Electrocardiographic And Vectorcardiographic Criteria
... enzymatic and cardiac catheterization evidence of infarction. When coupled with a clinical history of infarction, the presence of significant amounts of MBcreatine kinase in the serum is a sensitive and specific indicator of acute myocardial infarction.27 This clinical presentation was accompanied b ...
... enzymatic and cardiac catheterization evidence of infarction. When coupled with a clinical history of infarction, the presence of significant amounts of MBcreatine kinase in the serum is a sensitive and specific indicator of acute myocardial infarction.27 This clinical presentation was accompanied b ...
Chronic Coronary Artery Constriction Leads to Moderate
... 1 ml of cadmium chloride (100 mM, i.v.). The heart was then perfused retrogradely through the abdominal aorta as previously described (15). Perfusion pressure was adjusted to the mean arterial pressure measured in vivo. The left ventricular chamber was filled with fixative and kept at a pressure equ ...
... 1 ml of cadmium chloride (100 mM, i.v.). The heart was then perfused retrogradely through the abdominal aorta as previously described (15). Perfusion pressure was adjusted to the mean arterial pressure measured in vivo. The left ventricular chamber was filled with fixative and kept at a pressure equ ...
silent ischemia and diabetes mellitus
... repeated episodes of SMI could lead to progressive fibrosis and development of left ventricular dysfunction, and to life-threatening arrhythmias, especially in patients with an electrical substrate for arrhythmias. SMI is associated with an increase in coronary risk that may be reversible with appro ...
... repeated episodes of SMI could lead to progressive fibrosis and development of left ventricular dysfunction, and to life-threatening arrhythmias, especially in patients with an electrical substrate for arrhythmias. SMI is associated with an increase in coronary risk that may be reversible with appro ...
Management of acute myocardial infarction in patients presenting
... 2. The pathogenesis of ST-segment elevation acute myocardial infarction Most cases of STEMI are caused by an occlusion of a major coronary artery. Coronary occlusion and reduction in coronary blood flow are usually due to physical disruption of an atherosclerotic plaque with subsequent formation of ...
... 2. The pathogenesis of ST-segment elevation acute myocardial infarction Most cases of STEMI are caused by an occlusion of a major coronary artery. Coronary occlusion and reduction in coronary blood flow are usually due to physical disruption of an atherosclerotic plaque with subsequent formation of ...
Management of acute myocardial infarction in patients presenting with persistent ST-segment elevation
... 2. The pathogenesis of ST-segment elevation acute myocardial infarction Most cases of STEMI are caused by an occlusion of a major coronary artery. Coronary occlusion and reduction in coronary blood flow are usually due to physical disruption of an atherosclerotic plaque with subsequent formation of ...
... 2. The pathogenesis of ST-segment elevation acute myocardial infarction Most cases of STEMI are caused by an occlusion of a major coronary artery. Coronary occlusion and reduction in coronary blood flow are usually due to physical disruption of an atherosclerotic plaque with subsequent formation of ...
Relationship QRS Amplitude Changes During Exercise to
... Both the normal subjects and patients were studied first in the supine basal state and then during a graded supine bicycle exercise with up to three levels of increasing work load, each lasting 3 minutes. The test was discontinued because of any of the following: angina, more than 0.3 mV ST depressi ...
... Both the normal subjects and patients were studied first in the supine basal state and then during a graded supine bicycle exercise with up to three levels of increasing work load, each lasting 3 minutes. The test was discontinued because of any of the following: angina, more than 0.3 mV ST depressi ...
Management of acute myocardial infarction in patients presenting
... 2. The pathogenesis of ST-segment elevation acute myocardial infarction Most cases of STEMI are caused by an occlusion of a major coronary artery. Coronary occlusion and reduction in coronary blood flow are usually due to physical disruption of an atherosclerotic plaque with subsequent formation of ...
