Figures and figure supplements
... Figure 2—figure supplement 4. ChIP-seq profiles of H3K4me3 and total histone H3 across high-variance and low-variance genes. (A) Developmental expression profile, from early cleavage to adult, of the highly expressed high-variance genes (n = 1066). Expression levels were measured by CEL-seq and resc ...
... Figure 2—figure supplement 4. ChIP-seq profiles of H3K4me3 and total histone H3 across high-variance and low-variance genes. (A) Developmental expression profile, from early cleavage to adult, of the highly expressed high-variance genes (n = 1066). Expression levels were measured by CEL-seq and resc ...
The murine homologue of HIRA, a DiGeorge
... various laboratories. These attempts led to the isolation of DGCR3 and DGCR5. DGCR3 is an open reading frame (ORF) of 260 amino acids (aa) that is interrupted by the translocation breakpoint (21). However, no cDNAs were isolated and expression studies were only informative under low stringency condi ...
... various laboratories. These attempts led to the isolation of DGCR3 and DGCR5. DGCR3 is an open reading frame (ORF) of 260 amino acids (aa) that is interrupted by the translocation breakpoint (21). However, no cDNAs were isolated and expression studies were only informative under low stringency condi ...
ACLS CH05 - CTCE Moodle
... • An enzyme is used to cut the DNA strands into segments. • DNA is removed by using a centrifuge to separate the heavier cell part away from it. • DNA is placed in a solution for electrophoresis. ...
... • An enzyme is used to cut the DNA strands into segments. • DNA is removed by using a centrifuge to separate the heavier cell part away from it. • DNA is placed in a solution for electrophoresis. ...
Epidermolysis Bullosa Letalis - Center for Arab Genomic Studies
... of epidermolysis bullosa has been delineated. Specific mutations have been demonstrated in 10 different genes expressed within the dermoepidermal adhesion zone, with at least six different genes being involved in the pathogenesis of junctional epidermolysis bullosa. Herlitz junctional epidermolysis ...
... of epidermolysis bullosa has been delineated. Specific mutations have been demonstrated in 10 different genes expressed within the dermoepidermal adhesion zone, with at least six different genes being involved in the pathogenesis of junctional epidermolysis bullosa. Herlitz junctional epidermolysis ...
Horizontal transfer of non-LTR retrotransposons: artifact or rare event
... and shuffling existing genes (Lander et al., 2001). In some cases, TEs perform critical biological functions in their host (Kidwell, Lisch, 1997). For example, the preferential insertion of some retrotransposons in Drosophila at telomeric locations has removed the need for a telomerase function (Par ...
... and shuffling existing genes (Lander et al., 2001). In some cases, TEs perform critical biological functions in their host (Kidwell, Lisch, 1997). For example, the preferential insertion of some retrotransposons in Drosophila at telomeric locations has removed the need for a telomerase function (Par ...
The Novel Gene HOMOLOGOUS PAIRING
... little effect on bouquet formation (Pawlowski et al., 2004). The AHP2 of Arabidopsis (Arabidopsis thaliana) is homologous to Saccharomyces cerevisiae HOP2 (Leu et al., 1998) and S. pombe MEU13 (Nabeshima et al., 2001), which are known to act in monitoring homology between pairing partner at meiosis, ...
... little effect on bouquet formation (Pawlowski et al., 2004). The AHP2 of Arabidopsis (Arabidopsis thaliana) is homologous to Saccharomyces cerevisiae HOP2 (Leu et al., 1998) and S. pombe MEU13 (Nabeshima et al., 2001), which are known to act in monitoring homology between pairing partner at meiosis, ...
Allelic Variation at the Rht8 Locus in a 19th
... only been reported previously in a single cultivar, “Madison” [7]. The wheats with the 182 bp allele was a Canadian wheat and a German wheat called “Ringelblumen” and it does not seem that they have a shared or limited origin that might otherwise have explained why the allele has been undetected in ...
... only been reported previously in a single cultivar, “Madison” [7]. The wheats with the 182 bp allele was a Canadian wheat and a German wheat called “Ringelblumen” and it does not seem that they have a shared or limited origin that might otherwise have explained why the allele has been undetected in ...
