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1998-2000
1998-2000

... with coronary artery disease. For some people, changes in lifestyle, such as dietary changes, not smoking and regular exercise, can result in great improvements in health. In other cases, medication prescribed for high blood pressure or other conditions can make a significant difference. Sometimes, ...
Impaired Myocardial Oxygenation Response to Stress in Patients
Impaired Myocardial Oxygenation Response to Stress in Patients

... Methods and Results-—Fifty-three subjects (23 subjects with CKD, 10 RT recipients, 10 hypertensive (HT) controls, and 10 normal controls without known coronary artery disease) underwent CMR scanning. All groups had cine and BOLD CMR at 3 T. The RT and HT groups also had late gadolinium CMR to assess ...
THE ROLE OF THE THEBESIAN VESSELS IN THE CIRCULATION
THE ROLE OF THE THEBESIAN VESSELS IN THE CIRCULATION

... clinicians began to correlate the postmortem with the clinical findings. The belief that special substances other than blood circulated in the blood vessels had begun to disappear. This interest in the circulation of the heart walls was given a fresh stimulus by the publications of Raymond Vieussens ...
Concomitant Administration of Clopidogrel With Statins or Calcium
Concomitant Administration of Clopidogrel With Statins or Calcium

... attenuate the pharmacodynamic effects of clopidogrel. Methods The TRITON–TIMI 38 (Trial to Assess Improvement in Therapeutic Outcomes by Optimizing Platelet Inhibition With Prasugrel–Thrombolysis in Myocardial Infarction 38) enrolled 13,608 patients with an acute coronary syndrome (ACS) and planned ...
Percutaneous mitral valve repair: an overview of new interventional
Percutaneous mitral valve repair: an overview of new interventional

... period of many months or even potentially years, to replace rods with rods of greater stiffness if the degree of MR worsens. The Phase I trial has been carried out in a small number of patients, and ongoing experience and larger Phase I trials are anticipated. As was the case with the Monarc device, ...
1.-Cardiology - PGXL Laboratories
1.-Cardiology - PGXL Laboratories

... CYP2C19 Poor Metabolizer (PM): This patient’s genotype is consistent with significantly reduced CYP2C19 enzymatic activity. PMs are at increased risk of drug-induced side effects due to diminished drug elimination of active drugs. Patients with no CYP2C19 function (PMs) taking clopidogrel lack adequ ...
Relation between regional function and coronary blood - AJP
Relation between regional function and coronary blood - AJP

... whereas dobutamine has also been used successfully to assess myocardial viability in patients with chronic coronary stenoses and reduced %WT (1, 19, 21, 29), there are few data regarding the pathophysiological basis for its use. We have developed a closed-chest canine model of multivessel chronic co ...
PDF Article
PDF Article

... Analysis of intramural coronary arteries. Asse ssment of intramural coronary artery anatomy was confined to those arterie s « I ,500 f-L in diameter) that were viewed in cross section (transverse cut) without obvious obliquity and that did not appear to be branches of another intramural vessel, or p ...
Incidence of, predictors for, and mortality associated with malignant
Incidence of, predictors for, and mortality associated with malignant

... Background: The incidence of non-ST elevation myocardial infarction (NSTEMI) is increasing. While life-threatening ventricular arrhythmias have been well-documented in patients with ST elevation myocardial infarction (STEMI), their incidence and importance in NSTEMI have not been examined in similar ...
Diagnosis of Stable Ischemic Heart Disease: Summary of a Clinical
Diagnosis of Stable Ischemic Heart Disease: Summary of a Clinical

... diagnosis of stable known or suspected ischemic heart disease (IHD). This is the first of 2 guidelines addressing stable IHD; the second guideline addresses the management of patients with stable IHD (1). Internists and other primary care physicians are the target audiences for this guideline. The t ...
NSTEMI standing orders
NSTEMI standing orders

... efficacy and providing data on bleeding risks used a loading dose of 300 mg orally followed by a daily oral maintenance dose of 75 mg. Higher oral loading doses such as 600 or 900 mg of clopidogrel more rapidly inhibit platelet aggregation and achieve a higher absolute level of inhibition of platele ...
Print - Circulation
Print - Circulation

... differences in interpretation of results. All investigators agree that, when watery solutions or suspensions of very fine particles like India ink are injected into one coronary artery, they appear promptly in the other coronary arteries and their branches.'22 Such materials, however, traverse the c ...
Cardiovascular risks associated with non-‐aspirin non
Cardiovascular risks associated with non-‐aspirin non

... effects  of  NSAIDs,  followed  by  a  description  of  the  established   cardiovascular  risks  of  NSAIDs,  and  ends  with  a  review  of  the   existing  literature  in  relation  to  the  hypotheses  and  objectives  of   the  dis ...
Dyspnea in Post Percutaneous Transluminal Coronary Angioplasty
Dyspnea in Post Percutaneous Transluminal Coronary Angioplasty

