COMMUNICATION Two categories of mammalian galactose
... isolated from the cells on avidin confirmed the presence of Kupffer cell receptor at the cell surface. It is possible that the Kupffer cell receptor requires the presence of accessory proteins not present in the fibroblasts to enable it to endocytose. However, this would be atypical of the C-type le ...
... isolated from the cells on avidin confirmed the presence of Kupffer cell receptor at the cell surface. It is possible that the Kupffer cell receptor requires the presence of accessory proteins not present in the fibroblasts to enable it to endocytose. However, this would be atypical of the C-type le ...
Assembly of AO and DHAS - Journal of Cell Science
... the AO and DHAS from the pellet (Fig. 1C) and no the only species that crosses the peroxisomal membrane. peroxisomal membrane (Fig. 1D). In summary, there is little Having shown that AO is imported as a monomer and DHAS cross contamination between cytosol (in the SUP), matrix and as a dimer, we next ...
... the AO and DHAS from the pellet (Fig. 1C) and no the only species that crosses the peroxisomal membrane. peroxisomal membrane (Fig. 1D). In summary, there is little Having shown that AO is imported as a monomer and DHAS cross contamination between cytosol (in the SUP), matrix and as a dimer, we next ...
The ring of life hypothesis for eukaryote origins is supported by
... cargo to the vacuole in eukaryotes. However, the ESCRT system is also known to have other functions such as eukaryotic cell abscission, viral budding, exosome secretion and autophagy [64]. These are not typical features of prokaryotes, so future work will have to properly elucidate their likely func ...
... cargo to the vacuole in eukaryotes. However, the ESCRT system is also known to have other functions such as eukaryotic cell abscission, viral budding, exosome secretion and autophagy [64]. These are not typical features of prokaryotes, so future work will have to properly elucidate their likely func ...
Insulin-Like Growth Factor and Potassium Depolarization Maintain
... targets of neuronal innervation (Oppenheim, 1991; Johnson and Deckworth, 1993). Several such factors have been identified in mammalian systems in recent years, and these include the neurotrophins: nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), neurotrophin-3, neurotrophin4/5, i ...
... targets of neuronal innervation (Oppenheim, 1991; Johnson and Deckworth, 1993). Several such factors have been identified in mammalian systems in recent years, and these include the neurotrophins: nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), neurotrophin-3, neurotrophin4/5, i ...
Hepatitis C Virus - Arteriosclerosis, Thrombosis, and Vascular Biology
... droplets can be secreted out of cells as nascent VLDL through exocytosis.14 In addition to generating lipid droplets in the ER lumen, MTP also stabilizes apoB during translation by transferring lipids to the nascent polypeptide chain of apoB.14,22 In the absence of this lipid transfer, the secretion ...
... droplets can be secreted out of cells as nascent VLDL through exocytosis.14 In addition to generating lipid droplets in the ER lumen, MTP also stabilizes apoB during translation by transferring lipids to the nascent polypeptide chain of apoB.14,22 In the absence of this lipid transfer, the secretion ...
Isoform 5 of PIPKIc regulates the endosomal trafficking and
... absent (Fig. 2A,B). Furthermore, the levels of endogenous Ncadherin and transferrin receptor (TfnR) were unaffected by the expression of either SNX5 or PIPKIci5, indicating that a general change in protein degradation was not occurring in these cells. To determine whether these observations were due ...
... absent (Fig. 2A,B). Furthermore, the levels of endogenous Ncadherin and transferrin receptor (TfnR) were unaffected by the expression of either SNX5 or PIPKIci5, indicating that a general change in protein degradation was not occurring in these cells. To determine whether these observations were due ...
The preplacodal region - Kings College
... specification of border derivatives. Msx1 is a direct mediator of BMP signalling and as such functions in promoting epidermal and repressing neural character during early stages of Xenopus development, thereby positioning the border between both tissues (Suzuki, et al., 1997; Feledy, et al., 1999; P ...
... specification of border derivatives. Msx1 is a direct mediator of BMP signalling and as such functions in promoting epidermal and repressing neural character during early stages of Xenopus development, thereby positioning the border between both tissues (Suzuki, et al., 1997; Feledy, et al., 1999; P ...
Cyclooxygenase-2 Contributes to N-Methyl-D-aspartate
... (COX; for a review, see Smith et al., 1991). There are two known COX isoforms, COX-1 and COX-2, which are 90% similar in amino acid sequence and 60% homologous (Smith and DeWitt 1995). Although the isoforms catalyze the same reaction, the genes encoding the different isoforms differ in their regulat ...
... (COX; for a review, see Smith et al., 1991). There are two known COX isoforms, COX-1 and COX-2, which are 90% similar in amino acid sequence and 60% homologous (Smith and DeWitt 1995). Although the isoforms catalyze the same reaction, the genes encoding the different isoforms differ in their regulat ...
Full Text
... specification of border derivatives. Msx1 is a direct mediator of BMP signalling and as such functions in promoting epidermal and repressing neural character during early stages of Xenopus development, thereby positioning the border between both tissues (Suzuki, et al., 1997; Feledy, et al., 1999; P ...