... 2. The pathogenesis of ST-segment elevation acute myocardial infarction Most cases of STEMI are caused by an occlusion of a major coronary artery. Coronary occlusion and reduction in coronary blood flow are usually due to physical disruption of an atherosclerotic plaque with subsequent formation of ...
PATTERNS OF HUMAN MYOCARDIAL OXYGEN EXTRACTION
... myocardial oxygen requirements (1, 3, 4). Case, Berglund and Sarnoff demonstrated that when coronary blood flow reserve was limited by experimental coronary constriction, myocardial extraction increased due to the combined stress of anemia and increased left ventricular work (3). The effect of exerc ...
... myocardial oxygen requirements (1, 3, 4). Case, Berglund and Sarnoff demonstrated that when coronary blood flow reserve was limited by experimental coronary constriction, myocardial extraction increased due to the combined stress of anemia and increased left ventricular work (3). The effect of exerc ...
Comparison of Thrombolysis Followed by Broad Use of
... Background—Intravenous thrombolysis remains a widely used treatment for ST-elevation myocardial infarction; however, it carries a higher risk of reinfarction than primary PCI (PPCI). There are few data comparing PPCI with thrombolysis followed by routine angiography and PCI. The purpose of the prese ...
... Background—Intravenous thrombolysis remains a widely used treatment for ST-elevation myocardial infarction; however, it carries a higher risk of reinfarction than primary PCI (PPCI). There are few data comparing PPCI with thrombolysis followed by routine angiography and PCI. The purpose of the prese ...
Coronary Heart Disease - University of Warwick
... middle childhood and increase in prevalence with age (Strong et al., 1999; Tuzcu et al., 2001). Components of the inflammatory and reparative response to injury (e.g., monocytes, smooth muscle cell proliferation) foster the deposit of lipoprotiens into cellular structures within artery walls (Ross, ...
... middle childhood and increase in prevalence with age (Strong et al., 1999; Tuzcu et al., 2001). Components of the inflammatory and reparative response to injury (e.g., monocytes, smooth muscle cell proliferation) foster the deposit of lipoprotiens into cellular structures within artery walls (Ross, ...
VEGF-C and aortic cardiomyocytes guide coronary artery stem
... nearby cardiac endothelial cells. Peritruncal vessels (coronary vessels and ASVs) and the endocardium were positive for VEGFR2 and VEGFR3 (Figure 3D), while antibodies recognizing VEGFR2 also labeled aortic endothelium (Figure 3D). VEGF-A was also expressed in the heart, but it was largely expressed ...
... nearby cardiac endothelial cells. Peritruncal vessels (coronary vessels and ASVs) and the endocardium were positive for VEGFR2 and VEGFR3 (Figure 3D), while antibodies recognizing VEGFR2 also labeled aortic endothelium (Figure 3D). VEGF-A was also expressed in the heart, but it was largely expressed ...
Detection and Imaging of Cardiac Allograft Vasculopathy
... transplant recipients. CAV occurs in approximately 30% of patients by 5 years and 50% by 10 years, and is a major cause of graft loss and death. Early detection of CAV is important because it may allow alterations in medical therapy before progression to the stage that revascularization is required. ...
... transplant recipients. CAV occurs in approximately 30% of patients by 5 years and 50% by 10 years, and is a major cause of graft loss and death. Early detection of CAV is important because it may allow alterations in medical therapy before progression to the stage that revascularization is required. ...
Endovascular Treatment of Isolated Bilateral Internal Ili
... 31 mm in the right common iliac artery (CIA). Due to lower rates of morbidity and mortality, an endovascular approach was chosen instead of open surgical repair. However, due to anatomical constraints, an endograft had to be implanted in a healthy aorta in order to support an iliac branch endograft ...
... 31 mm in the right common iliac artery (CIA). Due to lower rates of morbidity and mortality, an endovascular approach was chosen instead of open surgical repair. However, due to anatomical constraints, an endograft had to be implanted in a healthy aorta in order to support an iliac branch endograft ...
