Drosophila Muller F Elements Maintain a Distinct Set of Genomic
... analyses only focused on the Muller elements A–E and the properties of the F element generally have not been examined carefully. In this study, we have built on these genomic resources by performing manual sequence improvement and gene annotation of the D. erecta, D. mojavensis, and D. grimshawi F e ...
... analyses only focused on the Muller elements A–E and the properties of the F element generally have not been examined carefully. In this study, we have built on these genomic resources by performing manual sequence improvement and gene annotation of the D. erecta, D. mojavensis, and D. grimshawi F e ...
trans - bioRxiv
... few documented systems exist that permit the comparison of effect linkage, allele-specificity and ...
... few documented systems exist that permit the comparison of effect linkage, allele-specificity and ...
- Philsci-Archive
... My aim in this essay is to elucidate what is meant when causal relationships are described as more or less contingent, specific, or framed at an appropriate or inappropriate level, to explore some of the interrelationships among these notions, and locate them notions within a larger framework for d ...
... My aim in this essay is to elucidate what is meant when causal relationships are described as more or less contingent, specific, or framed at an appropriate or inappropriate level, to explore some of the interrelationships among these notions, and locate them notions within a larger framework for d ...
The Coat of Many Colors
... Again, keep in mind as you continue to read that the merle allele is NOT a color allele. I know we’ve said this before, but it’s worth repeating! We’ll need a few definitions to understand how merle works. For example, we briefly mentioned the meaning of allele earlier. Here’s an expanded definition ...
... Again, keep in mind as you continue to read that the merle allele is NOT a color allele. I know we’ve said this before, but it’s worth repeating! We’ll need a few definitions to understand how merle works. For example, we briefly mentioned the meaning of allele earlier. Here’s an expanded definition ...
Application to Modify an Approved Exempt or Notifiable Low Risk
... As Facility Manager I have been informed of the nature of and risks involved with this GMO dealing and after consideration of them, I hereby consent to the work being performed in the listed facility. I will ensure that the appropriate safety procedures are followed and that personnel are appropriat ...
... As Facility Manager I have been informed of the nature of and risks involved with this GMO dealing and after consideration of them, I hereby consent to the work being performed in the listed facility. I will ensure that the appropriate safety procedures are followed and that personnel are appropriat ...
Genetic Diversity in Apple Fruit Moth Indicate Different Clusters in
... the population dynamics of Hydropsyche orientalis and Stenopsyche marmorata in Japan [27]. The greatest advantage of AFLP is probably that it does not need previous sequence information of the species. Additional arguments for the choice of AFLP, was the difficulties of the development of microsatel ...
... the population dynamics of Hydropsyche orientalis and Stenopsyche marmorata in Japan [27]. The greatest advantage of AFLP is probably that it does not need previous sequence information of the species. Additional arguments for the choice of AFLP, was the difficulties of the development of microsatel ...
The Evolution of Populations
... generation span of about two days. It also has an RNA genome, which has a much higher mutation rate than a typical DNA genome because of the lack of RNA repair mechanisms in host cells (see Chapter 19). For this reason, it is unlikely that a single-drug treatment would ever be effective against HIV; ...
... generation span of about two days. It also has an RNA genome, which has a much higher mutation rate than a typical DNA genome because of the lack of RNA repair mechanisms in host cells (see Chapter 19). For this reason, it is unlikely that a single-drug treatment would ever be effective against HIV; ...
PDF
... accounting for about 95% of known cases (Patterson, 2003). The large Npc1 protein has 13 transmembrane domains and a sterolsensing domain (SSD) (Carstea et al., 1997; Loftus et al., 1997). Npc2, a small, secreted protein that binds cholesterol strongly, was first found as an abundant component of hu ...
... accounting for about 95% of known cases (Patterson, 2003). The large Npc1 protein has 13 transmembrane domains and a sterolsensing domain (SSD) (Carstea et al., 1997; Loftus et al., 1997). Npc2, a small, secreted protein that binds cholesterol strongly, was first found as an abundant component of hu ...
lecture - Berkeley MCB
... “Up until now, it had seemed reasonable to postulate that constitutive mutants synthesized an endogenous inducer which was absent in inducible cells. The results described here suggest an exactly opposite hypothesis. The facts can be explained by the supposition that the i gene determines (via an en ...
... “Up until now, it had seemed reasonable to postulate that constitutive mutants synthesized an endogenous inducer which was absent in inducible cells. The results described here suggest an exactly opposite hypothesis. The facts can be explained by the supposition that the i gene determines (via an en ...
