Latrunculin A Induced Perturbation of the Actin Cytoskeleton
... Pap1p translocates from the cytoplasm to the nucleus upon LatA treatment Previous studies concerning the role of pap1, imp1, and caf5 in the oxidative stress response (Umeda et al., 2005) suggested a straightforward model to be tested. In this model the Pap1p transcription factor is imported into th ...
... Pap1p translocates from the cytoplasm to the nucleus upon LatA treatment Previous studies concerning the role of pap1, imp1, and caf5 in the oxidative stress response (Umeda et al., 2005) suggested a straightforward model to be tested. In this model the Pap1p transcription factor is imported into th ...
Topical aldose reductase inhibitor for correcting
... the polyol accumulation is not sufficient to cause the osmotic effect, while it may cause a depletion of intracellular myoinositol and a subsequent decrease in the membrane bound Na/K dependent ATPase, resulting in cell swelling and death. Several studies have indicated that even with normal cell de ...
... the polyol accumulation is not sufficient to cause the osmotic effect, while it may cause a depletion of intracellular myoinositol and a subsequent decrease in the membrane bound Na/K dependent ATPase, resulting in cell swelling and death. Several studies have indicated that even with normal cell de ...
Salt-Induced Remodeling of Spatially Restricted
... Although the operation and physiological relevance of endocytosis have been demonstrated unequivocally in plants, the molecular components participating in the process are less well characterized than in animal systems. Simple, well-defined tissue organization makes the Arabidopsis thaliana root an i ...
... Although the operation and physiological relevance of endocytosis have been demonstrated unequivocally in plants, the molecular components participating in the process are less well characterized than in animal systems. Simple, well-defined tissue organization makes the Arabidopsis thaliana root an i ...
Early signaling events that underlie fate decisions of naive CD4 T
... TGF-b-mediated iTreg differentiation (23). Naive CD4+ T cells from Rag1 / OT-II TCR-transgenic mice on a scurfy background, which lack functional Foxp3, still fail to undergo Th17 differentiation under Th17-polarizing conditions if IL-2 is added to the culture (24). STAT5 has been shown to compete w ...
... TGF-b-mediated iTreg differentiation (23). Naive CD4+ T cells from Rag1 / OT-II TCR-transgenic mice on a scurfy background, which lack functional Foxp3, still fail to undergo Th17 differentiation under Th17-polarizing conditions if IL-2 is added to the culture (24). STAT5 has been shown to compete w ...
MLAB 1415-Hematology Keri Brophy
... Pallor Fatigue Cardiac symptoms Gallstones Dark or red urine Splenomegaly ...
... Pallor Fatigue Cardiac symptoms Gallstones Dark or red urine Splenomegaly ...
Tropism of human cytomegalovirus for endothelial cells is
... host-cell range during acute infection in vivo, including epithelial cells, fibroblasts, smooth muscle cells, endothelial cells (EC) and macrophages (Ng Bautista & Sedmak, 1995 ; Roberts et al., 1988, 1989 ; Sinzger et al., 1993, 1995, 1996 ; Wiley & Nelson, 1988). EC and macrophages were suggested ...
... host-cell range during acute infection in vivo, including epithelial cells, fibroblasts, smooth muscle cells, endothelial cells (EC) and macrophages (Ng Bautista & Sedmak, 1995 ; Roberts et al., 1988, 1989 ; Sinzger et al., 1993, 1995, 1996 ; Wiley & Nelson, 1988). EC and macrophages were suggested ...
Partitioning of nutrient transport processes in roots
... electrophysiology than yeast) have failed (Kim et al., 1998; Rubio et al., 2000). Evidence that this transport may be channel-like is suggested by the ability of KUP1 to catalyse high rates of Kq transport at mM concentrations, the sensitivity of the transport to tetraethylammonium (a blocker of Kq ...
... electrophysiology than yeast) have failed (Kim et al., 1998; Rubio et al., 2000). Evidence that this transport may be channel-like is suggested by the ability of KUP1 to catalyse high rates of Kq transport at mM concentrations, the sensitivity of the transport to tetraethylammonium (a blocker of Kq ...
