• Study Resource
  • Explore
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Course Syllabus
Course Syllabus

... C.1-Be able to distinguish one or two prototype drug(s) of each pharmacological group especially those of clinical importance. C.2-Acquire a comprehensive description of the major group of drugs as applied to medical practice and be sufficiently prepared to gather information on new drugs. C.3-Ident ...
Drug News Issue 58
Drug News Issue 58

... insert of its product with new safety information similar to the Health Canada's announcement. So far, the Department of Health (DH) has not received any local adverse drug reaction (ADR) report related to the product. In view of the Health Canada's announcement, a letter to healthcare professionals ...
Prior Authorization Guideline
Prior Authorization Guideline

... -ANDb. Oral anti-emetic drug is used as a full therapeutic replacement for IV anti-emetic drugs that would have been administered at the time of the chemotherapy treatment B. Part D – Nausea and Vomiting Associated with Cancer Chemotherapy 1. Marinol will be covered under Part D based on the followi ...
Process Chem Talk - San Diego Mesa College
Process Chem Talk - San Diego Mesa College

... The drug product is toxicity-tested in animals for safety. ...
Parallel Evolution of Adaptive Mutations in
Parallel Evolution of Adaptive Mutations in

... was not detected in any of the D0 corresponding isolates (Musset et al. 2006), even using a sensitive assay that detects one APR allele in the presence of up to 103 copies of the wild type susceptible allele (fig. S1 in supplementary data). This indicates that the APR allele was either absent or at ...
Report to the International Committee on Economic,
Report to the International Committee on Economic,

Tuberculosis - Current Advances in Development of New Drugs
Tuberculosis - Current Advances in Development of New Drugs

... 16. Dey T., et al. “Outcomes of clofazimine for the treatment of drug-resistant tuberculosis: a systematic review and meta-analysis”. Journal of Antimicrobial Chemotherapy 68.2 (2013): 284-293. 17. Lechartier B., et al. “Mode of Action of Clofazimine and Combination Therapy with Benzothiazinones a ...
11-2Probability and PunneTt Squares
11-2Probability and PunneTt Squares

... In genetics, the larger the number of offspring, the closer the resulting numbers will get to the expected values. ...
Journal Club: Trimethoprim-Sulfamethoxazole verses Placebo for
Journal Club: Trimethoprim-Sulfamethoxazole verses Placebo for

... of Bactrim DS) BID vs. placebo in patients with uncomplicated skin abscesses who underwent I&D and were treated on an outpatient basis. ...
otic suspension
otic suspension

... hearing, topical hypersensitivity reactions and red blisters on pinna. For a copy of the Material Safety Data Sheet (MSDS), for technical assistance or to report a suspected adverse drug reaction, contact Elanco Animal Health at 1-888-545-5973. Alternatively, suspected adverse drug reactions may be ...
An Example Case Study
An Example Case Study

... Oxycodone is a semi-synthetic opioid derived from the alkaloid thebaine, unlike most early opium-derived drugs which instead used the morphine or codeine alkaloids also found in the plant. Oxycodone was first synthesized in a German laboratory in 1916, a few years after the German pharmaceutical com ...
generic prescribing - when not to do it!
generic prescribing - when not to do it!

... Generic Prescribing: When not to do to do it! Generic prescribing is generally more cost-effective than prescribing by brand name. There are some circumstances however in which it is preferable to prescribe by brand name. Some common examples are given below but note that this list is not exhaustive ...
Over-the-Counter Drug Products
Over-the-Counter Drug Products

... ensure that they are properly labeled and that their benefits outweigh their risks. OTC drugs play an increasingly vital role in America's health care system by providing easy access to certain drugs that can be used safely without the help of a health care practitioner. This enables consumers to ta ...
BioSc 231 Exam 2 2003
BioSc 231 Exam 2 2003

... Bonus Question (4 pts) An Arabidopsis thaliana flowering mutation has been generated in the Columbia (Col) line. The mutant line was then crossed with a wild-type Landsberg erectus (Ler) line to generate the F1 generation. The F1 generation was allowed to self to produce the F2 generation. F2 plant ...
PHS 398 (Rev. 9/04), Continuation Page
PHS 398 (Rev. 9/04), Continuation Page

... unacceptable delay to the administration of medication. Although some hospitals have programs in place in which a pharmacist responds to the ED for cardiac arrests or trauma team activations, few have reported programs which involve a clinical pharmacist assigned exclusively to the emergency departm ...
Text S1.
Text S1.

