ABSTRACT Title of Document:
... populations during the first two weeks posthatch due to increased glucose transporter-3 mRNA abundance, glucose uptake and hexokinase activity. Additionally, some of these metabolic markers were positively correlated with the serum glucose concentration. Glutamine metabolism increased in bursacytes ...
... populations during the first two weeks posthatch due to increased glucose transporter-3 mRNA abundance, glucose uptake and hexokinase activity. Additionally, some of these metabolic markers were positively correlated with the serum glucose concentration. Glutamine metabolism increased in bursacytes ...
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... Moscona (1970) have recently shown that the existence of the proper organization at the cellular level is required for the hormonal induction of glutamine synthetase in the embryonic neural retina. They have also shown that inducibility is irreversibly lost after cell dissociation, as result of meta ...
... Moscona (1970) have recently shown that the existence of the proper organization at the cellular level is required for the hormonal induction of glutamine synthetase in the embryonic neural retina. They have also shown that inducibility is irreversibly lost after cell dissociation, as result of meta ...
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... association of the macromolecules with each other [11] to form multi-protein [12] or protein-DNA complexes [13]. Enzymatic reactions with small molecules are favored [14]. Overall this plays a key role in protein folding [15,16] and conformational changes [17,18]. It is easy to understand the fundam ...
... association of the macromolecules with each other [11] to form multi-protein [12] or protein-DNA complexes [13]. Enzymatic reactions with small molecules are favored [14]. Overall this plays a key role in protein folding [15,16] and conformational changes [17,18]. It is easy to understand the fundam ...
Pyruvate dehydrogenase and the regulation of glucose oxidation in
... oxidation by way of pyruvate-induced activation of the pyruvate dehydrogenase complex [15–19]. The mechanism(s) responsible for low coupling of glucose oxidation to glycolysis in hypertrophied hearts are not yet known. The multi-enzyme pyruvate dehydrogenase complex (PDC) catalyzes the oxidative dec ...
... oxidation by way of pyruvate-induced activation of the pyruvate dehydrogenase complex [15–19]. The mechanism(s) responsible for low coupling of glucose oxidation to glycolysis in hypertrophied hearts are not yet known. The multi-enzyme pyruvate dehydrogenase complex (PDC) catalyzes the oxidative dec ...
Glycophorin C Content of Human Erythrocyte
... and used within 4 days. All other reagents were reagent grade chemicals from standard sources. Immunochemical analyses. The methods for preparation of erythrocyte membranes, sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) and periodic acid Schiff s base (PAS) staining, have been ...
... and used within 4 days. All other reagents were reagent grade chemicals from standard sources. Immunochemical analyses. The methods for preparation of erythrocyte membranes, sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) and periodic acid Schiff s base (PAS) staining, have been ...
Low Catecholamine Concentrations Protect Adult Rat Ventricular
... have beneficial effects on cardiac myocyte survival or promote their apoptotic death. This is the case of angiotensin II, the trophic effects of which are well established (Sadoshima et al., 1995) but which was also recently identified as a potent proapoptotic agent (Kajstura et al., 1997). These ob ...
... have beneficial effects on cardiac myocyte survival or promote their apoptotic death. This is the case of angiotensin II, the trophic effects of which are well established (Sadoshima et al., 1995) but which was also recently identified as a potent proapoptotic agent (Kajstura et al., 1997). These ob ...
Selective kinase inhibitors as tools for neuroscience research
... Selective, small molecule protein kinase inhibitors provide another powerful way of studying kinase function. They have two major advantages. First they will act on the endogenous kinase and do not require transfection of over-expression. Secondly they can be used over short time scales, which circu ...
... Selective, small molecule protein kinase inhibitors provide another powerful way of studying kinase function. They have two major advantages. First they will act on the endogenous kinase and do not require transfection of over-expression. Secondly they can be used over short time scales, which circu ...
Serine Residues 286, 288, and 293 within the CIITA: A
... factor Pho4 (31), can alter their subcellular localization. We previously showed that CIITA is phosphorylated on a variety of different serine residues, including a serine at aa 286 (32). Recently, additional phosphorylation sites have been assigned to the general region between aa 253–321 using del ...
... factor Pho4 (31), can alter their subcellular localization. We previously showed that CIITA is phosphorylated on a variety of different serine residues, including a serine at aa 286 (32). Recently, additional phosphorylation sites have been assigned to the general region between aa 253–321 using del ...
Screening for increased protein thiol oxidation in oxidatively
... ROS. One involves irreversible damage to macromolecules such as DNA, membrane lipids and proteins. A number of analytical techniques have been developed to measure the oxidation products directly (e.g. carbonyl assay for oxidized proteins) or the resultant degradation products (e.g. malondialdehyde ...
... ROS. One involves irreversible damage to macromolecules such as DNA, membrane lipids and proteins. A number of analytical techniques have been developed to measure the oxidation products directly (e.g. carbonyl assay for oxidized proteins) or the resultant degradation products (e.g. malondialdehyde ...
