Introduction Wnt signaling in development
... that controls its stability. In the absence of Wnt signaling, this complex, which consists of the scaffolding protein Axin, the tumor suppressor gene product APC and the protein kinases Casein kinase Iα and GSK3β, targets β-catenin for ubiquitination and degradation by the proteasome. Binding of Wnt ...
... that controls its stability. In the absence of Wnt signaling, this complex, which consists of the scaffolding protein Axin, the tumor suppressor gene product APC and the protein kinases Casein kinase Iα and GSK3β, targets β-catenin for ubiquitination and degradation by the proteasome. Binding of Wnt ...
Transcription mechanisms
... mechanisms involved in transcription are conserved among eukaryotes, including C. elegans. Recent studies in various systems have revealed that this apparatus is not controlled through a simple on/off “switch” at the promoter, and that the factors and mechanisms involved in transcription are instead ...
... mechanisms involved in transcription are conserved among eukaryotes, including C. elegans. Recent studies in various systems have revealed that this apparatus is not controlled through a simple on/off “switch” at the promoter, and that the factors and mechanisms involved in transcription are instead ...
Datasheet Blank Template - Santa Cruz Biotechnology
... morphogen, dorsal. Both proteins specifically bind to DNA sequences that are the same or slight variations of the 10 bp κB sequence in the immunoglobulin κ light chain enhancer. This same sequence is also present in a number of other cellular and viral enhancers. The DNA binding activity of NFκB is ...
... morphogen, dorsal. Both proteins specifically bind to DNA sequences that are the same or slight variations of the 10 bp κB sequence in the immunoglobulin κ light chain enhancer. This same sequence is also present in a number of other cellular and viral enhancers. The DNA binding activity of NFκB is ...
Advances in Genetics - Department of Biology
... channel families, DEG/ENaC channels have evolved to serve many different physiological functions, acting as ionotropic receptors to diverse extracellular stimuli. Although amiloride-sensitive sodium currents from various epithelial tissues have been recorded since the early 1970s, the genes encoding ...
... channel families, DEG/ENaC channels have evolved to serve many different physiological functions, acting as ionotropic receptors to diverse extracellular stimuli. Although amiloride-sensitive sodium currents from various epithelial tissues have been recorded since the early 1970s, the genes encoding ...
Peptides that mimic Candida albicans–derived β
... 96-well plates and incubated with serial dilutions of DJ2.8 (filled bars), 5B2 (cross-hatched bars), or CA1 (open bars). After washing, bound mAbs were revealed with the corresponding antiserum and absorbance was measured. Results are expressed as the mean ± SD of triplicate determinations from one ...
... 96-well plates and incubated with serial dilutions of DJ2.8 (filled bars), 5B2 (cross-hatched bars), or CA1 (open bars). After washing, bound mAbs were revealed with the corresponding antiserum and absorbance was measured. Results are expressed as the mean ± SD of triplicate determinations from one ...
recommendations for tissue preparation and formalin or
... alter the quality of molecular analytes. A recent report recommends that tissue not be fixed for more than 36hrs to avoid overfixation and excessive cross-linking. We have also found that extended fixation can cause excessive brittleness of paraffin-embedded mouse tissues, which are inherently “ ...
... alter the quality of molecular analytes. A recent report recommends that tissue not be fixed for more than 36hrs to avoid overfixation and excessive cross-linking. We have also found that extended fixation can cause excessive brittleness of paraffin-embedded mouse tissues, which are inherently “ ...
The ultrastructure of a doliolid and a copepod
... Calanoid copepods on average usually produce fecal pellets at lower rates than D. gegenbauri gonozooids. Females of the copepod Eucalanus pileatus produce 2 pellets h21 compared with the 6 – 8 pellets h21 produced by a large gonozooid, both zooplankters being of similar weight i.e. 20– 25 mg C ind ...
... Calanoid copepods on average usually produce fecal pellets at lower rates than D. gegenbauri gonozooids. Females of the copepod Eucalanus pileatus produce 2 pellets h21 compared with the 6 – 8 pellets h21 produced by a large gonozooid, both zooplankters being of similar weight i.e. 20– 25 mg C ind ...
New TURF for TIRF - Stowers Institute for Medical Research
... fold brighter than CFP. CFP emission also bleeds into the YFP channel (i.e. there will always be some “FRET” signal). ...
... fold brighter than CFP. CFP emission also bleeds into the YFP channel (i.e. there will always be some “FRET” signal). ...
An autophagy-related kinase is essential for the symbiotic
... including pollen and root hairs (Welters et al., 1994; Lee et al., 2008a; Lee et al., 2008b). In the roots of 2-day-old P. vulgaris seedlings, the relative accumulation of PI3K transcript was higher (5.4-fold) in the root hairs, the site of rhizobial entry into the root, and in the root apex (4.1-fo ...