... individuals. The PI is an estimate of the probability that two unrelated individuals drawn at random will by chance have the same MLG [48]. Individual PI’s are calculated for each locus and an overall PI for all loci is the product of each individual locus PI. PI values between 0.01 – 0.0001 are bel ...
Tuberculosis Adverse Drug Events
Tuberculosis Adverse Drug Events

... Athralgias: Common with PZA, INH, fluroquinalones, Rifabutin especially with high dose. Can be due to electrolyte abnormality. May occur with Amikacin, Streptomycin, Capreomycin. Gout: High uric acid in persons on PZA (with kidney disease). Tendonitis: stop exercise. Evaluate risk versus benefit of ...
File
File

... for 4 days; curve B the same total amount of drug given in eight equal doses; and curve C the same total amount of drug given in four equal doses. The drug has a halflife of 17hours and a volume of distribution of 20litres. Note that in each case a steady state is effectively reached after about 2da ...
ASSESSMENT AND ENHANCING ADHERENCE TO TREATMENT REGIMEN IN TUBERCULOSIS OUT PATIENTS
ASSESSMENT AND ENHANCING ADHERENCE TO TREATMENT REGIMEN IN TUBERCULOSIS OUT PATIENTS

... Medication adherence is defined as "the extent to which a person's behavior (in terms of taking medications, following diets, or executing lifestyle changes) coincides with medical or health advice." The term "adherence" assumes collaboration between the patient and the health care provider regardin ...
PRE0004 - PDRC | Prescription Drug Research Center
PRE0004 - PDRC | Prescription Drug Research Center

... 2. Agonist/Antagonist combinations – An opioid antagonist can be added to interfere with, reduce, or defeat the euphoria associated with abuse. The antagonist can be sequestered and released only upon manipulation of the product. For example, a drug product may be formulated such that the substance ...
1 Evaluation of Dual-Activity Opioid
1 Evaluation of Dual-Activity Opioid

... Before experimentation, a baseline reading for antinociception was taken for future comparison. After a baseline assessment using the hotplate and tail-flick assay, the mice were immediately injected with the designated drug. The mice were allowed to sit for 30 minutes so that the drug would have a ...
Antimycobacterial Drugs (抗分枝杆菌药)
Antimycobacterial Drugs (抗分枝杆菌药)

... active against atypical mycobacteria. Moxifloxacin is the most active against M tuberculosis by weight in vitro. Levofloxacin tends to be slightly more active than ciprofloxacin against M tuberculosis, ciprofloxacin is slightly more active against atypical mycobacteria. Fluoroquinolones are an impor ...
Heredity TEK 6F- Predict possible outcomes of various
Heredity TEK 6F- Predict possible outcomes of various

... TEK 6F- Predict possible outcomes of various genetic combinations such as monohybrid crosses, dihybrid crosses and non-Mendelian inheritance. ...
amoxicillin (a-mox-i-sill-in) - DavisPlus
amoxicillin (a-mox-i-sill-in) - DavisPlus

... bloody stools should be reported to health care professional promptly as a sign of pseudomembranous colitis. May begin up to several weeks following cessation of therapy. Lab Test Considerations: May causeqserum alkaline phosphatase, LDH, AST, and ALT concentrations. May cause false-positive direct ...
HEA Assay: Red Cell Blood Group Antigen
HEA Assay: Red Cell Blood Group Antigen

... The HEA assay is performed on DNA extracted from EDTA whole blood. The DNA region of interest is amplified by multiplex PCR, processed into single-stranded DNA and hybridized with allele-specific oligonucleotide probes to detect the relevant SNPs. The hybridization reaction is performed on a semicon ...
< 1 ... 917 918 919 920 921 922 923 924 925 ... 1254 >

Pharmacogenomics

Pharmacogenomics (a portmanteau of pharmacology and genomics) is the study of the role of genetics in drug response. It deals with the influence of acquired and inherited genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with drug absorption, distribution, metabolism and elimination, as well as drug receptor target effects. The term pharmacogenomics is often used interchangeably with pharmacogenetics. Although both terms relate to drug response based on genetic influences, pharmacogenetics focuses on single drug-gene interactions, while pharmacogenomics encompasses a more genome-wide association approach, incorporating genomics and epigenetics while dealing with the effects of multiple genes on drug response.Pharmacogenomics aims to develop rational means to optimize drug therapy, with respect to the patients' genotype, to ensure maximum efficacy with minimal adverse effects. Through the utilization of pharmacogenomics, it is hoped that drug treatments can deviate from what is dubbed as the “one-dose-fits-all” approach. It attempts to eliminate the trial-and-error method of prescribing, allowing physicians to take into consideration their patient’s genes, the functionality of these genes, and how this may affect the efficacy of the patient’s current and/or future treatments (and where applicable, provide an explanation for the failure of past treatments). Such approaches promise the advent of ""personalized medicine""; in which drugs and drug combinations are optimized for each individual's unique genetic makeup. Whether used to explain a patient’s response or lack thereof to a treatment, or act as a predictive tool, it hopes to achieve better treatment outcomes, greater efficacy, minimization of the occurrence of drug toxicities and adverse drug reactions (ADRs). For patients who have lack of therapeutic response to a treatment, alternative therapies can be prescribed that would best suit their requirements. In order to provide pharmacogenomic-based recommendations for a given drug, two possible types of input can be used: genotyping or exome or whole genome sequencing. Sequencing provides many more data points, including detection of mutations that prematurely terminate the synthesized protein (early stop codon).
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report