Protein Quality Control as a Strategy for Cellular Regulation
... for a regulatory mechanism that is sufficiently flexible to destroy any cellular protein. Ubiquitination of proteins occurs by the successive action of a cascade of three enzymes (Figure 1). This process is extensively detailed in numerous reviews,1 so a useful summary is described here. The E1 ubiq ...
... for a regulatory mechanism that is sufficiently flexible to destroy any cellular protein. Ubiquitination of proteins occurs by the successive action of a cascade of three enzymes (Figure 1). This process is extensively detailed in numerous reviews,1 so a useful summary is described here. The E1 ubiq ...
Clockwork green—the circadian oscillator in
... form a basic oscillator which in turn passes timing information to downstream components and in this way elicits rhythmicity in their expression or activity (Dunlap 1999). Like the well-described oscillators of mammals, flies or fungi, the circadian oscillator in Arabidopsis is based on interconnect ...
... form a basic oscillator which in turn passes timing information to downstream components and in this way elicits rhythmicity in their expression or activity (Dunlap 1999). Like the well-described oscillators of mammals, flies or fungi, the circadian oscillator in Arabidopsis is based on interconnect ...
Enzyme Mechanisms
... It’s one of two energy-rich products of the conversion of light energy into chemical energy in phototrophs ATP then provides drivers for almost everything else other than redox ...
... It’s one of two energy-rich products of the conversion of light energy into chemical energy in phototrophs ATP then provides drivers for almost everything else other than redox ...
Dateien anzeigen - Universität Düsseldorf
... al. 2013). Furthermore, the bacteria can cause a bacterial rot of pears and apples (De Ley et al. 1984). The occurrence of this chemoorganotrophic bacterium is mainly in sugary, alcoholic and acidic environments like flowers, fruits, beer and wine. The best substrates for growth of Gluconobacter spe ...
... al. 2013). Furthermore, the bacteria can cause a bacterial rot of pears and apples (De Ley et al. 1984). The occurrence of this chemoorganotrophic bacterium is mainly in sugary, alcoholic and acidic environments like flowers, fruits, beer and wine. The best substrates for growth of Gluconobacter spe ...
Proteolytic and other metabolic pathways in lysosomes
... lytic’, ‘nuclease’ and ‘lipolytic’ pathways. The proteolytic and nuclease pathways start with enzymes specialized for action on the inner regions of the intact linear polymers that are their substrates, the endopeptidases and endonucleases, respectively. There are definite sequencesof reactions in t ...
... lytic’, ‘nuclease’ and ‘lipolytic’ pathways. The proteolytic and nuclease pathways start with enzymes specialized for action on the inner regions of the intact linear polymers that are their substrates, the endopeptidases and endonucleases, respectively. There are definite sequencesof reactions in t ...
Influence of Aerobic and Phototrophic Growth
... differed with respect to 6-phosphogluconate (6-PG) dehydratase activity: this could not be detected in R . sphaeroides strain 1760-1, but was easily detected in R. sphaeroides strain ATCC 17023. Rhodopseudomonas sphaeroides strain I 760- I was therefore designated as the 6-PG dehydratase- strain. Ne ...
... differed with respect to 6-phosphogluconate (6-PG) dehydratase activity: this could not be detected in R . sphaeroides strain 1760-1, but was easily detected in R. sphaeroides strain ATCC 17023. Rhodopseudomonas sphaeroides strain I 760- I was therefore designated as the 6-PG dehydratase- strain. Ne ...
Internal Assessment: Fermentation Biology Higher Level
... The world glycolysis (sugar splitting) is thought to have been one of the first biochemical pathways to evolve. It uses oxygen and occurs in the cytosol of the cell. The sugar splitting proceeds efficiently in aerobic or anaerobic environments. Glycolysis is the metabolic pathway that is common to a ...
... The world glycolysis (sugar splitting) is thought to have been one of the first biochemical pathways to evolve. It uses oxygen and occurs in the cytosol of the cell. The sugar splitting proceeds efficiently in aerobic or anaerobic environments. Glycolysis is the metabolic pathway that is common to a ...
Influence of Aerobic and Phototrophic Growth
... differed with respect to 6-phosphogluconate (6-PG) dehydratase activity: this could not be detected in R . sphaeroides strain 1760-1, but was easily detected in R. sphaeroides strain ATCC 17023. Rhodopseudomonas sphaeroides strain I 760- I was therefore designated as the 6-PG dehydratase- strain. Ne ...
... differed with respect to 6-phosphogluconate (6-PG) dehydratase activity: this could not be detected in R . sphaeroides strain 1760-1, but was easily detected in R. sphaeroides strain ATCC 17023. Rhodopseudomonas sphaeroides strain I 760- I was therefore designated as the 6-PG dehydratase- strain. Ne ...
