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Rabbit Genetics - Heavenly Hares Rabbitry
Rabbit Genetics - Heavenly Hares Rabbitry

... Rabbit Genetics For Broken, Solid, And Charlie Patterns There are several genes involved in determining the color and pattern of a rabbit's fur. The topic of rabbit color genetics is sufficiently complicated to warrant whole books on the subject. This page will consider only the En/en gene, which de ...
Linköping University Post Print Segment-specific Neuronal Sub-type Specification by the Integration of
Linköping University Post Print Segment-specific Neuronal Sub-type Specification by the Integration of

Chapter 1 - Institut Montefiore
Chapter 1 - Institut Montefiore

... • Because there are only 20 amino acids that need to be coded, the genetic code can be said to be degenerate, with the third position often being redundant • Depending on the starting point of reading, there are three possible variants to translate a given base sequence into an amino acid sequence • ...
UNIT TWO - BIOLOGICAL EXPLANATIONS OF AGGRESSION File
UNIT TWO - BIOLOGICAL EXPLANATIONS OF AGGRESSION File

... influence both the structural and functional aspects of an animal’s biology. Lagerspetz (1981) does make the point however, that genetic factors do not absolutely determine aggressive behaviour, but that environmental factors are also very important. For example, she points out that both strains of ...
- Iranian Journal of Basic Medical Sciences
- Iranian Journal of Basic Medical Sciences

... strains, have caused a major health problem in global community (18). Rapid detection of MDR strains would help efficient treatment of patients and prevents widespread distribution of these isolates (1-5). This study aimed to survey the use of PCR-RFLP in comparison with proportional method for rapi ...
Estrogen receptor β gene polymorphisms and susceptibility to
Estrogen receptor β gene polymorphisms and susceptibility to

... leiomyomas when compared with autologous myometrial tissue [7–11]. In 1996, the second estrogen receptor, ERb, was identified which is coded by the ESR2 gene. Like ERa, ERb also was reported to be expressed at higher levels in leiomyomas when compared with matched myometrium [12]. There are studies ...
Consistent risk group-associated differences in human
Consistent risk group-associated differences in human

... infected people in the Amsterdam Cohorts of homosexuals and intravenous drug users has revealed that the virus variants that were found in the homosexual men and haemophiliacs could be distinguished by two mutations from variants found in drug users (Kuiken et al., 1993). These mutations were both s ...
Running title Variation in Barley Brassinosteroid
Running title Variation in Barley Brassinosteroid

... Hv-BRD, encoding a brassinosteroid-6-oxidase, is located in the telomeric region of the short arm of barley chromosome 2H (Figure 5, Supplemental Figure 5A online). The location of HvBRD is within the mutant donor introgressions of the near-isogenic lines ari-u.245, brh3.g, brh3.h, brh3.y, and ert-t ...
1. (a) (i) A gene controlling coat colour in cats is sex linked. The two
1. (a) (i) A gene controlling coat colour in cats is sex linked. The two

... in seahorses is known as disruptive selection. This is where the extreme phenotypes are more likely to survive and reproduce than the intermediate phenotypes. (b) ...
mgm1, the earliest sex-specific germline marker in Drosophila
mgm1, the earliest sex-specific germline marker in Drosophila

... germ cells are essentially inert at this stage. Interestingly, gonads of masculinized XX animals lacking the feminizing transformer (tra) function, are indistinguishable from male gonads in first instar larvae both in size and in appearance of the germ cells (Seidel, 1963; Steinmann-Zwicky, 1994a). ...
Obesity — a genetic disease of adipose tissue?
Obesity — a genetic disease of adipose tissue?

... pro-opiomelanocortin (Krude et al. 1998), prohormone convertase-1 (Jackson et al. 1997) and melanocortin-4 receptor (Vaisse et al. 1998; Yeo et al. 1999) have been described, all of which associate with juvenile-onset morbid obesity. The mechanisms responsible for excess fat accumulation in the rare ...
Fluorescence in Situ Hybridization Evaluation of c-erbB
Fluorescence in Situ Hybridization Evaluation of c-erbB

... stepwise progression of solid tumors. Moreover, oncogene amplification may be associated with aggressive growth and may be a useful indicator of progression and prognosis in various human cancers (1). A few studies using FISH showed c-erbB-2 gene amplification in bladder cancers, and the clinical si ...
Evaluation of the Water Stress-Inducible
Evaluation of the Water Stress-Inducible

... being a constant source of support throughout this program. I am grateful to Ray Zabulionis, who made my experience as a teaching assistant an enjoyable one. His example is one that I will strive to follow in any teaching or leadership role. A special thank you also to Alex Molnar for assistance wit ...
Transgenerational epigenetics in the germline cycle
Transgenerational epigenetics in the germline cycle

