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Four-cell stage mouse blastomeres have different developmental
Four-cell stage mouse blastomeres have different developmental

... different fates, the question arises as to whether they are equivalent to each other. This could happen, for example, as a consequence of their spatial relationship per se or because they inherit different properties when they divide. Indeed it has been proposed that an equatorial division of the tw ...
Comparison of two methods for the diagnosis of chronic
Comparison of two methods for the diagnosis of chronic

... arthritis, osteomyelitis, cellulitis, and impetigo. Granulomas form due to the accumulation of white blood cells in the infected areas, even in cases when antibiotics have eliminated the infection-causing organism. Patients with CGD are especially susceptible to infections caused by catalase positiv ...
The Majority of Yeast UPF1 Co-localizes with Polyribosomes in the
The Majority of Yeast UPF1 Co-localizes with Polyribosomes in the

... In Saccharomyces cerevisiae the UPF1 protein is required for nonsense-mediated mRNA decay, the accelerated turnover of mRNAs containing a nonsense mutation. Several lines of evidence suggest that translation plays an important role in the mechanism of nonsense mRNA decay, including a previous report ...
Subcellular localization of peroxidase in tomato fruit skin and the
Subcellular localization of peroxidase in tomato fruit skin and the

... The use of high ionic strength buffers to elute `wallbound' peroxidases is a standard procedure used to examine ionically bound cell wall enzymes (Ferrer et al., 1991; Andrews et al., 2000; Quiroga et al., 2000). However, this procedure may not distinguish between peroxidases bound to the cell wall ...
AP #15L1 - Defiance City Schools
AP #15L1 - Defiance City Schools

...  It can be injured by trauma, especially if it is swollen or enlarged (protected some by ribs) It will enlarge (splenomegaly) during some diseases, like mono, scarlet fever, syphilis, typhoid fever ...
The Pathogen-Actin Connection: A Platform for Defense Signaling in
The Pathogen-Actin Connection: A Platform for Defense Signaling in

... Access provided by Michigan State University Library on 07/06/16. For personal use only. ...
PDF
PDF

... Bmp4 by qPCR (Fig. 5, right panels). Lef1, Ptch1 and Bmp4 mRNA levels were significantly reduced in tongues derived from WT1-KO embryos as compared with wild type. We conclude that WT1 is essential for the normal development of the peripheral taste system and that it is first required during initial ...
Vacuolar transporters and their essential role in plant metabolism
Vacuolar transporters and their essential role in plant metabolism

... blue, transporters for water and organic solutes; orange, inorganic anion channels and transporters; green, cation transporters; pink, secondary metabolite transporters. 1, V-PPase; 2, V-ATPase; 3, MRP-type ABC transporter; 4, P-type Ca2+ pump; 5–7, tonoplastic intrinsic proteins (TIPs) are permeabl ...
Bactericidal, Bacteriolytic, and Antibacterial Virulence Activities of
Bactericidal, Bacteriolytic, and Antibacterial Virulence Activities of

... cell wall of S. mutans [11]. This present study revealed that treatment of S. pyogenes cells with B. pandurata extract resulted in cell lysis. A possible mechanism of action may be associated with cell wall and membrane damage. Proteases have long been considered as virulence factors for organisms a ...
Pathogenic potential of Aeromonas hydrophila isolated from surface
Pathogenic potential of Aeromonas hydrophila isolated from surface

... species are increasingly recognized as enteric pathogens; they possess several virulence factors associated with human disease, and represent a serious public health concern. In the present study, putative virulence traits of Aeromonas hydrophila isolates collected from different natural surface wat ...
Localization of retinitis pigmentosa 2 to cilia is regulated by Importin 2
Localization of retinitis pigmentosa 2 to cilia is regulated by Importin 2

... trafficking of retinitis pigmentosa 2 (RP2, also known as protein XRP2) to the cilia. RP2 is an X-linked gene that, when mutated, gives rise to retinitis pigmentosa (Hardcastle et al., 1999). The RP2 gene encodes a 350 residue polypeptide that appears to be ubiquitously expressed. Previous work has ...
The Glial Cell–Derived Neurotrophic Factor Signaling Pathway
The Glial Cell–Derived Neurotrophic Factor Signaling Pathway

... Gerber, 1997). This structural information has made it possible to identify the surface residues in GDNF that are responsible for mediating interactions with GFR1. The structural information has guided experiments in which domains are swapped between GDNF family members. Individual amino acids with ...
Increased Susceptibility of the Sickle Cell Membrane
Increased Susceptibility of the Sickle Cell Membrane

... Effects of ascorbate and desferal on tBHP inhibition of normal and sickle cell membrane Ca2+ + MgF+-ATPase. Treatment of white erythrocyte membranes with tBHP (0.5 mmol/L) for 30 minutes did not result in significant loss of enzyme activity or formation of MDA. Therefore, to assess the effects of as ...
Characterization of a 30S Ribsomal Subunit Intermediate Found in
Characterization of a 30S Ribsomal Subunit Intermediate Found in

Staphylococcus δ-toxin induces allergic skin disease by
Staphylococcus δ-toxin induces allergic skin disease by

... enriched in the culture supernatant of S. aureus and was sensitive to heat, phenol/chloroform extraction and protease K treatment (Supplementary Fig. 2a). Furthermore, the MC degranulation-inducing factor bound to both diethylaminoethyl and carboxymethyl cellulose matrices and was present in the voi ...
ELM1 is required for multidrug resistance in
ELM1 is required for multidrug resistance in

