4528-Review
... but also to know the extent of perfusion defect zone after coronary occlusion, which is also known as the area at risk (AAR) of myocardium[1]. Since the AAR includes both infracted/nonviable and viable/salvageable myocardium, detection of the AAR may provide an accurate index in clinical practice an ...
... but also to know the extent of perfusion defect zone after coronary occlusion, which is also known as the area at risk (AAR) of myocardium[1]. Since the AAR includes both infracted/nonviable and viable/salvageable myocardium, detection of the AAR may provide an accurate index in clinical practice an ...
Integrative Physiology
... Figure 2. Histological analysis of dKO hearts. A, Longitudinal section of a dKO heart stained with trichrome (healthy myocardium, red; fibrotic tissue, blue). Arrow and B/C box indicate fibrotic lesions in the left ventricular outflow tract area; arrowheads, right ventricular wall lesions. *Left ven ...
... Figure 2. Histological analysis of dKO hearts. A, Longitudinal section of a dKO heart stained with trichrome (healthy myocardium, red; fibrotic tissue, blue). Arrow and B/C box indicate fibrotic lesions in the left ventricular outflow tract area; arrowheads, right ventricular wall lesions. *Left ven ...
Overview of pleiotropic effects of platelet P2Y12receptor inhibitors
... found in a wide variety of tissues including certain subregions of the brain (11), vascular smooth muscle cells (12, 13), leukocytes (14), macrophages (15), microglial (16) and dendritic cells (17), thus increasing the amount of potential effectors for P2Y12 blockers (1) (▶ Figure 2). Furthermore, t ...
... found in a wide variety of tissues including certain subregions of the brain (11), vascular smooth muscle cells (12, 13), leukocytes (14), macrophages (15), microglial (16) and dendritic cells (17), thus increasing the amount of potential effectors for P2Y12 blockers (1) (▶ Figure 2). Furthermore, t ...
Remote Ischemic Conditioning for the Reduction of Ischemia
... As the RIC protocol had to be initiated before reperfusion, randomization had to occur prior to PCI and before a definitive decision could be made as to whether the patient had met specific inclusion criteria. In addition, many of the enrolled patients did complete follow-up with the imaging data re ...
... As the RIC protocol had to be initiated before reperfusion, randomization had to occur prior to PCI and before a definitive decision could be made as to whether the patient had met specific inclusion criteria. In addition, many of the enrolled patients did complete follow-up with the imaging data re ...
Expert position paper on the use of proton pump inhibitors in
... In an open-label, four-period crossover study, the effects of lansoprazole on the pharmacokinetics and pharmacodynamics of prasugrel and clopidogrel were assessed in healthy subjects given single doses of prasugrel 60 mg and clopidogrel 300 mg with and without concurrent lansoprazole 30 mg q.d. Lans ...
... In an open-label, four-period crossover study, the effects of lansoprazole on the pharmacokinetics and pharmacodynamics of prasugrel and clopidogrel were assessed in healthy subjects given single doses of prasugrel 60 mg and clopidogrel 300 mg with and without concurrent lansoprazole 30 mg q.d. Lans ...
Canadian Cardiovascular Society Guidelines on Perioperative
... complications), identified topics and working groups, searched the literature, developed the summary of findings and GRADE quality assessment tables, voted on the recommendations, and wrote the guidelines. The secondary panel reviewed the guidelines manuscript and made suggested edits and comments, wh ...
... complications), identified topics and working groups, searched the literature, developed the summary of findings and GRADE quality assessment tables, voted on the recommendations, and wrote the guidelines. The secondary panel reviewed the guidelines manuscript and made suggested edits and comments, wh ...
Anti-Inflammatory Strategies for Ventricular Remodeling Following ST-Segment Elevation Acute Myocardial Infarction
... Mechanisms of action for the different anti-inflammatory treatments. (Upper left) Glucocorticoids bind a receptor (GR) in the cytosol that homodimerizes and translocates to the nucleus to exert anti-inflammatory effects, whereas other nongenomic effects are related to endothelial nitric oxide synthase ...
... Mechanisms of action for the different anti-inflammatory treatments. (Upper left) Glucocorticoids bind a receptor (GR) in the cytosol that homodimerizes and translocates to the nucleus to exert anti-inflammatory effects, whereas other nongenomic effects are related to endothelial nitric oxide synthase ...