... Coronary Syndrome (ACS). These patients require Dual Antiplatelet Therapy (DAPT) with a P2Y12 receptor inhibitor like ticagrelor or clopidogrel in combination with aspirin (a cyclooxegenase inhibitor) for 1 year after PTCA. Antiplatelet drugs are those drugs which prevents the blood platelets from s ...
2014 ACC/AHA Guideline on Perioperative Cardiovascular
2014 ACC/AHA Guideline on Perioperative Cardiovascular

... methodology is the development of recommendations on the basis of all available evidence. Literature searches focus on randomized controlled trials (RCTs) but also include registries, nonrandomized comparative and descriptive studies, case series, cohort studies, systematic reviews, and expert opini ...
Full Text  - Archives of Cardiovascular Imaging
Full Text - Archives of Cardiovascular Imaging

... Keywords: Coronary Artery Disease, Echocardiography, Tissue Doppler Imaging, Post-Systolic Shortening ...
GUIDELINE FOR STABLE CORONARY ARTERY DISEASE
GUIDELINE FOR STABLE CORONARY ARTERY DISEASE

... 1.c. Catheter revascularization: clinical indications.....................................................................................page 26 1.c.1. One-vessel disease patients............................................................................................................page 26 1.c. ...
Myocardial perfusion scintigraphy using rubidium
Myocardial perfusion scintigraphy using rubidium

... As the evidence accumulates for the benefits of managing coronary artery disease (CAD) based upon its functional significance, there has been a shift from an approach based upon the coronary anatomy.1,2 Although fractional flow reserve (FFR) provides an invasive assessment of coronary function, non- ...
Acute myocardial infarction complicated by cardiogenic shock: an
Acute myocardial infarction complicated by cardiogenic shock: an

... mortality prior to the establishment of an algorithm-based program in July 2010. We hypothesized that an algorithm based ECMO program improves the outcome of patients with acute myocardial infarction complicated with cardiogenic shock. Methods: Between March 2003 and July 2013, 29 patients underwent ...
Correlation between P Wave Dispersion, QRS Duration and QT
Correlation between P Wave Dispersion, QRS Duration and QT

... Alexandria University Hospitals from first of January 2012 to end of August 2012. An informed consent was taken from relatives of every patient included in the study. This study was approved by ethical committee of Alexandria Faculty of Medicine. Results: During the observation up to 5 days, 1 patie ...
Relationship of MRI delayed contrast enhancement to irreversible
Relationship of MRI delayed contrast enhancement to irreversible

... normal, P,0.001). In RII, wall thickening before, during, and after inflation of the occluder for 15 minutes was 3565%, 168%, and 21610% and Doppler flow was 19.865.3, 0.260.5, and 56.3617.7 (peak hyperemia) cm/s, respectively, confirming occlusion, transient ischemia, and reperfusion. Gd-DTPA– enha ...
Print - Circulation
Print - Circulation

... concept that extrasystole-induced short-to-long cycle length changes may promote such dispersion,77'78 as manifest in electrocardiographic recordings that reveal the onset of sustained VT following a postextrasystolic sinus beat.19'40 This phenomenon could facilitate occurrence of sustained VT regar ...
Heart Rate Variability in Time Domain after Acute Myocardial Infarction
Heart Rate Variability in Time Domain after Acute Myocardial Infarction

... Affcrciit signals that originate from scvcrnl sciisors located in the carotid sinus, the aorta, the grcat veins and both atria and vcntriclcs, give input to a variety of cardio-vascular rcflcscs controlling heart and circulation. This includes baroreceptors measuring blood pressure as well as chemor ...
What is the benefit of CT-based attenuation correction in myocardial
What is the benefit of CT-based attenuation correction in myocardial

... in identifying multi-vessel CAD [25]. An example is given in Figure 2. As regards the prognostic value of CT-AC, previous studies have yielded con icting results. Pazhekonttil et al. (2011) studied 876 patients with 99mTc-MIBI for a follow-up period of 2.3±0.6 years. They found that patients with ze ...
Interventional cardiac catheterization
Interventional cardiac catheterization

... With balloon valvuloplasty, hemodynamic and clinical improvement can also be achieved in the neonate (29,69,152). Recent studies of balloon valvuloplasty have shown it to be as effective and safe as surgical transventricular dilation in the treatment of critical aortic stenosis in newborn, with an e ...
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Drug-eluting stent



A drug-eluting stent (DES) is a peripheral or coronary stent (a scaffold) placed into narrowed, diseased peripheral or coronary arteries that slowly releases a drug to block cell proliferation. This prevents fibrosis that, together with clots (thrombi), could otherwise block the stented artery, a process called restenosis. The stent is usually placed within the peripheral or coronary artery by an interventional cardiologist or interventional radiologist during an angioplasty procedure.Drug-eluting stents in current clinical use were approved by the FDA after clinical trials showed they were statistically superior to bare-metal stents for the treatment of native coronary artery narrowings, having lower rates of major adverse cardiac events (usually defined as a composite clinical endpoint of death + myocardial infarction + repeat intervention because of restenosis). The first drug-eluting stents to be approved in Europe and the U.S. were coated with paclitaxel or an mTOR inhibitor, such as sirolimus.
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