File
... clopidogrel responsiveness in 60 consecutive patients with ST-segment-elevation acute myocardial infarction (STEMI) within six hours of onset. All 60 patients received primary percutaneous coronary intervention (PCI) and were treated with 300 mg of clopidogrel followed by 75mg/day for the next 3 mon ...
... clopidogrel responsiveness in 60 consecutive patients with ST-segment-elevation acute myocardial infarction (STEMI) within six hours of onset. All 60 patients received primary percutaneous coronary intervention (PCI) and were treated with 300 mg of clopidogrel followed by 75mg/day for the next 3 mon ...
W<\
... in the coronary waterfall phenomena (or the sluicing method was introduced, which was used by Bassingthgates in the sluicing analogy), to quantitatively deter waighte et al. (3) to study capillary morphometry in the mine the process of vascular hypertrophy or remodeling left ventricle of the dog. Th ...
... in the coronary waterfall phenomena (or the sluicing method was introduced, which was used by Bassingthgates in the sluicing analogy), to quantitatively deter waighte et al. (3) to study capillary morphometry in the mine the process of vascular hypertrophy or remodeling left ventricle of the dog. Th ...
Measurements of coronary blood flow and degree of stenosis
... of myocardial saturation and desaturation and the type of calculation used to quantitate flow. If flow is indeed lower in the distribution of the anterior descending artery than in that of the circumflex artery. the rates of entry and exit of a tracer will be slower in the anterior distribution than ...
... of myocardial saturation and desaturation and the type of calculation used to quantitate flow. If flow is indeed lower in the distribution of the anterior descending artery than in that of the circumflex artery. the rates of entry and exit of a tracer will be slower in the anterior distribution than ...
Shear stress-induced vasodilation in porcine coronary - AJP
... gradient studied. Paired (two tailed) t-tests were performed to detect differences between pharmacological responses under various conditions and were also used to compare differences in coronary diameters at each of the flow steps compared with the initial diameter. The Bonferroni correction was us ...
... gradient studied. Paired (two tailed) t-tests were performed to detect differences between pharmacological responses under various conditions and were also used to compare differences in coronary diameters at each of the flow steps compared with the initial diameter. The Bonferroni correction was us ...
Developing computational methods for three
... conditions [2,3,11,20,21,23,25,27,32,43,47,48] and did not compute realistic pressure fields. Migliavacca et al. [15,19] computed three-dimensional pulsatile coronary flow and pressure in a single coronary artery by considering the intramyocardial pressure but this study was performed with an idealize ...
... conditions [2,3,11,20,21,23,25,27,32,43,47,48] and did not compute realistic pressure fields. Migliavacca et al. [15,19] computed three-dimensional pulsatile coronary flow and pressure in a single coronary artery by considering the intramyocardial pressure but this study was performed with an idealize ...
Paced ECG Morphology–Reveals More than What It Conceals
... increased r in lead V1 is very specific for anterior wall myocardial infarction in the setting of LBBB. In right ventricular pacing, these Q waves however could simply reflect differences in the lead tip position rather than myocardial infarction.1,2 Thus Q in leads V5 and V6 could be normal finding ...
... increased r in lead V1 is very specific for anterior wall myocardial infarction in the setting of LBBB. In right ventricular pacing, these Q waves however could simply reflect differences in the lead tip position rather than myocardial infarction.1,2 Thus Q in leads V5 and V6 could be normal finding ...
Regional myocardial systolic function during acute
... in all segments seen from the LV four-chamber view (ns). All patients had normal WMSI (1.0 ⫾ 0.0) as assessed from the 2-D loops (Table 3). Acute LAD ischemia. Peak systolic velocity measured by TDE decreased significantly in all septal segments and the apical lateral segment. No significant changes ...
... in all segments seen from the LV four-chamber view (ns). All patients had normal WMSI (1.0 ⫾ 0.0) as assessed from the 2-D loops (Table 3). Acute LAD ischemia. Peak systolic velocity measured by TDE decreased significantly in all septal segments and the apical lateral segment. No significant changes ...