... total generative capacity at each generation, is considered a totipotent lineage. In somatic tissues, terminal differentiation is accompanied by substantial epigenetic programming that cements commitment to specific phenotypes, thus differentiation is usually associated with loss of pluripotency. Ga ...
Genetics Part I
Genetics Part I

... How is it possible that genes from two parents unite to form a new life that still has the critically correct number of chromosomes? To understand the transfer of traits from parents to offspring, a clear concept of the nature of DNA, chromosomes, and genes is vital. We will begin by looking at a sp ...
Chapter 10: DIPLOIDY
Chapter 10: DIPLOIDY

... cell at fertilization. Haploid cells have half the number of chromosomes (n) as diploid - i.e. a haploid cell contains only one complete set of chromosomes. Haploid cells are found in various algae, various male bees, wasps and ants. Haploid cells should not be confused with monoploid cells as the m ...
CommercialOutbreds07..
CommercialOutbreds07..

... mosaic of the founders using a hidden Markov model {Mott, 2000 #5686}. We used the Perlegen NIEHS genotypes {Frazer, 2007 #7202} as a reference set of 15 inbred founders and analysed all stocks at the four loci (figure 4a) and performed genome-wide analyses in a subset of colonies (figure 4b). While ...
12q14 microdeletions
12q14 microdeletions

... the microdeletion is present or not and which genes are deleted (size of the deletion). It is believed that the effects are caused by the presence of only one copy of these genes instead of two, as expected normally. The 12q14 region is denoted by the red bar on the diagram ...
Host-range expansion of Spodoptera exigua multiple
Host-range expansion of Spodoptera exigua multiple

... transported to the nucleus in a cytoskeleton-dependent manner and enter the nucleus through nuclear pores (Ohkawa et al., 2002), after which transcription and replication can occur. Host-range data are often lacking when a novel virus species is described. In general, baculoviruses are said to have ...
Formal Outline Introduction The Founding of PTC When Who How
Formal Outline Introduction The Founding of PTC When Who How

... Phenylthiocarbamide, also known as phenylthiourea, and more commonly PTC, is an organic compound that allows the holder of a specific gene to taste the compound as bitter, slightly bitter, or completely tasteless. Respectively, these people are known as “tasters” and “nontasters.” Approximately 75% ...
Why Compare sequences?
Why Compare sequences?

... Why do people suggest that translated sequences be used to search for relatives in databanks? link Protein sequences are composed of a 20 aa alphabet determined by 61 degenerate codons. When the DNA sequences are translated into 21 different types of codons (20 aa and a terminator), the information ...
Determination of IL-23 receptor gene polymorphism in Iranian
Determination of IL-23 receptor gene polymorphism in Iranian

... role of other genetic/environmental factors in the susceptibility and pathogenesis of the disease [26-28]. In Iranian population, about 70% of AS patients are HLA-B27 positive; therefore, the prevalence of HLA-B27 is lower than other parts of the world [29]. However, in the Iranian population, the e ...
Breeding Policy for the RagaMuffin Cat
Breeding Policy for the RagaMuffin Cat

... Non-Agouti (a) ...
187-192. Control of transcription by Pontin and Reptin
187-192. Control of transcription by Pontin and Reptin

... the observation that mixed preparations of Pontin and Reptin display a solid ATPase activity, whereas either protein alone (either as a mono- or oligomer) is almost inactive (4, 13-15; but see 16). In this context it is also worth noting that Pontin and Reptin have non-redundant functions in all sys ...
14_DetailLectOut
14_DetailLectOut

... When sperm with four classes of alleles and ova with four classes of alleles combine, there are 16 equally probable ways in which the alleles can combine in the F2 generation. ...
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Site-specific recombinase technology



Nearly every human gene has a counterpart in the mouse (regardless of the fact that a minor set of orthologues had to follow species specific selection routes). This made the mouse the major model for elucidating the ways in which our genetic material encodes information. In the late 1980s gene targeting in murine embryonic stem (ES-)cells enabled the transmission of mutations into the mouse germ line and emerged as a novel option to study the genetic basis of regulatory networks as they exist in the genome. Still, classical gene targeting proved to be limited in several ways as gene functions became irreversibly destroyed by the marker gene that had to be introduced for selecting recombinant ES cells. These early steps led to animals in which the mutation was present in all cells of the body from the beginning leading to complex phenotypes and/or early lethality. There was a clear need for methods to restrict these mutations to specific points in development and specific cell types. This dream became reality when groups in the USA were able to introduce bacteriophage and yeast-derived site-specific recombination (SSR-) systems into mammalian cells as well as into the mouse
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