• Study Resource
  • Explore
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Nehru Arts and Science College-TM palayam, Coimbatore 105 III B
Nehru Arts and Science College-TM palayam, Coimbatore 105 III B

... (a) polymer (b) monomer (c) micelle (d) nanoparticle 2. Average number of monomers which from micelle at a time is called (a) aggregation number (b) CMC (c) concentration (d) none 3. The concentration of the monomer at which the micelle form is called (a) aggregation number (b) CMC (c) concentration ...
Antiarrhythmic drug pharmacology
Antiarrhythmic drug pharmacology

... Has little effect on contractility and is one of the best drugs to use in heart failure Shown to improve mortality in nonischemic cardiomyopathy patients at risk of sudden death, possible advantageous after MI Has properties of all four classes (i.e. Na+, K+, Ca2+ channel blocker and noncompetitive ...
Chapter 9
Chapter 9

02 66862244 Fax: 02 66862257 Email: sales@custommedi
02 66862244 Fax: 02 66862257 Email: sales@custommedi

... ignore them. Research indicates this may not be the case in many suffers and research also shows that once eradicated symptoms improve greatly. If found to be present you should treat them to eradicate them from your gut in order to obtain better health. Blastocystis hominis can be extremely resista ...
Human Mass Balance Studies
Human Mass Balance Studies

... profiled using highly selective chromatographic method(s) to separate known and unknown metabolites from the unchanged drug. Next, the unknown metabolites are characterized, while the structure of known metabolites are confirmed. Finally, all radiolabeled peaks (unchanged drug and metabolites) are r ...
anticoagulant
anticoagulant

... • Therefore there is 3-5 day delay between the drug administration and the start of anticoagulant effect. • Transient protein C deficiency can also be induced because protein C and factor VII have the shortest half-lives of the coagulation factors. • Consequently protein C is inactivated whereas th ...
Notes 1 Ch 23 Evolution_Pop
Notes 1 Ch 23 Evolution_Pop

... European groups, scientists found that the allele frequencies became mixed in each population because of movement of individuals. It was also found that this gene flow between European and West African groups is much greater in the Northern U.S. than in the South. ...
Intravenous Droperidol or Olanzapine as an
Intravenous Droperidol or Olanzapine as an

... i.v. droperidol or olanzapine as adjunct to i.v. midazolam is efficacious and safe and provides more rapid sedation for acutely agitated patients in the ED Further studies to compare use of i.v. olanzapine alone with other sedative ...
IJPhS_Mar_Aprl 07.pmd - Indian Journal of Pharmaceutical Sciences
IJPhS_Mar_Aprl 07.pmd - Indian Journal of Pharmaceutical Sciences

... completely absorbed and extensively metabolized to its w without pharmacologically active 10-monohydroxy metabolite, D rapidlyhin the saliva ...
11.1. Introducing Gregor Mendel
11.1. Introducing Gregor Mendel

... • This theory stated that if parents were different, offspring would possess traits intermediate between those of parents. • Found to be incorrect by Mendel!! ...
4#3841 UNIT FOUR Participant Handout
4#3841 UNIT FOUR Participant Handout

... It is important to be familiar with the older medications, due to their more prevalent usage with the indigent and ________ populations. The newer antipsychotic medications are more _________. ...
Pain management
Pain management

... If you have ongoing pain then you will be prescribed a stronger medication such as oxycodone (endone), either 5 or 10 mg, which can be taken 6 hourly. For most painful conditions the worst of the pain settles in a few days. As explained by your doctor, when the need for the stronger medication reduc ...
Casodex drug insert
Casodex drug insert

... either enantiomer of bicalutamide was noted in patients with mild-to-moderate hepatic disease as compared to healthy controls. However, the half-life of the R-enantiomer was increased approximately 76% (5.9 and 10.4 days for normal and impaired patients, respectively) in patients with severe liver d ...
Summary of Product Characteristics
Summary of Product Characteristics

... Deanxit should not be administered during pregnancy unless the expected benefit to the patient outweighs the theoretical risk to the foetus. Due to the risk of neonatal withdrawal symptoms it is recommended that Deanxit treatment is stopped about 14 days before delivery by tapering off the dosage. N ...
Chapter 9
Chapter 9

... - the poppy only as 10 days to manufacture opium Morphine - Frederich Serturner, a German chemist synthesized morphine from opium in 1803 - he called it ‘morphium,’ named for Morpheus, the Greek god of dreams ...
Chapter 13
Chapter 13

... determining the recombination frequency between a gene and an anonymous marker Anonymous markers such as single nucleotide polymorphisms (SNPs) can be detected by molecular techniques. ...
Chapter 27 (Genetic Monitoring) - Laboratory Animal Boards Study
Chapter 27 (Genetic Monitoring) - Laboratory Animal Boards Study