... specification of border derivatives. Msx1 is a direct mediator of BMP signalling and as such functions in promoting epidermal and repressing neural character during early stages of Xenopus development, thereby positioning the border between both tissues (Suzuki, et al., 1997; Feledy, et al., 1999; P ...
... the immunoglobulin superfamily (see below), whilst endothelial receptors for CD11c/CD18 have not yet been identified [29]. Mac-1 and CD11c/CD18 but not LFA-1 are also found in intracellular storage pools within neutrophils [30–32]. The majority of Mac-1 (75%) in resting neutrophils is localized in s ...
Full Text - Harvard University
... Gunflint-type assemblages are dominated by filamentous microfossils less than ca. 2.5 mm across (Gunflintia minuta) variously interpreted as cyanobacteria (oxygenic photosynthetic bacteria)11,16,17 or chemotrophic bacteria that oxidized iron11,14,18 or sulfur19. The G. minuta morphospecies may include ...
... Gunflint-type assemblages are dominated by filamentous microfossils less than ca. 2.5 mm across (Gunflintia minuta) variously interpreted as cyanobacteria (oxygenic photosynthetic bacteria)11,16,17 or chemotrophic bacteria that oxidized iron11,14,18 or sulfur19. The G. minuta morphospecies may include ...
Inducing chromosome pairing through premature condensation
... (DARTLRE) region of the cdk-like genes (Supplementary Fig. 1). Meiosis was compared in immature anthers collected from sense and antisense ODN-treated detached wheat tillers. In sense ODN-treated tillers, first and second divisions of meiosis appeared normal. Meiocytes within each locule were all sy ...
... (DARTLRE) region of the cdk-like genes (Supplementary Fig. 1). Meiosis was compared in immature anthers collected from sense and antisense ODN-treated detached wheat tillers. In sense ODN-treated tillers, first and second divisions of meiosis appeared normal. Meiocytes within each locule were all sy ...
Natural Product Anacardic Acid from Cashew Nut Shells
... extract, anacardic acid, has been shown to exert a variety of effects on both prokaryotic and eukaryotic cells (4, 5). Anacardic acid is a blanket term applied to a family of closely related compounds consisting of salicylic acid with a 15-carbon alkyl chain, which exist either in a fully saturated ...
... extract, anacardic acid, has been shown to exert a variety of effects on both prokaryotic and eukaryotic cells (4, 5). Anacardic acid is a blanket term applied to a family of closely related compounds consisting of salicylic acid with a 15-carbon alkyl chain, which exist either in a fully saturated ...
Cardiomyocyte Lineage Specification in€Adult Human Cardiac
... CARMEN, a long noncoding RNA associated with an enhancer located in the MIR-143/145 locus and target of NOTCH signaling. The CARMEN/MIR-145/143 axis represents, therefore, a promising target to favor production of cardiomyocytes in cell replacement therapies. (J Am Coll Cardiol Basic Trans Science 2 ...
... CARMEN, a long noncoding RNA associated with an enhancer located in the MIR-143/145 locus and target of NOTCH signaling. The CARMEN/MIR-145/143 axis represents, therefore, a promising target to favor production of cardiomyocytes in cell replacement therapies. (J Am Coll Cardiol Basic Trans Science 2 ...
Pascale G. Charest and Michel Bouvier Activation
... natural ligand, AVP (6). Among diverse mechanisms, -arrestin recruitment and receptor endocytosis have often been proposed to be implicated in the activation of these MAPKs by GPCR. Despite the growing recognition that activation of MAPK by GPCR plays important roles in downstream signaling events ...
... natural ligand, AVP (6). Among diverse mechanisms, -arrestin recruitment and receptor endocytosis have often been proposed to be implicated in the activation of these MAPKs by GPCR. Despite the growing recognition that activation of MAPK by GPCR plays important roles in downstream signaling events ...
... Given the increasing prevalence of cryptococcosis caused by Cryptococcus gattii (serotypes B and C) strains, there is a need for rapid and reliable tests that discriminate C. gattii from Cryptococcus neoformans (serotypes A, D, and AD). Seventy-two C. neoformans strains, sixty-seven C. gattii strain ...
PDF
... candidates. A gradient of the protein nerve growth factor can orient nerve growth (Gundersen & Barrett, 1980), while oriented cell shape changes and directional migration of leucocytes, for example, are induced by chemoattractant peptides released by bacteria (e.g. Schiffman, 1982). Xenopus myoblast ...
... candidates. A gradient of the protein nerve growth factor can orient nerve growth (Gundersen & Barrett, 1980), while oriented cell shape changes and directional migration of leucocytes, for example, are induced by chemoattractant peptides released by bacteria (e.g. Schiffman, 1982). Xenopus myoblast ...
i ANALYSIS OF THE ENU-3 PROTEIN FAMILY IN NERVOUS
... 1.1 General introduction and outline of thesis……….....…………………..………..1 1.2 Caenorhabditis elegans as a model organism ……………………………….…....4 1.3 Neuron structure and function …………………...……………………………….7 1.4 C.elegans nervous system…………………………..…..………………………….10 1.5 Growth cones, axon outgrowth and axon guida ...
