• Study Resource
  • Explore
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Viagra - Pfizer
Viagra - Pfizer

... cardiomyopathy), or those with the rare syndrome of multiple system atrophy manifesting as severely impaired autonomic control of blood pressure. Agents for the treatment of erectile dysfunction should be used with caution in patients with anatomical deformation of the penis (such as angulation, cav ...
PRODUCT INFORMATION ISOPTIN INJECTION SOLUTION
PRODUCT INFORMATION ISOPTIN INJECTION SOLUTION

... in extreme cases there may be complete block with or without subsequent asystole. Occasionally, heart failure may develop or existing heart failure may be exacerbated. The risk of inducing ventricular fibrillation is minute, as Isoptin has no effect on the conduction velocity and refractory period i ...
product information
product information

... glucose-galactose malabsorption should not take this medicine. Weight Gain In the controlled studies, weight gain occurred more frequently in patients treated with LYRICA than in patients treated with placebo. LYRICA associated weight gain was related to dose and length of exposure, but did not appe ...
Piracetam reverses haloperidol-induced - Tubitak Journals
Piracetam reverses haloperidol-induced - Tubitak Journals

... Laboratory Animals (34). Equal groups were used in all experiments, with 6 mice in each group. All drug dosages used in the study were based upon the human dose converted to meet the physical parameters of the rats, as detailed in the Paget and Barnes conversion tables (35). ...
Emtricitabine / rilpivirine / tenofovir disoproxil fumarate
Emtricitabine / rilpivirine / tenofovir disoproxil fumarate

... amino acid substitutions that emerged included: L100I, K101E, V108I, E138K, V179F, Y181C, H221Y, F227C and M230I. In Clinical Studies: Treatment-Naïve Patients Considering all of the available in vitro and in vivo data in treatment-naïve patients the following resistance-associated substitutions, wh ...
Consciousness: Sleep, Dreams, Hypnosis, and Drugs
Consciousness: Sleep, Dreams, Hypnosis, and Drugs

... Why sleep and how sleep works Stages of sleep and dreaming Sleep disorders and normal sleep Why people dream and what they dream about Hypnosis and how it works Physical and psychological dependence on a drug How do stimulant and depressants affect consciousness Dangers of narcotics, hallucinogens a ...
Full Reviews Definition, identification and treatment of resistant
Full Reviews Definition, identification and treatment of resistant

... hypertension despite awareness of the condition. Studies conducted among primary care physicians suggest that many physicians have higher BP thresholds for initiation and modification of drug therapy than the recommended treatment goals, and many are not familiar with the JNC guidelines [19]. Perhaps ...
Mendelian Genetics Chapter 12 Reading Mendellian Genetics
Mendelian Genetics Chapter 12 Reading Mendellian Genetics

... As a young man, Mendel studied to be a priest. Later, he went to the University of Vienna. There, he learned how to study science through experimentation and how to use mathematics to explain natural events. Mendel lived the rest of his life in a monastery, where he taught high school and cared for ...
Novel Psychoactive Substances
Novel Psychoactive Substances

...  Stability ...
National inpatient medication chart 2014 national audit report
National inpatient medication chart 2014 national audit report

... Participation in the NIMC national audit, and review of the results, provides hospitals with evidence to assist verifying their services against accreditation requirements in the National Safety and Quality Health Service (NSQHS) Standard 4: Medication Safety4. This report identifies where specific ...
The Science of Psychology
The Science of Psychology

... Why sleep and how sleep works Stages of sleep and dreaming Sleep disorders and normal sleep Why people dream and what they dream about Hypnosis and how it works Physical and psychological dependence on a drug How do stimulant and depressants affect consciousness Dangers of narcotics, hallucinogens a ...
A Descriptive Study of Adverse Events from
A Descriptive Study of Adverse Events from

... from 2 regional poison centers for human exposures to clenbuterol. Data collected after individual chart review, including review of individual case notes fields, included demographics, substances involved including coingestatants if known, reason for exposure/use of clenbuterol, dose, clinical effe ...
Inhaled phosphodiesterase type 5 inhibitors restore chloride transport in cystic fibrosis mice
Inhaled phosphodiesterase type 5 inhibitors restore chloride transport in cystic fibrosis mice

... male erectile dysfunction. We measured in vivo nasal transepithelial potential difference 1 h after a single inhalation of sildenafil, vardenafil or tadalafil in F508del CF and normal homozygous mice. After nebulisation with the drugs in F508del mice, chloride transport, evaluated by perfusing the n ...
New horizons in pulmonary arterial hypertension therapies
New horizons in pulmonary arterial hypertension therapies

... 6MWD continued to improve with a mean increase in the overall cohort (n5214) of 48¡72 m compared with baseline [39]. Functional class also continued to improve and 68% of the overall cohort were in functional class I/II after 1 year of treatment (versus 38–49% at baseline); 36% and 57% of patients s ...
Constipation - Australian Medicines Handbook
Constipation - Australian Medicines Handbook

... – they believe increased fluid intake may worsen urinary incontinence cost may be a problem, especially if long-term laxative use is needed; not all laxatives are subsidised by the PBS and restrictions may apply to those that are there is no convincing evidence that chronic use of stimulant laxative ...
Suppositories in anal disorders: a review
Suppositories in anal disorders: a review

