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TESIS DOCTORAL
TESIS DOCTORAL

... SUMMARY ................................................................................................................................ XI ...
PDF - International Journal of Biological Sciences
PDF - International Journal of Biological Sciences

... trans-epithelial migration. Nano-mechanical studies of human neutrophils on localized nano-domains could provide the essential information for understanding their immune responsive functions. Using the Atomic Force Microscopy (AFM) – based micro-rheology, we have investigated rheological properties ...
RNA Processing Bodies, Peroxisomes, Golgi Bodies, Mitochondria
RNA Processing Bodies, Peroxisomes, Golgi Bodies, Mitochondria

... Organelle motility, essential for cellular function, is driven by the cytoskeleton. In plants, actin filaments sustain the long-distance transport of many types of organelles, and microtubules typically fine-tune the motile behavior. In shoot epidermal cells of Arabidopsis thaliana seedlings, we sho ...
J V , Feb. 1998, p. 1210–1218
J V , Feb. 1998, p. 1210–1218

... while nondependent mutants form plaques with approximately equal levels of efficiency in the presence and absence of drug. Drug-dependent mutants are particularly useful tools for dissecting the picornavirus infection mechanism because the cap- ...
Hormonal regulation of stem cell maintenance in roots
Hormonal regulation of stem cell maintenance in roots

... research on plant stem cells has focused on how cell division is regulated to form specific microscopy. Cd treatment induced a DNA hypermethylation, as well as an up-regulation of CMT, indicating that de plant organs and tissues, how differentiation is controlled, and of how is coordinated. In this ...
Multicellular trichomes in Arabidopsis - Development
Multicellular trichomes in Arabidopsis - Development

... and co-workers (Hemerly et al., 1995) introduced a dominantnegative mutant of a mitotic cyclin-dependent kinase gene into transgenic tobacco plants, which resulted in plants with essentially normal morphology, but fewer and larger cells. In another study, overexpression of a mitotic B-cyclin in Arab ...
Chapter ONE - VU Research Portal
Chapter ONE - VU Research Portal

... subsequently drive the transition into mitosis during G2 phase of the cell cycle. In contrast to Cdk2, genetic ablation of cyclin A2, the A-type cyclin that is expressed in somatic cells, results in early embryonic lethality (Berthet et al., 2003; Murphy et al., 1997; Ortega et al., 2003; Tetsu and ...
Glycosyltransferase activity of Fringe modulates
Glycosyltransferase activity of Fringe modulates

... Ligands that are capable of activating Notch family receptors are broadly expressed in animal development, but their activity is tightly regulated to allow formation of tissue boundaries1. Members of the fringe gene family have been implicated in limiting Notch activation during boundary formation2– ...
ASYMMETRIC CELL DIVISION IN PLANTS
ASYMMETRIC CELL DIVISION IN PLANTS

... What is the mechanism for partitioning Prospero and Numb to the appropriate daughter cell? During asymmetric divisions in CNS and PNS, which occur in apical-basal orientation, Numb and Prospero colocalize and form a crescent at the basal cell cortex, suggesting a common mechanism for their partition ...
The Pathogenic Fungus Paracoccidioides brasiliensis Exports
The Pathogenic Fungus Paracoccidioides brasiliensis Exports

... Exosome-like vesicles containing virulence factors, enzymes, and antigens have recently been characterized in fungal pathogens, such as Cryptococcus neoformans and Histoplasma capsulatum. Here, we describe extracellular vesicles carrying highly immunogenic ␣-linked galactopyranosyl (␣-Gal) epitopes ...
Jordan Ciccone 9th Grade Pittsburgh Central Catholic Highschool
Jordan Ciccone 9th Grade Pittsburgh Central Catholic Highschool

... -Pseudomonas -Staphylococcus (aureus and epidermidis) ...
Barbiturates Directly Inhibit the Calmodulin/Calcineurin Complex: a
Barbiturates Directly Inhibit the Calmodulin/Calcineurin Complex: a

... the high mortality rate in these patients (Eberhardt et al., ...
Origin and evolution of endoderm and mesoderm
Origin and evolution of endoderm and mesoderm

... understand gastrulation and its molecular regulation. In the first part of this review, we will therefore summarize different modes of gastrulation, that have been evolved in the different phyla. In the ...
10 - Frontiers
10 - Frontiers

... if present) found only in craniates. The ear is topographically closely associated with the facial nerve and FBMs may be among the oldest branchial motor neurons shared among chordates (Fritzsch and Northcutt, 1993; Dufour et al., 2006). IEEs evolved only with the formation of the craniate ear (Frit ...
4 | the tissue level of organization
4 | the tissue level of organization

... The zygote, or fertilized egg, is a single cell formed by the fusion of an egg and sperm. After fertilization the zygote gives rise to rapid mitotic cycles, generating many cells to form the embryo. The first embryonic cells generated have the ability to differentiate into any type of cell in the bo ...
Cells To Tolerate Higher Expression of Bim T+ Bcl
Cells To Tolerate Higher Expression of Bim T+ Bcl