Poor R-Wave Progression
... as early as V2. This is called early transition. At times, transition may be delayed until V4 to V5. This is called delayed transition.2 The normal R-wave height in V3 is usually greater than 2 mm. If the height of the r wave in leads V1 to V4 remains extremely small, we say there is ‘‘poor R-wave p ...
... as early as V2. This is called early transition. At times, transition may be delayed until V4 to V5. This is called delayed transition.2 The normal R-wave height in V3 is usually greater than 2 mm. If the height of the r wave in leads V1 to V4 remains extremely small, we say there is ‘‘poor R-wave p ...
Mechanism and significance of a decrease in ejection fraction
... only dunng exercise and resultmg from a decrease 10 regional wall motion was termed exercise-induced asynergy Equiltbrtum radionuchde angiography was performed after 10 VIVO labelmg of red blood cells WIth 30 mCI of technetlUm-99m A SIngle-crystal gamma-camera, equipped WIth a high sensinvity collim ...
... only dunng exercise and resultmg from a decrease 10 regional wall motion was termed exercise-induced asynergy Equiltbrtum radionuchde angiography was performed after 10 VIVO labelmg of red blood cells WIth 30 mCI of technetlUm-99m A SIngle-crystal gamma-camera, equipped WIth a high sensinvity collim ...
Management and outcome In Non ST
... Sweden and the rest of the Western world; a decrease that have multiple causes. (1-3) In spite of improvements, the incidence of acute MI has remained high and cardiovascular disease is still the leading cause of death, afflicting almost 50 % of both men and women. Coronary heart disease accounts fo ...
... Sweden and the rest of the Western world; a decrease that have multiple causes. (1-3) In spite of improvements, the incidence of acute MI has remained high and cardiovascular disease is still the leading cause of death, afflicting almost 50 % of both men and women. Coronary heart disease accounts fo ...
CORONARY COMPUTED TOMOGRAPHY ANGIOGRAPHY IN
... compared to ICA. In particular, an excellent negative predictive value has been demonstrated in several meta-analyses [3,19]. Coronary CTA has proven highly sensitive in detecting atherosclerotic plaques in the proximal segments of the coronary arteries, as compared to intravascular ultrasound [20]. ...
... compared to ICA. In particular, an excellent negative predictive value has been demonstrated in several meta-analyses [3,19]. Coronary CTA has proven highly sensitive in detecting atherosclerotic plaques in the proximal segments of the coronary arteries, as compared to intravascular ultrasound [20]. ...
Evaluation of Bi-ventricular Coronary Flow Patterns Using High
... sides of the heart in mice. Physiologic perturbations by surgical interventions such as transversal aortic constriction (TAC) and coronary arterial ligation can facilitate the in-depth exploration into the underlying mechanisms of specific disease conditions including pressure overload and myocardia ...
... sides of the heart in mice. Physiologic perturbations by surgical interventions such as transversal aortic constriction (TAC) and coronary arterial ligation can facilitate the in-depth exploration into the underlying mechanisms of specific disease conditions including pressure overload and myocardia ...
Drug-eluting stent
A drug-eluting stent (DES) is a peripheral or coronary stent (a scaffold) placed into narrowed, diseased peripheral or coronary arteries that slowly releases a drug to block cell proliferation. This prevents fibrosis that, together with clots (thrombi), could otherwise block the stented artery, a process called restenosis. The stent is usually placed within the peripheral or coronary artery by an interventional cardiologist or interventional radiologist during an angioplasty procedure.Drug-eluting stents in current clinical use were approved by the FDA after clinical trials showed they were statistically superior to bare-metal stents for the treatment of native coronary artery narrowings, having lower rates of major adverse cardiac events (usually defined as a composite clinical endpoint of death + myocardial infarction + repeat intervention because of restenosis). The first drug-eluting stents to be approved in Europe and the U.S. were coated with paclitaxel or an mTOR inhibitor, such as sirolimus.