SNP Set Analysis for Detecting Disease Association Using Exon
... the past few years. They have been recently applied to genome-wide association studies (GWAS) to study the effects of both common and rare variants. The different natures of these two types of variants call for distinct methods. For common variants, association tests based on individual SNPs are sti ...
... the past few years. They have been recently applied to genome-wide association studies (GWAS) to study the effects of both common and rare variants. The different natures of these two types of variants call for distinct methods. For common variants, association tests based on individual SNPs are sti ...
PDF + SI - Biology Open - The Company of Biologists
... germplasm resources.Thus, the yellow seed coat gene must be introduced from a close species. The identification and mapping of yellow seed coat gene, as well as associated inheritance studies, are important steps in breeding yellow seed germplasm. The inheritance of yellow seeds has been studied for ...
... germplasm resources.Thus, the yellow seed coat gene must be introduced from a close species. The identification and mapping of yellow seed coat gene, as well as associated inheritance studies, are important steps in breeding yellow seed germplasm. The inheritance of yellow seeds has been studied for ...
Hierarchical Text Categorization and Its Evaluation
... disagree with one another can be together more accurate than its component classifiers • if there are L classifiers, each with an error rate < 1/2, and the errors are independent, then the prob. that the majority vote is wrong is the area under binomial distribution for more than L/2 hypotheses ...
... disagree with one another can be together more accurate than its component classifiers • if there are L classifiers, each with an error rate < 1/2, and the errors are independent, then the prob. that the majority vote is wrong is the area under binomial distribution for more than L/2 hypotheses ...
Extended Life-Span and Stress Resistance in Drosophila
... Not all the InR alleles extend longevity because the gene is highly variable. • Some alleles produced developmental defects that carry over into adults. ...
... Not all the InR alleles extend longevity because the gene is highly variable. • Some alleles produced developmental defects that carry over into adults. ...
Transgene inheritance in plants
... A brief review of the patterns of transgene inheritance Agrobacterium-mediated transformation usually produces transgenic plants with a low copy number and the transgenes are transmitted to progeny according to Mendelian (HORSCH et al. 1984, BUDAR et al. 1986) and in some cases non-Mendelian inherit ...
... A brief review of the patterns of transgene inheritance Agrobacterium-mediated transformation usually produces transgenic plants with a low copy number and the transgenes are transmitted to progeny according to Mendelian (HORSCH et al. 1984, BUDAR et al. 1986) and in some cases non-Mendelian inherit ...
Genetics The Science of Heredity student version
... to see and distinguish. • He crossed plants with two different traits, for example purple flowers with white flowers. • He started his experiments with purebred plants. • Purebred plants ALWAYS produce offspring with the same trait as the parents. For example, if the parents are both tall, all offsp ...
... to see and distinguish. • He crossed plants with two different traits, for example purple flowers with white flowers. • He started his experiments with purebred plants. • Purebred plants ALWAYS produce offspring with the same trait as the parents. For example, if the parents are both tall, all offsp ...
operon
... Translation to Be Controlled by Small Molecule Interactions with RNA • Small molecules can regulate gene expression by binding to special sites in mRNA called riboswitches • Binding of the molecule to its riboswitch triggers changes in mRNA shape that affect transcription or translation • Riboswitch ...
... Translation to Be Controlled by Small Molecule Interactions with RNA • Small molecules can regulate gene expression by binding to special sites in mRNA called riboswitches • Binding of the molecule to its riboswitch triggers changes in mRNA shape that affect transcription or translation • Riboswitch ...
Isolation and characterization of a repeated sequence (RPS1) of
... were virtually identical; however, one or two chromosomes were variable in size (Asakura et al., 1991). In virtually all cases, the chromosome that varied in size was chromosome 2. This suggested that chromosome 2 is too variable to be useful for distinguishing between strains. A similar variable ch ...
... were virtually identical; however, one or two chromosomes were variable in size (Asakura et al., 1991). In virtually all cases, the chromosome that varied in size was chromosome 2. This suggested that chromosome 2 is too variable to be useful for distinguishing between strains. A similar variable ch ...
Origin and evolution of the slime molds (Mycetozoa)
... and b-tubulin trees place them together as a single coherent (monophyletic) group, closely related to the animal–fungal clade. We have sequenced the elongation factor-1a genes from one member of each division of the Mycetozoa, including Dictyostelium discoideum, for which cDNA sequences were previou ...
... and b-tubulin trees place them together as a single coherent (monophyletic) group, closely related to the animal–fungal clade. We have sequenced the elongation factor-1a genes from one member of each division of the Mycetozoa, including Dictyostelium discoideum, for which cDNA sequences were previou ...
Genomic Analysis of Arabidopsis Thaliana
... Arabidopsis DNA in 1984. Most of the genome was found to be composed of singlecopy sequences (50–57%), with repetitive sequences (23–27%) derived primarily from chloroplast DNA. The haploid Arabidopsis nuclear genome was calculated to be 70 Mb. Compared to more recent estimates of 115 Mb for single- ...
