see p. Mov50 - Viktor`s Notes for the Neurosurgery Resident
... sporadic cases >> familial cases (may be inherited in autosomal recessive manner). variety of exogenous factors (toxins, viral infection, hypoxia, irradiation) may lead to cerebellar malformations. in some cases of severe cerebellar malformation, ataxia is surprisingly mild. EPIDEMIOLOGY - r ...
... sporadic cases >> familial cases (may be inherited in autosomal recessive manner). variety of exogenous factors (toxins, viral infection, hypoxia, irradiation) may lead to cerebellar malformations. in some cases of severe cerebellar malformation, ataxia is surprisingly mild. EPIDEMIOLOGY - r ...
Entrainment of the Fetal Circadian Clock by Temperature Cycles
... Circadian rhythms are 24-hour rhythms in behavior, physiology, and biochemistry affec6ng processes from gene expression, to the 6ming of sleep and wakefulness. In the cells of humans, and other animals, circadian rhythms are generated by interac6ons among a few key genes and their protein products. ...
... Circadian rhythms are 24-hour rhythms in behavior, physiology, and biochemistry affec6ng processes from gene expression, to the 6ming of sleep and wakefulness. In the cells of humans, and other animals, circadian rhythms are generated by interac6ons among a few key genes and their protein products. ...
Aberrant Resting-State Functional Connectivity in the
... insula and caudate that differed between adolescent patients and healthy comparison participants. Our findings of insula dysfunction and its association with fatigue severity and pain intensity in adolescent CFS demonstrate an aberration of the salience network which might play a role in CFS pathoph ...
... insula and caudate that differed between adolescent patients and healthy comparison participants. Our findings of insula dysfunction and its association with fatigue severity and pain intensity in adolescent CFS demonstrate an aberration of the salience network which might play a role in CFS pathoph ...
Deshpande_Gopikrishna_200708_phd
... unrelenting motivation and drive to reach higher echelons in my life and I wish to express immense gratitude for that. There are no words that can describe my eternal gratitude to my parents, Dr. Narayana Dutt and Katyayini. The person I am today is because of their selfless and committed efforts to ...
... unrelenting motivation and drive to reach higher echelons in my life and I wish to express immense gratitude for that. There are no words that can describe my eternal gratitude to my parents, Dr. Narayana Dutt and Katyayini. The person I am today is because of their selfless and committed efforts to ...
Candidate Gene Association Mapping of Arabidopsis
... and quantitative genetics of flowering time in A. thaliana, a substantial amount of natural variation in flowering time remains unexplained (Werner et al. 2005a). In recent years, structured association mapping has emerged as a major tool in the search for genes that underlie quantitative trait vari ...
... and quantitative genetics of flowering time in A. thaliana, a substantial amount of natural variation in flowering time remains unexplained (Werner et al. 2005a). In recent years, structured association mapping has emerged as a major tool in the search for genes that underlie quantitative trait vari ...
Galanin in Alzheimer s disease: Neuroinhibitory or neuroprotective?
... mutation exhibit amyloid plaque deposition in the hippocampal stratum lacunosum-moleculare subfield and entorhinal cortex concurrent with the appearance of dystrophic GAL-ir neurites in many of the plaques [60]. Occasional GAL-ir cell bodies were also observed in the hippocampus that were not eviden ...
... mutation exhibit amyloid plaque deposition in the hippocampal stratum lacunosum-moleculare subfield and entorhinal cortex concurrent with the appearance of dystrophic GAL-ir neurites in many of the plaques [60]. Occasional GAL-ir cell bodies were also observed in the hippocampus that were not eviden ...
365 Brainy Fact-A
... --The smallest bone in the human body is the "stapes." This bone, found in the ear, is only --400 to 500 ml of cerebrospinal fluid is 0.25 to 0.33 cm long (0.10 to 0.13 inches) produced each day. and weighs only 1.9 to 4.3 milligrams. ...
... --The smallest bone in the human body is the "stapes." This bone, found in the ear, is only --400 to 500 ml of cerebrospinal fluid is 0.25 to 0.33 cm long (0.10 to 0.13 inches) produced each day. and weighs only 1.9 to 4.3 milligrams. ...
Discharge Rate of Substantia Nigra Pars Reticulata Neurons Is
... dyskinesia is a consequence of long-term anti-dopaminergic treatments (classic neuroleptic drugs) usually targeting mental health illnesses. Its prominent manifestation is usually orofacial (Jenner and Marsden 1987). TS is a disorder characterized by chronic tics, often accompanied by obsessive comp ...
