
pdf file - John Innes Centre
... formation between GlnK and AmtB was obtained by purification of the intact complex from the membrane fraction of E. coli cells that had been subjected to a prior ammonium shock (15). A series of subsequent studies in other bacteria supported the proposition that this interaction is conserved among p ...
... formation between GlnK and AmtB was obtained by purification of the intact complex from the membrane fraction of E. coli cells that had been subjected to a prior ammonium shock (15). A series of subsequent studies in other bacteria supported the proposition that this interaction is conserved among p ...
Anterior PAR proteins function during cytokinesis and
... from each particular assay was quantified (Total n). These embryos were first divided into groups based on gross embryonic phenotypes observed: wild type (hatched) and unhatched embryos. Unhatched embryos are embryos that did not arrest at the one-cell stage but arrested later in development. Of the ...
... from each particular assay was quantified (Total n). These embryos were first divided into groups based on gross embryonic phenotypes observed: wild type (hatched) and unhatched embryos. Unhatched embryos are embryos that did not arrest at the one-cell stage but arrested later in development. Of the ...
CHARACTERIZATION OF THE ROLE OF PSEUDOMONAS
... effector HopAF1, a type III effector that is present in eleven of the nineteen sequenced strains of P. syringae and other plant pathogens. Although the presence of HopAF1 in multiple strains of P. syringae suggests that it plays an important role in virulence, no function has yet been associated wit ...
... effector HopAF1, a type III effector that is present in eleven of the nineteen sequenced strains of P. syringae and other plant pathogens. Although the presence of HopAF1 in multiple strains of P. syringae suggests that it plays an important role in virulence, no function has yet been associated wit ...
Ageing and the aggregating proteoglycans of
... the post-translational enzymes responsible for glycosylation and sulphation, and (c) proteolytic modification of the intact proteoglycan after its secretion into the extracellular matrix. It is likely that all the above mechanisms are acting during the normal ageing process, though the evidence for ...
... the post-translational enzymes responsible for glycosylation and sulphation, and (c) proteolytic modification of the intact proteoglycan after its secretion into the extracellular matrix. It is likely that all the above mechanisms are acting during the normal ageing process, though the evidence for ...
Type III secretion: The bacteria-eukaryotic cell
... but it does not insert in membranes of infected erythrocytes [22]. These observations suggest a model in which the hydrophilic translocator, acting as an extracellular chaperone, helps the hydrophobic translocators to integrate in the eukaryotic plasma membrane and to form there a pore (Fig. 2). Thi ...
... but it does not insert in membranes of infected erythrocytes [22]. These observations suggest a model in which the hydrophilic translocator, acting as an extracellular chaperone, helps the hydrophobic translocators to integrate in the eukaryotic plasma membrane and to form there a pore (Fig. 2). Thi ...
Unit 14 – Biomolecules
... The primary structure of protein refers to the specific sequence in which various amino acids are present in it, i.e., the sequence of linkages between amino acids in a polypeptide chain. The ...
... The primary structure of protein refers to the specific sequence in which various amino acids are present in it, i.e., the sequence of linkages between amino acids in a polypeptide chain. The ...
Sarcomeric Protein Mutations in Dilated Cardiomyopathy DCM
... • Desmin is a cytoskeletal protein which forms muscle specific intermediate filaments, connecting the nuclear and plasma membranes of cardiomyocytes. • Desmin is involved in the regulation of intermediate filament organization and structure during the cell cycle, through the post-translational modif ...
... • Desmin is a cytoskeletal protein which forms muscle specific intermediate filaments, connecting the nuclear and plasma membranes of cardiomyocytes. • Desmin is involved in the regulation of intermediate filament organization and structure during the cell cycle, through the post-translational modif ...
The Other Lives of Ribosomal Proteins - PDXScholar
... the cytoplasm through nuclear envelope budding (NEB). Similarly, RPs were initially thought to be involved only in ribosome assembly, but some RPs are now considered to have regulatory functions outside their function in the ribosome. Their roles in cellular functions range from regulation of mammal ...
... the cytoplasm through nuclear envelope budding (NEB). Similarly, RPs were initially thought to be involved only in ribosome assembly, but some RPs are now considered to have regulatory functions outside their function in the ribosome. Their roles in cellular functions range from regulation of mammal ...
Full Article - PDF - Journal of Biotech Research
... Folic acids are essential cofactors for synthesis of DNA, RNA, membrane lipids, methionine metabolism and neurotransmitter synthesis. P. falciparum is capable of synthesizing folate de novo or obtaining it through salvage, whereas humans can only obtain folate from their diet, making the folate path ...
... Folic acids are essential cofactors for synthesis of DNA, RNA, membrane lipids, methionine metabolism and neurotransmitter synthesis. P. falciparum is capable of synthesizing folate de novo or obtaining it through salvage, whereas humans can only obtain folate from their diet, making the folate path ...