... Arabidopsis DNA in 1984. Most of the genome was found to be composed of singlecopy sequences (50–57%), with repetitive sequences (23–27%) derived primarily from chloroplast DNA. The haploid Arabidopsis nuclear genome was calculated to be 70 Mb. Compared to more recent estimates of 115 Mb for single- ...
Sheared DNA fragment sizing: comparison of techniques
... Fig. 4 Size Distribution of Sheared DNA Fragments. Panels a, b and c show the relative number of DNA molecules corresponding to given length increments (base pairs) as determined by Kleinschmidt EM, Adsorption EM and gel electrophoresis procedures, respectively. Panels d, e and f show the relative m ...
... Fig. 4 Size Distribution of Sheared DNA Fragments. Panels a, b and c show the relative number of DNA molecules corresponding to given length increments (base pairs) as determined by Kleinschmidt EM, Adsorption EM and gel electrophoresis procedures, respectively. Panels d, e and f show the relative m ...
Basic sequence analyses and submission
... R2) do not have vector because the primers were designed within the cloned segment. 5. Use BLAST 2 sequences to Align M13_F with F1 http://www.ncbi.nlm.nih.gov/blast/bl2seq/wblast2.cgi (create a bookmark for this site) Copy the M13_F sequence in the Sequence 1 window and the F1 sequence in the Seque ...
... R2) do not have vector because the primers were designed within the cloned segment. 5. Use BLAST 2 sequences to Align M13_F with F1 http://www.ncbi.nlm.nih.gov/blast/bl2seq/wblast2.cgi (create a bookmark for this site) Copy the M13_F sequence in the Sequence 1 window and the F1 sequence in the Seque ...
Phylogenetic analysis of the insect order Odonata using 28S and
... however, Kjer noted that the sequence diversity of this gene was very low in the Odonata, suggesting that his result may not be entirely reliable. Lohmann (1996) provided morphological evidence for the nonmonophyly of the entire Anisozygoptera (including fossil taxa) and proposed the transfer of ani ...
... however, Kjer noted that the sequence diversity of this gene was very low in the Odonata, suggesting that his result may not be entirely reliable. Lohmann (1996) provided morphological evidence for the nonmonophyly of the entire Anisozygoptera (including fossil taxa) and proposed the transfer of ani ...
Книжечка
... material is mostly included in a single, closed, circular molecule of DNA, which resides in a central portion of the cell, unbounded by membranes. In eukaryotes, by contrast, a double membrane – the nuclear membrane, surrounds the nucleus. 3. A semifluid matrix called the cytoplasm occupies the volu ...
... material is mostly included in a single, closed, circular molecule of DNA, which resides in a central portion of the cell, unbounded by membranes. In eukaryotes, by contrast, a double membrane – the nuclear membrane, surrounds the nucleus. 3. A semifluid matrix called the cytoplasm occupies the volu ...
Resources for the map-based cloning of tga1
... We sequenced the tga1 promoter and coding regions for a set of 16 diverse landraces of maize and 12 teosinte individuals (Z. mays ssp. parviglumis) and the outgroup Zea diploperennis (Genbank AY883436-AY883558) using the PCR primers and conditions listed above. PCR products from Z. diploperennis wer ...
... We sequenced the tga1 promoter and coding regions for a set of 16 diverse landraces of maize and 12 teosinte individuals (Z. mays ssp. parviglumis) and the outgroup Zea diploperennis (Genbank AY883436-AY883558) using the PCR primers and conditions listed above. PCR products from Z. diploperennis wer ...
Section 11-1
... how do the results of your tosses compare? How about the results of your partner’s tosses? How close was each set of results to what was expected? 2. Add your results to those of your partner to produce a total of 20 tosses. Assuming that you expect 10 heads and 10 tails in 20 tosses, how close are ...
... how do the results of your tosses compare? How about the results of your partner’s tosses? How close was each set of results to what was expected? 2. Add your results to those of your partner to produce a total of 20 tosses. Assuming that you expect 10 heads and 10 tails in 20 tosses, how close are ...
Quantitative RT–PCR Platform to Measure Transcript Levels of C
... candidates in silico or in vivo; either one of these two methods may be used to obtain candidates for primary metabolismrelated genes in durum wheat. This candidate identification is helpful as a first step towards constructing networks controlling plant growth and development, or for understanding ...
... candidates in silico or in vivo; either one of these two methods may be used to obtain candidates for primary metabolismrelated genes in durum wheat. This candidate identification is helpful as a first step towards constructing networks controlling plant growth and development, or for understanding ...
Mark Scheme - Unit F215 - Control, genomes and
... FA in guidance column means: Mark the first answer. If the answer is correct and an additional answer is given that is incorrect or contradicts the correct answer then = 0 marks. Apply the same reasoning where the instruction is to mark the first 2 suggestions. ACCEPT incorrect spellings if they are ...