... state (ASANO et al. 2005; HARVEY et al. 2005). Additional kinases are involved in the regulation of transition from G2 to mitosis. ELM1 (elongated morphology 1) encodes a serine/threonine protein kinase, and cells harboring elm1Δ exhibit elongated filamentous growth, an indication of G2/M delay (KOE ...
Type-IV Antifreeze Proteins are Essential for Epiboly and
Type-IV Antifreeze Proteins are Essential for Epiboly and

... Many organisms in extremely cold environments such as the Antarctic Pole have evolved antifreeze molecules to prevent ice formation. There are four types of antifreeze proteins (AFPs). Type-IV antifreeze proteins (AFP4s) are present also in certain temperate and even tropical fish, which has raised ...
Physical interaction between pRb and cdk9/cyclinT2 complex
Physical interaction between pRb and cdk9/cyclinT2 complex

... all bind and/or phosphorylate pRb during di€erent phases of the cell cycle (Ezhevsky et al., 1997; Hatakeyama et al., 1994; Lundberg and Weinberg, 1998; Pan et al., 2001). The retinoblastoma gene codes for a 105 kD nuclear protein that is regulated by phosphorylation. Depending on the amount of phos ...
7 - Dynamic Microtubules and the Texture of Plant Cell Walls
7 - Dynamic Microtubules and the Texture of Plant Cell Walls

... transverse “hoops.” However, as early as the 1950s, Roelofsen had to address observations from a range of higher plant cells that cellulose microfibrils are not always transverse; that is, perpendicular to the growth axis (Roelofsen, 1958). In the same year, Setterfield and Bayley concluded that thr ...
Growing models of vertebrate limb development - ICB-USP
Growing models of vertebrate limb development - ICB-USP

... (PD), running in the human arm from shoulder to digits; the anteroposterior (AP), from thumb to the little finger; and dorsoventral (DV), from the back of the hand to the palm. Much of the classical work on vertebrate limb development has been carried out in chicken embryos because the developing wi ...
Ultrastructure of the Epidermal Cell Wall and Cuticle of Tomato Fruit
Ultrastructure of the Epidermal Cell Wall and Cuticle of Tomato Fruit

... local increases of cuticle material since cuticle thickness was not altered in these areas. At anthesis, ...
Evaluation of peptide-mediated nucleic acid delivery
Evaluation of peptide-mediated nucleic acid delivery

... systems as they possess the above mentioned characteristics (28). Furthermore, they are easy to produce, relatively stable, non-toxic and non-immunogenic (2,23). Peptides can be categorized, depending on their function, as: DNA-condensing peptides, which condense nucleic acids, cell-penetrating pept ...
ETS-dependent regulation of a distal Gata4 cardiac enhancer
ETS-dependent regulation of a distal Gata4 cardiac enhancer

... mice lacking GATA4 in the myocardium display defective cardiomyocyte proliferation and embryonic lethality (Rojas et al., 2008; Zeisberg et al., 2005). Mice lacking Gata4 in the endothelium have defective endocardial cushion development and die around E12.5 of apparent heart failure (Rivera-Felician ...
The head organizer in Hydra
The head organizer in Hydra

... and McClay, 2006). The expression of several genes involved in the canonical Wnt pathway in Hydra suggested that this pathway plays a role in the Hydra organizer. HyWnt3, TCF and beta-catenin are expressed in the hypostome of the adult (Hobmayer et al., 2000; Broun et al., 2005). Subsequently, it wa ...
Bioreactor landfills: experimental and field results
Bioreactor landfills: experimental and field results

... distribution of the recirculated leachate. The nominal size of the gravel used for both filter layers range from 19 to 38 mm. Finally, the bioreactor cell covers were placed on top of each cell, and the whole unit was sealed using construction type sealant. The protruding ends of the gas collection w ...
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Amitosis

Amitosis (a- + mitosis) is absence of mitosis, the usual form of cell division in the cells of eukaryotes. There are several senses in which eukaryotic cells can be amitotic. One refers to capability for non-mitotic division and the other refers to lack of capability for division. In one sense of the word, which is now mostly obsolete, amitosis is cell division in eukaryotic cells that happens without the usual features of mitosis as seen on microscopy, namely, without nuclear envelope breakdown and without formation of mitotic spindle and condensed chromosomes as far as microscopy can detect. However, most examples of cell division formerly thought to belong to this supposedly ""non-mitotic"" class, such as the division of unicellular eukaryotes, are today recognized as belonging to a class of mitosis called closed mitosis. A spectrum of mitotic activity can be categorized as open, semi-closed, and closed mitosis, depending on the fate of the nuclear envelope. An exception is the division of ciliate macronucleus, which is not mitotic, and the reference to this process as amitosis may be the only legitimate use of the ""non-mitotic division"" sense of the term today. In animals and plants which normally have open mitosis, the microscopic picture described in the 19th century as amitosis most likely corresponded to apoptosis, a process of programmed cell death associated with fragmentation of the nucleus and cytoplasm. Relatedly, even in the late 19th century cytologists mentioned that in larger life forms, amitosis is a ""forerunner of degeneration"".Another sense of amitotic refers to cells of certain tissues that are usually no longer capable of mitosis once the organism has matured into adulthood. In humans this is true of various muscle and nerve tissue types; if the existing ones are damaged, they cannot be replaced with new ones of equal capability. For example, cardiac muscle destroyed by heart attack and nerves destroyed by piercing trauma usually cannot regenerate. In contrast, skin cells are capable of mitosis throughout adulthood; old skin cells that die and slough off are replaced with new ones. Human liver tissue also has a sort of dormant regenerative ability; it is usually not needed or expressed but can be elicited if needed.
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