... dyskinesia is a consequence of long-term anti-dopaminergic treatments (classic neuroleptic drugs) usually targeting mental health illnesses. Its prominent manifestation is usually orofacial (Jenner and Marsden 1987). TS is a disorder characterized by chronic tics, often accompanied by obsessive comp ...
20356-46231-3-SP - Scandinavian Journal of Child and
... imaging studies in young patients with BPD have investigated the effect of prior exposure to early life stressors on brain anatomy. While the findings in children, who have experienced childhood maltreatment, were inconsistent with respect to brain differences in prefrontal cortices, reduced corpus ...
... imaging studies in young patients with BPD have investigated the effect of prior exposure to early life stressors on brain anatomy. While the findings in children, who have experienced childhood maltreatment, were inconsistent with respect to brain differences in prefrontal cortices, reduced corpus ...
The Neuropathology of Huntington`s Disease
... hyperkinetic and dyskinetic movements. In HD, the initial symptoms of hyperkinesia and chorea are caused by the initial preferential damage in the indirect GABA/ENK striatopallidal pathway (①) that project from the striatum to the GPe. The loss of striatal neurons that give rise to the indirect path ...
... hyperkinetic and dyskinetic movements. In HD, the initial symptoms of hyperkinesia and chorea are caused by the initial preferential damage in the indirect GABA/ENK striatopallidal pathway (①) that project from the striatum to the GPe. The loss of striatal neurons that give rise to the indirect path ...
Temporal Plasticity Involved in Recovery from Manual Dexterity
... monkey with a small hand-held brush. We defined the digit region of M1 as a 2 mm square of cortical surface centered on the penetration site that satisfied at least one of the following criteria: (1) digit movements were obtained at a current lower than 10 A, or (2) digit movements were obtained wh ...
... monkey with a small hand-held brush. We defined the digit region of M1 as a 2 mm square of cortical surface centered on the penetration site that satisfied at least one of the following criteria: (1) digit movements were obtained at a current lower than 10 A, or (2) digit movements were obtained wh ...
SVPaper110411
... length {Akagi, 2008 #99}. In cell culture, about 10% of LINE-1 insertions delete DNA{Gilbert, 2002 #136;Symer, 2002 #135}, a process that also occurs in mouse genomic DNA{Garvey, 2002 #137}. While this suggests SV formation is recurrent {Egan, 2007 #98}, it is not known to what extent retrotranspos ...
... length {Akagi, 2008 #99}. In cell culture, about 10% of LINE-1 insertions delete DNA{Gilbert, 2002 #136;Symer, 2002 #135}, a process that also occurs in mouse genomic DNA{Garvey, 2002 #137}. While this suggests SV formation is recurrent {Egan, 2007 #98}, it is not known to what extent retrotranspos ...
Glutamate Receptors
... An ascending glutamate pathway starts from the thalamus and innervates pyramidal neurons and is known as the thalamocortical pathway (pathway c in Figure 9-38). This is the return leg of the CSTC loop (see Figures 7-16 to 7-21), namely from thalamus to cortex, and provides not only feedback to the o ...
... An ascending glutamate pathway starts from the thalamus and innervates pyramidal neurons and is known as the thalamocortical pathway (pathway c in Figure 9-38). This is the return leg of the CSTC loop (see Figures 7-16 to 7-21), namely from thalamus to cortex, and provides not only feedback to the o ...
Natural Genetic Variation Can Independently Tune the
... complex response of GAL expression distributions to genetic and environmental perturbations, ...
... complex response of GAL expression distributions to genetic and environmental perturbations, ...
1 Prenatal Nicotine Exposure as a Teratogen in
... In the present study, it was concluded that prenatal nicotine exposure in the second trimester causes an up-regulation in dopaminergic neurological pathways and alters dopamine release levels. The altered dopamine levels make the fetus brain more sensitive to the nicotine, causing the nicotine ex ...
... In the present study, it was concluded that prenatal nicotine exposure in the second trimester causes an up-regulation in dopaminergic neurological pathways and alters dopamine release levels. The altered dopamine levels make the fetus brain more sensitive to the nicotine, causing the nicotine ex ...
PDE5 Exists in Human Neurons and is a Viable Therapeutic Target
... for a variety of neurologic diseases. Although many of these studies have focused on Alzheimer’s disease, the PDE5 literature suggests that PDE5 inhibition may be therapeutic in a variety of neurological disorders (see Discussion). Despite the successes in the animal literature, PDE5 inhibitors have ...
... for a variety of neurologic diseases. Although many of these studies have focused on Alzheimer’s disease, the PDE5 literature suggests that PDE5 inhibition may be therapeutic in a variety of neurological disorders (see Discussion). Despite the successes in the animal literature, PDE5 inhibitors have ...