... including pollen and root hairs (Welters et al., 1994; Lee et al., 2008a; Lee et al., 2008b). In the roots of 2-day-old P. vulgaris seedlings, the relative accumulation of PI3K transcript was higher (5.4-fold) in the root hairs, the site of rhizobial entry into the root, and in the root apex (4.1-fo ...
atlas of dengue viruses morphology and morphogenesis
... borne viral disease in the world, along the last two decades and every effort to better understand its replication and morphogenesis should be encouraged. We consider this book an excellent contribution in these aspects. This publication is dedicated to the Instituto Oswaldo Cruz, in its Centenary a ...
... borne viral disease in the world, along the last two decades and every effort to better understand its replication and morphogenesis should be encouraged. We consider this book an excellent contribution in these aspects. This publication is dedicated to the Instituto Oswaldo Cruz, in its Centenary a ...
Interaction of PIN and PGP transport mechanisms in auxin
... had retarded root growth (Fig. 2F,R). This effect was stronger at increased concentrations of oestradiol, supporting the rate-limiting function of PIN proteins (Fig. 2R). Immunolocalization confirmed that ectopically expressed PIN1 was localized predominantly on the basal side of root epidermal cell ...
... had retarded root growth (Fig. 2F,R). This effect was stronger at increased concentrations of oestradiol, supporting the rate-limiting function of PIN proteins (Fig. 2R). Immunolocalization confirmed that ectopically expressed PIN1 was localized predominantly on the basal side of root epidermal cell ...
Guard cell-specific inhibition of Arabidopsis MPK3 expression
... membrane calcium channels in ABA-induced stomatal closure (Pei et al., 2000). Plasma membrane NADPH oxidases have been identified as a source of ROS necessary for stomatal closure, as the double mutant atrbohD/F is partially impaired in ABA-induced stomatal closure, and in the activation of calcium ...
... membrane calcium channels in ABA-induced stomatal closure (Pei et al., 2000). Plasma membrane NADPH oxidases have been identified as a source of ROS necessary for stomatal closure, as the double mutant atrbohD/F is partially impaired in ABA-induced stomatal closure, and in the activation of calcium ...
Molecular Structure and Physiological Function of Chloride Channels
... nels because Cl is the most abundant anion in organisms and hence is the predominant permeating species under most circumstances. Cl⫺ channel gating may depend on the transmembrane voltage (in voltage-gated channels), on cell swelling, on the binding of signaling molecules (as in ligand-gated anion ...
... nels because Cl is the most abundant anion in organisms and hence is the predominant permeating species under most circumstances. Cl⫺ channel gating may depend on the transmembrane voltage (in voltage-gated channels), on cell swelling, on the binding of signaling molecules (as in ligand-gated anion ...
Vocab smack-down
... • Sit down quickly and quietly if you would like to play Vocab Smack-Down • Get out your VOCAB HW (Flashcards or written definitions and pictures on paper) • STUDY for a few minutes SILENTLY ...
... • Sit down quickly and quietly if you would like to play Vocab Smack-Down • Get out your VOCAB HW (Flashcards or written definitions and pictures on paper) • STUDY for a few minutes SILENTLY ...
Outer Membrane Vesicle-Mediated Export of
... natural inhabitant of estuarine and coastal waters throughout world. This bacterium can survive in conditions of varying temperature, pH, and salinity. It can also survive in the presence of bacteriovorous predators such as ciliates and flagellates [3,4]. Secreted cholera toxin (CTX) is a major viru ...
... natural inhabitant of estuarine and coastal waters throughout world. This bacterium can survive in conditions of varying temperature, pH, and salinity. It can also survive in the presence of bacteriovorous predators such as ciliates and flagellates [3,4]. Secreted cholera toxin (CTX) is a major viru ...
Location and Size of Dopaminergic and Serotonergic Cell
... nigra (SN), ventral tegmental area (VTA), and retrorubral field (RrF) project to the striatum, cortex, and nucleus accumbens (Björklund and Lindvall, 1984). They modulate a variety of functions, such as movement, rewarding, cognition, and feeding (Zhou and Palmiter, 1995; Cooper et al., 2001). A dy ...
... nigra (SN), ventral tegmental area (VTA), and retrorubral field (RrF) project to the striatum, cortex, and nucleus accumbens (Björklund and Lindvall, 1984). They modulate a variety of functions, such as movement, rewarding, cognition, and feeding (Zhou and Palmiter, 1995; Cooper et al., 2001). A dy ...
