M06: Genome sequences supplementary material File
... means they may look different but they are related because they share similar biochemical properties. ...
... means they may look different but they are related because they share similar biochemical properties. ...
Slide 1
... White pox disease lesion on A. palmata at Looe Key Reef, FL, August 1998. (The square pin (1.61 cm2) was for calibration of image tracing software) ...
... White pox disease lesion on A. palmata at Looe Key Reef, FL, August 1998. (The square pin (1.61 cm2) was for calibration of image tracing software) ...
AtCHIP functions as an E3 ubiquitin ligase of protein phosphatase
... and the Arabidopsis UBC8, UBC9 and UBC10 are classified in the same family as UBC4/5 E2 enzymes of yeast (Bachmair et al., 2001; Girod et al., 1993; Seufert and Jentsch, 1990). There are at least three dozen E2 genes in the Arabidopsis genome (Bachmair et al., 2001), and three of them encode protein ...
... and the Arabidopsis UBC8, UBC9 and UBC10 are classified in the same family as UBC4/5 E2 enzymes of yeast (Bachmair et al., 2001; Girod et al., 1993; Seufert and Jentsch, 1990). There are at least three dozen E2 genes in the Arabidopsis genome (Bachmair et al., 2001), and three of them encode protein ...
In Depth Analysis of the Spectra Unassigned by Database Search
... shows that the software identified several PSMs with the same mutation on that site, indicating this is likely correct. The peptide-spectrum annotation is examined by clicking on one of these peptides (Figure 4); and indeed, the mutated peptide is supported by highly confident peaks. A literature se ...
... shows that the software identified several PSMs with the same mutation on that site, indicating this is likely correct. The peptide-spectrum annotation is examined by clicking on one of these peptides (Figure 4); and indeed, the mutated peptide is supported by highly confident peaks. A literature se ...
From Molecular Machines to Hierarchical Modeling
... This project is a combined experimental and computational effort emphasizing developing, prototyping, and applying new computational tools and methods to ellucidate the biochemical mechanisms of the carbon sequestration of Synechococcus Sp., an abundant marine cyanobacteria known to play an importan ...
... This project is a combined experimental and computational effort emphasizing developing, prototyping, and applying new computational tools and methods to ellucidate the biochemical mechanisms of the carbon sequestration of Synechococcus Sp., an abundant marine cyanobacteria known to play an importan ...
Like-acetylglucosaminyltransferase (LARGE)
... highly conserved among vertebrates and is located just beyond the DGN (Fig. S3), the entity that is recognized by LARGE. Moreover, this interaction between the DGN and LARGE is necessary for functional glycosylation of α-dystroglycan. Notably, DGN is cleaved by a furin-like protease during the postt ...
... highly conserved among vertebrates and is located just beyond the DGN (Fig. S3), the entity that is recognized by LARGE. Moreover, this interaction between the DGN and LARGE is necessary for functional glycosylation of α-dystroglycan. Notably, DGN is cleaved by a furin-like protease during the postt ...
Molecular Components of the Bacterial Cytoskeleton
... settled when the three-dimensional protein structure of FtsZ was reported and FtsZ was shown to have the same two-domain fold as tubulin, with a conserved GTPase binding pocket in the N-terminal domain, and the residues responsible for GTP hydrolysis residing on a flexible loop (called the T7 loop) ...
... settled when the three-dimensional protein structure of FtsZ was reported and FtsZ was shown to have the same two-domain fold as tubulin, with a conserved GTPase binding pocket in the N-terminal domain, and the residues responsible for GTP hydrolysis residing on a flexible loop (called the T7 loop) ...
Theoretical studies of Membrane Proteins
... Membrane proteins are a large and important class of proteins. They are responsible for several of the key functions in a living cell, e.g. transport of nutrients and ions, cell-cell signaling, and cell-cell adhesion. Despite their importance it has not been possible to study their structure and org ...
... Membrane proteins are a large and important class of proteins. They are responsible for several of the key functions in a living cell, e.g. transport of nutrients and ions, cell-cell signaling, and cell-cell adhesion. Despite their importance it has not been possible to study their structure and org ...
Guard Cells Possess a Calcium-Dependent
... stomata and stimulates closure of open stomata in isolated epidermal peels of Commelina communis (De Silva et al., 1985; Schwartz, 1985; Schwartz et al., 1988); such Ca21 application is known to increase cytosolic Ca21 levels (Gilroy et al., 1991). In addition, a variety of stimuli such as ABA, CO2, ...