Role of ticagrelor in the treatment of coronary artery disease
... Ischemic complications of coronary arterial disease are mainly attributed to plateletrich thrombus generation at the site of vascular injury [1] . Adenosine diphosphate (ADP) is an important secondary agonist released from platelet dense granules in response to multiple stimuli such as thromboxane A ...
... Ischemic complications of coronary arterial disease are mainly attributed to plateletrich thrombus generation at the site of vascular injury [1] . Adenosine diphosphate (ADP) is an important secondary agonist released from platelet dense granules in response to multiple stimuli such as thromboxane A ...
Fondaparinux for the Treatment of Superficial
... pulmonary embolism at presentation — are at risk for subsequent symptomatic venous thromboembolic complications.1-7 In a large, prospective, observational study, the 3-month risk of such complications was 8.3%, with a 3.3% risk of deep-vein thrombosis or pulmonary embolism.8 The treatment of this di ...
... pulmonary embolism at presentation — are at risk for subsequent symptomatic venous thromboembolic complications.1-7 In a large, prospective, observational study, the 3-month risk of such complications was 8.3%, with a 3.3% risk of deep-vein thrombosis or pulmonary embolism.8 The treatment of this di ...
The Safety of COX
... A proposal by Merck to reintroduce Vioxx to the market would require a supplemental new drug application. Such an application would be reviewed with consideration of the risk to benefit balance of the proposed indications and populations for use, warnings in the label, and all relevant data. We expe ...
... A proposal by Merck to reintroduce Vioxx to the market would require a supplemental new drug application. Such an application would be reviewed with consideration of the risk to benefit balance of the proposed indications and populations for use, warnings in the label, and all relevant data. We expe ...
Clinical Update - Arquivos Brasileiros de Cardiologia
... where EF is visualized must be delimited by the operator, including slices 1 cm above the emergence of the left main coronary artery to the cardiac apex. The pericardium must be outlined manually by the operator at each cross-section, thus determining the area of interest. There may be difficulties ...
... where EF is visualized must be delimited by the operator, including slices 1 cm above the emergence of the left main coronary artery to the cardiac apex. The pericardium must be outlined manually by the operator at each cross-section, thus determining the area of interest. There may be difficulties ...
Print - Circulation Research
... Downloaded from http://circres.ahajournals.org/ by guest on June 12, 2017 ...
... Downloaded from http://circres.ahajournals.org/ by guest on June 12, 2017 ...
Aalborg Universitet Detection of coronary artery disease
... Coronary artery disease (CAD) is a major health problem and accounts for approximately 20% of all death in Europe. Despite of a wide range of diagnostic tests diagnostic challenges still remains. Up to 59 % of patients submitted to the invasive and costly Coronary angiography doesn’t suffer from CAD ...
... Coronary artery disease (CAD) is a major health problem and accounts for approximately 20% of all death in Europe. Despite of a wide range of diagnostic tests diagnostic challenges still remains. Up to 59 % of patients submitted to the invasive and costly Coronary angiography doesn’t suffer from CAD ...
Quality Improvement Guidelines for Angiography, Angioplasty
... Diagnosis and Treatment of Renal Artery Stenosis in Adults (revised in 2009). The SIR document herein has been adapted and abbreviated to meet the format and content requirements of SIR Quality Improvement document template and does not include sections pertaining to credentialing, documentation, or ...
... Diagnosis and Treatment of Renal Artery Stenosis in Adults (revised in 2009). The SIR document herein has been adapted and abbreviated to meet the format and content requirements of SIR Quality Improvement document template and does not include sections pertaining to credentialing, documentation, or ...
Aalborg Universitet Detection of coronary artery disease with an electronic stethoscope
... Coronary artery disease (CAD) is a major health problem and accounts for approximately 20% of all death in Europe. Despite of a wide range of diagnostic tests diagnostic challenges still remains. Up to 59 % of patients submitted to the invasive and costly Coronary angiography doesn’t suffer from CAD ...
... Coronary artery disease (CAD) is a major health problem and accounts for approximately 20% of all death in Europe. Despite of a wide range of diagnostic tests diagnostic challenges still remains. Up to 59 % of patients submitted to the invasive and costly Coronary angiography doesn’t suffer from CAD ...
Persistent left superior vena cava with an absent right superior vena
... venogram was implemented with 2 venous lines placed into both forearms. This allows the exclusion of all venous connections that may not be detected with only 1 side contrast injection. A persistent LSVC may be also suspected during other tests: for example, by a chest X-ray which reveals a widened ...