Microarray-based comparative genomic hybridisation (array CGH)
... (where a section of a chromosome is inverted or reversed), will not be identified using array CGH. This is because balanced chromosome rearrangements do not result in any loss or gain of chromosome material. It will also not detect some types of polyploidy (more than the usual 2 sets of chromosomes) ...
... (where a section of a chromosome is inverted or reversed), will not be identified using array CGH. This is because balanced chromosome rearrangements do not result in any loss or gain of chromosome material. It will also not detect some types of polyploidy (more than the usual 2 sets of chromosomes) ...
LAB 1: Scientific Method/Tools of Scientific Inquiry
... Chickens don’t give birth to lizards and apple trees don’t give rise to pine trees. So what is the biological basis for this obvious reality? You probably already know this has to do with genes, genes one inherits from one’s parents. However the process of passing on genes from one generation to the ...
... Chickens don’t give birth to lizards and apple trees don’t give rise to pine trees. So what is the biological basis for this obvious reality? You probably already know this has to do with genes, genes one inherits from one’s parents. However the process of passing on genes from one generation to the ...
RESEARCH NOTES
... If mutations conferring resistance to FPA and to MBC affect the components of spore excision, N. tetrasperma should provide a sensitive system for detecting such mutations. Such mutants could provide information on the part played by cytoskeletal elements during development. The strains used were N. ...
... If mutations conferring resistance to FPA and to MBC affect the components of spore excision, N. tetrasperma should provide a sensitive system for detecting such mutations. Such mutants could provide information on the part played by cytoskeletal elements during development. The strains used were N. ...
Teacher Guide: Gene Expression. By Ann Brokaw.
... include up-to-date research, prompt students to process material, help reinforce textbook material, and stimulate discussions and explorations of current biological topics. For these reasons, I routinely use HHMI’s BioInteractive website and Holiday Lectures on Science DVDs in my classroom to highli ...
... include up-to-date research, prompt students to process material, help reinforce textbook material, and stimulate discussions and explorations of current biological topics. For these reasons, I routinely use HHMI’s BioInteractive website and Holiday Lectures on Science DVDs in my classroom to highli ...
Package `GOFunction`
... This function uses the following principles to treat for glocal redundancy between GO terms which share multiple function genes but have no ancient-offspring relationship. For a pair of overlapping terms, GO-function remains one term only if (1) there is additional evidence that the nonoverlapping g ...
... This function uses the following principles to treat for glocal redundancy between GO terms which share multiple function genes but have no ancient-offspring relationship. For a pair of overlapping terms, GO-function remains one term only if (1) there is additional evidence that the nonoverlapping g ...
PAX6 mRNA Transcript Analysis in Various Ocular/Non
... Partial PAX6 is illegitimately expressed in mutant WBC lymphocytes and not in wild type WBC lymphocytes hence it needs to explore the function of PAX6 mRNA in mutant. These results suggest that the PAX6 gene expression patterns of is highly variable in each ocular/non-ocular tissue types and most li ...
... Partial PAX6 is illegitimately expressed in mutant WBC lymphocytes and not in wild type WBC lymphocytes hence it needs to explore the function of PAX6 mRNA in mutant. These results suggest that the PAX6 gene expression patterns of is highly variable in each ocular/non-ocular tissue types and most li ...
Cloning and expression analysis of follicle
... composed of a common a subunit. The a subunit links non-covalently to a hormone-specific b-subunit that confers the biological activity. These proteins coordinately control gonadal steroidogenesis by binding to their respective receptors (FSHR and LHR) in the gonads. (Gharib et al. 1990) The FSH and ...
... composed of a common a subunit. The a subunit links non-covalently to a hormone-specific b-subunit that confers the biological activity. These proteins coordinately control gonadal steroidogenesis by binding to their respective receptors (FSHR and LHR) in the gonads. (Gharib et al. 1990) The FSH and ...
Molecular Evolution of the Endosperm Starch Synthesis Pathway
... scan of variation can be used as neutral reference for detecting selection. A recent genome-wide survey of variation in O. rufipogon and O. sativa indicated a complex demographic history (Caicedo et al. 2007). In this study, we have used these recently published genome-wide variation data, consistin ...
... scan of variation can be used as neutral reference for detecting selection. A recent genome-wide survey of variation in O. rufipogon and O. sativa indicated a complex demographic history (Caicedo et al. 2007). In this study, we have used these recently published genome-wide variation data, consistin ...
