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Mendel 2
Mendel 2

... Color blindness: Allele for color vision on X chromosome If mother donates X with colorblind allele, Son will be color blind as Y has NO allele for color vision Red-Green color blindness fairly common Hemophilia: Inability to form blood clots, can bleed to death Rare recessive allele So rare women h ...
(Microsoft PowerPoint - BehavGenTopic03BeyondMendel.ppt
(Microsoft PowerPoint - BehavGenTopic03BeyondMendel.ppt

... offspring independently of each other. The result is that new combinations of genes present in neither parent are possible.  Today, we know this is due to the fact that the genes for independently assorted traits are located on different chromosomes. ...
Chromosomes Eukaryote
Chromosomes Eukaryote

... internal organs ...
Chapter 5
Chapter 5

... Ex. What possible genotypes will the offspring have if the parents’ blood types are O and AB? Answer: AO or BO. ...
Homework #2
Homework #2

... A species has 2n = 20 chromosomes. How many chromosomes will be found per cell in each of the following mutants? a. b. c. d. e. ...
Gene Expression - Valhalla High School
Gene Expression - Valhalla High School

... constitution (the genome) of a cell, an individual or an organism. The genotype is all of the genes within your cells. Only identical twins (or tripets, etc.) have the same genotype. ...
CHAPTER 14: Genes in Action Essential Ideas
CHAPTER 14: Genes in Action Essential Ideas

... Gene-a segment of DNA whose nucleotide sequence codes for a protein. Mutation - Changes in the nucleotide sequence of a gene’s DNA Mutagens cause mutations, include environmental factors ike chemicals, X-rays, and UV light Genetic Mutations – single or small changes to individual genes DNA sequence ...
HumanGenetics
HumanGenetics

... Occurs when either homologues fail to separate during anaphase I of meiosis, or sister chromatids fail to separate during anaphase II. The result is that one gamete has 2 copies of one chromosome and the other has no copy of that chromosome. (The other chromosomes are distributed normally.) If eithe ...
Bio 130 – Quiz April 11
Bio 130 – Quiz April 11

... mammals than in other vertebrates. B. Translocations and inversions are not deleterious because no genes are lost in the organism. C. Chromosomal rearrangements are more likely to occur during mitosis than during meiosis. D. An individual that is homozygous for a deletion of a certain gene is likely ...
Genetics - TeacherWeb
Genetics - TeacherWeb

... -Males determine the sex of the child since ½ of their sperm get the X and ½ get the Y -Any information on the X chromosome will appear in males, whether recessive or dominant; females require 2 recessive alleles to show a recessive trait -Information solely on the Y chromosome are called holandric ...
Gene mutations - mccombsscience
Gene mutations - mccombsscience

... DOG BIT THE CAT.  THE DOG BIT THE CAR. ...
Chromosomal Basis of Inheritance
Chromosomal Basis of Inheritance

... While those from this will produce a patch of black fur ...
Chp 12 Notes
Chp 12 Notes

... 1. Pedigrees: a diagram that shows how a trait is inherited over several generations a. Explain Key on Example on page 241 2. Patterns of Inheritance: the expression of genes over generations a. Carriers: an individual that has one copy of a recessive allele 1. don't show trait, but can pass it on t ...
Hypothesis: Variations in the rate of DNA replication determine the
Hypothesis: Variations in the rate of DNA replication determine the

... The existence of two identical chromosomes within the same cell in which genes and higher order structures compete for limited resources is a symmetrybreaking situation previously proposed to lead to differentiation. Recent experiments are consistent with an intimate relationship between metabolism ...
SexLinked
SexLinked

... All X chromosomes have locations for the genes for hemophilia, as well as color-blindness and other sex-linked traits. Therefore, we still use the system of letters, such as E and e, to represent forms of these genes as superscripts on the X chromosome. For example, the normal gene for blood clottin ...
Chapter 31: Epigenetic Effects Are Inherited
Chapter 31: Epigenetic Effects Are Inherited

