Lessons on longevity from budding yeast
... able to retain most of the age-associated damage3,4. In the chronological model, by contrast, damage accumulates over time within a nondividing cell until a threshold is reached beyond which the cell is no longer able to re-enter the cell cycle (Fig. 1). Despite these differences, there are some int ...
... able to retain most of the age-associated damage3,4. In the chronological model, by contrast, damage accumulates over time within a nondividing cell until a threshold is reached beyond which the cell is no longer able to re-enter the cell cycle (Fig. 1). Despite these differences, there are some int ...
LPS- or Pseudomonas aeruginosa- mediated activation of
... (Manders, Verbeek & Aten, 1993). Four independent experiments were performed in triplicates for each combination of PUFA supplementation and stimulation of cells. ...
... (Manders, Verbeek & Aten, 1993). Four independent experiments were performed in triplicates for each combination of PUFA supplementation and stimulation of cells. ...
Steel Factor Induces Serine Phosphorylation of
... Tyrosine phosphorylation of Stat family proteins in factordependent cell lines. Tyrosine phosphorylation of Stat family proteins, presumably by Jak family tyrosine kinases, has been shown to be essential for their DNA binding and transcriptional activation.' We first examined the effect of various h ...
... Tyrosine phosphorylation of Stat family proteins in factordependent cell lines. Tyrosine phosphorylation of Stat family proteins, presumably by Jak family tyrosine kinases, has been shown to be essential for their DNA binding and transcriptional activation.' We first examined the effect of various h ...
Cell adhesion and cell mechanics during zebrafish
... achievement of evolution. After fertilization, a series of cell divisions gives rise to a vast number of cells which subsequently have to share specialized tasks and build complex structures such as eyes, heart or brain (see Fig. 1.1). But how can cells that originate from a single ancestor control ...
... achievement of evolution. After fertilization, a series of cell divisions gives rise to a vast number of cells which subsequently have to share specialized tasks and build complex structures such as eyes, heart or brain (see Fig. 1.1). But how can cells that originate from a single ancestor control ...
A painful TR(i)P to lysosomes
... membrane trafficking of TRPA1 lysosomes is not or differentially regulated by general trafficking cues (Fig. 1). No autophagic defects or lysosomal dysfunction have been reported for TRPA1 KO mice. A provocative speculation is that peripherally localized TRPA1 lysosomes are selectively connected wi ...
... membrane trafficking of TRPA1 lysosomes is not or differentially regulated by general trafficking cues (Fig. 1). No autophagic defects or lysosomal dysfunction have been reported for TRPA1 KO mice. A provocative speculation is that peripherally localized TRPA1 lysosomes are selectively connected wi ...
the 5 kingdmcard 5 - Henrico County Public Schools
... The difference between vertebrates and invertebrates is that vertebrates have backbones, and invertebrates do not. SOL 5.5 ...
... The difference between vertebrates and invertebrates is that vertebrates have backbones, and invertebrates do not. SOL 5.5 ...
Ann Rev of Physiol, v 63, pp. 847-869
... and Neuromuscular Synapses The homeostatic control of neuronal or muscle function implies that the summed strength of all synaptic inputs should remain within certain bounds. According to this hypothesis, increasing the number of synaptic contacts to a single target should result in reduced synaptic ...
... and Neuromuscular Synapses The homeostatic control of neuronal or muscle function implies that the summed strength of all synaptic inputs should remain within certain bounds. According to this hypothesis, increasing the number of synaptic contacts to a single target should result in reduced synaptic ...
Evaluating hypotheses for the origin of eukaryotes
... emerge from three cells, a fusion followed by endosymbiosis. This particular scenario was suggested by Zillig and colleagues,(57) though the term ‘fusion’ is now used widely but imprecisely. However, we restrict usage of the term to cell fusion, as indicated in model i. Model ii, top right panel: en ...
