Pepsin-Mediated Processing of the Cytoplasmic Histone H2A to
... encode antimicrobial peptides is tissue specific. Antimicrobial peptides can function intracellularly, as in circulating leukocytes or in the external environment after release by secretory cells and other granulated epithelia (8). Certain antimicrobial peptides have diverse functions beyond microbi ...
... encode antimicrobial peptides is tissue specific. Antimicrobial peptides can function intracellularly, as in circulating leukocytes or in the external environment after release by secretory cells and other granulated epithelia (8). Certain antimicrobial peptides have diverse functions beyond microbi ...
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... unique mode of cytoplasmic inheritance. Each organelle has multiple copies of a covalently closed circular DNA genome (mtDNA). The entire protein coding capacity of mtDNA is devoted to the synthesis of 13 essential subunits of the inner membrane complexes of the respiratory apparatus. Thus the major ...
... unique mode of cytoplasmic inheritance. Each organelle has multiple copies of a covalently closed circular DNA genome (mtDNA). The entire protein coding capacity of mtDNA is devoted to the synthesis of 13 essential subunits of the inner membrane complexes of the respiratory apparatus. Thus the major ...
Transcriptional Paradigms in Mammalian Mitochondrial Biogenesis
... unique mode of cytoplasmic inheritance. Each organelle has multiple copies of a covalently closed circular DNA genome (mtDNA). The entire protein coding capacity of mtDNA is devoted to the synthesis of 13 essential subunits of the inner membrane complexes of the respiratory apparatus. Thus the major ...
... unique mode of cytoplasmic inheritance. Each organelle has multiple copies of a covalently closed circular DNA genome (mtDNA). The entire protein coding capacity of mtDNA is devoted to the synthesis of 13 essential subunits of the inner membrane complexes of the respiratory apparatus. Thus the major ...
Kinetics of MPF and histone H1 kinase activity differ during the G2
... measuring the capacity of oocytes at different stages of maturation to induce nuclear membrane breakdown and chromatin condensation when fused to a dbcAMP arrested immature fusion partner. Our results presented in Table 1 support those of Hashimoto and Kishimoto (1988) who used a starfish assay syst ...
... measuring the capacity of oocytes at different stages of maturation to induce nuclear membrane breakdown and chromatin condensation when fused to a dbcAMP arrested immature fusion partner. Our results presented in Table 1 support those of Hashimoto and Kishimoto (1988) who used a starfish assay syst ...
Paralytic Shellfish Poisoning Toxins: Biochemistry and Origin Masaaki Kodama
... Plankton feeders such as bivalves often become toxic. Human consumption of the toxic bivalve causes severe food poisoning, including paralytic shellfish poisoning (PSP) which is the most dangerous because of the acuteness of the symptoms, high fatality and wide distribution throughout the world. Acc ...
... Plankton feeders such as bivalves often become toxic. Human consumption of the toxic bivalve causes severe food poisoning, including paralytic shellfish poisoning (PSP) which is the most dangerous because of the acuteness of the symptoms, high fatality and wide distribution throughout the world. Acc ...
What is SN PER® i
... Chlorine Dioxide (CLO2): o Chlorine Dioxide (CLO2) is an extremely effective and powerful biocide that has been used for many years, exhibiting rapid kill over a wide range of organisms. o It does not form chlorinated molecules in the presence of organics and is efficacious over a wide pH range o Al ...
... Chlorine Dioxide (CLO2): o Chlorine Dioxide (CLO2) is an extremely effective and powerful biocide that has been used for many years, exhibiting rapid kill over a wide range of organisms. o It does not form chlorinated molecules in the presence of organics and is efficacious over a wide pH range o Al ...
Unusual micro-organisms from unusual habitats
... summarized in Table 1. Several other genera have recently been reported: Halovivax asiaticus (Castillo et al., 2006) and ‘Halostagnum larsenii’ (A. M. Castillo, M. C. Gutierrez, M. Kamekura, Y. Xue, Y. Ma, D. A. Cowan, B. E. Jones, W. D. Grant and A. Ventosa, manuscript in preparation) were isolated ...
... summarized in Table 1. Several other genera have recently been reported: Halovivax asiaticus (Castillo et al., 2006) and ‘Halostagnum larsenii’ (A. M. Castillo, M. C. Gutierrez, M. Kamekura, Y. Xue, Y. Ma, D. A. Cowan, B. E. Jones, W. D. Grant and A. Ventosa, manuscript in preparation) were isolated ...
