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ACLS Pharmacology Review
ACLS Pharmacology Review

... – Class IIb if prolonged resuscitation with effective ventilation; upon return of spontaneous circulation – Class III (not useful or effective) in hypoxic lactic acidosis or hypercarbic acidosis (eg, cardiac arrest and CPR without intubation) Other Cardiac Arrest Drugs ...
ACLS Pharmacology Review
ACLS Pharmacology Review

... – Class IIb if prolonged resuscitation with effective ventilation; upon return of spontaneous circulation – Class III (not useful or effective) in hypoxic lactic acidosis or hypercarbic acidosis (eg, cardiac arrest and CPR without intubation) Other Cardiac Arrest Drugs ...
NIH Public Access
NIH Public Access

... helps to identify risk factors; 4) routine use of BAS and PGE may not be beneficial in some cases; 5) early ASO improves outcomes and reduces costs with a low mortality. Single or intramural coronary arteries remain risk factors; 6) post-ASO arrhythmias and cardiac dysfunction should raise suspicion ...
C-Reactive Protein, Interleukin-6, and Fibrinogen as Predictors of
C-Reactive Protein, Interleukin-6, and Fibrinogen as Predictors of

... Interleukin 6 (IL-6) is the major initiator of acute phase response by hepatocytes and a primary determinant of hepatic CRP production,17,18 as suggested by IL-6 – deficient animals showing impaired acute phase reaction.19 Experimental studies indicate that vascular endothelial and smooth muscle cel ...
Translational models of coronary artery disease, myocardial
Translational models of coronary artery disease, myocardial

... Development, validation and in vivo imaging studies using positron emission tomography Department of Clinical Physiology and Nuclear Medicine and Turku PET Centre, University of Turku, Turku, Finland Coronary artery disease is an atherosclerotic disease, which leads to narrowing of coronary arteries ...
Detection of Subendocardial Ischemia in the Left Anterior
Detection of Subendocardial Ischemia in the Left Anterior

... defect was defined as one in which an evident decrease in contrast enhancement within the inner one-half of the myocardial wall was visualized during the replenishment phase of contrast (Online Video 1). A transmural perfusion defect was one in which decreased contrast enhancement was observed throu ...
Longitudinal Common Carotid Artery Wall Motion
Longitudinal Common Carotid Artery Wall Motion

... for accumulation of lipoproteins into the intima (the inner layer of the arterial wall facing the blood stream). Increased adhesion of leukocytes and platelets activate formation of different molecules such as cytokines, different enzymes and growth factors. Attracted monocytes differentiate into ma ...
Full Text  - Archives of Cardiovascular Imaging
Full Text - Archives of Cardiovascular Imaging

... values similar to those in the left ventricle. Coronary angiography should be performed in accordance with the current guidelines (31, 32). Revascularization either by surgery or by percutaneous coronary intervention increases the patient’s chance of surviving cardiogenic shock. We will discuss belo ...
Left Ventricle Posterior Wall Aneurysms with Calcified Thrombus in
Left Ventricle Posterior Wall Aneurysms with Calcified Thrombus in

... failure. Dangerous ventricular arrhythmias can be seen with both true and pseudoaneurysms, as in our case (3,4). Complications of pseudoaneurysms are similar to those of a true aneurysm, but in contrast, they require emergency surgery. As both type of aneurysms present in a similar way, distinguishi ...
The Reflex Stimulation of Catecholamine Secretion during the Acute
The Reflex Stimulation of Catecholamine Secretion during the Acute

... rat stomach strip but not of the chick rectum, though both tissues were relaxed by intravenous infusions of adrenaline. This differential effect on the rat stomach strip showed secretion of noradrenaline into the circulation. The first application of lignocaine to the ischaemic heart led to a partia ...
Takotsubo Cardiomyopathy
Takotsubo Cardiomyopathy

... similar kinetics to that seen in ACS.2,4,6 High plasma catecholamines are found in a majority of patients at presentation; however, their role in the pathogenesis remains poorly understood and these are not generally measured unless there is concern about pheochromocytoma. It is not clear whether se ...
Notes CSANZ Indigenous Cardiovascular Health Conference 2009
Notes CSANZ Indigenous Cardiovascular Health Conference 2009

... composites of major cardiovascular disease (CVD) events (CVD death, non-fatal MI and stroke), and total CVD events (major CVD events, unstable angina and revascularization), MI (both fatal and nonfatal), stroke, hospitalization for heart failure, coronary death, CVD death and total mortality. The da ...
Nutritional Treatments for Acute Myocardial Infarction
Nutritional Treatments for Acute Myocardial Infarction

... thrombus formation. Intravenous administration of magnesium decreased infarct size by more than 50 percent and preserved ejection fraction.18 In rats fed a standard diet and subjected to surgical occlusion of the left coronary artery, MI occurred in 100 percent of 16 animals. Oral administration of ...
Prevalences of Anginal Symptoms and Myocardial Ischemia and
Prevalences of Anginal Symptoms and Myocardial Ischemia and

