• Study Resource
  • Explore
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
The Economy of Nature 6/e
The Economy of Nature 6/e

... Darwin’s finches ...
New and alternative epilepsy treatments: Olgica Laban
New and alternative epilepsy treatments: Olgica Laban

... are compared with similar patients receiving a different treatment-usually an inactive substance (placebo), or a different drug. • randomized-subjects are randomly allocated to receive one or other of the alternative treatments under study (like tossing a coin) • Blinded - both tester and subject ar ...
1 - Central Texas Nephrology Associates
1 - Central Texas Nephrology Associates

... Health Information for a purpose (described in this document) other than treatment, payment, or health care operations. I have read this authorization and understand what information will be used or disclosed, who may use and disclose the information, and the recipient(s) of that information. I unde ...
Family Education Rights and Privacy Act (FERPA)
Family Education Rights and Privacy Act (FERPA)

... be conducted on a regular basis as determined by the School. The School reserves the right every three to six weeks to have a reasonable number of students from the student body to be randomly tested for illegal substances. The School also conducts “for cause” drug tests based upon the finding of re ...
Genetics
Genetics

... environments. Greater variation within the species makes a population better suited to adaptation to changes in the environment. ...
Opioid Overdose Costs - Michigan State University College of Nursing
Opioid Overdose Costs - Michigan State University College of Nursing

... Most deaths are among opiate users who are in their late twenties to early thirties and have been actively using for the past five to ten years ...
Herbal Compositions for Appetite Suppression and Weight
Herbal Compositions for Appetite Suppression and Weight

... effective to slice the excess weight. However, for most, besides being too expensive, the long term uses of these drugs are marred by their severe adverse toxicities. In fact, the principal reason for drug withdrawals has been due to concerns over safety rather than the effect on body weight. For ex ...
Rimonabant, a novel drug for the treatment of
Rimonabant, a novel drug for the treatment of

... risk factors in patients with obesity or overweight with diabetes type 2 and/or dyslipidemia, have been approved in Argentina Both obese and overweighted persons with associated diabetes and/or dyslipidemia will be able to receive it as a supplement to diet and physical activity. Clinical studies wi ...
ONE-YEAR DIOSMIN THERAPY (600 MG) IN PATIENTS WITH
ONE-YEAR DIOSMIN THERAPY (600 MG) IN PATIENTS WITH

... Chronic venous insufficiency (CVI) is increasingly affecting more and more patients, usually in their prime of life. This is most often a result of negligent examination overlooking varicose veins in different stages of development that present with edema, subfascial tension of the lower legs and, i ...
Opiates lecture opiatesONLY
Opiates lecture opiatesONLY

... Opiate block exocytosis of regulator, allowing dopamine release (two negative make a positive) ...
No Slide Title
No Slide Title

... families about the possibilities of events and the related signs and symptoms is suggested. A physician-led informed consent process is critical for the patient and their family. ...
Biol 211 (2) Chapter 14 KEY
Biol 211 (2) Chapter 14 KEY

... a. Pure-lines are homozygous and always produce offspring with the same phenotype. Hybrids are heterozygous.a b. Homozygous and heterozygous describe an organisms alleles, therefore it describes their genotype. However, the phenotype is affected by whether the genotype is homozygous or heterozygous. ...
Background Methods Results B. Hauns1, A. Mais1, R
Background Methods Results B. Hauns1, A. Mais1, R

... a shortening of the PR and QT intervals were found in a dose-dependent manner. However, at the highest dose level of 800 mg, no decrease in PR interval was observed after drug administration despite an HR increase. Slowing of atrioventricular conduction might be caused by the increased vagal tone in ...
Chapter 5 Drug Toxicity
Chapter 5 Drug Toxicity

recessive genetic conditions
recessive genetic conditions

... This is information for bull buyers about the recessive genetic conditions, Arthrogryposis Multiplex (AM), Hydrocephalus (NH), Contractural Arachnodactyly (CA) and Developmental Duplications (DD). Putting undesirable Genetic Recessive Conditions in perspective All animals, including humans, carry si ...
PATIENT INFORMATION LEAFLET NELABOCIN CEFUROXIME
PATIENT INFORMATION LEAFLET NELABOCIN CEFUROXIME

... Cefuroxime axetil may be used in elderly patients. 2.4.3 Pregnancy: In experimental studies, no embryopathies or teratogenesis caused by cefuroxime axetil were reported but as with all drugs, it should be administered with caution during the first months of pregnancy. 2.4.4 Lactation: Cefuroxime is ...
Forensic Counselor Ed Course Part 1
Forensic Counselor Ed Course Part 1