... 23. Transgenic strains do not need to be monitored for loss of copy number because it will not affect strain phenotype. 24. If separate lines are created at F20 with continued in breeding the number of loci differing between the two eventual substrains is estimated to be 117. 25. The observed phenot ...
Simon Zheng - A Critical Review of Natural Language Processing Approaches to Discovering Drug-Drug Interactions from Medical Literatur
Simon Zheng - A Critical Review of Natural Language Processing Approaches to Discovering Drug-Drug Interactions from Medical Literatur

... set to score three times that many randomly chosen drug-gene relationships. Each relationship was scored leaving out knowledge of the relationship during training. In performing this external validation, Pharmspresso found many relationships that do not appear in PharmGKB but had high scores from t ...
Alan Goldhammer, PhD
Alan Goldhammer, PhD

... 12. Footnote on Page 75151 – “This proposed rule continues to describe the specific type of expanded access for treatment use that makes investigational drugs available to large populations as the ‘‘treatment IND’’ or ‘‘treatment protocol.’’ We recognize that it may be confusing to carry over this t ...
Genetic Basis of Continuous Traits
Genetic Basis of Continuous Traits

... population, predict the genotypes, and vice versa. • Explain the genetic basis for the normal distribution of a trait in a population. ...
Opiates and Respiratory Depression - index
Opiates and Respiratory Depression - index

... mg of morphine intravenously every time the patient pushes a button on the end of a cable. To prevent excessive drug administration, the onboard computer ignores further patient demands until a lockout period (usually set for 5–10 minutes) has passed. Recently, the Institute for Safe Medication Prac ...
How can value be measured and valued?
How can value be measured and valued?

... the ‘real‐world’ challenges of national implementation. Through the Program which  adopts a system level “PDSA” (Plan, Do, Study, Act) approach, Singapore pilots a  healthcare innovation in a limited manner, learning what works, what does not work  and what needs to be localized, before deciding on  ...
CRC for Plant-based Management of Dryland Salinity Scoping
CRC for Plant-based Management of Dryland Salinity Scoping

... G5. Do the “at risk” natural species/populations have requirement for protection? Yes – High genetic risk with requirement for protection of natural assets No – High genetic risk in that location ...
What is the most effective treatment for ADHD in children?
What is the most effective treatment for ADHD in children?

... Stimulants and atomoxetine improve symptoms of ADHD quite effectively, making office treatment of ADHD a gratifying experience. Like many other diagnoses, there are numerous medications available to treat ADHD. Becoming familiar with a few and regularly prescribing them makes the treatment of ADHD m ...
Heritability of Continuous Traits
Heritability of Continuous Traits

... population, predict the genotypes, and vice versa. • Explain the genetic basis for the normal distribution of a trait in a population. ...
< 1 ... 915 916 917 918 919 920 921 922 923 ... 1254 >

Pharmacogenomics

Pharmacogenomics (a portmanteau of pharmacology and genomics) is the study of the role of genetics in drug response. It deals with the influence of acquired and inherited genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with drug absorption, distribution, metabolism and elimination, as well as drug receptor target effects. The term pharmacogenomics is often used interchangeably with pharmacogenetics. Although both terms relate to drug response based on genetic influences, pharmacogenetics focuses on single drug-gene interactions, while pharmacogenomics encompasses a more genome-wide association approach, incorporating genomics and epigenetics while dealing with the effects of multiple genes on drug response.Pharmacogenomics aims to develop rational means to optimize drug therapy, with respect to the patients' genotype, to ensure maximum efficacy with minimal adverse effects. Through the utilization of pharmacogenomics, it is hoped that drug treatments can deviate from what is dubbed as the “one-dose-fits-all” approach. It attempts to eliminate the trial-and-error method of prescribing, allowing physicians to take into consideration their patient’s genes, the functionality of these genes, and how this may affect the efficacy of the patient’s current and/or future treatments (and where applicable, provide an explanation for the failure of past treatments). Such approaches promise the advent of ""personalized medicine""; in which drugs and drug combinations are optimized for each individual's unique genetic makeup. Whether used to explain a patient’s response or lack thereof to a treatment, or act as a predictive tool, it hopes to achieve better treatment outcomes, greater efficacy, minimization of the occurrence of drug toxicities and adverse drug reactions (ADRs). For patients who have lack of therapeutic response to a treatment, alternative therapies can be prescribed that would best suit their requirements. In order to provide pharmacogenomic-based recommendations for a given drug, two possible types of input can be used: genotyping or exome or whole genome sequencing. Sequencing provides many more data points, including detection of mutations that prematurely terminate the synthesized protein (early stop codon).
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report