Wk12-DeanApop
... Further research? Other factors may be involved in HBx/FasL • Nuclear factors of activated T-cells (NFAT): evidence for FasL regulatory role • Interferon response factor (IGF): binds FasL promoter • Nur77: regulates FasL expression in presence of HBx (even though it doesn’t seem to interact with Fa ...
... Further research? Other factors may be involved in HBx/FasL • Nuclear factors of activated T-cells (NFAT): evidence for FasL regulatory role • Interferon response factor (IGF): binds FasL promoter • Nur77: regulates FasL expression in presence of HBx (even though it doesn’t seem to interact with Fa ...
PowerPoint - 埼玉医科大学総合医療センター 内分泌・糖尿病内科
... INSERM Unité 1016, Centre National de la Recherche Scientifique Unité Mixte de Recherche 8104, Institut Cochin (G.A., R.L., S.E., M.R.-R., A.G., W.L., O.B., L.L., S.R., K.P., F.R.-C., F.L., L. Groussin, X.B., B.R., J.B.), Faculté de Médecine Paris Descartes, Université Paris Descartes, Sorbonne Par ...
... INSERM Unité 1016, Centre National de la Recherche Scientifique Unité Mixte de Recherche 8104, Institut Cochin (G.A., R.L., S.E., M.R.-R., A.G., W.L., O.B., L.L., S.R., K.P., F.R.-C., F.L., L. Groussin, X.B., B.R., J.B.), Faculté de Médecine Paris Descartes, Université Paris Descartes, Sorbonne Par ...
Parallel Genetic and Phenotypic Evolution of DNA Superhelicity in
... Several other phenotypic traits evolved in parallel in most or all populations, including cell size (Lenski et al. 1998; Philippe et al. 2009), growth parameters (Vasi et al. 1994), catabolic functions (Cooper and Lenski 2000; Pelosi et al. 2006), and global gene expression profiles. Genetic studies ...
... Several other phenotypic traits evolved in parallel in most or all populations, including cell size (Lenski et al. 1998; Philippe et al. 2009), growth parameters (Vasi et al. 1994), catabolic functions (Cooper and Lenski 2000; Pelosi et al. 2006), and global gene expression profiles. Genetic studies ...
Genetic algorithms with multi-parent recombination
... scanning and diagonal crossover that generalize uniform, respecively n-point crossovers. In this paper we concentrate on the gene scanning mechanism and we perform extensive tests to observe the effect of different numbers of parents on the performance of the GA. We consider different problem types, ...
... scanning and diagonal crossover that generalize uniform, respecively n-point crossovers. In this paper we concentrate on the gene scanning mechanism and we perform extensive tests to observe the effect of different numbers of parents on the performance of the GA. We consider different problem types, ...
Jolly Good Knowledge from the Seven Seas Monday,October 9
... 1. What did Mendel experiment with to learn about genetics? Pea plants 2. A scientist who studies heredity is a geneticist. 3. Where do organisms inherit genes from?the parents 4. What are physical characteristics of an organism that are passed down from one generation to the next called? traits ...
... 1. What did Mendel experiment with to learn about genetics? Pea plants 2. A scientist who studies heredity is a geneticist. 3. Where do organisms inherit genes from?the parents 4. What are physical characteristics of an organism that are passed down from one generation to the next called? traits ...
Blankety Blank - misslongscience
... Blankety Blank 2. A gene is a sequence of nucleotides along a piece of DNA that determines a single characteristic of an organism. It does this by coding for particular polypeptides that make up the enzymes needed in a biochemical pathway. ...
... Blankety Blank 2. A gene is a sequence of nucleotides along a piece of DNA that determines a single characteristic of an organism. It does this by coding for particular polypeptides that make up the enzymes needed in a biochemical pathway. ...
January 1997 Biology 30 Grade 12 Diploma Examination
... Gel electrophoresis is a technique used to separate DNA or protein fragments. A sample of DNA is fragmented by enzymes, and then the sample is placed in a gel. An electric current is passed through the gel. Because the DNA is electrically charged, the DNA fragments migrate. The following gel plate, ...
... Gel electrophoresis is a technique used to separate DNA or protein fragments. A sample of DNA is fragmented by enzymes, and then the sample is placed in a gel. An electric current is passed through the gel. Because the DNA is electrically charged, the DNA fragments migrate. The following gel plate, ...
Full Text - Archives of Pediatric Infectious Diseases
... penem-EDTA disc inhibition zone is more than 4 mm and the inhibition zone is not seen for Imipenem disc, strain is considered as metallo-β-lactamase positive (such as NDM-1). The Hodge-test has low specificity, therefore, it is not recommended for metallo-β-lactamase identification (20). Carbapenema ...