- RichardWheeler.net
... 2.8.1 Important considerations in the preparation of cells for SBFSEM........ 530 2.8.2 Primary fixation of cells from a suspension culture ............................ 532 2.8.3 Postfixation, dehydration, and resin embedding................................. 532 2.8.4 Preparation of blocks for SBFSE ...
... 2.8.1 Important considerations in the preparation of cells for SBFSEM........ 530 2.8.2 Primary fixation of cells from a suspension culture ............................ 532 2.8.3 Postfixation, dehydration, and resin embedding................................. 532 2.8.4 Preparation of blocks for SBFSE ...
lengthened g1 phase indicates differentiation status in
... differentiation, extending the duration of total cell cycle time. The coupling of differentiation and cell cycle changes are intrinsically linked throughout the development of many species. Drosophila melogaster2,3, Xenopus laevis4,5, zebrafish6, mouse7, rat8, and human early embryos9 all demonstrat ...
... differentiation, extending the duration of total cell cycle time. The coupling of differentiation and cell cycle changes are intrinsically linked throughout the development of many species. Drosophila melogaster2,3, Xenopus laevis4,5, zebrafish6, mouse7, rat8, and human early embryos9 all demonstrat ...
Lecture_8
... haploinsufficiency has been gaining in appreciation as an important influence on human disease ...
... haploinsufficiency has been gaining in appreciation as an important influence on human disease ...
Cue-Signal-Response Analysis of TNF-Induced
... were derived and scaled to values from zero (complete inhibition) to one (no inhibitor) for each kinase. When the estimated ERK, JNK, p38, and PI3K activities were cast as a four-dimensional signaling space and a one-dimensional response space of measured levels of apoptosis, the problem was not wel ...
... were derived and scaled to values from zero (complete inhibition) to one (no inhibitor) for each kinase. When the estimated ERK, JNK, p38, and PI3K activities were cast as a four-dimensional signaling space and a one-dimensional response space of measured levels of apoptosis, the problem was not wel ...
Lonza Group Ltd
... Simbiosys Biowares Inc., a start-up company based in Dallas, Texas, USA. “We are happy to acquire the preclinical cell and molecular biology group of Simbiosys Biowares India, as it is aligned with Lonza’s strategy to continue to develop its lifescience platform and to expand its global cell-biology ...
... Simbiosys Biowares Inc., a start-up company based in Dallas, Texas, USA. “We are happy to acquire the preclinical cell and molecular biology group of Simbiosys Biowares India, as it is aligned with Lonza’s strategy to continue to develop its lifescience platform and to expand its global cell-biology ...
Retinal pigment epithelial cells phagocytosis of T lymphocytes
... outer segment (ROS), thereby having an essential role in vision.16 The in vivo importance of ROS phagocytosis is highlighted by the spontaneous degeneration of photoreceptors and blindness of the Royal College of Surgeons rats which results from a defect of such phagocytosis.17 Yet, RPE phagocytosis ...
... outer segment (ROS), thereby having an essential role in vision.16 The in vivo importance of ROS phagocytosis is highlighted by the spontaneous degeneration of photoreceptors and blindness of the Royal College of Surgeons rats which results from a defect of such phagocytosis.17 Yet, RPE phagocytosis ...
Forespore membrane assembly in yeast
... 2001). Psy1 localizes to the plasma membrane of mother cells before completion of meiosis I. Immediately after exit from meiosis I, it suddenly disappears from the plasma membrane. It reappears at the cytoplasmic face of the SPB between meiotic metaphase II and anaphase II (Nakamura et al., 2001). T ...
... 2001). Psy1 localizes to the plasma membrane of mother cells before completion of meiosis I. Immediately after exit from meiosis I, it suddenly disappears from the plasma membrane. It reappears at the cytoplasmic face of the SPB between meiotic metaphase II and anaphase II (Nakamura et al., 2001). T ...
Probes for Multiplexed Detection of GFP
... transport and sorting and more. Moreover, unlike antibodies, these fluorescent probes can be used to investigate organelle structure and activity in live cells with minimal disruption of cellular function ( ). The red-fluorescent organelle stains are particularly useful for demonstrating colocalizat ...