Translation - e
... EF-G controls the translocation process: movement of the Psite tRNA to the E site; movement of the A-site tRNA to the Psite and mRNA movement by three nucleotides to expose the next codon. The initial steps of translocation are coupled to the peptidyl transferase reaction. EF-G recognizes the peptid ...
... EF-G controls the translocation process: movement of the Psite tRNA to the E site; movement of the A-site tRNA to the Psite and mRNA movement by three nucleotides to expose the next codon. The initial steps of translocation are coupled to the peptidyl transferase reaction. EF-G recognizes the peptid ...
The Plant Cell - Semantic Scholar
... Among the different proteases in chloroplasts, FtsH is a major one in thylakoid membranes. It is an ATP-dependent metalloprotease that belongs to a AAA (ATPase associated with diverse cellular activities) protease subfamily of the large AAA protein family (Patel and Latterich, 1998; Neuwald et al. ...
... Among the different proteases in chloroplasts, FtsH is a major one in thylakoid membranes. It is an ATP-dependent metalloprotease that belongs to a AAA (ATPase associated with diverse cellular activities) protease subfamily of the large AAA protein family (Patel and Latterich, 1998; Neuwald et al. ...
EVOLUTIONARILY RELATED INSERTION PATHWAYS OF
... protein is believed to cross by interaction with the membrane lipids. This mechanism may be used by some multispanning membrane proteins for translocating small domains to the trans side. ...
... protein is believed to cross by interaction with the membrane lipids. This mechanism may be used by some multispanning membrane proteins for translocating small domains to the trans side. ...
Characterization of the Cytosolic Proteins Involved in the Amoeboid
... Two of the proteins had reciprocal effects on fiber growth: p38 increased fiber growth rate and p16 decreased fiber growth rate. The effects of both p38 and p16 were concentration-dependent and antagonistic. Since the rate-enhancement by p38 was not potentiated by MSP, another cytosolic protein is i ...
... Two of the proteins had reciprocal effects on fiber growth: p38 increased fiber growth rate and p16 decreased fiber growth rate. The effects of both p38 and p16 were concentration-dependent and antagonistic. Since the rate-enhancement by p38 was not potentiated by MSP, another cytosolic protein is i ...
universidad complutense de madrid - E-Prints Complutense
... localization of an onion orthologue, AcNMCP1. Finally, we compare the features of NMCPs with that of lamins and discuss the possibility that they play some of the functions of lamins in the plant cell. A search on Phytozome v8 database revealed that all land plants express at least two NMCP proteins ...
... localization of an onion orthologue, AcNMCP1. Finally, we compare the features of NMCPs with that of lamins and discuss the possibility that they play some of the functions of lamins in the plant cell. A search on Phytozome v8 database revealed that all land plants express at least two NMCP proteins ...
A Per-ARNT-Sim-Like Sensor Domain Uniquely
... Ye, 1999; Ratcliffe et al., 2000, Otsuga et al., 2001). Loss of REV function leads to failure to produce axillary meristems and functional floral meristems. It also leads to alteration of vascular patterning within the stem. When rev mutations are combined with loss-of-function mutations in the PHB ...
... Ye, 1999; Ratcliffe et al., 2000, Otsuga et al., 2001). Loss of REV function leads to failure to produce axillary meristems and functional floral meristems. It also leads to alteration of vascular patterning within the stem. When rev mutations are combined with loss-of-function mutations in the PHB ...
Cytosolic Hsp70 and co-chaperones constitute a novel system for
... Then, an effect of the ssa2 mutation on tRNA import was assessed under the conditions of nutrient starvation. Wild-type, ssa1Δ, and ssa2Δ cells cultured in the YPD medium were transferred to the amino acid-starvation medium SD+Ura, Ade (SD), and the localization of tRNA-ProUGG and tRNA-iMet was anal ...
... Then, an effect of the ssa2 mutation on tRNA import was assessed under the conditions of nutrient starvation. Wild-type, ssa1Δ, and ssa2Δ cells cultured in the YPD medium were transferred to the amino acid-starvation medium SD+Ura, Ade (SD), and the localization of tRNA-ProUGG and tRNA-iMet was anal ...
Diapositiva 1 - ASCRS/ASOA 2008
... right and left eyes of a single subject. All the normal electrophoretic bands are clearly more intense (increased evaporation?) ...
... right and left eyes of a single subject. All the normal electrophoretic bands are clearly more intense (increased evaporation?) ...
Hedgehog signal transduction: recent findings Kent
... The Hh family of molecules are secreted proteins that undergo several post-translational modifications to gain full activity. Hh molecules undergo a maturation process in which they autocatalytically cleave, generating an N-terminal polypeptide (Hh-Np) containing all the signaling functions, and a C ...
... The Hh family of molecules are secreted proteins that undergo several post-translational modifications to gain full activity. Hh molecules undergo a maturation process in which they autocatalytically cleave, generating an N-terminal polypeptide (Hh-Np) containing all the signaling functions, and a C ...