- WRAP: Warwick Research Archive Portal
... Design concepts for such organometallic drugs, however, are still in their infancy; mainly because an understanding of structure-activity relationships (SARs) has not yet reached a level that allows the extrapolation of general rules. Two main questions result from this observation: Firstly, how muc ...
... Design concepts for such organometallic drugs, however, are still in their infancy; mainly because an understanding of structure-activity relationships (SARs) has not yet reached a level that allows the extrapolation of general rules. Two main questions result from this observation: Firstly, how muc ...
Splice-switching efficiency and specificity for oligonucleotides with
... boundaries during pre-mRNA splicing [1]. Manipulation of premRNA splicing is one approach to finding novel therapies for inherited diseases such as cystic fibrosis [2], β-thalassaemia [3] and Duchenne’s muscular dystrophy [4]. An application that has gained increasing attention since its initial dis ...
... boundaries during pre-mRNA splicing [1]. Manipulation of premRNA splicing is one approach to finding novel therapies for inherited diseases such as cystic fibrosis [2], β-thalassaemia [3] and Duchenne’s muscular dystrophy [4]. An application that has gained increasing attention since its initial dis ...
ABSTRACT Title of Thesis: EXPLORING THE ROLE OF NFκB
... I would like to extend thanks to my advisor, Louisa Wu, for her support and guidance during the last few years. I would also like to thank the members of my committee, Dr. Lian Yong Gao and Dr. Leslie Pick, for their advice on my research and writing. The members (past and present) of the Wu lab hav ...
... I would like to extend thanks to my advisor, Louisa Wu, for her support and guidance during the last few years. I would also like to thank the members of my committee, Dr. Lian Yong Gao and Dr. Leslie Pick, for their advice on my research and writing. The members (past and present) of the Wu lab hav ...
PDF
... During development, the normal differentiation of complex organs involves interactions between the tissues of these organs. Isolation and growth of tissues in vitro and tissue recombination experiments have demonstrated that the extent to which the tissues of an organ are dependent upon reciprocal i ...
... During development, the normal differentiation of complex organs involves interactions between the tissues of these organs. Isolation and growth of tissues in vitro and tissue recombination experiments have demonstrated that the extent to which the tissues of an organ are dependent upon reciprocal i ...
Cenp-A Presence in Drosophila - Institute of Molecular Life Sciences
... Here we show that Cid survives the radical nucleosome replacement process that accompanies spermatogenesis. Centromeric Cid in sperm also perdures during formation of the male pronucleus after fertilization. Finally, analyses after experimental changes of centromeric Cid levels in sperm demonstrate ...
... Here we show that Cid survives the radical nucleosome replacement process that accompanies spermatogenesis. Centromeric Cid in sperm also perdures during formation of the male pronucleus after fertilization. Finally, analyses after experimental changes of centromeric Cid levels in sperm demonstrate ...
Further analysis on lidocaine-induced increase in intracellular Zn2+
... Lidocaine augmented FluoZin-3 fluorescence of rat thymocytes, suggesting the increase in intracellular Zn2+ concentration. However, the mechanism for lidocaine-induced increase in the intensity of FluoZin-3 fluorescence was not elucidated. In this study, in order to reveal the mechanism, the effects ...
... Lidocaine augmented FluoZin-3 fluorescence of rat thymocytes, suggesting the increase in intracellular Zn2+ concentration. However, the mechanism for lidocaine-induced increase in the intensity of FluoZin-3 fluorescence was not elucidated. In this study, in order to reveal the mechanism, the effects ...
Nitric oxide is essential for vesicle formation and
... Several works have demonstrated the involvement of NO in root development. It was shown that NO mediates the auxin response and cell wall biosynthesis in lateral root formation (Correa-Aragunde et al., 2004, 2008). NO also induces adventitious root development (Pagnussat et al., 2004) and modulates ...
... Several works have demonstrated the involvement of NO in root development. It was shown that NO mediates the auxin response and cell wall biosynthesis in lateral root formation (Correa-Aragunde et al., 2004, 2008). NO also induces adventitious root development (Pagnussat et al., 2004) and modulates ...
TGF-beta SIGNAL TRANSDUCTION - University of Colorado-MCDB
... ligand cross-linking studies (19) and genetically implicated in TGF-β signal transduction (20). The cloning of ActR-II also revealed a striking similarity between this molecule and Daf-1, a previously identified orphan receptor from Caenorhabditis elegans (21). These findings provided the basis and ...
... ligand cross-linking studies (19) and genetically implicated in TGF-β signal transduction (20). The cloning of ActR-II also revealed a striking similarity between this molecule and Daf-1, a previously identified orphan receptor from Caenorhabditis elegans (21). These findings provided the basis and ...