... b. self-soothing c. self-medication d. none of the above 20. People with this disorder may have rigid attitudes, are not flexible, and may lack the ability to show proper responses to people and situations. Their outlook of the world is very narrow and social life is very difficult for them, even th ...
7.1 Chromosomes and Phenotype
7.1 Chromosomes and Phenotype

... • Read the quote in small black text (under • connecting concepts) on page 199. Why is • there such a variation in eye color? ...
President Clinton Comes to Cal (Jan. 29, 2002)
President Clinton Comes to Cal (Jan. 29, 2002)

... Perhaps they have not scarred their wayward children so much as given them bad genes. Maybe it was not their superior parenting skills that produced that Nobel laureate. Whether a new emphasis on genes will breed tolerance or bigotry for inborn differences remains an open question. If a trait like b ...
Inherited Change
Inherited Change

... One from mum and one from dad. Bivalent – when the homologous chromosomes have replicated they join together by a chiasma and this forms a bivalent made of 4 chromatids. Crossing over – the non-sister chromatids that lie next to each other in the bivalent may join temporarily and then break off swop ...
Pharmacometrics and Biostatistics Interactions at the FDA
Pharmacometrics and Biostatistics Interactions at the FDA

... Example contributed by John Lawrence, DJ Marathe, James Hung, Sue-Jane Wang ...
Antidepressants /Antiepileptic drugs
Antidepressants /Antiepileptic drugs

... space, the use of a transcutaneous electrical nerve stimulator (TENS unit) . Since there is very little research data on the treatment of chronic low back pain, a single best treatment has yet to be determined particularly in chronic low back ache.(1) The development of newer classes of antidepressa ...
ALS Drug Guide
ALS Drug Guide

... Medicine and pharmacology is a constantly changing science and not all therapies are clearly established. New research changes drug and treatment therapies daily. The author and publisher of this document have has used his best efforts to provide information that is up-to-date and accurate and is ge ...
Please personalize this letter by updating the underlined items
Please personalize this letter by updating the underlined items

... seem to offer cost savings to the employer or plan sponsor, there are a number of other factors that also must be considered. For example, there very well may not be a CVS retail store that is convenient to all plan beneficiaries, and mail order is not a viable option for all medications. Some lette ...
Remember that
Remember that

... Here are some things to note: 1. the dominance deviation, d, can contribute to VA if q>p. 2. The additive genetic variation can be derived in terms of gene frequencies (p and q), the additive effects of alleles (a), and the dominance deviation (d). Thus there is a population genetic base to quantita ...
< 1 ... 913 914 915 916 917 918 919 920 921 ... 1254 >

Pharmacogenomics

Pharmacogenomics (a portmanteau of pharmacology and genomics) is the study of the role of genetics in drug response. It deals with the influence of acquired and inherited genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with drug absorption, distribution, metabolism and elimination, as well as drug receptor target effects. The term pharmacogenomics is often used interchangeably with pharmacogenetics. Although both terms relate to drug response based on genetic influences, pharmacogenetics focuses on single drug-gene interactions, while pharmacogenomics encompasses a more genome-wide association approach, incorporating genomics and epigenetics while dealing with the effects of multiple genes on drug response.Pharmacogenomics aims to develop rational means to optimize drug therapy, with respect to the patients' genotype, to ensure maximum efficacy with minimal adverse effects. Through the utilization of pharmacogenomics, it is hoped that drug treatments can deviate from what is dubbed as the “one-dose-fits-all” approach. It attempts to eliminate the trial-and-error method of prescribing, allowing physicians to take into consideration their patient’s genes, the functionality of these genes, and how this may affect the efficacy of the patient’s current and/or future treatments (and where applicable, provide an explanation for the failure of past treatments). Such approaches promise the advent of ""personalized medicine""; in which drugs and drug combinations are optimized for each individual's unique genetic makeup. Whether used to explain a patient’s response or lack thereof to a treatment, or act as a predictive tool, it hopes to achieve better treatment outcomes, greater efficacy, minimization of the occurrence of drug toxicities and adverse drug reactions (ADRs). For patients who have lack of therapeutic response to a treatment, alternative therapies can be prescribed that would best suit their requirements. In order to provide pharmacogenomic-based recommendations for a given drug, two possible types of input can be used: genotyping or exome or whole genome sequencing. Sequencing provides many more data points, including detection of mutations that prematurely terminate the synthesized protein (early stop codon).
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report