... emerge from three cells, a fusion followed by endosymbiosis. This particular scenario was suggested by Zillig and colleagues,(57) though the term ‘fusion’ is now used widely but imprecisely. However, we restrict usage of the term to cell fusion, as indicated in model i. Model ii, top right panel: en ...
Influence of Bacillus subtilis Cell Walls and EDTA on Calcite
... 4.14-5.75) because the buffer capacity of this solution is negligible but increases drastically following the dissolution of calcite. The pH increased rapidly during the first 24 h of reaction until it reached a plateau value, between 4.6 and 6.5, which differed according to the nature and concentra ...
... 4.14-5.75) because the buffer capacity of this solution is negligible but increases drastically following the dissolution of calcite. The pH increased rapidly during the first 24 h of reaction until it reached a plateau value, between 4.6 and 6.5, which differed according to the nature and concentra ...
A painful TR(i)P to lysosomes
... membrane trafficking of TRPA1 lysosomes is not or differentially regulated by general trafficking cues (Fig. 1). No autophagic defects or lysosomal dysfunction have been reported for TRPA1 KO mice. A provocative speculation is that peripherally localized TRPA1 lysosomes are selectively connected wi ...
... membrane trafficking of TRPA1 lysosomes is not or differentially regulated by general trafficking cues (Fig. 1). No autophagic defects or lysosomal dysfunction have been reported for TRPA1 KO mice. A provocative speculation is that peripherally localized TRPA1 lysosomes are selectively connected wi ...
Monopolar spindle attachment of sister chromatids is ensured by two
... chromosomes. Through this study, we show that the monopolar attachment of sister chromatids is established by two distinct mechanisms: one is independent of homologous chromosomes while the other is dependent on the homologous chromosomes. We provide evidence that the co-operation of these two mecha ...
... chromosomes. Through this study, we show that the monopolar attachment of sister chromatids is established by two distinct mechanisms: one is independent of homologous chromosomes while the other is dependent on the homologous chromosomes. We provide evidence that the co-operation of these two mecha ...
A painful TR(i)P to lysosomes
... membrane trafficking of TRPA1 lysosomes is not or differentially regulated by general trafficking cues (Fig. 1). No autophagic defects or lysosomal dysfunction have been reported for TRPA1 KO mice. A provocative speculation is that peripherally localized TRPA1 lysosomes are selectively connected wi ...
... membrane trafficking of TRPA1 lysosomes is not or differentially regulated by general trafficking cues (Fig. 1). No autophagic defects or lysosomal dysfunction have been reported for TRPA1 KO mice. A provocative speculation is that peripherally localized TRPA1 lysosomes are selectively connected wi ...
A painful TR(i)P to lysosomes
... membrane trafficking of TRPA1 lysosomes is not or differentially regulated by general trafficking cues (Fig. 1). No autophagic defects or lysosomal dysfunction have been reported for TRPA1 KO mice. A provocative speculation is that peripherally localized TRPA1 lysosomes are selectively connected wi ...
... membrane trafficking of TRPA1 lysosomes is not or differentially regulated by general trafficking cues (Fig. 1). No autophagic defects or lysosomal dysfunction have been reported for TRPA1 KO mice. A provocative speculation is that peripherally localized TRPA1 lysosomes are selectively connected wi ...
Arabidopsis VILLIN4 is involved in root hair growth through
... bundles actin filaments in a Ca2+-independent manner, but also severs actin filaments and bundles when Ca2+ is elevated to micromolar levels (Khurana et al., 2010). Loss of function of AtVLN5 sensitizes actin filaments in pollen grains and tubes to latrunculin B, demonstrating that it is a regulator ...
... bundles actin filaments in a Ca2+-independent manner, but also severs actin filaments and bundles when Ca2+ is elevated to micromolar levels (Khurana et al., 2010). Loss of function of AtVLN5 sensitizes actin filaments in pollen grains and tubes to latrunculin B, demonstrating that it is a regulator ...