... penem-EDTA disc inhibition zone is more than 4 mm and the inhibition zone is not seen for Imipenem disc, strain is considered as metallo-β-lactamase positive (such as NDM-1). The Hodge-test has low specificity, therefore, it is not recommended for metallo-β-lactamase identification (20). Carbapenema ...
Formation of synovial joints and articular cartilage
... Thus, during limb development, the expression of CD44 in the interzone and at the developing articular surfaces, and the increased HA synthesis associated with cavitation can facilitate tissue separation and create a functional joint cavity [3, 14, 49]. In animals deficient in HA synthase-2, the for ...
... Thus, during limb development, the expression of CD44 in the interzone and at the developing articular surfaces, and the increased HA synthesis associated with cavitation can facilitate tissue separation and create a functional joint cavity [3, 14, 49]. In animals deficient in HA synthase-2, the for ...
Developing expressed sequence tag libraries and
... and to increase the number of DNA sequences available for the Rosaceae research community and raspberry breeders. EST-SSRs reported here can significantly advance comparative linkage analysis among Rubus species. ...
... and to increase the number of DNA sequences available for the Rosaceae research community and raspberry breeders. EST-SSRs reported here can significantly advance comparative linkage analysis among Rubus species. ...
Genetic Basis of Polymurphism in the Color Vision of
... values of 543, 556 and 562mrt), in each case there is evidence for a photopi~ent pol~o~hism similar in character to that described for the squirrel monkey, i.e. each species appears to have the three classes of middle to long wavelength cone pigments with individual animals having any one or any pai ...
... values of 543, 556 and 562mrt), in each case there is evidence for a photopi~ent pol~o~hism similar in character to that described for the squirrel monkey, i.e. each species appears to have the three classes of middle to long wavelength cone pigments with individual animals having any one or any pai ...
Causes of Non-Mendelian phenotypes
... trinucleotide repeats that lie within the affected gene. The number of repeats increases in each successive generation. Expansion of the DNA repeats (probably by slipped mispairing) has been shown to cause anticipation in Fragile X syndrome, myotonic dystrophy, spinocerebellar ataxia (but not in spi ...
... trinucleotide repeats that lie within the affected gene. The number of repeats increases in each successive generation. Expansion of the DNA repeats (probably by slipped mispairing) has been shown to cause anticipation in Fragile X syndrome, myotonic dystrophy, spinocerebellar ataxia (but not in spi ...
The relationship between higher‑order chromatin structure and
... fibre, largely because this is the only level of higher‑order chromatin structure that we have reasonable models for. However, it is clear from electron microscopy studies that a lot of mammalian chromatin is packaged into levels beyond this. The few assays that we have for tertiary levels of chroma ...
... fibre, largely because this is the only level of higher‑order chromatin structure that we have reasonable models for. However, it is clear from electron microscopy studies that a lot of mammalian chromatin is packaged into levels beyond this. The few assays that we have for tertiary levels of chroma ...
Candidate gene resequencing to identify rare, pedigree
... Copyright and moral rights for the publications made accessible in the public portal are retained by the authors and/or other copyright owners and it is a condition of accessing publications that users recognise and abide by the legal requirements associated with these rights. • Users may download a ...
... Copyright and moral rights for the publications made accessible in the public portal are retained by the authors and/or other copyright owners and it is a condition of accessing publications that users recognise and abide by the legal requirements associated with these rights. • Users may download a ...
Article Old but Not (So) Degenerated—Slow
... chromosomes, it has been estimated that avian sex chromosome differentiation was initiated at least 130 Ma. Data from chicken suggest that Z-W recombination ceased in a stepwise fashion, probably at least three or four times (Lawson Handley et al. 2004; Nam and Ellegren 2008; Wright et al. 2012), fo ...
... chromosomes, it has been estimated that avian sex chromosome differentiation was initiated at least 130 Ma. Data from chicken suggest that Z-W recombination ceased in a stepwise fashion, probably at least three or four times (Lawson Handley et al. 2004; Nam and Ellegren 2008; Wright et al. 2012), fo ...
Early assessment of ambiguous genitalia
... ‘‘indifferent’’ gonads form on the genital ridges. The development of the fetal adrenals and gonads occur in parallel, as before migration, the potential steroidogenic cells of both originate from the mesonephros. There are many genes and transcription factors that are expressed in both tissues (for ...
... ‘‘indifferent’’ gonads form on the genital ridges. The development of the fetal adrenals and gonads occur in parallel, as before migration, the potential steroidogenic cells of both originate from the mesonephros. There are many genes and transcription factors that are expressed in both tissues (for ...
Predicting tRNA and tmRNA genes Aragorn - SEA
... literature.) It is highly unusual that a phage with multiple tRNAs will contain a sole tRNA distant genomically from all the others within its genome found by the programs, or encoded on the opposite strand as all the others, or encoded within a ORF called by GeneMark or Glimmer that has high coding ...
