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Rapid eye movement sleep deprivation induces an increase in
Rapid eye movement sleep deprivation induces an increase in

... sults show that 96 h of REM sleep deprivation in rats induced a significant increase in Achase activity in the medulla oblongata, pons and thalamus, without affecting the enzyme’s activity in the striatum, hippocampus or cerebral cortex. The present data agree with the reported heterogeneous distrib ...
The Development of Neural Synchrony and Large
The Development of Neural Synchrony and Large

... (figure 1) in a recent study by our group.11 In adult participants, perceptual integration of Mooney faces was accompanied by prominent increases in gamma-band oscillations over parietal electrodes as well as by theta activity over frontal regions. In addition, phase synchrony of induced oscillation ...
Retinotopic Organization and Functional Subdivisions of the Human
Retinotopic Organization and Functional Subdivisions of the Human

... thereby evoking waves of activation in neurons through whose receptive fields they passed. Each region of the stimulated visual field was exposed to a flickering checkerboard pattern during one-half of the stimulus period and the neutral gray background during the other half. The stimulus waveform w ...
(addl. 3)
(addl. 3)

... be “plastic”: the strength of the excitatory or inhibitory connection must change with learning, and neurons must also be able to create new synapses and hence new connections during the learning process. Research on the mechanisms by which neurons learn, make and break connections, and possess memo ...
Challenges for Brain Emulation
Challenges for Brain Emulation

... be “plastic”: the strength of the excitatory or inhibitory connection must change with learning, and neurons must also be able to create new synapses and hence new connections during the learning process. Research on the mechanisms by which neurons learn, make and break connections, and possess memo ...
Structural Abnormalities of the Central Auditory Pathway in Infants
Structural Abnormalities of the Central Auditory Pathway in Infants

... Corp., WI) with an eight-channel pediatric head coil employed as the MR signal receiver to improve the signal-to-noise ratio. Axial three-dimensional T1-weighted images of the subjects were acquired using a fast spoiled gradient-echo sequence (Ax 3D-FSPGR). The standard structural scanning protocol ...
Thomas A. Woolsey
Thomas A. Woolsey

... teach students to make accurate observations from specimens. This skill enables students to generate and retain mental conceptualizations of complex three-dimensional (3D) structures in the body. In part, this was to prepare students to interpret observations that could be made only at the surfaces ...
Cellular scaling rules for the brain of afrotherians
Cellular scaling rules for the brain of afrotherians

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Neural Mechanisms of Subclinical Depressive
Neural Mechanisms of Subclinical Depressive

... cingulate and insular cortex hyperactivation while individuals with MDD down-regulated their emotional responses to sad images. Finally, Kanske and colleagues [12] reported anterior cingulate and lateral orbitofrontal cortex hyperactivation during emotion regulation in individuals with remitted MDD ...
The Dual Track theory of Moral Decision-Making: A
The Dual Track theory of Moral Decision-Making: A

... can perform multiple roles and be involved in a variety most theories are unfalsifiable in practice. That’s abof different processes. When this is the case, reverse surd. So we should hold fast to the independence of inferences are invalid: the presence of activation is not evidence. a reliable indi ...
Nonlinear brain dynamics as macroscopic manifestation of
Nonlinear brain dynamics as macroscopic manifestation of

... of resynchronization during a phase transition over an area of cortex. The delays are measurable as brief but distance-dependent phase lags at the various frequencies of oscillation (Freeman, 2004b). However, the length of most axons in cortex is a small fraction of observed distances of long-range ...
Local Field Potential in the Visual System
Local Field Potential in the Visual System

... a signal that provides useful information about the local processing that occurs in the cortical volume near the electrode tip. In part, this resurgent interest stems from studies that have linked hemodynamic signals, including the functional magnetic resonance imaging (fMRI) signal that is extensiv ...
Preview as PDF - Pearson Higher Education
Preview as PDF - Pearson Higher Education

... CHAPTER 2 ...
The role of ventral premotor cortex in action execution and action
The role of ventral premotor cortex in action execution and action

... portion of the inferior frontal cortex, mainly in area 44 of Brodmann. According to our own data, there seems to be a homology between Brodmann area 44 in humans and the monkey area F5. The non-language related motor functions of Broca’s region comprise complex hand movements, associative sensorimot ...
Insights into decision making using choice probability
Insights into decision making using choice probability

... the second question includes a tacit assumption that CP originates from feedforward mechanisms. Recent work on CP calls this assumption into question. Therefore, we also ask, 3) what is the origin of CP?; does it result from feedforward pooling of neuronal activity or from feedback mechanisms such a ...
CHAPTER 3 Neuroscience and Behavior
CHAPTER 3 Neuroscience and Behavior