... 1.1 General introduction and outline of thesis……….....…………………..………..1 1.2 Caenorhabditis elegans as a model organism ……………………………….…....4 1.3 Neuron structure and function …………………...……………………………….7 1.4 C.elegans nervous system…………………………..…..………………………….10 1.5 Growth cones, axon outgrowth and axon guida ...
Vaccinia Protein F12 Has Structural Similarity to Kinesin
... Vaccinia virus (VACV) uses microtubules for export of virions to the cell surface and this process requires the viral protein F12. Here we show that F12 has structural similarity to kinesin light chain (KLC), a subunit of the kinesin-1 motor that binds cargo. F12 and KLC share similar size, pI, hydr ...
... Vaccinia virus (VACV) uses microtubules for export of virions to the cell surface and this process requires the viral protein F12. Here we show that F12 has structural similarity to kinesin light chain (KLC), a subunit of the kinesin-1 motor that binds cargo. F12 and KLC share similar size, pI, hydr ...
Interplay between SCARECROW, GA and LIKE
... Genetic and epigenetic basis of ground tissue patterning 5 SCR does to the MGP promoter. The binding profiles for LHP1 and SCR overlap considerably. Next we performed quantitative RT–PCR and found that the expression levels of MGP and SCR are increased in the lhp1 mutant (Figure 2d), suggesting tha ...
... Genetic and epigenetic basis of ground tissue patterning 5 SCR does to the MGP promoter. The binding profiles for LHP1 and SCR overlap considerably. Next we performed quantitative RT–PCR and found that the expression levels of MGP and SCR are increased in the lhp1 mutant (Figure 2d), suggesting tha ...
Doubling Tyl Element Copy Number in Saccharomyces
... constructed using marked GAL/Tyl fusion plasmids. The strains maintain their high transposon copy number and overall genome structure in the absence of selection. The strains bearing extra T y l copies are surprisingly similar phenotypically to the parental strain. The results suggest that the limit ...
... constructed using marked GAL/Tyl fusion plasmids. The strains maintain their high transposon copy number and overall genome structure in the absence of selection. The strains bearing extra T y l copies are surprisingly similar phenotypically to the parental strain. The results suggest that the limit ...
Calcium Signaling and Homeostasis in Nuclei
... [Ca2+] concomitant with the first cytosolic Ca2+ peak was observed. In contrast, increasing the osmolarity elicited a smaller but identical biphasic response in cytosolic [Ca2+] without inducing changes in nuclear [Ca2+] (Pauly et al. 2001). In the same way, it has been shown that cryptogein, a poly ...
... [Ca2+] concomitant with the first cytosolic Ca2+ peak was observed. In contrast, increasing the osmolarity elicited a smaller but identical biphasic response in cytosolic [Ca2+] without inducing changes in nuclear [Ca2+] (Pauly et al. 2001). In the same way, it has been shown that cryptogein, a poly ...
Biological Science (BIOL)
... Laboratory sessions include: observations of animal behavior, required manipulations of live animals, and field trips. Three hours of lecture, one four-hour laboratory. Corequisite(s): BIOL 556L Restriction(s): Cannot enroll if Class is Undergraduate NCFD or Undergraduate NCFD or Freshman or Sophomo ...
... Laboratory sessions include: observations of animal behavior, required manipulations of live animals, and field trips. Three hours of lecture, one four-hour laboratory. Corequisite(s): BIOL 556L Restriction(s): Cannot enroll if Class is Undergraduate NCFD or Undergraduate NCFD or Freshman or Sophomo ...
1 Nucleoli: Composition, Function and Dynamics
... identified. In addition to the expected ribosomal and nucleolar proteins, a range of nonribosomal and non-nucleolar proteins including plant-specific proteins, proteins with unknown function, and splicing and translation factors was observed (Pendle et al., 2005). In particular, exon junction comple ...
... identified. In addition to the expected ribosomal and nucleolar proteins, a range of nonribosomal and non-nucleolar proteins including plant-specific proteins, proteins with unknown function, and splicing and translation factors was observed (Pendle et al., 2005). In particular, exon junction comple ...
Introduction: Keylevels of Biocommunication in Fungi
... The roles of some of these signalling molecules are as follows: (i) Mitogen activated protein kinase signalling (MAPK) is involved in cell integrity, cell wall construction, pheromones/mating and osmo-regulation (Dohlman and Slessareva 2006; Yu et al. 2008), (ii) the cyclic adenosine monophosphate c ...
... The roles of some of these signalling molecules are as follows: (i) Mitogen activated protein kinase signalling (MAPK) is involved in cell integrity, cell wall construction, pheromones/mating and osmo-regulation (Dohlman and Slessareva 2006; Yu et al. 2008), (ii) the cyclic adenosine monophosphate c ...