... stomata and stimulates closure of open stomata in isolated epidermal peels of Commelina communis (De Silva et al., 1985; Schwartz, 1985; Schwartz et al., 1988); such Ca21 application is known to increase cytosolic Ca21 levels (Gilroy et al., 1991). In addition, a variety of stimuli such as ABA, CO2, ...
Membrane-coating lattice scaffolds in the nuclear pore
... regulates all traffic between the cytoplasm and the nucleus. It is a large protein assembly composed of multiple copies of ∼30 nucleoporins (nups). Structural studies of the NPC have been limited by its considerable size and complexity. Progress toward understanding the structure of this nanomachine ...
... regulates all traffic between the cytoplasm and the nucleus. It is a large protein assembly composed of multiple copies of ∼30 nucleoporins (nups). Structural studies of the NPC have been limited by its considerable size and complexity. Progress toward understanding the structure of this nanomachine ...
Amyloid Deposits: Protection Against Toxic Protein
... It has been hypothesized that Aβ accumulation is the primary cause of pathogenesis in AD, yet there is a weak correlation between Aβ plaque density and the severity of dementia11. For example, brain samples of aged patients without clinical dementia can display abundant Aβ plaques11. To some extent ...
... It has been hypothesized that Aβ accumulation is the primary cause of pathogenesis in AD, yet there is a weak correlation between Aβ plaque density and the severity of dementia11. For example, brain samples of aged patients without clinical dementia can display abundant Aβ plaques11. To some extent ...
Interactions of Virus Proteins Within the Host Cell
... Viruses are ancient parasites that predate all three domains of life: Eukarya, Bacteria and Archaea. Viruses can be found in every habitat where life exists and they are a strong driving force behind the evolution of organisms. In particular, viruses that infect bacteria have been isolated from the ...
... Viruses are ancient parasites that predate all three domains of life: Eukarya, Bacteria and Archaea. Viruses can be found in every habitat where life exists and they are a strong driving force behind the evolution of organisms. In particular, viruses that infect bacteria have been isolated from the ...
The TACC proteins: TACC-ling microtubule dynamics and
... Figure 2. Localization and function of TACC proteins at the centrosome. (a) Localization of different members of the TACC family of proteins. Immunofluorescence images of a one-cell stage C.elegans embryo (courtesy of P. Gönczy, Swiss Institute for Experimental Cancer Research, Ch. Des Boveresses 1 ...
... Figure 2. Localization and function of TACC proteins at the centrosome. (a) Localization of different members of the TACC family of proteins. Immunofluorescence images of a one-cell stage C.elegans embryo (courtesy of P. Gönczy, Swiss Institute for Experimental Cancer Research, Ch. Des Boveresses 1 ...
Functional studies of the BTB domain in the Drosophila GAGA and
... genes that encode BTB domain-containing proteins with roles in transcription regulation (25,26). trl encodes GAGA protein (26). GAGA was first identified as a factor that stimulates in vitro transcription of the Drosophila engrailed and Ultrabithorax promoters (27,28). Subsequent studies have shown ...
... genes that encode BTB domain-containing proteins with roles in transcription regulation (25,26). trl encodes GAGA protein (26). GAGA was first identified as a factor that stimulates in vitro transcription of the Drosophila engrailed and Ultrabithorax promoters (27,28). Subsequent studies have shown ...
Aspects of growth factor signal transduction in the cell cytoplasm
... phorylating other phosphotyrosines that were suppressing signalling potentials of other peptides; Src tyrosine kinases were cited as an example. Superti-Furga et al. (1993) propose, on the basis of experimental induction of c-Src in yeast, that its SH3 domain is required for stabilising the interact ...
... phorylating other phosphotyrosines that were suppressing signalling potentials of other peptides; Src tyrosine kinases were cited as an example. Superti-Furga et al. (1993) propose, on the basis of experimental induction of c-Src in yeast, that its SH3 domain is required for stabilising the interact ...
Sample pages 1 PDF
... its function has not been demonstrated. The Arabidopsis genome encodes orthologs of animal clathrin-mediated vesicular trafficking proteins (Boehm and Bonifacino 2001). Adaptin orthologs in Arabidopsis identified by propeptide sequence alignments (Sanderfoot and Raikhel 2002; Boehm and Bonifacino 20 ...
... its function has not been demonstrated. The Arabidopsis genome encodes orthologs of animal clathrin-mediated vesicular trafficking proteins (Boehm and Bonifacino 2001). Adaptin orthologs in Arabidopsis identified by propeptide sequence alignments (Sanderfoot and Raikhel 2002; Boehm and Bonifacino 20 ...