... venogram was implemented with 2 venous lines placed into both forearms. This allows the exclusion of all venous connections that may not be detected with only 1 side contrast injection. A persistent LSVC may be also suspected during other tests: for example, by a chest X-ray which reveals a widened ...
Myocardial Infarction Analysis Based on ST
... Wilkins et al.34 divided this sum by the number of leads with phases 1A, 1B, 2A and 2B to evaluate the anatomic extension involved in the AMI, hence producing the Anderson-Wilkins ECG acuteness score. That score is restricted to the leads with positive T wave and ST-segment elevation28,33. This scor ...
... Wilkins et al.34 divided this sum by the number of leads with phases 1A, 1B, 2A and 2B to evaluate the anatomic extension involved in the AMI, hence producing the Anderson-Wilkins ECG acuteness score. That score is restricted to the leads with positive T wave and ST-segment elevation28,33. This scor ...
Atrial Coronary Arteries: Anatomy And Atrial Perfusion
... Anatomically, Kugel described that the posterior portion of the interatrial septum divides anteriorly forming a “Y” shape where the stem represents the interatrial septum posteriorly and wings to form the anterior walls of both atria. Kugel’s artery lies along the anterior atrial walls and travels i ...
... Anatomically, Kugel described that the posterior portion of the interatrial septum divides anteriorly forming a “Y” shape where the stem represents the interatrial septum posteriorly and wings to form the anterior walls of both atria. Kugel’s artery lies along the anterior atrial walls and travels i ...
Management of Intra-Aortic Balloon Pumps
... In the United States, it is estimated that IABP augmentation is used in approximately 30% of complex cardiovascular procedures.38 However, there is much debate over the evidence behind many of the clinical settings and indications for which IABP augmentation is used. The Benchmark Registry demonstra ...
... In the United States, it is estimated that IABP augmentation is used in approximately 30% of complex cardiovascular procedures.38 However, there is much debate over the evidence behind many of the clinical settings and indications for which IABP augmentation is used. The Benchmark Registry demonstra ...
A STUDY OF DIRECT CORONARY SURGERY
... curative therapy available at present. The demand for adequate surgical measures to be applied to such patients is becoming more urgent. Whereas the indirect method for the revascularization of the ischemic myocardium, implantation of the internal mammary artery, originally described by Vineberg, is ...
... curative therapy available at present. The demand for adequate surgical measures to be applied to such patients is becoming more urgent. Whereas the indirect method for the revascularization of the ischemic myocardium, implantation of the internal mammary artery, originally described by Vineberg, is ...
NEJM -- An International Ra
... ensured by auditing 10 percent of the data forms. The audits involved at least one visit to each enrolling site, during which cross-checks between the case-report forms and the source medical records were made. In addition to this verification, similar audits were performed for all patients who had ...
... ensured by auditing 10 percent of the data forms. The audits involved at least one visit to each enrolling site, during which cross-checks between the case-report forms and the source medical records were made. In addition to this verification, similar audits were performed for all patients who had ...
Magnitude of myocardial dysfunction is greater in painful than in
... exercise echocardiography over other forms of stress, particularly pharmacologic, is that it combines excellent physiologic cardiovascular stress, physician familiarity with ECG changes and symptoms with cross-sectional echocardiography to detect ischemia-induced wall motion abnormalities. Its diagn ...
... exercise echocardiography over other forms of stress, particularly pharmacologic, is that it combines excellent physiologic cardiovascular stress, physician familiarity with ECG changes and symptoms with cross-sectional echocardiography to detect ischemia-induced wall motion abnormalities. Its diagn ...
Drug-eluting stent
A drug-eluting stent (DES) is a peripheral or coronary stent (a scaffold) placed into narrowed, diseased peripheral or coronary arteries that slowly releases a drug to block cell proliferation. This prevents fibrosis that, together with clots (thrombi), could otherwise block the stented artery, a process called restenosis. The stent is usually placed within the peripheral or coronary artery by an interventional cardiologist or interventional radiologist during an angioplasty procedure.Drug-eluting stents in current clinical use were approved by the FDA after clinical trials showed they were statistically superior to bare-metal stents for the treatment of native coronary artery narrowings, having lower rates of major adverse cardiac events (usually defined as a composite clinical endpoint of death + myocardial infarction + repeat intervention because of restenosis). The first drug-eluting stents to be approved in Europe and the U.S. were coated with paclitaxel or an mTOR inhibitor, such as sirolimus.