Signal Peptide-Selection of cDNA Cloned Directly from the
... sedentary endoparasitic nematodes (Hussey 1989a). In preparasitic nematode juveniles, the two subventral esophageal gland cells are large and packed with secretory granules, whereas the one dorsal esophageal gland cell is relatively small and contains few secretory granules. After host root penetrat ...
... sedentary endoparasitic nematodes (Hussey 1989a). In preparasitic nematode juveniles, the two subventral esophageal gland cells are large and packed with secretory granules, whereas the one dorsal esophageal gland cell is relatively small and contains few secretory granules. After host root penetrat ...
ExamplePoster3 - Bridgewater College
... FACTORS INFLUENCING THE SYNTHESIS OF POLYHYDROXYBUTYRATE DEPOLYMERASE IN STREPTOMYCES SP. 5A Matthew B. Persinger, Matthew Shull, and Stephen F. Baron, Biology Dept., Bridgewater College, Bridgewater, VA 22812 ...
... FACTORS INFLUENCING THE SYNTHESIS OF POLYHYDROXYBUTYRATE DEPOLYMERASE IN STREPTOMYCES SP. 5A Matthew B. Persinger, Matthew Shull, and Stephen F. Baron, Biology Dept., Bridgewater College, Bridgewater, VA 22812 ...
Ro52: Structure and interactions of constructs of RING and B-box
... The ubiquitination process is vital to maintain the protein homeostasis in the cell. With high specificity it regulates degradation of proteins by tagging them with a small protein called ubiquitin. Four proteins are involved to perform the process and in this thesis one of these proteins is studied ...
... The ubiquitination process is vital to maintain the protein homeostasis in the cell. With high specificity it regulates degradation of proteins by tagging them with a small protein called ubiquitin. Four proteins are involved to perform the process and in this thesis one of these proteins is studied ...
PDF
... We are investigating the role of polarity genes in the formation of cellular junctions in the larval epidermis of the zebrafish. In zebrafish larvae, the epidermis is bi-layered, consisting of the outer periderm and the underlying basal epidermis (see Fig. 1A). The basal epidermal cells exhibit thre ...
... We are investigating the role of polarity genes in the formation of cellular junctions in the larval epidermis of the zebrafish. In zebrafish larvae, the epidermis is bi-layered, consisting of the outer periderm and the underlying basal epidermis (see Fig. 1A). The basal epidermal cells exhibit thre ...
Role of Phospholipase D in the cAMP Signal Transduction Pathway
... Activity of Phospholipase D during Fibroblast Contraction of Stressed Collagen Matrices Unlike the modest changes in phospholipase A2 and phospholipase C described above, there appeared to be marked activation of phospholipase D initiated by matrix contraction. This was shown first by analyzing phos ...
... Activity of Phospholipase D during Fibroblast Contraction of Stressed Collagen Matrices Unlike the modest changes in phospholipase A2 and phospholipase C described above, there appeared to be marked activation of phospholipase D initiated by matrix contraction. This was shown first by analyzing phos ...
Synergy and duality in peptide antibiotic mechanisms Dewey G
... Thiostrepton and micrococcin are members of the class of thiazole-containing peptide antibiotics (or thiopeptide antibiotics), which inhibit protein biosynthesis by binding to the 23S rRNA subunit of the ribosome and preventing its proper function [1•–3•]. This family of antibiotics (see Figure 1) i ...
... Thiostrepton and micrococcin are members of the class of thiazole-containing peptide antibiotics (or thiopeptide antibiotics), which inhibit protein biosynthesis by binding to the 23S rRNA subunit of the ribosome and preventing its proper function [1•–3•]. This family of antibiotics (see Figure 1) i ...
the sting bulb gland in myrmecia and nothomyrmecia
... of approximately 20 ~m. The nuclei are also rounded or slightly lobate, and measure 810 ~m in diameter (Figs 4, 5). Each cell is characterized by a presumably short but sinuous end apparatus, which, therefore, may appear more than once in a plane section of a particular cell (Figs 4, 6), or not at a ...