Core-Shell Type Lipid-Polymer Hybrid Nanoparticles as
Core-Shell Type Lipid-Polymer Hybrid Nanoparticles as

... synthesized with a lipid shell and a core that was made from inorganic materials such as silica, 40 magnetic iron oxide, 41 or organic materials such as polysaccharides, 42 polystyrene, 43 polyelectrolyte capsule, 44 or polymer microgels. 45 Comprehensive reviews by Troutier and Ladaviere 46 and Ric ...
40131
40131

... Clopidogrel patients had an event rate of 6.8% and placebo patients had an event rate of 7.3%. CHARISMA demonstrated no significant benefit long term when clopidogrel is added to aspirin. Rates of severe bleeding were similar but clopidogrel patients experienced significantly higher rates of moderat ...
WELLBUTRIN SR
WELLBUTRIN SR

... placebo-controlled trials in adults with MDD or other psychiatric disorders included a total of 295 short-term trials (median duration of 2 months) of 11 antidepressant drugs in over 77,000 subjects. There was considerable variation in risk of suicidality among drugs, but a tendency toward an incre ...
Ritalin LA - Novartis Pharmaceuticals Corporation
Ritalin LA - Novartis Pharmaceuticals Corporation

... of absorption were unchanged after food relative to the fasting state, although the second peak was approximately 25% lower. The effect of a high fat lunch was not examined. There were no differences in the pharmacokinetics of Ritalin LA when administered with applesauce, compared to administration ...
500ct. 10-325 mg HCb and APAP Tablets[Watson[Base[rev2
500ct. 10-325 mg HCb and APAP Tablets[Watson[Base[rev2

... more than one acetaminophen containing product. The excessive intake of acetaminophen may be intentional to cause self-harm or unintentional as patients attempt to obtain more pain relief or unknowingly take other acetaminophencontaining products. The risk of acute liver failure is higher in individ ...
Zebrafish – an in vivo model for in vivo drug screening
Zebrafish – an in vivo model for in vivo drug screening

... Recently, zebrafish-based assays have been developed for testing toxicity of drug candidates, including acute toxicity (LC50), organ-specific toxicity and developmental toxicity (26, 30). The optical clarity of the zebrafish embryo enables a thorough assessment of drug-induced changes in morphology ...
EXTEMPORANEOUS PREPARATION OF PAEDIATRIC ORAL
EXTEMPORANEOUS PREPARATION OF PAEDIATRIC ORAL

... uniformity of content, selection of safe excipients and stability issues are part of the main challenges faced in the preparation of extemporaneous drug products. The present study examined the chemical stabilities and content uniformities of extemporaneously prepared nifedipine oral dosage forms to ...
Unauthorized Research on Cluster Headache
Unauthorized Research on Cluster Headache

... Prentiss and Morgan reported that one of their experimental subjects experienced a three-day headache following a dose of mescaline, severe enough to be debilitating on the second day (Perrine 2001). Investigations all but ceased when anhalonium was removed from the U.S. Pharma- ...
IN VIVO SATIVA Research Article
IN VIVO SATIVA Research Article

... The preliminary phytochemical screening of methanolic extracts of N. sativa from different germination phases showed the presence of alkaloids, flavonoids, terpenes, saponins, and tannins in our previous study which showed higher content of these metabolites during germination phases [9, 10]. Thus, ...
< 1 ... 91 92 93 94 95 96 97 98 99 ... 1254 >

Pharmacogenomics

Pharmacogenomics (a portmanteau of pharmacology and genomics) is the study of the role of genetics in drug response. It deals with the influence of acquired and inherited genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with drug absorption, distribution, metabolism and elimination, as well as drug receptor target effects. The term pharmacogenomics is often used interchangeably with pharmacogenetics. Although both terms relate to drug response based on genetic influences, pharmacogenetics focuses on single drug-gene interactions, while pharmacogenomics encompasses a more genome-wide association approach, incorporating genomics and epigenetics while dealing with the effects of multiple genes on drug response.Pharmacogenomics aims to develop rational means to optimize drug therapy, with respect to the patients' genotype, to ensure maximum efficacy with minimal adverse effects. Through the utilization of pharmacogenomics, it is hoped that drug treatments can deviate from what is dubbed as the “one-dose-fits-all” approach. It attempts to eliminate the trial-and-error method of prescribing, allowing physicians to take into consideration their patient’s genes, the functionality of these genes, and how this may affect the efficacy of the patient’s current and/or future treatments (and where applicable, provide an explanation for the failure of past treatments). Such approaches promise the advent of ""personalized medicine""; in which drugs and drug combinations are optimized for each individual's unique genetic makeup. Whether used to explain a patient’s response or lack thereof to a treatment, or act as a predictive tool, it hopes to achieve better treatment outcomes, greater efficacy, minimization of the occurrence of drug toxicities and adverse drug reactions (ADRs). For patients who have lack of therapeutic response to a treatment, alternative therapies can be prescribed that would best suit their requirements. In order to provide pharmacogenomic-based recommendations for a given drug, two possible types of input can be used: genotyping or exome or whole genome sequencing. Sequencing provides many more data points, including detection of mutations that prematurely terminate the synthesized protein (early stop codon).
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report