A differential response element for the homeotics at the Antennapedia P1 promoter of Drosophila. Proc. Natl. Acad. Sci. USA 91, 7420-7424 .pdf
... could be due to use of different regulatory elements (targeting differences), or from differences in the functional consequences of the proteins at the same regulatory elements (activity differences). Although their similar intrinsic DNAbinding properties argue for the importance of activity differe ...
... could be due to use of different regulatory elements (targeting differences), or from differences in the functional consequences of the proteins at the same regulatory elements (activity differences). Although their similar intrinsic DNAbinding properties argue for the importance of activity differe ...
A Calcium-Regulated Gatekeeper in Phloem Sieve Tubes
... have somewhat limited distribution. Proteinaceous P-type plastids were observed in just 64 of 382 dicot families studied by Behnke (1991a); the majority of families contained starch-filled S-type plastids. Calcium is an important component of many signal transduction pathways, and calcium regulation ...
... have somewhat limited distribution. Proteinaceous P-type plastids were observed in just 64 of 382 dicot families studied by Behnke (1991a); the majority of families contained starch-filled S-type plastids. Calcium is an important component of many signal transduction pathways, and calcium regulation ...
NMR Spectroscopy - www2.mpip
... Wüthrich first solution structure of a small protein (BPTI) from NOE derived distance restraints 3D NMR + 13C, 15N isotope labeling of recombinant proteins (resolution) pulsed field gradients (artifact suppression) new long range structural parameters: - residual dipolar couplings from partial align ...
... Wüthrich first solution structure of a small protein (BPTI) from NOE derived distance restraints 3D NMR + 13C, 15N isotope labeling of recombinant proteins (resolution) pulsed field gradients (artifact suppression) new long range structural parameters: - residual dipolar couplings from partial align ...
Comparative Analysis of ,Multiple Protein
... homologous (ancestrally related) features,while the identity) it is very difficultto deduce which residues of other attempts to align functionally or spatially equiv- a pr0tei.nare necessary for function or structure, on the alent features of protein a family. Whilethere is consid- basis of multiple ...
... homologous (ancestrally related) features,while the identity) it is very difficultto deduce which residues of other attempts to align functionally or spatially equiv- a pr0tei.nare necessary for function or structure, on the alent features of protein a family. Whilethere is consid- basis of multiple ...
Supplemental figure legends13092010HM
... Particles were initially centred against a rotationally average total sum and classified using multivariate statistical analysis (MSA) as implemented in IMAGIC-5 (van Heel et al, 1996). Classes were inspected and selected (based on the visual match between the class average and the individual parti ...
... Particles were initially centred against a rotationally average total sum and classified using multivariate statistical analysis (MSA) as implemented in IMAGIC-5 (van Heel et al, 1996). Classes were inspected and selected (based on the visual match between the class average and the individual parti ...
Essays41 Chap03 - Essays in Biochemistry
... easily cover this distance by diffusion, and by use of these substrates it has been found that archaebacterial proteasomes preferentially hydrolyse peptide bonds at the C-terminal side of large hydrophobic amino-acid residues, thus exhibiting chymotrypsin-like specificity. However, within protein su ...
... easily cover this distance by diffusion, and by use of these substrates it has been found that archaebacterial proteasomes preferentially hydrolyse peptide bonds at the C-terminal side of large hydrophobic amino-acid residues, thus exhibiting chymotrypsin-like specificity. However, within protein su ...
Traffic between the plant endoplasmic reticulum and Golgi
... compartments [30], or precursors of the prevacuolar compartment. Microscopy supports the existence of a TGNlike structure at the plant Golgi [31,32]. Earlier studies have also pointed to the existence of subdomains of the TGN [33]. The golgin AtGRIP is thought to localize at the transGolgi, although ...
... compartments [30], or precursors of the prevacuolar compartment. Microscopy supports the existence of a TGNlike structure at the plant Golgi [31,32]. Earlier studies have also pointed to the existence of subdomains of the TGN [33]. The golgin AtGRIP is thought to localize at the transGolgi, although ...
Intrinsically disordered proteins

An intrinsically disordered protein (IDP) is a protein that lacks a fixed or ordered three-dimensional structure. IDPs cover a spectrum of states from fully unstructured to partially structured and include random coils, (pre-)molten globules, and large multi-domain proteins connected by flexible linkers. They constitute one of the main types of protein (alongside globular, fibrous and membrane proteins).The discovery of IDPs has challenged the traditional protein structure paradigm, that protein function depends on a fixed three-dimensional structure. This dogma has been challenged over the last decades by increasing evidence from various branches of structural biology, suggesting that protein dynamics may be highly relevant for such systems. Despite their lack of stable structure, IDPs are a very large and functionally important class of proteins. In some cases, IDPs can adopt a fixed three-dimensional structure after binding to other macromolecules.