University of Groningen Metabolic adaptations in models of
... of this area of research our insight into the mechanisms of miRNA action is expected to significantly increase within the coming years. In summary, many signals have been implicated in zonation of protein expression alongside the portocentral axis. In this respect, the Wnt/β-catenin signaling and it ...
... of this area of research our insight into the mechanisms of miRNA action is expected to significantly increase within the coming years. In summary, many signals have been implicated in zonation of protein expression alongside the portocentral axis. In this respect, the Wnt/β-catenin signaling and it ...
Pyridoxine Pyridoxal Pyridoxamine
... PMP & PNP are oxidized by a FMNFMN-dependent oxidase to form PLP. The forms of vitamin B6 found in food are converted to active forms in the liver. Zinc, riboflavin, and niacin are necessary for this process. Fasting and reducing diets usually deplete the vitamin B6 supply unless it is supplemented. ...
... PMP & PNP are oxidized by a FMNFMN-dependent oxidase to form PLP. The forms of vitamin B6 found in food are converted to active forms in the liver. Zinc, riboflavin, and niacin are necessary for this process. Fasting and reducing diets usually deplete the vitamin B6 supply unless it is supplemented. ...
- BioMedSearch
... CO2 assimilation rates were detected. E. coli PEPS was introduced into potato (a C3 plant) in attempts to introduce an operating C4 photosynthetic pathway under the belief that the bacterial enzyme was not regulated [14]. The regulation of E. coli PEPS by AMP, ADP, oxaloacetate, a-ketoglutarate, mal ...
... CO2 assimilation rates were detected. E. coli PEPS was introduced into potato (a C3 plant) in attempts to introduce an operating C4 photosynthetic pathway under the belief that the bacterial enzyme was not regulated [14]. The regulation of E. coli PEPS by AMP, ADP, oxaloacetate, a-ketoglutarate, mal ...
Aminoacyl-tRNA synthetase complexes: beyond translation
... Although aminoacyl-tRNA synthetases (ARSs) are housekeeping enzymes essential for protein synthesis, they can play non-catalytic roles in diverse biological processes. Some ARSs are capable of forming complexes with each other and additional proteins. This characteristic is most pronounced in mammal ...
... Although aminoacyl-tRNA synthetases (ARSs) are housekeeping enzymes essential for protein synthesis, they can play non-catalytic roles in diverse biological processes. Some ARSs are capable of forming complexes with each other and additional proteins. This characteristic is most pronounced in mammal ...
Functional analysis of the human CDC5L complex
... antibody and the protein revealed using ECL (Amersham). Lanes 1 and 2 are duplicates containing supernatants of mock immunodepletions using pre-immune IgG. Lane 3 contains the supernatant from antiCDC5L antibody immunodepleted nuclear extract and lane 4 is similar to lane 3 except that the antibody ...
... antibody and the protein revealed using ECL (Amersham). Lanes 1 and 2 are duplicates containing supernatants of mock immunodepletions using pre-immune IgG. Lane 3 contains the supernatant from antiCDC5L antibody immunodepleted nuclear extract and lane 4 is similar to lane 3 except that the antibody ...
Absorption, hepatic metabolism and mammary
... Table 2. Range of digestibility of nutrients in ileum and total tract of sows fed low-fiber, high-fiber and highfiber................................................................................................................................................................... 8 Table 3. Differen ...
... Table 2. Range of digestibility of nutrients in ileum and total tract of sows fed low-fiber, high-fiber and highfiber................................................................................................................................................................... 8 Table 3. Differen ...
Surprising variety in energy metabolism within Trypanosomatidae
... substrates used in energy metabolism are not completely oxidised, but instead fermentation products such as acetate and succinate are excreted. However, in this case the electron transport chain uses oxygen as final electron acceptor. Depending on the composition of the electron-transport chain this ...
... substrates used in energy metabolism are not completely oxidised, but instead fermentation products such as acetate and succinate are excreted. However, in this case the electron transport chain uses oxygen as final electron acceptor. Depending on the composition of the electron-transport chain this ...
PDF Datastream - Brown Digital Repository
... using either the GeLC or gel-assisted methodologies........................................................50 Figure 2.12: Venn diagrams illustrating the common and uniquely identified proteins between our studies and Dr. Phadke’s work................................................................. ...
... using either the GeLC or gel-assisted methodologies........................................................50 Figure 2.12: Venn diagrams illustrating the common and uniquely identified proteins between our studies and Dr. Phadke’s work................................................................. ...
Phosphorylation
Phosphorylation is the addition of a phosphate (PO43−) group to a protein or other organic molecule. Phosphorylation and its counterpart, dephosphorylation, turn many protein enzymes on and off, thereby altering their function and activity. Protein phosphorylation is one type of post-translational modification.Protein phosphorylation in particular plays a significant role in a wide range of cellular processes. Its prominent role in biochemistry is the subject of a very large body of research (as of March 2015, the Medline database returns over 240,000 articles on the subject, largely on protein phosphorylation).