... FA in guidance column means: Mark the first answer. If the answer is correct and an additional answer is given that is incorrect or contradicts the correct answer then = 0 marks. Apply the same reasoning where the instruction is to mark the first 2 suggestions. ACCEPT incorrect spellings if they are ...
lecture - Berkeley MCB
... regulation, is really like • Trans-acting factors do not distribute in the nucleus based on the primary sequence of the genome: some factors fail to bind most genes that have sequences waiting for them, and other factors bind a large number of genes that do NOT have sequences for them • Even when a ...
... regulation, is really like • Trans-acting factors do not distribute in the nucleus based on the primary sequence of the genome: some factors fail to bind most genes that have sequences waiting for them, and other factors bind a large number of genes that do NOT have sequences for them • Even when a ...
Pax8, a murine paired box gene expressed in the developing
... mouse embryo. The expression pattern is compared with that of the Pax2 gene, whose paired domain shows an extensive homology to the paired domain of Pax8. Comparison of the spatial pattern of expression of both genes in the developing metanephros is especially instructive. The morphogenesis of the m ...
... mouse embryo. The expression pattern is compared with that of the Pax2 gene, whose paired domain shows an extensive homology to the paired domain of Pax8. Comparison of the spatial pattern of expression of both genes in the developing metanephros is especially instructive. The morphogenesis of the m ...
Prevention of DNA Rereplication Through a Meiotic Recombination
... kinase inhibitor Sic1 during meiosis can trigger extra rounds of DNA replication. When programmed DNA double-strand breaks are generated but not repaired due to absence of DMC1, a pathway involving the checkpoint gene RAD17 prevents this DNA rereplication. Further genetic analysis has now reveale ...
... kinase inhibitor Sic1 during meiosis can trigger extra rounds of DNA replication. When programmed DNA double-strand breaks are generated but not repaired due to absence of DMC1, a pathway involving the checkpoint gene RAD17 prevents this DNA rereplication. Further genetic analysis has now reveale ...
Gibberellin Signaling: Biosynthesis, Catabolism, and
... biosynthesis during seed germination may be part of the mechanism that modulates the synthesis of bioactive GAs by regulating the transport of intermediate(s) between cells. Alternatively, this phenomenon may be simply the evolutionary consequence of this pathway. When detailed knowledge of the loca ...
... biosynthesis during seed germination may be part of the mechanism that modulates the synthesis of bioactive GAs by regulating the transport of intermediate(s) between cells. Alternatively, this phenomenon may be simply the evolutionary consequence of this pathway. When detailed knowledge of the loca ...
Methods for detection of point mutations
... [1]. When low amounts of mutant alleles are analyzed in a large background of wild-type DNA, sensitivity can be increased by separation and detection of fluorescencelabeled fragments on a DNA sequencer [31]. Detectable mutations. In principle, all possible mutations are detectable by CCM [1, 30]. It ...
... [1]. When low amounts of mutant alleles are analyzed in a large background of wild-type DNA, sensitivity can be increased by separation and detection of fluorescencelabeled fragments on a DNA sequencer [31]. Detectable mutations. In principle, all possible mutations are detectable by CCM [1, 30]. It ...
rpoB gene sequence-based characterization of emerging non
... and to the description of new clinical forms due to known NTM. However, 16S rRNA gene sequence-based description of novel mycobacterial taxa is still a matter of debate. ...
... and to the description of new clinical forms due to known NTM. However, 16S rRNA gene sequence-based description of novel mycobacterial taxa is still a matter of debate. ...
Ch. 14 Mendelian Genetics
... • The traits he studied were, in fact, on nonhomologous chromosomes ...
... • The traits he studied were, in fact, on nonhomologous chromosomes ...
Gene
A gene is a locus (or region) of DNA that encodes a functional RNA or protein product, and is the molecular unit of heredity. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. Most biological traits are under the influence of polygenes (many different genes) as well as the gene–environment interactions. Some genetic traits are instantly visible, such as eye colour or number of limbs, and some are not, such as blood type, risk for specific diseases, or the thousands of basic biochemical processes that comprise life.Genes can acquire mutations in their sequence, leading to different variants, known as alleles, in the population. These alleles encode slightly different versions of a protein, which cause different phenotype traits. Colloquial usage of the term ""having a gene"" (e.g., ""good genes,"" ""hair colour gene"") typically refers to having a different allele of the gene. Genes evolve due to natural selection or survival of the fittest of the alleles.The concept of a gene continues to be refined as new phenomena are discovered. For example, regulatory regions of a gene can be far removed from its coding regions, and coding regions can be split into several exons. Some viruses store their genome in RNA instead of DNA and some gene products are functional non-coding RNAs. Therefore, a broad, modern working definition of a gene is any discrete locus of heritable, genomic sequence which affect an organism's traits by being expressed as a functional product or by regulation of gene expression.