... transport and sorting and more. Moreover, unlike antibodies, these fluorescent probes can be used to investigate organelle structure and activity in live cells with minimal disruption of cellular function ( ). The red-fluorescent organelle stains are particularly useful for demonstrating colocalizat ...
H3K4me3 demethylation by the histone
... the nucleotide sequence of DNA replication origins is not endowed with clearly defined features, and cis-acting genetic elements required for ORC binding and origin activity were not characterized until recently (15). Indeed, a consensus G-quadruplex-forming DNA motif that can predict potential posi ...
... the nucleotide sequence of DNA replication origins is not endowed with clearly defined features, and cis-acting genetic elements required for ORC binding and origin activity were not characterized until recently (15). Indeed, a consensus G-quadruplex-forming DNA motif that can predict potential posi ...
IL-10 transcription is negatively regulated by BAF180, a component
... SNF2-like ATPase subunits, and these ATPases couple the hydrolysis of ATP to changes in chromatin structure. SWI/SNF, Mi2, ISWI, and other ATP-dependent remodeling enzymes are classified into subfamilies based upon homology of the ATPase subunit [4,19,20]. These remodeling enzymes appear to both act ...
... SNF2-like ATPase subunits, and these ATPases couple the hydrolysis of ATP to changes in chromatin structure. SWI/SNF, Mi2, ISWI, and other ATP-dependent remodeling enzymes are classified into subfamilies based upon homology of the ATPase subunit [4,19,20]. These remodeling enzymes appear to both act ...
Distribution of polycyclic aromatic hydrocarbons in
... concentration gradient across plant-cell components and (2) accumulation of PAHs in plant tissues, with the extent related to plant lipid contents [18-21]. However, the factors that influence PAH transfer and distribution in plants as well as their metabolism in cells are not clear. Plant uptake of ...
... concentration gradient across plant-cell components and (2) accumulation of PAHs in plant tissues, with the extent related to plant lipid contents [18-21]. However, the factors that influence PAH transfer and distribution in plants as well as their metabolism in cells are not clear. Plant uptake of ...
Endocytosis unplugged: multiple ways to enter the cell
... clathrin indicated that it is capable of coating vesicles 100-200 nm in diameter. Clathrin functions as a trimer of heterodimers, each unit consisting of one heavy and one light chain forming a triskeleton [44]. These triskelia can assemble into a lattice-like structure around the vesicles. Adaptor ...
... clathrin indicated that it is capable of coating vesicles 100-200 nm in diameter. Clathrin functions as a trimer of heterodimers, each unit consisting of one heavy and one light chain forming a triskeleton [44]. These triskelia can assemble into a lattice-like structure around the vesicles. Adaptor ...
Mitosis
Mitosis is a part of the cell cycle in which chromosomes in a cell nucleus are separated into two identical sets of chromosomes, each in its own nucleus. In general, mitosis (division of the nucleus) is often followed by cytokinesis, which divides the cytoplasm, organelles and cell membrane into two new cells containing roughly equal shares of these cellular components. Mitosis and cytokinesis together define the mitotic (M) phase of an animal cell cycle—the division of the mother cell into two daughter cells, genetically identical to each other and to their parent cell.The process of mitosis is divided into stages corresponding to the completion of one set of activities and the start of the next. These stages are prophase, prometaphase, metaphase, anaphase, and telophase. During mitosis, the chromosomes, which have already duplicated, condense and attach to fibers that pull one copy of each chromosome to opposite sides of the cell. The result is two genetically identical daughter nuclei. The cell may then divide by cytokinesis to produce two daughter cells. Producing three or more daughter cells instead of normal two is a mitotic error called tripolar mitosis or multipolar mitosis (direct cell triplication / multiplication). Other errors during mitosis can induce apoptosis (programmed cell death) or cause mutations. Certain types of cancer can arise from such mutations.Mitosis occurs only in eukaryotic cells and the process varies in different organisms. For example, animals undergo an ""open"" mitosis, where the nuclear envelope breaks down before the chromosomes separate, while fungi undergo a ""closed"" mitosis, where chromosomes divide within an intact cell nucleus. Furthermore, most animal cells undergo a shape change, known as mitotic cell rounding, to adopt a near spherical morphology at the start of mitosis. Prokaryotic cells, which lack a nucleus, divide by a different process called binary fission.