Steve Downes
... variance, VI: alleles at one locus have an effect on the phenotype that is dependent upon alleles at one or more other loci. There may be a contribution to phenotypic variance from gene/environment interaction, VG X E: the effect of the environment on the phenotype differs between genotypes. VP can ...
... variance, VI: alleles at one locus have an effect on the phenotype that is dependent upon alleles at one or more other loci. There may be a contribution to phenotypic variance from gene/environment interaction, VG X E: the effect of the environment on the phenotype differs between genotypes. VP can ...
Purified Native dsDNA, Calf Thymus, ELISA/Antigen grade
... appear to play a central role in the pathogenesis of tissue injury and are closely correlated with clinical activity. Their presence is also associated with active lupus and usually with immune complex glomerulo-nephritis. Antibodies to ds-DNA are directed against the phosphate-deoxyribose backbone ...
... appear to play a central role in the pathogenesis of tissue injury and are closely correlated with clinical activity. Their presence is also associated with active lupus and usually with immune complex glomerulo-nephritis. Antibodies to ds-DNA are directed against the phosphate-deoxyribose backbone ...
1 Depleting gene activities in early Drosophila embryos
... early activity of Torso signaling and the later function of EGFR signaling. The D-raf example illustrates how different embryonic phenotypes can be observed depending on the level of either maternal or zygotic gene activity present at a specific developmental ...
... early activity of Torso signaling and the later function of EGFR signaling. The D-raf example illustrates how different embryonic phenotypes can be observed depending on the level of either maternal or zygotic gene activity present at a specific developmental ...
Transgenic Tobacco Plant Expressing Environmental E. coli merA
... air, water, and land. These activities can increase local mercury levels several thousand folds above background levels. Microorganisms in contaminated environments have developed resistance to mercury and are playing a major role in natural decontamination. The most important detoxification mechani ...
... air, water, and land. These activities can increase local mercury levels several thousand folds above background levels. Microorganisms in contaminated environments have developed resistance to mercury and are playing a major role in natural decontamination. The most important detoxification mechani ...
- Journal of Clinical Neurology
... region have increased the rate of mutation detection and involved searching many novel sequence variants outside the three mutational hot spots,15,16 with most being reported as point missense mutations. Here we report for the first time the presence of an unusual double RYR1 mutation (Arg2435His an ...
... region have increased the rate of mutation detection and involved searching many novel sequence variants outside the three mutational hot spots,15,16 with most being reported as point missense mutations. Here we report for the first time the presence of an unusual double RYR1 mutation (Arg2435His an ...
Copenhagen1 - Buffalo Ontology Site
... individual gene products; examples: transcription factor, DNA helicase Biological Process Ontology: broad biological goals accomplished by ordered assemblies of molecular functions; examples: mitosis, purine metabolism ...
... individual gene products; examples: transcription factor, DNA helicase Biological Process Ontology: broad biological goals accomplished by ordered assemblies of molecular functions; examples: mitosis, purine metabolism ...
Genetic algorithms with multi-parent recombination
... scanning and diagonal crossover that generalize uniform, respecively n-point crossovers. In this paper we concentrate on the gene scanning mechanism and we perform extensive tests to observe the effect of different numbers of parents on the performance of the GA. We consider different problem types, ...
... scanning and diagonal crossover that generalize uniform, respecively n-point crossovers. In this paper we concentrate on the gene scanning mechanism and we perform extensive tests to observe the effect of different numbers of parents on the performance of the GA. We consider different problem types, ...
Site-specific recombinase technology
Nearly every human gene has a counterpart in the mouse (regardless of the fact that a minor set of orthologues had to follow species specific selection routes). This made the mouse the major model for elucidating the ways in which our genetic material encodes information. In the late 1980s gene targeting in murine embryonic stem (ES-)cells enabled the transmission of mutations into the mouse germ line and emerged as a novel option to study the genetic basis of regulatory networks as they exist in the genome. Still, classical gene targeting proved to be limited in several ways as gene functions became irreversibly destroyed by the marker gene that had to be introduced for selecting recombinant ES cells. These early steps led to animals in which the mutation was present in all cells of the body from the beginning leading to complex phenotypes and/or early lethality. There was a clear need for methods to restrict these mutations to specific points in development and specific cell types. This dream became reality when groups in the USA were able to introduce bacteriophage and yeast-derived site-specific recombination (SSR-) systems into mammalian cells as well as into the mouse