A Series of Ubiquitin Binding Factors Connects CDC48/p97 to
... 3A–3C). This effect was dose dependent and mediated by the CDC48 protein but apparently not by its cofactors (Figure 3D). It was specific for CDC48, as even a large excess of BSA did not cause a similar reduction (Figure 3A). CDC48 selectively inhibited the formation of very long E4-catalyzed chains ...
... 3A–3C). This effect was dose dependent and mediated by the CDC48 protein but apparently not by its cofactors (Figure 3D). It was specific for CDC48, as even a large excess of BSA did not cause a similar reduction (Figure 3A). CDC48 selectively inhibited the formation of very long E4-catalyzed chains ...
Nup153 is an M9containing mobile nucleoporin with a novel
... 50–100 different proteins, termed nucleoporins, that assemble in multiple copies to form the complex. Biochemical, genetic and genome sequencing approaches have led to the identification of ~30 yeast nucleoporins or NPCassociated proteins, while about half as many higher eukaryotic nucleoporins have ...
... 50–100 different proteins, termed nucleoporins, that assemble in multiple copies to form the complex. Biochemical, genetic and genome sequencing approaches have led to the identification of ~30 yeast nucleoporins or NPCassociated proteins, while about half as many higher eukaryotic nucleoporins have ...
PowerPoint
... structure rather than sequence and used the resulting sequence alignments as their database from which to gather substitution statistics. In principle, the Rissler or Overington matrices should give more reliable results than either PAM or BLOSUM. However, the comparatively small number of available ...
... structure rather than sequence and used the resulting sequence alignments as their database from which to gather substitution statistics. In principle, the Rissler or Overington matrices should give more reliable results than either PAM or BLOSUM. However, the comparatively small number of available ...
Selenium incorporation using recombinant techniques
... a course, revealing the elemental composition of the sample. ...
... a course, revealing the elemental composition of the sample. ...
Crossing borders to bind proteins—a new concept in protein
... protein ligands if the target protein is involved in protein– protein interactions or from phage display or m-RNA display [22, 23]. Again, the peptides that bind proteins need not bind with high affinities, because polypeptide conjugation enhances binder performance. A binder molecule for the D-dime ...
... protein ligands if the target protein is involved in protein– protein interactions or from phage display or m-RNA display [22, 23]. Again, the peptides that bind proteins need not bind with high affinities, because polypeptide conjugation enhances binder performance. A binder molecule for the D-dime ...
Phloem RNA-binding proteins as potential components of the long
... R-CmPP16-1 was seen to bind both sense and antisense CmPP161 RNA, as well as RCNMV RNA2, but failed to interact with both single-stranded and double-stranded DNA. In this pioneer work, microinjection experiments followed by in situ localization helped determine that CmPP16 is able to interact with p ...
... R-CmPP16-1 was seen to bind both sense and antisense CmPP161 RNA, as well as RCNMV RNA2, but failed to interact with both single-stranded and double-stranded DNA. In this pioneer work, microinjection experiments followed by in situ localization helped determine that CmPP16 is able to interact with p ...
Gene expression (Protein synthesis )
... tRNA molecule. The enzyme peptidyltransferase catalyzes the formation of the peptide bond. ...
... tRNA molecule. The enzyme peptidyltransferase catalyzes the formation of the peptide bond. ...
types of gel - WordPress.com
... TYPES OF GEL 1. Agarose Agarose gels are made from the natural polysaccharide polymers extracted from seaweed. Agarose gels are easily cast and handled compared to other matrices, because the gel setting is a physical rather than chemical change. Samples are also easily recovered. After the experime ...
... TYPES OF GEL 1. Agarose Agarose gels are made from the natural polysaccharide polymers extracted from seaweed. Agarose gels are easily cast and handled compared to other matrices, because the gel setting is a physical rather than chemical change. Samples are also easily recovered. After the experime ...
Intrinsically disordered proteins
An intrinsically disordered protein (IDP) is a protein that lacks a fixed or ordered three-dimensional structure. IDPs cover a spectrum of states from fully unstructured to partially structured and include random coils, (pre-)molten globules, and large multi-domain proteins connected by flexible linkers. They constitute one of the main types of protein (alongside globular, fibrous and membrane proteins).The discovery of IDPs has challenged the traditional protein structure paradigm, that protein function depends on a fixed three-dimensional structure. This dogma has been challenged over the last decades by increasing evidence from various branches of structural biology, suggesting that protein dynamics may be highly relevant for such systems. Despite their lack of stable structure, IDPs are a very large and functionally important class of proteins. In some cases, IDPs can adopt a fixed three-dimensional structure after binding to other macromolecules.