Toll-like receptors: resent advances, open questions and
... 1. expression verified by immunoblot 2. function tested using available positive controls ...
... 1. expression verified by immunoblot 2. function tested using available positive controls ...
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... In plant cells, the main organelles of the endomembrane system are the ER [38], the Golgi, comprised of numerous dispersed Golgi stacks called dictyosomes [39] and the trans-Golgi network (TGN) [40], multivesicular bodies/prevacuolar compartment (MVB/PVC) [41], lytic and protein storage vacuoles (LV ...
... In plant cells, the main organelles of the endomembrane system are the ER [38], the Golgi, comprised of numerous dispersed Golgi stacks called dictyosomes [39] and the trans-Golgi network (TGN) [40], multivesicular bodies/prevacuolar compartment (MVB/PVC) [41], lytic and protein storage vacuoles (LV ...
vilnius university
... these components, leading to more severe suppression of antitumor immunity thus making more favourable conditions for tumor progression. Hence, it is likely that antitumor immunotherapy may be effective only when its prescription is based on immune system parameters, reflecting the nature of antitum ...
... these components, leading to more severe suppression of antitumor immunity thus making more favourable conditions for tumor progression. Hence, it is likely that antitumor immunotherapy may be effective only when its prescription is based on immune system parameters, reflecting the nature of antitum ...
Charakterisierung peroxisomaler und Lipid
... Fig. 1.1.1.2 Induction of peroxisomes in yeast species and filamentous fungi. Peroxisomes can have highly variable sizes and shapes. Furthermore, they can be present in clusters but can also be dispersed throughout the cytoplasm. A) Aspergillus tamarii cell grown on oleate showing peroxisomes. In ad ...
... Fig. 1.1.1.2 Induction of peroxisomes in yeast species and filamentous fungi. Peroxisomes can have highly variable sizes and shapes. Furthermore, they can be present in clusters but can also be dispersed throughout the cytoplasm. A) Aspergillus tamarii cell grown on oleate showing peroxisomes. In ad ...
Modulatory effects of histamine on cat carotid body chemoreception
... chemosensory discharges was assessed using in vitro perfused or superfused CB preparations, which allow the isolation of vascular effects. The superfused CB preparation has been used to study chemoreceptor function without the interference of vascular control (Alcayaga et al., 1988; Eyzaguirre and K ...
... chemosensory discharges was assessed using in vitro perfused or superfused CB preparations, which allow the isolation of vascular effects. The superfused CB preparation has been used to study chemoreceptor function without the interference of vascular control (Alcayaga et al., 1988; Eyzaguirre and K ...
"VESICLE IN A BASKET" A Morphological Study of
... occurs first on the outer surface of the membrane, even though the bristles are located on the cytoplasmic side of the membrane . Since the coated vesicles are distinguished by the possession of hairlike material projecting from both sides of the membrane, a consideration of the intercalated unit me ...
... occurs first on the outer surface of the membrane, even though the bristles are located on the cytoplasmic side of the membrane . Since the coated vesicles are distinguished by the possession of hairlike material projecting from both sides of the membrane, a consideration of the intercalated unit me ...
Rho signaling pathway and apical constriction in the - ICB-USP
... (Fig. 3e–g). In addition, after CD treatment, although we did observe a slight increase in the number of picnotic nuclei in the optic vesicle, these were not detected in the lens placode. Thus, we exclude the possibility that our phenotype is generated by a toxic effect of the drugs and conclude tha ...
... (Fig. 3e–g). In addition, after CD treatment, although we did observe a slight increase in the number of picnotic nuclei in the optic vesicle, these were not detected in the lens placode. Thus, we exclude the possibility that our phenotype is generated by a toxic effect of the drugs and conclude tha ...
Photoactivatable GFP tagging cassettes for protein
... insights into the steady state distribution of the protein over time. However, in order to track protein movement within the cell, more complex imaging experiments, such as fluorescence recovery after photobleaching (FRAP), are required. FRAP is traditionally performed by selectively photobleaching ...
... insights into the steady state distribution of the protein over time. However, in order to track protein movement within the cell, more complex imaging experiments, such as fluorescence recovery after photobleaching (FRAP), are required. FRAP is traditionally performed by selectively photobleaching ...
Targets hidden by fibrin networks still need to find their place in the
... The treatment of rheumatoid arthritis has undergone a huge revolution in the past two decades with the incoming of biological therapies, which have been designed out of a better understanding of pathogenic mechanisms. However, while these compounds successfully prevent -or at least slow down- joint ...