... ballet routine, or Derek Jeter swing at a baseball, you may have marveled at the complexity—and wondrous abilities—of the human body. But even the most everyday tasks, such as picking up a pencil, writing, and speaking, depend on a sophisticated sequence of events in the body that is itself truly im ...
The History of the EEG
The History of the EEG

... • Fast Fourier Transform seperates spontaneous EEG signal to component frequencies and amplitudes • Restriction: high frequency resolution demands long (in the range of seconds) analysis windows ...
292(1):94-106
292(1):94-106

... structure is intimately connected to normal brain function, as abnormalities in brain structure during development are correlated with a wide range of neurodevelopmental disorders (Kurokawa et al., 2000; Gilmore et al., 2001; Hardan et al., 2001; Rehn and Rees, 2005; Nopoulos et al., 2007). Brain mo ...
Full-Text PDF
Full-Text PDF

... from Schlaug and colleagues [13,14] found no pre-existing differences in CC size in 5–7 year old children about to begin musical training (n = 50) compared with a matched group of children not intending to take music lessons (n = 25), and no differences in the first group of children re-scanned afte ...
article in press - Department of Physiology, Development and
article in press - Department of Physiology, Development and

... sounds, with the former unambiguously more speech-like. We used the Bradley – Terry – Luce technique (David, 1988) which converts paired-comparison data into a relative perceptual scale—in this case a scale of Fspeechlikeness_. This technique requires that the stimulus set includes a reasonable dive ...
Functional imaging of human auditory cortex
Functional imaging of human auditory cortex

... (a) Meta-analysis of 10 fMRI studies (see text) of frequency tuning in human auditory cortex showing cortical-surface regions responsive to high frequencies (red) and low frequencies (blue). HG, Heschl’s gyrus (anterior). (b) Average mirror-symmetric tontopic organization from data analyzed directly ...
Abstracts for each slide presentation are available here
Abstracts for each slide presentation are available here

... (~1mM) and high degree of spectral overlap with amino acids and other brain metabolites, some form of spectral editing is needed for unambiguous detection. Furthermore, because of known tissue (white, gray matter) variation of GABA and its possible regional variation between the thalamus and cortica ...
sample - Testbankonline.Com
sample - Testbankonline.Com

... answer. Do the same for the global results. If you chose the younger chimeric face as the photo with the younger half-face on the left side of the image more than fifty percent of the time, this provides evidence that you have an asymmetric brain. A similar judgment can be made when using the global ...
trans - RUF International
trans - RUF International

... as internal. The loop may be initiated by external stimuli but can continue on its own for some time. When the loop has been firing for some time, the total situation may have changed so that the loop cannot be maintained. Neurons can become “tired” so that the loop amplification gradually drops bel ...
Spike sorting: the overlapping spikes challenge
Spike sorting: the overlapping spikes challenge

... We refined an overlapping spike separation algorithm published by Lewicki in [6] for the use on multichannel recordings and evaluated the performance on simulated data. Our results indicate that the performance increases with rising number of signal channels especially under conditions with high noi ...
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Functional magnetic resonance imaging



Functional magnetic resonance imaging or functional MRI (fMRI) is a functional neuroimaging procedure using MRI technology that measures brain activity by detecting associated changes in blood flow. This technique relies on the fact that cerebral blood flow and neuronal activation are coupled. When an area of the brain is in use, blood flow to that region also increases.The primary form of fMRI uses the blood-oxygen-level dependent (BOLD) contrast, discovered by Seiji Ogawa. This is a type of specialized brain and body scan used to map neural activity in the brain or spinal cord of humans or other animals by imaging the change in blood flow (hemodynamic response) related to energy use by brain cells. Since the early 1990s, fMRI has come to dominate brain mapping research because it does not require people to undergo shots, surgery, or to ingest substances, or be exposed to radiation, etc. Other methods of obtaining contrast are arterial spin labeling and diffusion MRI.The procedure is similar to MRI but uses the change in magnetization between oxygen-rich and oxygen-poor blood as its basic measure. This measure is frequently corrupted by noise from various sources and hence statistical procedures are used to extract the underlying signal. The resulting brain activation can be presented graphically by color-coding the strength of activation across the brain or the specific region studied. The technique can localize activity to within millimeters but, using standard techniques, no better than within a window of a few seconds.fMRI is used both in the research world, and to a lesser extent, in the clinical world. It can also be combined and complemented with other measures of brain physiology such as EEG and NIRS. Newer methods which improve both spatial and time resolution are being researched, and these largely use biomarkers other than the BOLD signal. Some companies have developed commercial products such as lie detectors based on fMRI techniques, but the research is not believed to be ripe enough for widespread commercialization.
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