7. Rh Blood Group System - Austin Community College
... The gene products include not only the products of each single gene, but also a combined gene product that is also antigenic. For example, the r (cde) gene that makes c and e, also makes f, (ce). This only occurs when c and e are in the cis position (on the same chromosome). The f antigen will not b ...
... The gene products include not only the products of each single gene, but also a combined gene product that is also antigenic. For example, the r (cde) gene that makes c and e, also makes f, (ce). This only occurs when c and e are in the cis position (on the same chromosome). The f antigen will not b ...
The Ethics of Reproductive Cloning
... nuclear genomes of two individuals are not combined in the same way; genetic recombination during this process occurs in a manner that does not result in a genetically unique individual. This technical and biological difference makes reproductive cloning significantly different than assisted reprodu ...
... nuclear genomes of two individuals are not combined in the same way; genetic recombination during this process occurs in a manner that does not result in a genetically unique individual. This technical and biological difference makes reproductive cloning significantly different than assisted reprodu ...
werribee secondary college vce unit planner ~ 2004
... Homework: SAC1 revision and mitosis, meiosis revision including exam questions Tuesday: Molecular genetics, the nature of the genomes, genes and the genetic code Thursday: The role of RNA in transcription and in translation for Eukaryotes Friday: SAC1: an investigation or simulation related to mitos ...
... Homework: SAC1 revision and mitosis, meiosis revision including exam questions Tuesday: Molecular genetics, the nature of the genomes, genes and the genetic code Thursday: The role of RNA in transcription and in translation for Eukaryotes Friday: SAC1: an investigation or simulation related to mitos ...
cbb752-mg-spr10-bioinfo-intro
... the computational analysis of gene sequences, macromolecular structures, and functional genomics data on a large scale. (Some topics include: ) Sequence alignment, comparative genomics and phylogenetics, biological databases, geometric analysis of protein structure, molecular-dynamics simulation, bi ...
... the computational analysis of gene sequences, macromolecular structures, and functional genomics data on a large scale. (Some topics include: ) Sequence alignment, comparative genomics and phylogenetics, biological databases, geometric analysis of protein structure, molecular-dynamics simulation, bi ...
transgenic canola - Australian Oilseeds Federation
... being tested include those encoding novel antimicrobial peptides derived from Australian native plants and from macadamia in particular. So far, transgenic plants expressing three peptides have been developed and advanced lines expressing one peptide at high levels are under evaluation for improved ...
... being tested include those encoding novel antimicrobial peptides derived from Australian native plants and from macadamia in particular. So far, transgenic plants expressing three peptides have been developed and advanced lines expressing one peptide at high levels are under evaluation for improved ...
123 Author`s personal copy
... the study of cellular processes. It relies on the observation of cells, and more specifically chromosomes, by means of microscopes. It is worth emphasizing the distinction between what is usually called “classical genetics”, on the one hand, and Mendelian theory, as I have just characterized it, on ...
... the study of cellular processes. It relies on the observation of cells, and more specifically chromosomes, by means of microscopes. It is worth emphasizing the distinction between what is usually called “classical genetics”, on the one hand, and Mendelian theory, as I have just characterized it, on ...
T-box-mediated control of the anabolic proline biosynthetic genes of
... Henkin, 2008; Vitreschak et al., 2008; Wels et al., 2008; Winkler, 2007). The amino acid specificity of a given T-box system is conferred through a single codon, the specifier (Grundy & Henkin, 1993), which is present in the 59untranslated region of each T-box-controlled gene (Foy et al., 2010; Gree ...
... Henkin, 2008; Vitreschak et al., 2008; Wels et al., 2008; Winkler, 2007). The amino acid specificity of a given T-box system is conferred through a single codon, the specifier (Grundy & Henkin, 1993), which is present in the 59untranslated region of each T-box-controlled gene (Foy et al., 2010; Gree ...
123 Author`s personal copy
... according to which chromosomes are the physical basis of genes. From the moment when this technique was designed, the construction and analysis of the genetic maps of Drosophila melanogaster became the object of a research program on which the geneticists’ efforts concentrated for at least two decad ...
... according to which chromosomes are the physical basis of genes. From the moment when this technique was designed, the construction and analysis of the genetic maps of Drosophila melanogaster became the object of a research program on which the geneticists’ efforts concentrated for at least two decad ...