... • Imprinting describes • a change in a gene or change in gene expression • occurs during passage through the sperm or egg • results in the paternal and maternal alleles having different properties (differences in gene expression) in the very early embryo. ...
Show the cross between a white eyed male and
Show the cross between a white eyed male and

... • causes mental retardation • named because the X chromosome had an odd appearance - the tip of the chromosome seemed to be attached only by a small thread • the number of repeats of the gene determines the severity of the disease ...
Civics – Unit 1 Jeopardy - Frontenac Secondary School
Civics – Unit 1 Jeopardy - Frontenac Secondary School

... an unaffected father in a Xlink dominant disorder ...
Principles of Biology Lake Tahoe Community College
Principles of Biology Lake Tahoe Community College

... 2. wild type 2. behavior of gene w/ behavior of chromosomes 3. gene for eye color found on sex chromosome II. Linked genes A. near each other on same chromosome, tend to be inherited together 1. Linked genes – chromosomal basis a. X linked b. Y linked 2. X inactivation in female mammals a. one chrom ...
Types of Chromosome Mutations
Types of Chromosome Mutations

... translocation can show variegated phenotype for that gene. ...
Until now our analysis of genes has focused on gene function as
Until now our analysis of genes has focused on gene function as

... mapping point mutations at the resolution of single nucleotide pairs. We’ve taken it for granted that genes reside on chromosomes, but how do we know this?Let’s review the properties of gene segregation.Consider two different traits. ...
errors_exceptions teacher notes
errors_exceptions teacher notes

... crossing over) 3. All these can be increased by X-rays & other chemicals B. Syndromes resulting from chromosome changes 1. Down Syndrome a. aneuploid condition; most often from nondisjunction during game production in one parent b. due to 3 copies of chromosome 21 (trisomy 21) c. affects 1 in 700 ch ...
Nature Genetics - David Page Lab
Nature Genetics - David Page Lab

... evolved from a pair of ordinary autosomes. At first, sex was genetically determined by a simple diallelic system, F and M, in which the male was the heterogametic sex. b, Sex chromosome differentiation began when the proto-Y chromosome accrued at least one additional gene, that together with the M a ...
Amino Acid Substitution - UNT's College of Education
Amino Acid Substitution - UNT's College of Education

... Variation in Chromosome Number Chromosome Abnormalities ...
Lecture #6 Date - Cloudfront.net
Lecture #6 Date - Cloudfront.net

... Interesting note – the successful drug Gleevec ® prevents ATP from binding the active site of the mutant ABL protein, thus stopping the cancer cells from undergoing the cell cycle!!! ...
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Skewed X-inactivation

Skewed X chromosome inactivation occurs when the inactivation of one X chromosome is favored over the other, leading to an uneven number of cells with each chromosome inactivated. It is usually defined as one allele being found on the active X chromosome in over 75% of cells, and extreme skewing is when over 90% of cells have inactivated the same X chromosome. It can be caused by primary nonrandom inactivation, either by chance due to a small cell pool or directed by genes, or caused by secondary nonrandom inactivation, which occurs by selection. Most females will have some levels of skewing. It is relatively common in adult females; around 35% of women have skewed ratio over 70:30, and 7% of women have an extreme skewed ratio of over 90:10. This is of medical significance due to the potential for the expression of disease genes present on the X chromosome that are normally not expressed due to random X inactivation. X chromosome inactivation occurs in females to provide dosage compensation between the sexes. If females kept both X chromosomes active they would have twice the number of active X genes than males, who only have one copy of the X chromosome. At approximately the time of implantation (see Implantation (human embryo), one of the two X chromosomes is randomly selected for inactivation. The cell undergoes transcriptional and epigenetic changes to ensure this inactivation is permanent. All progeny from these initial cells will maintain the inactivation of the same chromosome, resulting in a mosaic pattern of cells in females.
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