Neural Basis of Brain Dysfunction Produced by Early Sleep Problems
... Abstract: There is a wealth of evidence that disrupted sleep and circadian rhythms, which are common in modern society even during the early stages of life, have unfavorable effects on brain function. Altered brain function can cause problem behaviors later in life, such as truancy from or dropping ...
... Abstract: There is a wealth of evidence that disrupted sleep and circadian rhythms, which are common in modern society even during the early stages of life, have unfavorable effects on brain function. Altered brain function can cause problem behaviors later in life, such as truancy from or dropping ...
Social stimulation and corticolimbic reactivity in premenstrual dysphoric disorder: a preliminary study
... Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/ ...
... Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/ ...
Comparing functional connectivity via thresholding correlations and
... as a measure of similarity and thresholding correlations simply clusters together all voxels whose similarity exceeds a threshold value. A fourth method, structural equations models (Gonçalves & Hall 2003), attempts to model the connectivity, but this is only feasible for connectivity between a sma ...
... as a measure of similarity and thresholding correlations simply clusters together all voxels whose similarity exceeds a threshold value. A fourth method, structural equations models (Gonçalves & Hall 2003), attempts to model the connectivity, but this is only feasible for connectivity between a sma ...
DEPARTAMENT DE FARMACOLOGIA, DE TERAPÈUTICA I DE TOXICOLOGIA
... showed significantly poorer performance than cannabis users and non drug using controls in a measure of semantic word fluency. When ecstasy users were classified according to lifetime use of ecstasy, the more severe users (more than 100 tablets) showed additional deficits on episodic memory. After t ...
... showed significantly poorer performance than cannabis users and non drug using controls in a measure of semantic word fluency. When ecstasy users were classified according to lifetime use of ecstasy, the more severe users (more than 100 tablets) showed additional deficits on episodic memory. After t ...
Methamphetamine Users in Sustained Abstinence
... methamphetamine-dependent subjects followed longitudinally. Wang et al24 examined glucose metabolism using positron emission tomography and reported normalized thalamic metabolism following protracted abstinence (⬎12 months) relative to reduced metabolism assessed after a shorter abstinence interval ...
... methamphetamine-dependent subjects followed longitudinally. Wang et al24 examined glucose metabolism using positron emission tomography and reported normalized thalamic metabolism following protracted abstinence (⬎12 months) relative to reduced metabolism assessed after a shorter abstinence interval ...
annual report of the erwin l. hahn institute for magnetic resonance
... complementary research excellence representing a worldwide unique research consortium of biomedical research scientists, clinicians and cutting edge metabolic imaging experts in Germany. ICEMED consists of more than 30 leading German diabetes and obesity research teams and research centres. The alli ...
... complementary research excellence representing a worldwide unique research consortium of biomedical research scientists, clinicians and cutting edge metabolic imaging experts in Germany. ICEMED consists of more than 30 leading German diabetes and obesity research teams and research centres. The alli ...
The Drosophila Pox neuro gene: control of male courtship behavior
... and posterior lobes of male genitalia. Three enhancers, two of which overlap, control the development of chemosensory bristles in the labellum, legs and wings, some or all of which are required for the transmission of gustatory signals ...
... and posterior lobes of male genitalia. Three enhancers, two of which overlap, control the development of chemosensory bristles in the labellum, legs and wings, some or all of which are required for the transmission of gustatory signals ...
In Vitro, Ex Vivo and In Vivo Techniques to Study Neuronal Migration
... 3. How to Study Neuronal Migration in the Cerebral Cortex Research on the molecular mechanisms regulating cortical neuronal migration is relevant not only to understand brain development, but also to gain insights into the mechanisms that underlie several neurological disorders. The experimental app ...
... 3. How to Study Neuronal Migration in the Cerebral Cortex Research on the molecular mechanisms regulating cortical neuronal migration is relevant not only to understand brain development, but also to gain insights into the mechanisms that underlie several neurological disorders. The experimental app ...
Rapidly progressive Alzheimer`s disease features
... investigation and prion protein gene sequencing, was concluded to be rapidly progressive Alzheimer’s disease (Chitravas et al., 2011). Data from all of the cases with rapidly progressive Alzheimer’s disease collected independently at prion centres in Germany, Japan, Spain and France have uniformly c ...
... investigation and prion protein gene sequencing, was concluded to be rapidly progressive Alzheimer’s disease (Chitravas et al., 2011). Data from all of the cases with rapidly progressive Alzheimer’s disease collected independently at prion centres in Germany, Japan, Spain and France have uniformly c ...