The Jumping SHOX Gene—Crossover in the Pseudoautosomal
... pseudoautosomal. The SHOX gene in the normal situation is present in two functional copies. In fact, one might consider PAR1 as a very small extra pair of autosomes (11), except that segregation in autosomes is independent of sex. Here we describe three families in which an abnormality in PAR1 segre ...
... pseudoautosomal. The SHOX gene in the normal situation is present in two functional copies. In fact, one might consider PAR1 as a very small extra pair of autosomes (11), except that segregation in autosomes is independent of sex. Here we describe three families in which an abnormality in PAR1 segre ...
Mendelian inheritance - Center of Statistical Genetics
... heterozygous affected people, and often the homozygotes are much more severely affected. Examples are achondroplasia (short-limbed dwarfism) and ...
... heterozygous affected people, and often the homozygotes are much more severely affected. Examples are achondroplasia (short-limbed dwarfism) and ...
chapter12_Meiosis and Sexual Reproduction(1
... • Nuclear division process that halves the chromosome number • Basis of sexual reproduction ...
... • Nuclear division process that halves the chromosome number • Basis of sexual reproduction ...
Changes in DNA-binding activity of transcription factors in the
... transcription. Minimum requirement for the initiation of gene transcription is binding of an appropriate set of transcription factors (TFs) to its 5’-upstream region. The combination of factors is determined by the regulatory sequences of a gene and each transcription factor recognizes DNA sequence ...
... transcription. Minimum requirement for the initiation of gene transcription is binding of an appropriate set of transcription factors (TFs) to its 5’-upstream region. The combination of factors is determined by the regulatory sequences of a gene and each transcription factor recognizes DNA sequence ...
Deconstructing the Genome: DNA at High Resolution
... technology. The most important enzymes in this tool kit are ones that operate on the DNA molecule itself: restriction enzymes that cut DNA, ligases that join two molecules together, and polymerases that synthesize new DNA strands. The most important uncatalyzed biochemical reaction is hybridization: ...
... technology. The most important enzymes in this tool kit are ones that operate on the DNA molecule itself: restriction enzymes that cut DNA, ligases that join two molecules together, and polymerases that synthesize new DNA strands. The most important uncatalyzed biochemical reaction is hybridization: ...
Applet for calculating heritability for threshold traits
... available. The online voice version includes a slide show with more than 350 slides. The voice in the voice version belongs to Anne Asp Poulsen who study English at the Copenhagen University, she also gave comments on the English style in the text and figures. The online notes include a number of li ...
... available. The online voice version includes a slide show with more than 350 slides. The voice in the voice version belongs to Anne Asp Poulsen who study English at the Copenhagen University, she also gave comments on the English style in the text and figures. The online notes include a number of li ...
NeuroGeM, a knowledgebase of genetic modifiers
... Modifiers can be grouped into aggregation modifiers and toxicity modifiers depending on the quantification method: the primary effect of aggregation modifiers is to increase or decrease aggregates while the primary effect of toxicity modifiers is to change the phenotype eventually leading to cell de ...
... Modifiers can be grouped into aggregation modifiers and toxicity modifiers depending on the quantification method: the primary effect of aggregation modifiers is to increase or decrease aggregates while the primary effect of toxicity modifiers is to change the phenotype eventually leading to cell de ...
Gene
A gene is a locus (or region) of DNA that encodes a functional RNA or protein product, and is the molecular unit of heredity. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. Most biological traits are under the influence of polygenes (many different genes) as well as the gene–environment interactions. Some genetic traits are instantly visible, such as eye colour or number of limbs, and some are not, such as blood type, risk for specific diseases, or the thousands of basic biochemical processes that comprise life.Genes can acquire mutations in their sequence, leading to different variants, known as alleles, in the population. These alleles encode slightly different versions of a protein, which cause different phenotype traits. Colloquial usage of the term ""having a gene"" (e.g., ""good genes,"" ""hair colour gene"") typically refers to having a different allele of the gene. Genes evolve due to natural selection or survival of the fittest of the alleles.The concept of a gene continues to be refined as new phenomena are discovered. For example, regulatory regions of a gene can be far removed from its coding regions, and coding regions can be split into several exons. Some viruses store their genome in RNA instead of DNA and some gene products are functional non-coding RNAs. Therefore, a broad, modern working definition of a gene is any discrete locus of heritable, genomic sequence which affect an organism's traits by being expressed as a functional product or by regulation of gene expression.