... of approximately 20 ~m. The nuclei are also rounded or slightly lobate, and measure 810 ~m in diameter (Figs 4, 5). Each cell is characterized by a presumably short but sinuous end apparatus, which, therefore, may appear more than once in a plane section of a particular cell (Figs 4, 6), or not at a ...
Holding it all together? Candidate proteins for the plant Golgi matrix
... The structure and function of the plant Golgi The Golgi apparatus in plants plays crucial roles in the glycosylation of proteins and lipids and in the production of polysaccharides for cell wall biosynthesis. Proteins are imported from the endoplasmic reticulum (ER), entering the Golgi apparatus on ...
... The structure and function of the plant Golgi The Golgi apparatus in plants plays crucial roles in the glycosylation of proteins and lipids and in the production of polysaccharides for cell wall biosynthesis. Proteins are imported from the endoplasmic reticulum (ER), entering the Golgi apparatus on ...
Protection of Drosophila chromosome ends through minimal
... germ cells, where telomere protection can be challenged without compromising viability. We show that the exhaustion of HOAP results in a dramatic reduction of other capping proteins at telomeres, including K81 [encoded by ms(3)K81], which is essential for male fertility. Strikingly however, we demon ...
... germ cells, where telomere protection can be challenged without compromising viability. We show that the exhaustion of HOAP results in a dramatic reduction of other capping proteins at telomeres, including K81 [encoded by ms(3)K81], which is essential for male fertility. Strikingly however, we demon ...
Microscopy studies on uncultivated magnetotactic bacteria
... bacteria will accumulate at one edge of the drop and the bacteria are said to have polar magnetotactic behaviour. If the magnetic field lines define only the axis of swimming, changes in the magnetic field direction will cause bacteria only to rotate, not accumulate at the edge of the drop [26]. Thi ...
... bacteria will accumulate at one edge of the drop and the bacteria are said to have polar magnetotactic behaviour. If the magnetic field lines define only the axis of swimming, changes in the magnetic field direction will cause bacteria only to rotate, not accumulate at the edge of the drop [26]. Thi ...
Saccharomyces boulardii Using Intraspecific Protoplast Fusion
... Abstract: Highly efficient bio-therapeutic yeast Saccharomyces boulardii strains, were obtained by intraspecific protoplasts fusion. The selected fusants F1 (S.b.M1 X S.b.M 2) (ad - X lys -) and F2 (S.b.M2 X S.b.M3) (lys -´arg -) and their parents; S.b.M1(ad -), S.b.M2 (lys -) and S.b.M 3 (arg -) as ...
... Abstract: Highly efficient bio-therapeutic yeast Saccharomyces boulardii strains, were obtained by intraspecific protoplasts fusion. The selected fusants F1 (S.b.M1 X S.b.M 2) (ad - X lys -) and F2 (S.b.M2 X S.b.M3) (lys -´arg -) and their parents; S.b.M1(ad -), S.b.M2 (lys -) and S.b.M 3 (arg -) as ...
Cytokinesis
Cytokinesis (cyto- + kinesis) is the process during cell division in which the cytoplasm of a single eukaryotic cell is divided to form two daughter cells. It usually initiates during the early stages of mitosis, and sometimes meiosis, splitting a mitotic cell in two, to ensure that chromosome number is maintained from one generation to the next. After cytokinesis two (daughter) cells will be formed that are exact copies of the (parent) original cell. After cytokinesis, each daughter cell is in the interphase portion of the cell cycle. In animal cells, one notable exception to the normal process of cytokinesis is oogenesis (the creation of an ovum in the ovarian follicle of the ovary), where the ovum takes almost all the cytoplasm and organelles, leaving very little for the resulting polar bodies, which then die. Another form of mitosis without cytokinesis occurs in the liver, yielding multinucleate cells. In plant cells, a dividing structure known as the cell plate forms within the centre of the cytoplasm and a new cell wall forms between the two daughter cells.Cytokinesis is distinguished from the prokaryotic process of binary fission.