue. The damaged cells are very ‘leaky’ for K+ (as one would expect from the c. 200-fold concentration gradient between the cytosol and the bath solution under our experimental conditions). The initial K+ efflux observed immediately after the isolation winds ...
Development and Characterization of New Species Cross
... gave a better understanding of the potential role of Sn and Sn-positive (Sn+ ) macrophages. Sn can be drastically upregulated on macrophages, monocytes, and monocyte-derived dendritic cells (DC) during conditions of inflammation [1–3,13,15,16]. It was shown that Sn+ -macrophages can act as antigen ( ...
... gave a better understanding of the potential role of Sn and Sn-positive (Sn+ ) macrophages. Sn can be drastically upregulated on macrophages, monocytes, and monocyte-derived dendritic cells (DC) during conditions of inflammation [1–3,13,15,16]. It was shown that Sn+ -macrophages can act as antigen ( ...
FKBP12-rapamycin-associated protein associates
... Fig. 3. Analysis of FRAP immune-complex and localization of FRAP by subcellular fractionation studies. (A) Identification of components of PDH complex in FRAP immune-complexes. Jurkat cells were lysed as described in Materials and Methods and the cell lysate was used to isolate FRAP immune-complexes ...
... Fig. 3. Analysis of FRAP immune-complex and localization of FRAP by subcellular fractionation studies. (A) Identification of components of PDH complex in FRAP immune-complexes. Jurkat cells were lysed as described in Materials and Methods and the cell lysate was used to isolate FRAP immune-complexes ...
Shift in GATA3 functions, and GATA3 mutations, control progression
... percent were cell-specific (Figure 2A), pointing to altered targets recognition by GATA3 following tumorigenesis. In both samples, 46% of GATA3 binding sites were inside or within 10 kbp of coding sequences (Figure 2B). Of these, among GO annotated genes [36], large groups are associated with cellul ...
... percent were cell-specific (Figure 2A), pointing to altered targets recognition by GATA3 following tumorigenesis. In both samples, 46% of GATA3 binding sites were inside or within 10 kbp of coding sequences (Figure 2B). Of these, among GO annotated genes [36], large groups are associated with cellul ...