... infection. Pharmacological inhibition of Bcl-2 resulted in a significant reduction in the numbers of gp33-sp KLRG1lowCD127high cells, as 90% of these cells were lost during the contraction phase compared with an ∼45% reduction in vehicle-treated mice (Fig. 2B). In contrast, loss of KLRG1highCD127low ...
Host cell-derived lactate functions as an effector molecule in
Host cell-derived lactate functions as an effector molecule in

... infected and uninfected FaDu cells. The conditioned medium (CM) from the infected or uninfected cells was added at a 1:1 volume ratio to bacterial suspensions in which microcolonies had been allowed to form for 3 h (Fig 2A). Regardless of whether the CM was from the infected or uninfected cells, a s ...
Bacterial tail anchors can target to the mitochondrial outer
Bacterial tail anchors can target to the mitochondrial outer

... membrane during stationary phase [19], a role in line with promotion of co-translational ...
Exosomes with major histocompatibility complex class II and
Exosomes with major histocompatibility complex class II and

... CD82 [7], which interact with membrane proteins, such as integrins and human leukocyte antigen (HLA)-DR [10]. Exosomes may not only have a role in T-cell activation, but may also function as a communicator between cells in the immune system. Intestinal epithelial cells secrete exosome-like vesicles, ...
Scanned by CamScanner
Scanned by CamScanner

... embryo during its earliest stages of development. The weak barriers against ethanol during the earliest stages of development means that newly fertilized embryos that are undergoing critical early developmental processes such as zygotic genome activation (ZGA) are very susceptible. This event occurs ...
RNA Processing Bodies, Peroxisomes, Golgi
RNA Processing Bodies, Peroxisomes, Golgi

... Organelle motility, essential for cellular function, is driven by the cytoskeleton. In plants, actin filaments sustain the long-distance transport of many types of organelles, and microtubules typically fine-tune the motile behavior. In shoot epidermal cells of Arabidopsis thaliana seedlings, we sho ...
Role of the Sodium-Dependent Phosphate Cotransporters and
Role of the Sodium-Dependent Phosphate Cotransporters and

... manner for the first 30–60 min and then slowed down but without reaching equilibrium even after 5 h (Fig. 2A). As we also observed that uranium uptake was significantly reduced when these experiments were performed at 4C, we can conclude that the mechanism through which uranium is taken up by LLC-P ...
Dubrulle and Pourquie, 2004 - Development
Dubrulle and Pourquie, 2004 - Development

... same AP level for a given pair of somites. Finally, somite boundary formation is not only periodical but also synchronous, each somite of a pair being formed simultaneously, indicating that the development between the left and right side is tightly coordinated. These latter properties imply that the ...
A proteomic chronology of gene expression through the cell cycle in
A proteomic chronology of gene expression through the cell cycle in

... proportion of cells in each cell cycle phase was calculated by fitting the data to the Watson model (Watson et al., 1987). Fractions F1 and F2 were enriched in G1 cells, F3 and four were enriched in S phase cells and F5 and F6 were enriched in G2 and M phase cells (G2&M). Second, we used immunoblott ...
BMP and Delta/Notch signaling control the development of
BMP and Delta/Notch signaling control the development of

... undergo metamorphosis and lose many chordate characteristics as they become sessile adults. Therefore, it was traditionally thought that amphioxus is the sister group of the vertebrates and that tunicates compose the basal chordate group; however, recent phylogenomic analyses have reverted their pos ...
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Amitosis

Amitosis (a- + mitosis) is absence of mitosis, the usual form of cell division in the cells of eukaryotes. There are several senses in which eukaryotic cells can be amitotic. One refers to capability for non-mitotic division and the other refers to lack of capability for division. In one sense of the word, which is now mostly obsolete, amitosis is cell division in eukaryotic cells that happens without the usual features of mitosis as seen on microscopy, namely, without nuclear envelope breakdown and without formation of mitotic spindle and condensed chromosomes as far as microscopy can detect. However, most examples of cell division formerly thought to belong to this supposedly ""non-mitotic"" class, such as the division of unicellular eukaryotes, are today recognized as belonging to a class of mitosis called closed mitosis. A spectrum of mitotic activity can be categorized as open, semi-closed, and closed mitosis, depending on the fate of the nuclear envelope. An exception is the division of ciliate macronucleus, which is not mitotic, and the reference to this process as amitosis may be the only legitimate use of the ""non-mitotic division"" sense of the term today. In animals and plants which normally have open mitosis, the microscopic picture described in the 19th century as amitosis most likely corresponded to apoptosis, a process of programmed cell death associated with fragmentation of the nucleus and cytoplasm. Relatedly, even in the late 19th century cytologists mentioned that in larger life forms, amitosis is a ""forerunner of degeneration"".Another sense of amitotic refers to cells of certain tissues that are usually no longer capable of mitosis once the organism has matured into adulthood. In humans this is true of various muscle and nerve tissue types; if the existing ones are damaged, they cannot be replaced with new ones of equal capability. For example, cardiac muscle destroyed by heart attack and nerves destroyed by piercing trauma usually cannot regenerate. In contrast, skin cells are capable of mitosis throughout adulthood; old skin cells that die and slough off are replaced with new ones. Human liver tissue also has a sort of dormant regenerative ability; it is usually not needed or expressed but can be elicited if needed.
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