... measurement of left ventricular ejection fraction. At each visit, clinical outcomes occurring during the ...
Stress Testing in Cardiac Evaluation
Stress Testing in Cardiac Evaluation

... most commonly in patients who have had previous myocardial infarctions.40,41 Most studies demonstrated an incidence of 14 to 27%.40 – 42,45–50 Patients with anterior myocardial infarction are more likely to have exercise-induced ST-segment elevation than are those with inferior myocardial infarction ...
Assessment of coronary flow velocity with transthoracic
Assessment of coronary flow velocity with transthoracic

... for determining the indication or end points of catheterbased coronary intervention (1– 4). These measurements are usually obtained by sensor-tipped angioplasty Doppler guidewires, which are only applicable in the cardiac catheterization laboratory. Recent advances in transthoracic Doppler echocardi ...
A Meta-Analysis of Randomized Controlled Trials
A Meta-Analysis of Randomized Controlled Trials

... FORWARD, Randomized Trial to Assess Efficacy of PUFA for the Maintenance of Sinus Rhythm in Persistent Atrial Fibrillation Fish Oil Research with omega-3 for Atrial fibrillation Recurrence Delaying; GISSI ¼ Gruppo Italiano per lo Studio della Sopravvivenza nell’Infarto Miocardio; IEIS-4 ¼ Indian Exper ...
Guidelines on the management of stable angina pectoris
Guidelines on the management of stable angina pectoris

... not relieved by nitroglycerin (although it may be in the case of oesophageal spasm) and may be provoked by palpation. Non-cardiac causes of pain should be evaluated in such cases. Definitions of typical and atypical angina have been previously published11 and are summarized in Table 1. It is importan ...
Hypertensive Heart Failure
Hypertensive Heart Failure

... The relative superiority of ACE inhibitors and diuretics is not clear, as two recent large trials 53,54 have yielded conflicting results. In the ALLHAT study,53 the lisinopril group had a 19% increased risk of heart failure as compared to patients treated with chlorthalidone, whereas in the second A ...
Metabolic Response during Impending Myocardial
Metabolic Response during Impending Myocardial

... control period to 101% during ischemia and a decrease in the oxygen-extraction ratio for glucose from 33 to 25%. In patients with a severe systemic response to acute myocardial infarction, insulin suppression can be almost complete, and this will reduce the availability of glucose to myocardial cell ...
Pharmacological Therapy for Myocardial Infarction in the Elderly. An
Pharmacological Therapy for Myocardial Infarction in the Elderly. An

... (1992) showed a 13% reduction in mortality in patients aged from 56 to 64 years and a 25% reduction in mortality in patients above 65 years 39. Malone et al 40, in a study that assessed the differences in treatment after acute myocardial infarction according to age, reported that the use of angioten ...
Device Closure for Ventricular Septal Defect After Myocardial Infarction
Device Closure for Ventricular Septal Defect After Myocardial Infarction

... be pulled through the defect. The diameter at this volume is then measured ex vivo and used to guide device size selection. Alternatively, the stop-flow technique may be used when a longer compliant balloon is placed across the defect and measured at the volume at which shunting is eliminated on Dop ...
$doc.title

... d. The  onset  of  ischemic  symptoms  could  still  occur  several  hours  after  cocaine  ingestion,  at  a  time  when   blood  concentrations  are  low  or  undetectable   e. Cocaine  metabolites  rise  in  concentrations  several  hours ...
Value of Apical Circumferential Strain in the Early Post
Value of Apical Circumferential Strain in the Early Post

... morbidity and mortality. The aim of the present study was to examine whether LV deformational and torsional parameters can predict LV remodeling in patients with AMI. Methods: Forty-two patients (age 57 ± 14 years) presenting with an anterior ST-elevation AMI and treated with primary percutaneous tr ...
4528-Review
4528-Review

... but also to know the extent of perfusion defect zone after coronary occlusion, which is also known as the area at risk (AAR) of myocardium[1]. Since the AAR includes both infracted/nonviable and viable/salvageable myocardium, detection of the AAR may provide an accurate index in clinical practice an ...
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Drug-eluting stent



A drug-eluting stent (DES) is a peripheral or coronary stent (a scaffold) placed into narrowed, diseased peripheral or coronary arteries that slowly releases a drug to block cell proliferation. This prevents fibrosis that, together with clots (thrombi), could otherwise block the stented artery, a process called restenosis. The stent is usually placed within the peripheral or coronary artery by an interventional cardiologist or interventional radiologist during an angioplasty procedure.Drug-eluting stents in current clinical use were approved by the FDA after clinical trials showed they were statistically superior to bare-metal stents for the treatment of native coronary artery narrowings, having lower rates of major adverse cardiac events (usually defined as a composite clinical endpoint of death + myocardial infarction + repeat intervention because of restenosis). The first drug-eluting stents to be approved in Europe and the U.S. were coated with paclitaxel or an mTOR inhibitor, such as sirolimus.
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