... literature.) It is highly unusual that a phage with multiple tRNAs will contain a sole tRNA distant genomically from all the others within its genome found by the programs, or encoded on the opposite strand as all the others, or encoded within a ORF called by GeneMark or Glimmer that has high coding ...
Brooker Chapter 4
... A measure of how variation in expression of a given allele occurs incomplete penetrance describes the lack of effect a deleterious allele might have in an individual carrying it ...
... A measure of how variation in expression of a given allele occurs incomplete penetrance describes the lack of effect a deleterious allele might have in an individual carrying it ...
Predicting_tRNA_and_tmRNA_genes_12-2-16
... literature.) It is highly unusual that a phage with multiple tRNAs will contain a sole tRNA distant genomically from all the others within its genome found by the programs, or encoded on the opposite strand as all the others, or encoded within a ORF called by GeneMark or Glimmer that has high coding ...
... literature.) It is highly unusual that a phage with multiple tRNAs will contain a sole tRNA distant genomically from all the others within its genome found by the programs, or encoded on the opposite strand as all the others, or encoded within a ORF called by GeneMark or Glimmer that has high coding ...
Bethesda Guidelines and MSI Testing
... What Is MSI?* Nearly all LS tumors differ from their sporadic counterparts and most are characterized by MSI. MSI mutations occur at short repetitive sequences called microsatellites. Most are insertion or deletion mutations and, as a consequence of loss of DNA MMR activity. ...
... What Is MSI?* Nearly all LS tumors differ from their sporadic counterparts and most are characterized by MSI. MSI mutations occur at short repetitive sequences called microsatellites. Most are insertion or deletion mutations and, as a consequence of loss of DNA MMR activity. ...
PDF Links - Asian-Australasian Journal of Animal Sciences
... variation in the exonic region of a gene may lead to changes in amino acids which alter the expressed protein. Moreover, although intronic variation cannot change the amino acid sequence of the protein, it may play a significant role in gene splicing or binding of regulatory proteins during transcri ...
... variation in the exonic region of a gene may lead to changes in amino acids which alter the expressed protein. Moreover, although intronic variation cannot change the amino acid sequence of the protein, it may play a significant role in gene splicing or binding of regulatory proteins during transcri ...
Presence of a mitochondrial-type 70
... mainly on ribosomal RNA, show that three amitochondriate protist lineages, diplomonads, microsporidia, and trichomonads, emerge consistently at the base of the eukaryotic tree before groups having mitochondria. This suggests that these groups could have diverged before the mitochondrial endosymbiosi ...
... mainly on ribosomal RNA, show that three amitochondriate protist lineages, diplomonads, microsporidia, and trichomonads, emerge consistently at the base of the eukaryotic tree before groups having mitochondria. This suggests that these groups could have diverged before the mitochondrial endosymbiosi ...
Force spectroscopy of single DNA and RNA molecules Mark C
... molecules. In these experiments, one end of the molecule is held at a fixed position, while the other end of the molecule is extended at constant force or to a fixed position. These techniques include atomic force microscopy (AFM) [1], optical tweezers [2] and magnetic tweezers [3,4•], as shown in F ...
... molecules. In these experiments, one end of the molecule is held at a fixed position, while the other end of the molecule is extended at constant force or to a fixed position. These techniques include atomic force microscopy (AFM) [1], optical tweezers [2] and magnetic tweezers [3,4•], as shown in F ...
PSEUDOCHOLINESTERASE ACTIVITY: DETERMINATION AND INTERPRETATION IN PEDIATRIC ANESTHESIA A
... adult and which persists until the third year5,6. The later workers4 report that the activity remains at about 50% of the adult value until 6 months and no particular interest seems to have been paid to the next 2.5 years of life. In fact, there are no established norms until the age of 3 years7. Be ...
... adult and which persists until the third year5,6. The later workers4 report that the activity remains at about 50% of the adult value until 6 months and no particular interest seems to have been paid to the next 2.5 years of life. In fact, there are no established norms until the age of 3 years7. Be ...
Site-specific recombinase technology
Nearly every human gene has a counterpart in the mouse (regardless of the fact that a minor set of orthologues had to follow species specific selection routes). This made the mouse the major model for elucidating the ways in which our genetic material encodes information. In the late 1980s gene targeting in murine embryonic stem (ES-)cells enabled the transmission of mutations into the mouse germ line and emerged as a novel option to study the genetic basis of regulatory networks as they exist in the genome. Still, classical gene targeting proved to be limited in several ways as gene functions became irreversibly destroyed by the marker gene that had to be introduced for selecting recombinant ES cells. These early steps led to animals in which the mutation was present in all cells of the body from the beginning leading to complex phenotypes and/or early lethality. There was a clear need for methods to restrict these mutations to specific points in development and specific cell types. This dream became reality when groups in the USA were able to introduce bacteriophage and yeast-derived site-specific recombination (SSR-) systems into mammalian cells as well as into the mouse