... The treatment of rheumatoid arthritis has undergone a huge revolution in the past two decades with the incoming of biological therapies, which have been designed out of a better understanding of pathogenic mechanisms. However, while these compounds successfully prevent -or at least slow down- joint ...
ABSTRACT Title of Dissertation: GENETIC REGULATION OF AUTOPHAGIC CELL... Sudeshna Dutta, Doctor of Philosophy, 2008
... multiple cellular processes during metamorphosis in Drosophila, including cell differentiation, morphogenesis and death. E93 is necessary and sufficient for larval tissue cell death during metamorphosis, including autophagic cell death of salivary glands. Here we characterize new mutant alleles of ...
... multiple cellular processes during metamorphosis in Drosophila, including cell differentiation, morphogenesis and death. E93 is necessary and sufficient for larval tissue cell death during metamorphosis, including autophagic cell death of salivary glands. Here we characterize new mutant alleles of ...
Polyphosphate-ATP Amplification Technology: Principle and its
... USA) at 4°C. The beads were then removed from the solution with a magnet and resuspended in the PBS buffer containing 1% BSA. These steps were repeated three times and resuspended in the PBS buffer containing 1% BSA and 0.02% NaN3. Microbial cells that grew on nutrient medium were diluted with the PBS ...
... USA) at 4°C. The beads were then removed from the solution with a magnet and resuspended in the PBS buffer containing 1% BSA. These steps were repeated three times and resuspended in the PBS buffer containing 1% BSA and 0.02% NaN3. Microbial cells that grew on nutrient medium were diluted with the PBS ...
- Department of Biosystems Science and
... phosphorylate Hsp90 along with other pausing factors (Figure 2) and this step may be necessary for efficient gene activation. Additionally, Hsp90 may be acetylated or methylated by a myriad of chromatin-modifying enzymes located at promoters. Cytosolic isoforms of Hsp90 are known to be regulated by ...
... phosphorylate Hsp90 along with other pausing factors (Figure 2) and this step may be necessary for efficient gene activation. Additionally, Hsp90 may be acetylated or methylated by a myriad of chromatin-modifying enzymes located at promoters. Cytosolic isoforms of Hsp90 are known to be regulated by ...
Spotlight on the microbes that produce heat shock protein 90
... 3. The discovery of natural product inhibitors of heat shock protein 90 The appreciation that Hsp90 might be a valuable drug target was initially slow in coming. It was initiated by studies on the actions of benzoquinone ansamycins (table 1), actinomycete-derived antibiotics of very closely related ...
... 3. The discovery of natural product inhibitors of heat shock protein 90 The appreciation that Hsp90 might be a valuable drug target was initially slow in coming. It was initiated by studies on the actions of benzoquinone ansamycins (table 1), actinomycete-derived antibiotics of very closely related ...
Storage lipids of yeasts: a survey of nonpolar lipid metabolism in
... Biosynthesis and storage of nonpolar lipids, such as triacylglycerols (TG) and steryl esters (SE), have gained much interest during the last decades because defects in these processes are related to severe human diseases. The baker’s yeast Saccharomyces cerevisiae has become a valuable tool to study ...
... Biosynthesis and storage of nonpolar lipids, such as triacylglycerols (TG) and steryl esters (SE), have gained much interest during the last decades because defects in these processes are related to severe human diseases. The baker’s yeast Saccharomyces cerevisiae has become a valuable tool to study ...
Induction of stable ER–plasma-membrane junctions by Kv2.1
... that Kv2.1 induces a true ER–plasma-membrane junction with a <20 nm gap between the two membranes (Carrasco and Meyer, 2011; Orci et al., 2009). Thus, in order to examine the spatial relationship between Kv2.1 clusters on the plasma membrane and the underlying cER at high resolution, we used immuno- ...
... that Kv2.1 induces a true ER–plasma-membrane junction with a <20 nm gap between the two membranes (Carrasco and Meyer, 2011; Orci et al., 2009). Thus, in order to examine the spatial relationship between Kv2.1 clusters on the plasma membrane and the underlying cER at high resolution, we used immuno- ...
Asthma and Eczema
... eczema in humans produced TSLP ( thymic stromal lymphopoietin) and developed asthma Mice with normal skin but overproduced TSLP also developed asthma ...
... eczema in humans produced TSLP ( thymic stromal lymphopoietin) and developed asthma Mice with normal skin but overproduced TSLP also developed asthma ...